O-methylsalicylic Acid

Lingxian Chemical

Specifications

HS Code	401518
Chemical Formula	C8H8O3
Molar Mass	152.15 g/mol
Appearance	White to off - white solid
Odor	Odorless
Melting Point	88 - 90 °C
Boiling Point	284 - 286 °C
Solubility In Water	Slightly soluble
Solubility In Organic Solvents	Soluble in ethanol, ether, chloroform
Acidity Pka	Approx. 3.97
Density	1.263 g/cm³
Name	O - methylsalicylic Acid
Chemical Formula	C8H8O3
Molar Mass	152.15 g/mol
Appearance	White to off - white solid
Odor	Odorless
Melting Point	89 - 92 °C
Boiling Point	277 °C
Solubility In Water	Slightly soluble
Solubility In Organic Solvents	Soluble in ethanol, ether, etc.
Acidity Pka	3.96
Density	1.271 g/cm³
Name	O-methylsalicylic Acid
Chemical Formula	C8H8O3
Molar Mass	152.15 g/mol
Appearance	White to off - white solid
Odor	Odorless
Solubility In Water	Slightly soluble
Melting Point	105 - 107 °C
Boiling Point	300.8 °C at 760 mmHg
Density	1.263 g/cm³
Pka	9.78
Flash Point	130.8 °C
Chemical Formula	C8H8O3
Molar Mass	152.15 g/mol
Appearance	White to off - white solid
Melting Point	72 - 74 °C
Boiling Point	283 - 284 °C
Solubility In Water	Slightly soluble
Solubility In Organic Solvents	Soluble in ethanol, ether
Odor	Faint, characteristic
Acidity	Weakly acidic
Stability	Stable under normal conditions
Name	O - methylsalicylic Acid
Chemical Formula	C8H8O3
Molar Mass	152.15 g/mol
Appearance	White to off - white solid
Odor	Odorless
Melting Point	104 - 106 °C
Boiling Point	283 - 284 °C
Solubility In Water	Slightly soluble
Solubility In Organic Solvents	Soluble in ethanol, ether
Pka	9.89
Flash Point	131.7 °C
Chemical Formula	C8H8O3
Molar Mass	152.15 g/mol
Appearance	White to off - white crystalline powder
Odor	Odorless
Melting Point	102 - 104 °C
Solubility In Water	Slightly soluble
Solubility In Organic Solvents	Soluble in ethanol, ether, chloroform
Pka Value	3.96
Boiling Point	283 - 284 °C
Density	1.253 g/cm³
Chemical Formula	C8H8O3
Molar Mass	152.15 g/mol
Appearance	White to off - white solid
Melting Point	103 - 106 °C
Boiling Point	288 °C
Solubility In Water	Slightly soluble
Solubility In Organic Solvents	Soluble in ethanol, ether
Odor	Odorless
Acidity	Weakly acidic
Pka	3.96
Name	O-methylsalicylic Acid
Chemical Formula	C8H8O3
Molar Mass	152.15 g/mol
Appearance	White to off - white crystalline powder
Odor	Odorless
Melting Point	107 - 111 °C
Solubility In Water	Slightly soluble
Solubility In Organic Solvents	Soluble in ethanol, ether
Pka	9.43
Flash Point	137.5 °C
Stability	Stable under normal conditions
Chemical Formula	C8H8O3
Molar Mass	152.15 g/mol
Appearance	White to off - white solid
Odor	Odorless (usually)
Melting Point	88 - 92 °C
Boiling Point	283 - 284 °C
Solubility In Water	Slightly soluble
Solubility In Organic Solvents	Soluble in ethanol, ether
Pka Value	3.96
Density	1.25 g/cm³ (approximate)
Chemical Formula	C8H8O3
Molar Mass	152.15 g/mol
Appearance	White to off - white crystalline powder
Odor	Slight, characteristic
Melting Point	88 - 92 °C
Boiling Point	283 - 284 °C
Solubility In Water	Slightly soluble
Solubility In Organic Solvents	Soluble in ethanol, ether, chloroform
Pka	3.94
Density	1.263 g/cm³
Chemical Formula	C8H8O3
Molar Mass	152.15 g/mol
Appearance	White to off - white crystalline powder
Odor	Odorless
Melting Point	107 - 111 °C
Solubility In Water	Slightly soluble in water
Solubility In Organic Solvents	Soluble in ethanol, ether, chloroform
Pka	3.96
Boiling Point	283 - 284 °C
Density	1.312 g/cm³
Chemical Formula	C8H8O3
Molar Mass	152.15 g/mol
Appearance	White to off - white solid
Odor	Characteristic
Solubility In Water	Slightly soluble
Melting Point	88 - 92 °C
Boiling Point	283 - 284 °C
Density	1.25 g/cm³
Pka	3.96
Flash Point	144.9 °C
Name	O - methylsalicylic Acid
Chemical Formula	C8H8O3
Molar Mass	152.15 g/mol
Appearance	White to off - white solid
Melting Point	107 - 109 °C
Boiling Point	279 - 280 °C
Solubility In Water	Slightly soluble
Solubility In Organic Solvents	Soluble in ethanol, ether, etc.
Odor	Odorless
Pka	3.96
Chemical Formula	C8H8O3
Molar Mass	152.15 g/mol
Appearance	White to off - white solid
Odor	Odorless
Melting Point	108 - 112 °C
Boiling Point	277 - 278 °C
Solubility In Water	Slightly soluble in water
Solubility In Organic Solvents	Soluble in ethanol, ether, chloroform
Acidity	Weak acid
Flash Point	144.5 °C
Chemical Formula	C8H8O3
Molar Mass	152.15 g/mol
Appearance	White to off - white solid
Odor	Odorless
Melting Point	103 - 105 °C
Solubility In Water	Slightly soluble
Solubility In Organic Solvents	Soluble in ethanol, ether, chloroform
Pka Value	Around 3.96
Boiling Point	283 - 284 °C
Density	1.254 g/cm³
Name	O - methylsalicylic Acid
Chemical Formula	C8H8O3
Molar Mass	152.15 g/mol
Appearance	White to off - white solid
Odor	Odorless
Solubility In Water	Slightly soluble
Melting Point	83 - 87 °C
Boiling Point	278 - 280 °C
Density	1.25 g/cm³
Flash Point	148.9 °C
Acidity Pka	3.89
Chemical Formula	C8H8O3
Molar Mass	152.15 g/mol
Appearance	White to off - white solid
Odor	Odorless
Solubility In Water	Slightly soluble
Solubility In Organic Solvents	Soluble in ethanol, ether
Melting Point	88 - 90 °C
Boiling Point	283 - 284 °C
Density	1.258 g/cm³
Acidity Pka	3.96
Flash Point	157.1 °C
Chemical Formula	C8H8O3
Molar Mass	152.15 g/mol
Appearance	White to off - white crystalline powder
Odor	Odorless
Melting Point	88 - 92 °C
Boiling Point	277 °C
Solubility In Water	Slightly soluble
Solubility In Organic Solvents	Soluble in ethanol, ether, chloroform
Pka Value	2.98
Density	1.24 g/cm³

