Products

1,1,3,3-Tetramethylguanidine

Lingxian Chemical

Specifications

HS Code

858721

Name 1,1,3,3 - Tetramethylguanidine
Chemical Formula C5H13N3
Molar Mass 115.177 g/mol
Appearance Colorless to light yellow liquid
Odor Pungent
Density 0.916 g/cm³ (at 20 °C)
Boiling Point 160 - 162 °C
Melting Point -30 °C
Solubility In Water Miscible
Pka 12.4 (in water)
Flash Point 48 °C
Refractive Index 1.4665 (at 20 °C)
Packing & Storage
Packing 1,1,3,3 - Tetramethylguanidine in a 500 - mL bottle for chemical storage.
Storage 1,1,3,3 - Tetramethylguanidine should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly sealed container to prevent exposure to air and moisture, which could reactive or degrade the chemical. Store it separately from oxidizing agents and acids due to potential reactivity.
Shipping 1,1,3,3 - Tetramethylguanidine is typically shipped in sealed, corrosion - resistant containers. Due to its chemical properties, it requires careful handling during transit, adhering to strict regulations for hazardous chemicals.
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1,1,3,3-Tetramethylguanidine
General Information
Historical Development
1, 1, 3, 3-tetramethylguanidine is also a chemical substance. Tracing back to its origin, its research was still shallow in the academic community at the beginning, and little was known about it. However, over the years, various sages worked tirelessly. In the past, it was mostly limited to the exploration of basic properties. With the advance of science and technology, the research has gradually become better.
Since the beginning, only its rough nature has been known, and later scholars have used precise methods to study its structure and characteristics in detail. In the field of organic synthesis, it gradually shows its extraordinary ability. Because of its unique alkalinity and reactivity, it adds to organic synthesis. With the in-depth research and wider application, it has emerged in many fields such as chemical industry and medicine. The development of this substance is like a pearl gradually shining, making outstanding contributions to the progress of chemistry.
Product Overview
1,1,3,3-tetramethylguanidine is one of the unique properties of chemical compounds. Its structure is exquisite, and it is cleverly connected by tetramethyl and guanidine to form this unique shape. This substance has extraordinary uses in many fields. In the field of organic synthesis, it can be a strong base, catalyzing many reactions, making the reaction path smoother and the rate can be improved. In the field of material science, or participating in the construction of materials with special properties, it gives materials different characteristics. Its physical properties are also worthy of investigation. Its properties are stable, and under suitable conditions, it can be stored for a long time without deterioration. And because of its special structure and properties, it is often a key additive in the chemical production process, helping production to be more efficient and product quality to be improved. It is an important substance that cannot be ignored in chemical research and industrial applications.
Physical & Chemical Properties
1,1,3,3-tetramethylguanidine is an organic compound. Its physical properties are colorless to light yellow transparent liquid at room temperature, weakly alkaline, and has a special odor. The boiling point is quite high, about 169 ° C, because of the strong intermolecular force. Its solubility is good, soluble in water and various organic solvents, because its molecular structure contains polar groups, which can form hydrogen bonds or other forces with water molecules and organic solvent molecules.
In terms of its chemical properties, 1,1,3,3-tetramethylguanidine has good alkalinity and can form salts with acids. In organic synthesis, it is often used as an alkali catalyst because of its moderate alkalinity and suitable steric resistance, which can effectively promote many reactions, such as nucleophilic substitution and elimination reactions. And because of its high stability, it is not easy to decompose under general conditions, so it is widely used in chemical, pharmaceutical and other fields.
Technical Specifications & Labeling
1, 1, 3, 3-tetramethylguanidine is also a chemical product. Its technical specifications and identification (commodity parameters) are related to the advantages and disadvantages of this product and its use.
Looking at its technical specifications, it is necessary to accurately control the synthesis method, the ratio of raw materials must be consistent, and the temperature and time of the reaction are all fixed. In this way, a pure product can be obtained. On the label, when its properties, such as color, taste, state, and SD content, purity and other parameters, make it clear to the user.
