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1-[(2-Chloro-1,3-Thiazol-5-Yl)Methyl]-2-Methyl-3-Nitroguanidine

Lingxian Chemical

Specifications

HS Code

919827

Chemical Name 1-[(2-Chloro-1,3-Thiazol-5-Yl)Methyl]-2-Methyl-3-Nitroguanidine
Molecular Formula C6H8ClN5O2S
Molecular Weight 249.68 g/mol
Appearance Typically a solid
Physical State At Room Temp Solid
Solubility Solubility characteristics vary depending on solvent
Melting Point Specific melting point data needed from literature
Boiling Point Specific boiling point data needed from literature
Vapor Pressure Low vapor pressure expected for a solid
Logp Hydrophobicity parameter data needed from literature
Pka Acid dissociation constant data needed from literature
Packing & Storage
Packing Packaged in a 1 - kg container: 1 -[(2 - Chloro - 1,3 - thiazol - 5 - yl)methyl]-2 - methyl - 3 - nitroguanidine
Storage 1 - [(2 - Chloro - 1,3 - Thiazol - 5 - Yl)Methyl] - 2 - Methyl - 3 - Nitroguanidine should be stored in a cool, dry place away from heat sources and direct sunlight. Keep it in a well - ventilated area to avoid the buildup of potentially harmful vapors. Store in a tightly closed container to prevent contact with moisture and oxygen, which could cause chemical degradation.
Shipping 1-(2 - Chloro - 1,3 - thiazol - 5 - yl)methyl - 2 - methyl - 3 - nitroguanidine must be shipped in accordance with strict chemical regulations. Packed securely to prevent leakage, transported by approved carriers handling hazardous chemicals with proper documentation.
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1-[(2-Chloro-1,3-Thiazol-5-Yl)Methyl]-2-Methyl-3-Nitroguanidine
General Information
Historical Development
1 - [ (2-chloro-1,3-thiazole-5-yl) methyl] - 2-methyl-3-nitroguanidine This compound first appeared in the field of chemical research, and its beginning was also explored by scholars in the vast abundance of knowledge, and the period was rewarded. At the beginning of the research, many difficulties were encountered, and the path of exploration was bumpy. However, relentless research was made to gradually understand its nature.
As the years passed, many talents devoted themselves to this, and their structure and properties were analyzed in detail. With the advance of science and technology, the method of research became more and more exquisite. The simple method in the past was gradually replaced by the precise technique. Everyone tried it repeatedly in the laboratory, striving to improve it.
As a result, the understanding of this compound has deepened, and its use in chemical, pharmaceutical and other fields has gradually become important. The hardships of past exploration have become the cornerstone of current achievements, promoting the development of this compound in various industries, and the prospects are increasingly broad. In the future, there may be more wonderful discoveries, which will add to the well-being of mankind.
Product Overview
There is a compound named 1- [ (2-chloro-1,3-thiazole-5-yl) methyl] -2-methyl-3-nitroguanidine. This compound has unique properties and a wide range of uses. From its structural point of view, the chlorine atom is connected to the thiazolyl group, and there are clever combinations of methyl, nitro and other groups.
In the chemical industry, or as a key intermediate in the synthesis, assisting in the formation of other substances. In scientific research and exploration, it is a new selection of materials and opens an unknown chapter. The preparation method requires fine operation, and the reaction conditions of each step are strict, which is related to the purity and quantity of the product.
Although this object is small, it has great potential. If it is well researched and utilized, it will surely contribute to chemical industry and scientific research, create endless possibilities, and help development.
Physical & Chemical Properties
The physicochemical properties of 1- (2-chloro-1,3-thiazole-5-yl) methyl-2-methyl-3-nitroguanidine are of great importance to our research. Its physical properties, at room temperature or in a specific form, or in the state of crystallization, look at its color, or have a specific color. Regarding its solubility, in some solvents, it may be soluble or insoluble, which is related to its dispersion characteristics in different media.
Its chemical properties cannot be ignored. Contains chlorine, thiazole, nitro and other groups, these structures give it unique chemical activity. The presence of nitro groups may make the substance oxidizing to a certain extent; the characteristics of thiazole ring affect its selectivity in reaction with other substances. And under different conditions, specific chemical reactions may occur and participate in various chemical processes, which have a profound impact on its subsequent application and performance. We should investigate in detail to understand the mysteries of its physicochemical properties.
Technical Specifications & Labeling
There is now a product named 1 - [ (2 - chloro - 1,3 - thiazole - 5 - yl) methyl] - 2 - methyl - 3 - nitroguanidine. Its process specifications and identification (product parameters) are related to the manufacturing essence and identification of this product.
The process specifications are the method of preparing this product. From the selection of raw materials to the order of steps, there are rules. The raw materials must be pure, and the steps should be careful, so that a good product can be obtained.
The identification (product parameters) is a sign of the characteristics of this product. Such as its shape, its quality and its properties are clearly indicated. So that the viewer can see its appearance at a glance, and the user can make good use of it.
When manufacturing this product, strictly abide by the process specifications and clearly identify (product parameters) to ensure its quality and meet all needs.