Packing & Storage

Packing	100g of O - methylsalicylic Acid packaged in a sealed, chemical - resistant container.
Storage	O - methylsalicylic acid should be stored in a cool, dry place, away from direct sunlight and heat sources. Keep it in a well - sealed container to prevent moisture absorption and contact with air, which could lead to oxidation or degradation. Store it separately from incompatible substances, like strong oxidizers and bases, to avoid chemical reactions.
Shipping	O - methylsalicylic acid should be shipped in tightly sealed, corrosion - resistant containers. Ensure proper labeling indicating it's a chemical. Ship via approved carriers following regulations for hazardous or chemical goods.

Free Quote

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General Information

Frequently Asked Questions

What is the chemical structure of O-methylsalicylic Acid?

O-methylsalicylic acid (O-methylsalicylic acid), its molecular structure is based on the structure of salicylic acid, which is formed by connecting a methyl group to the oxygen atom of the hydroxyl group.
The structure of salicylic acid is based on the benzene ring, which has a carboxyl group (-COOH) and a hydroxy group (-OH) in the ortho position. O-methylsalicylic acid, on the other hand, is the oxygen of the hydroxyl group connected to the methyl group (-CH 🥰), which gives the compound unique physical and chemical properties.
This structure makes O-methylsalicylic acid different from salicylic acid. From the perspective of chemical activity, due to the introduction of methyl groups, the activity of hydroxyl hydrogen atoms is reduced, and the acidity is slightly reduced. In the spatial structure, the presence of methyl groups changes the molecular shape and steric resistance, which affects the interaction between molecules.
From the perspective of reactivity, this structural change may affect its ability to participate in various chemical reactions, such as esterification, acylation, etc. Compared with salicylic acid, it may have different performance. In short, O-methyl salicylic acid has unique applications and reaction characteristics in the fields of medicine, chemical industry and other fields due to its specific chemical structure.

What are the main uses of O-methylsalicylic Acid?

O-methylsalicylic acid, also known as o-methoxybenzoic acid, has a wide range of uses.
First, in the field of medicine, it can be used as a key intermediate for drug synthesis. Because it has a specific chemical structure and activity, it can participate in the construction of many drug molecules. For example, in the preparation of some antipyretic, analgesic and anti-inflammatory drugs, O-methylsalicylic acid can be ingeniously converted into ingredients with specific pharmacological activities through a series of reactions, helping the drug to exert its efficacy and relieve pain for patients.
Second, in the dye industry, O-methylsalicylic acid also has important uses. It can be used as a raw material for the synthesis of certain dyes, and its structural characteristics enable it to endow dyes with unique color and stability. After chemical modification and reaction, dyes suitable for dyeing different fabrics can be generated, which makes the dyed fabrics bright and long-lasting, and improves the quality and application range of dye products.
Third, in the field of organic synthesis, O-methylsalicylic acid is often used as a building block for organic synthesis. With its functional group properties, it can react with a variety of reagents to construct complex organic compound structures. Whether it is building carbon-carbon bonds or introducing other functional groups, O-methylsalicylic acid can play a key role in enabling organic chemists to synthesize novel organic materials with special properties and promote the development of organic synthesis chemistry.