In ancient words, to make excellent 1, 1, 3, 3-tetramethylguanidine, all the details cannot be ignored. From the selection of materials to the control of the process, all must be carried out in accordance with regulations, and the logo should also be detailed to meet the requirements of technical specifications and labels, and can be trusted by users.
Preparation Method
The preparation of 1,1,3,3-tetramethylguanidine involves raw materials and production processes, reaction steps and catalytic mechanisms. In the past, the preparation of this product was often based on specific raw materials and delicate methods. The selection of raw materials is very critical, such as selecting a suitable starting material and reacting through multiple steps.
At the beginning, the raw materials are mixed in a specific ratio and put into a special reactor. Under precise temperature control and pressure control, the reaction is initiated. In the meantime, the specific catalytic mechanism comes into play to accelerate the reaction process.
The reaction steps are rigorous and orderly. First, the raw materials are initially converted through a certain step of reaction, and then the reaction is deepened in other steps, so that the product gradually becomes purified. After the reaction is completed, the high purity of 1, 1, 3, 3-tetramethylguanidine is obtained through fine separation and purification process. This preparation method has been repeatedly tempered and matured, laying the foundation for its wide application.
Chemical Reactions & Modifications
1,1,3,3-tetramethylguanidine is also a chemical substance. In the chemical reaction and modification, I will try to study it. Its reaction, or involving nucleophilic attack, or the migration of electrons, the mechanism is complicated.
To understand its modification, it is necessary to observe its structure. This guanidine has a special nitrogen heterocycle, and the distribution of electron clouds is different. By means of substitution, a functional group can be added to change its properties. Such as introducing a polar base, or increasing its water-soluble ability; adding a hydrophobic chain can change the properties of the interface.
The reaction conditions are also heavy. The rise and fall of temperature, the presence or absence of catalysis, all affect the direction and speed of the reaction. Only by observing its laws and adjusting conditions can we produce products with excellent performance, which are widely used in chemical and pharmaceutical fields.
Synonyms & Product Names
1, 1, 3, 3 - Tetramethylguanidine, this substance is widely used in the field of chemical industry. Its synonymous name, or tetramethylguanidine. The name of the commodity, also follows this meaning.
tetramethylguanidine, with strong alkalinity, is often a catalyst in the process of organic synthesis. Its activity can promote the progress of many reactions, such as ester exchange, cyclization and other reactions, all rely on its help. In the polymerization reaction, it can also play a role in optimizing the performance of the polymer.
Because of its unique properties, it plays a significant role in the research and development and production of chemical products. Chemical products, or because of the participation of tetramethylguanidine, improve the quality and efficiency. Many researchers are dedicated to exploring more applications of it, with the aim of exploring new frontiers in the chemical industry and contributing to the development of the industry.
Safety & Operational Standards
1, 1, 3, 3-tetramethylguanidine, chemical products are also used. In its experiments and applications, safety and operating standards are of paramount importance.
Where this material is involved, the safety of the environment should be the first priority. The experimental site should be well ventilated to avoid risks caused by its gas accumulation. And a good exhaust device should be prepared to quickly discharge exhaust gases and keep the space fresh.
When taking it, the law must be followed. The operator needs appropriate protective equipment, such as gloves, goggles, protective clothing, etc. Gloves should be selected that are resistant to corrosion. The goggles can prevent it from splashing the eyes, and the protective clothing should be protected all over the body to avoid contact with the skin.
When storing, there are also regulations. It should be placed in a cool, dry and well ventilated place, away from fire and heat sources. Do not mix with strong oxidants, acids, etc., to prevent their chemical reactions and cause emergencies.