Preparation Method
The method of preparing 1- [ (2-chloro-1,3-thiazole-5-yl) methyl] -2-methyl-3-nitroguanidine is related to the raw materials and production process, reaction steps and catalytic mechanism.
First take an appropriate amount of 2-chloro-1,3-thiazole-5-formaldehyde as the starting material, add a specific organic solvent, such as dichloromethane, in a suitable reaction vessel, and stir well. Then slowly add guanidine reactants containing methyl and nitro groups, and add an appropriate amount of basic catalysts, such as potassium carbonate, to promote the reaction.
The temperature is controlled in a certain range, about 40 to 50 degrees Celsius, and the reaction is sufficient when stirred continuously. After the reaction is completed, the product is purified by conventional separation methods, such as extraction and distillation. During this process, the proportion of raw materials, reaction temperature and time are precisely controlled to ensure that the reaction is efficient and the product is pure, so as to achieve the purpose of high-quality production.
Chemical Reactions & Modifications
The chemical reaction and modification of this compound of Fu 1- (2-chloro-1,3-thiazole-5-yl) methyl-2-methyl-3-nitroguanidine are related to the gist of chemical research.
At the end of the chemical reaction, during the synthesis process, the reactants meet and undergo chemical changes, according to a specific mechanism, to obtain this compound. However, this process, or under severe reaction conditions, temperature, pressure, catalyst, etc., has a slight difference, which will affect the yield and purity.
Discuss modification, in order to make it have better properties, or change its structure. Or introduce new groups and adjust their physical and chemical properties by chemical means to suit different applications.
In the field of chemistry, explore the reaction and modification of this compound, such as seeking secrets, gaining new knowledge, exploring new fields for chemical applications, and enabling this compound to develop its talents in various fields.
Synonyms & Product Names
There is now a thing named 1 - [ (2 - chloro - 1,3 - thiazole - 5 - yl) methyl] -2 - methyl - 3 - nitroguanidine. This thing plays an important role in our chemical research.
To find its synonymous name, there are also other names. Its synonymous name, or according to its structural characteristics, or according to its function and utility, is determined by academic research. As for the name of the product, merchants consider various factors such as the market and the audience, and give it a unique title, hoping to attract attention in the market and be easily remembered by the public.
This 1 - [ (2-chloro-1,3-thiazole-5-yl) methyl] -2-methyl-3-nitroguanidine, although the synonymous names and trade names are different, its essence is the same. All refer to this specific chemical substance, which exerts its inherent capabilities in the fields of research, production and application.
Safety & Operational Standards
1 - [ (2-chloro-1,3-thiazole-5-yl) methyl] - 2-methyl-3-nitroguanidine safety and operating specifications
Fu 1 - [ (2-chloro-1,3-thiazole-5-yl) methyl] - 2-methyl-3-nitroguanidine, an important substance for chemical research. In its research and application, safety and operating standards are of paramount importance.
The first word is safety. This substance has specific chemical properties or is potentially dangerous. When touching, be cautious. If it is directly in contact with the skin, it may cause irritation or even damage to the skin. Therefore, in the operation room, complete protective clothing, such as laboratory clothes, gloves, etc. must be worn to prevent it from touching the body. If it is accidentally touched, rinse with plenty of water immediately, and seek medical treatment if necessary.
As for inhalation, its volatile substances may enter the respiratory tract, harming the lungs. It is appropriate to operate in a well-ventilated place, or with the help of ventilation equipment, so that harmful gases can dissipate quickly. If you feel uncomfortable breathing, you should leave the scene quickly and go to a place with fresh air, and seek medical attention as appropriate.
Furthermore, the operation specification. When taking this substance, use a precise measuring tool, and take an appropriate amount according to the needs of the experiment. Do not increase or decrease at will, so as not to affect the experimental results or cause accidents. When weighing, the action should be slow to prevent it from spilling.
When mixing and blending, the specific order and method must also be followed. Read the relevant instructions carefully, follow the steps step by step, and avoid panic. The stirring action should be gentle and uniform, so that the mixture is uniform.
The method of storage should not be underestimated. It should be placed in a dry, cool and ventilated place, away from fire and heat sources. It should be placed separately from other chemical substances to avoid their mutual reaction.
All these safety and operating standards are to ensure the smooth research and protect the well-being of personnel. Those who engage in the research of this substance must keep it in mind and not slack off.
Application Area
Recently, in the study of chemical products, I have obtained a product named 1- [ (2-chloro-1,3-thiazole-5-yl) methyl] -2-methyl-3-nitroguanidine. The application field of this product is very wide.
In the domain of agricultural planting, it can be used as a pesticide, to protect seedlings and insects, and to protect the prosperity of crops. When pests encounter it, it is difficult to escape its effect, and it is also a help for farmers. And in the field of medicine, it can also be used. Or to help research new drugs to treat human diseases. Its nature may be able to attack pathogens, making it a healthy health.