What is the Production Method of O-Methylsalicylic Acid?

The method of preparing O-methyl salicylic acid is a chemical synthesis. Salicylic acid is often used as the starting material and is formed by specific chemical conversion steps.
One method is to react with dimethyl sulfate under the catalysis of a base. First, the salicylic acid is placed in an appropriate reaction vessel, and an appropriate amount of alkali, such as potassium carbonate, sodium carbonate, etc., is added to create an alkaline reaction environment. The base can deprotonate the phenolic hydroxyl group of salicylic acid and enhance its nucleophilicity. Then, dimethyl sulfate is slowly added. The methyl group in dimethyl sulfate is electrophilic and can react with the oxygen atom of the phenolic hydroxyl group of salicylate to generate O-methyl salicylic acid. This reaction requires attention to the control of the reaction temperature, the proportion of reactants and the reaction time. If the temperature is too high, side reactions may occur; if the ratio is not appropriate, the yield will be poor; if the time is not suitable, it will be difficult to achieve the ideal degree of reaction.
There are also those who use iodomethane instead of dimethyl sulfate. Under similar alkaline conditions, the methyl group of iodomethane can react with the phenolic hydroxyl group of salicylate. The reactivity of iodomethane is quite high, but its toxicity should not be underestimated. Therefore, extra caution should be taken during operation, carried out in a well-ventilated place, and appropriate protective measures should be taken.
In addition, there are also those who use phase transfer catalysts In the heterogeneous reaction system, the phase transfer catalyst can promote the effective contact and reaction of the reactants between different phases, improve the reaction efficiency, and also help to improve the purity and yield of the product.
In short, the method of preparing O-methylsalicylic acid, although there are various paths, all of them need to be based on the reaction principle and fine regulation of the reaction conditions to obtain satisfactory results.

What are the precautions for O-methylsalicylic Acid during use?

O-methylsalicylic acid, when using, many things should be paid attention to.
Its nature is a chemical substance with certain chemical activity. First and foremost, protection is essential. When handling this object, it should be properly prepared as protective equipment, such as gloves, goggles, etc. Gloves should be made of chemically resistant materials to avoid skin contact and invasion. Goggles can protect the eyes from splashing damage to prevent accidental entry and damage to eyesight.
Furthermore, use in well-ventilated areas. If this substance or volatile gas is blocked in the space, the gas will accumulate, or cause respiratory discomfort, and even endanger health. Ventilation is smooth, allowing the gas to escape in time and ensuring the safety of the environment.
Also, storage needs to be cautious. It should be placed in a cool, dry place, away from fire and heat sources. Due to its chemical properties, it is dangerous to be heated or exposed to open flames, causing combustion or even explosion. And it must be placed separately from other chemicals to prevent improper reactions.
When taking it, measure it accurately and take it according to the required amount. Do not overdo it. If there is any excess, it should not be discarded at will, and it should be properly disposed of according to regulations. Cover it because it may pollute the environment, and dispose of it in compliance to ensure that the environment is safe.
During the operation, always pay attention to its reaction phenomenon. If there is abnormal fever, discoloration, gas production, etc., stop the operation, check the cause carefully, and do not act rashly to avoid disaster.

What is the market outlook for O-methylsalicylic Acid?

O-methylsalicylic acid (O-methylsalicylic Acid), its market prospects are as follows.
Looking at the current chemical business, O-methylsalicylic acid has its uses in various fields. As a medicine, it can be used as a raw material for synthetic drugs. Due to its specific chemical structure and properties, it can help to form a variety of drugs and be used to treat various diseases. Its demand in the pharmaceutical market is gradually on the rise with the importance of public health and the progress of pharmaceutical research and development.
Furthermore, in the field of fine chemicals, it can be used in the production of fragrances and preservatives. The use of fragrances can endow products with unique fragrance and add product charm; the power of preservatives can ensure the longevity of items and reduce the worry of spoilage. In these two ways, due to the rise of daily chemical, food and other industries, there is also a growing demand.
However, the market is changing, but there are also challenges. The method of production is related to cost and quality. If the technology is outdated, the cost is high and the quality is difficult to be excellent, the market opportunity will be lost. And competing products are all around, and other compounds with similar functions or new substitutes are eager to share the market.
Even if there are challenges, the future is still promising. Advanced technology, new applications or current, expanding market territory. And the voice of environmental protection is high, if it can fit the tide of green production and be produced by clean processes, it will win the favor of the market. Therefore, on the whole, O-methylsalicylic acid market prospects, opportunities and challenges coexist, good operators will be able to find business opportunities in the waves and expand a broad path.