If there is such a thing spilled during the experiment, do not panic. Quickly cut off the fire source and prohibit all open flames. Immediately start ventilation and evacuate people. A small amount of sprinkling can be covered with sand, dry lime, etc., and collected in a closed container. If a large amount is spilled, the embankment will be blocked, and it will be transferred to a special collector with an explosion-proof pump for proper disposal.
During the operation process, strictly abide by the procedures. Accurate measurement, control of its reaction conditions, temperature, pressure and time must be carefully observed. After the reaction is completed, the product treatment should not be ignored. According to relevant laws, harmless disposal.
In this way, strict management and careful treatment can ensure the safety of the use of 1,1,3,3-tetramethylguanidine, avoid disasters, and promote the stability of chemical research and application.
Application Area
1, 1, 3, 3-tetramethylguanidine is also a wonder of chemical chemistry. Its application is very good, and it has an extraordinary performance in all fields.
In the realm of chemical synthesis, it often uses force-based catalysis to help multiple reactions. With the ability to synthesize, it can accelerate the reaction rate, improve the yield of the chemical, and enable the chemical industry to gain the best of the molecules.
In the field of material science, it also has its own uses. It can be used to improve the performance of special materials, influence the properties of materials, and provide assistance in the research of new materials.
In the process of material research, it can be used to reverse the components, playing an important role in the synthesis of active ingredients, and helping the research to move forward.
This compound, with its unique properties, has an exceptional value for development in a wide range of applications, promoting the development of chemical and phase-related families.
Research & Development
Since modern times, chemical refinement, all kinds of new substances have been produced. 1, 1, 3, 3 - Tetramethylguanidine This substance is also studied by us.
We have carefully observed its properties and explored its synthesis method. At the beginning, the progress was difficult, and the ratio of raw materials and the temperature and pressure of the reaction all need to be carefully weighed. A little carelessness will fall short.
However, the way of scientific research lies in persistence. After months of study and repeated trials, the method of optimization is finally obtained. Its yield is gradually increasing, and the quality is also excellent.
Looking at its application, it has a significant effect in the field of organic synthesis. It can be a catalyst for many reactions, accelerate the reaction process, and improve the purity of the product.
Looking to the future, we hope to continue to expand based on this. Or we can emerge in the creation of new materials and drug research and development, contributing to the development of chemistry, helping the prosperity of the discipline, and benefiting the world.
Toxicity Research
Guanfu 1, 1, 3, 3 - Tetramethylguanidine The study of its toxicity is related to the health of people's livelihood, and it is also important for our chemical researchers. Today, we carefully examine its properties and observe its toxicity in various environments.
After repeated experiments, we observe its response to the organism, or damage the function of the viscera, or disordered the order of the cells. Although its amount is small, no significant harm is seen, but it accumulates over time, or there is potential worry. The symptoms of its poison are initially fatigue and mental fatigue, followed by various diseases.
We should be careful about its preparation and use, and strictly set regulations to prevent its escape and protect everyone from it. We must ensure that this chemical substance, although effective, does not cause harm to the world, so as to achieve its benefits and avoid its harmful environment.
Future Prospects
In the future, in 1, 1, 3, 3 - Tetramethylguanidine this thing, our generation of scientific researchers are full of hope. Its unique nature, the field of application, can not be limited. Or in the manufacture of high-tech materials, add its toughness; or in the production of exquisite drugs, increase its miraculous effect. Although the knowledge of the present is still limited, with time, we will be able to explore its deep secrets and display its power. Let it shine in various fields, for the benefit of the world, for the advancement of science and technology, and add bricks and tiles. So that future generations can benefit from it and feel the diligence and expectations of our generation today.
Frequently Asked Questions
What are the physical properties of 1,1,3,3-tetramethylguanidine?
1% 2C1% 2C3% 2C3-tetrabutylammonium is a type of ionic liquid. Its physical properties are as follows:
A transparent liquid that is usually colorless to light yellow in appearance, due to the internal molecular arrangement and light action. It is a liquid at room temperature and pressure. The maintenance of this state is due to the weak interaction between anions and cations, resulting in a relatively low melting point of about - 20 ° C to 20 ° C. This property allows the substance to remain a flowing liquid at common ambient temperatures, making it convenient for many experimental operations and industrial applications.
The density of this substance is about 0.9-1.1 g/cm ³, which is similar to that of water, but its density is slightly different due to molecular structure differences. Its viscosity is higher than that of ordinary organic solvents, about 10-100 mPa · s. Due to the strong interaction force between ions, the resistance of molecules to flow increases, which is manifested as higher viscosity.
In terms of solubility, 1% 2C1% 2C3% 2C3-tetrabutylammonium is soluble in a variety of organic solvents, such as acetonitrile, acetone, etc., and can also be miscible with some polar organic solvents. It also has a certain solubility in water, because the anions and cations of ionic liquids can form hydrogen bonds or other interactions with water molecules, causing them to disperse or dissolve in the aqueous phase.
In addition, 1% 2C1% 2C3% 2C3-tetrabutylammonium has good thermal stability, and its chemical structure and physical properties do not change significantly within a certain temperature range. It can usually withstand high temperatures from 200 ° C to 300 ° C. This property makes it important for high-temperature chemical reactions or separation processes. And because it is composed of ions, it has certain conductivity and has potential applications in the field of electrochemistry.
What are the chemical properties of 1,1,3,3-tetramethylguanidine?
1% 2C1% 2C3% 2C3-tetramethylcyclobutane is an organic compound with the following chemical properties:
First, it has the commonality of saturated hydrocarbons. Its molecular structure contains carbon-carbon single bonds and carbon-hydrogen bonds, and its properties are relatively stable. Under normal temperature and pressure, it is usually difficult to react with strong acids, strong bases and strong oxidants. In case of common acids and bases such as sodium hydroxide and sulfuric acid, there is no significant change under normal conditions. Due to the high bond energy of carbon-carbon single bonds and carbon-hydrogen bonds, specific conditions are required to break.
Second, substitution reactions can occur. When exposed to light or heat and there are halogen elements, hydrogen atoms in the molecule are easily replaced by halogen atoms. For example, when it is placed under light conditions and introduced into chlorine gas, chlorine atoms will gradually replace hydrogen atoms on the ring to form chlorine-containing substituents. This reaction mechanism is a free radical reaction. Light prompts chlorine molecules to crack into chlorine radicals. Chlorine radicals interact with tetramethylcyclobutane molecules to capture hydrogen atoms and generate new free radicals. The new free radicals then react with chlorine molecules, and so on to complete the substitution reaction.
Third, thermal stability. Although tetramethylcyclobutane is relatively stable, under high temperature conditions, its ring structure may undergo a ring-opening reaction. Due to the existence of ring tension in cycloalkanes, high temperature provides energy to break carbon-carbon bonds, open rings, and form chain compounds. For example, under specific high temperatures and catalysts, tetramethylcyclobutane ring-opens to form corresponding chain olefins or other products, which is of great significance for adjusting the molecular structure and preparing specific organic compounds.
What are the applications of 1,1,3,3-tetramethylguanidine in industry?
1% 2C1% 2C3% 2C3-tetramethylpiperidine has the following main applications in industry:
This substance has extraordinary uses in many fields of industry. In the field of polymer materials, it is often used as a light stabilizer. Because polymer materials are susceptible to ultraviolet rays under lighting conditions, they cause molecular chain fracture and performance deterioration. The special structure of 1% 2C1% 2C3% 2C3-tetramethylpiperidine can effectively trap free radicals, inhibit the photooxidation process, and greatly improve the photoaging resistance of polymer materials. For example, plastic products, after adding this substance, it can be used outdoors for a long time, which can also slow down the rate of discoloration and embrittlement and prolong the service life.
In the paint industry, it is also an important additive. Coatings face various environmental challenges during film formation and use. 1% 2C1% 2C3% 2C3 - tetramethylpiperidine can enhance the weather resistance of coatings, resist ultraviolet rays, oxygen and other erosion, so that the coating can maintain good color and physical properties for a long time. Like building exterior wall coatings, after adding this additive, it can still maintain aesthetics and protective functions after years of wind and sun exposure.
In the rubber industry, 1% 2C1% 2C3% 2C3 - tetramethylpiperidine can be used as an antioxidant. When rubber products are used, they are susceptible to aging due to oxygen, heat, mechanical stress, etc., which are manifested as hardening, brittleness, and loss of elasticity. This substance can inhibit the aging reaction of rubber and prolong the storage and service life of rubber products. Adding this substance to rubber products such as automobile tires can significantly improve their durability.
What are the synthesis methods of 1,1,3,3-tetramethylguanidine?
1%2C1%2C3%2C3-%E5%9B%9B%E7%94%B2%E5%9F%BA%E8%83%8D, there are various preparation methods. One of the common ones is to react halogenated alkane and magnesium powder in anhydrous ether to make Grignard reagent, and then react with the corresponding carbonyl compound, which can be obtained after hydrolysis. For example, the appropriate halogenated ethane and magnesium powder are reacted in anhydrous ether under nitrogen protection and low temperature stirring to generate ethylmagnesium halogenated Grignard reagent, and then a carbonyl compound containing a specific structure is added, and the reaction is heated for a period of time. Finally, dilute acid is added to hydrolyze, and the product is separated and purified.
Another method of reacting with halogenated hydrocarbons under alkali catalysis is to use enol ethers or enamines. With a specific alkenol ether and halopropane, catalyzed by a strong base such as potassium tert-butanol, in a suitable organic solvent, the reaction is reacted at a certain temperature. After the reaction, the target product is obtained through neutralization, extraction, distillation and other steps.
can also be prepared by nucleophilic addition of alkynes. First, alkynes are added to hydrogen halide under the action of an appropriate catalyst to form halogenated olefins, and then nucleophilic addition with another reagent containing specific groups under basic conditions, and 1%2C1%2C3%2C3-%E5%9B%9B%E7%94%B2%E5%9F%BA%E8%83%8D is obtained after subsequent treatment. During the specific operation, the reaction conditions such as temperature, pressure, ratio of reactants, and catalyst dosage need to be precisely regulated according to the actual situation to ensure the efficient and smooth progress of the reaction, and improve the yield and purity of the product.
What are the precautions for using 1,1,3,3-tetramethylguanidine?
1%2C1%2C3%2C3-%E5%9B%9B%E7%94%B2%E5%9F%BA%E8%83%8D, this is a chemical substance, and many key matters need to be paid attention to during use.
First, because of its certain chemical activity, be sure to read the product description and safety manual in detail before use to clarify its chemical characteristics, scope of application and latent risk. Do not operate blindly to prevent danger due to ignorance.
Second, storage should be placed in a dry, cool and well-ventilated place, away from fire sources, heat sources and strong oxidants. Due to its special chemical structure, improper storage environment or chemical reactions can cause deterioration or safety accidents.
Third, protective measures are indispensable when using. Appropriate protective equipment should be worn, such as protective gloves, goggles, etc., to avoid direct contact of the substance with the skin and eyes. Because it may be irritating or corrosive to the human body, if inadvertently contacted, immediately rinse with plenty of water, and seek medical attention according to the specific situation.
Fourth, the operation process should be carried out under professional guidance or follow established operating procedures. Precisely control the dosage and reaction conditions. Due to improper dosage or deviation of reaction conditions, not only the expected effect will be affected, but also accidents may be caused.
Fifth, after use, the remaining substances and waste should be properly disposed of. It should not be discarded at will, and should be collected and disposed of in accordance with relevant regulations to prevent pollution to the environment. Due to its chemical properties or adverse impact on the ecological environment, it requires careful treatment.