In the field of materials, it is also possible. Or make the material heterogeneous and increase its use. Although this thing is new, it can be used in multiple fields, such as the shining of stars. It can be expected that its light will become more prosperous, used by the world, and beneficial to everyone.
Research & Development
In recent years, I have been focusing on the research of chemical products, focusing on 1 - [ (2-chloro-1,3-thiazole-5-yl) methyl] - 2-methyl-3-nitroguanidine. Its unique nature and wide application are promising in the field of agrochemical medicine.
During the research, we strive to clarify its structural characteristics and observe the reaction mechanism in detail. After various experiments, we know that the synthesis method can be used to obtain a pure product through a specific path. And under different conditions, looking at its changes, we know that temperature, humidity, and the proportion of reactants all affect its yield and quality.
Looking to the future, I hope to expand its application. In agriculture, it may become an efficient and low-toxicity pesticide to protect crops from diseases and pests; in medicine, or to assist in the development of new drugs and treat various diseases. I will do my best to promote the development of this product, add new colors to the industry, and benefit the world.
Toxicity Research
Toxicity studies
Recently, we have investigated the toxicity of 1- [ (2-chloro-1,3-thiazole-5-yl) methyl] -2-methyl-3-nitroguanidine in detail. This compound has been widely used in various fields, but its toxicity to biological effects is still lacking.
We took a variety of biological samples and applied it at different concentrations of this compound. After observation, it was found that at low concentrations, some biological physiology was slightly abnormal and the action was slightly slower. At high concentrations, biological damage was intensified, growth was stunted, and some died. At the cellular level, cell structure and function were destroyed, and metabolism was disordered.
From this point of view, 1- [ (2-chloro-1,3-thiazole-5-yl) methyl] -2-methyl-3-nitroguanidine has certain toxicity. In subsequent applications, it is necessary to be cautious and carefully study the safe dose to avoid unbearable ecological and biological consequences.
Future Prospects
In the future, in the research and development of our chemical industry, 1 - [ (2-chloro-1,3-thiazole-5-yl) methyl] - 2-methyl-3-nitroguanidine is not the future. It may be in the field of development, with the help of specialization, improve the efficiency and reduce the environment. And it can be derived to obtain new compounds, expand the territory of research, and cure diseases. It is also expected to develop special properties and new materials in the field of materials. Therefore, the possibility of this compound is limited. After our in-depth investigation, we will explore the new environment, hope to benefit the world, and promote the progress of chemical technology.
Frequently Asked Questions
What is the main use of 1- [ (2-chloro-1,3-thiazole-5-yl) methyl] -2-methyl-3-nitroguanidine
The main use of 1- [ (2-deuterium-1,3-butadiene-5-yl) ethyl] -2-ethyl-3-furan derivatives is related to applications in many fields.
In the field of organic synthesis, it often acts as a key intermediate. This compound has a unique chemical structure and can build complex organic molecular structures through various chemical reactions, such as nucleophilic substitution and addition reactions. Taking the construction of bioactive natural product analogs as an example, this derivative can be used as a starting material to gradually build a carbon skeleton of the target molecule through multi-step reactions, providing a possible lead compound for drug development.
In the field of materials science, it also has significant uses. Because its structure imparts certain physical and chemical properties, it can participate in the preparation of functional materials. For example, in photoelectric materials, after appropriate modification, the optical properties of the material may be improved, such as luminous efficiency, light absorption range, etc., and then applied to organic Light Emitting Diode (OLED), solar cells and other devices to improve the performance of such devices.
In the fragrance industry, this derivative may produce special aroma characteristics due to its unique chemical structure. After formulation and research and development, it may become an ingredient of new fragrances, adding novel aroma categories to the fragrance market and meeting consumers' needs for unique fragrances.
In summary, 1- [ (2-deuterium-1,3-butadiene-5-yl) ethyl] -2-ethyl-3-furan derivatives have shown important application value in organic synthesis, materials science, fragrance industry and other fields due to their special chemical structure, providing new opportunities and possibilities for the development of many fields.
What are the physical properties of 1- [ (2-chloro-1,3-thiazole-5-yl) methyl] -2-methyl-3-nitroguanidine
The physical properties of 1 - [ (2 - deuterium - 1,3 - tritium - 5 - yl) ethyl] - 2 - ethyl - 3 - carbonyl derivatives are as follows:
In this compound, deuterium and tritium are isotopes of hydrogen. Deuterium contains one proton and one neutron, with a mass number of two; tritium contains one proton and two neutrons, with a mass number of three. Due to isotopic substitution, molecular mass and density are affected. Generally speaking, compounds containing deuterium and tritium have a higher mass than those containing ordinary hydrogen, resulting in a corresponding increase in density.
In terms of chemical properties, the bond energy of carbon-deuterium bonds and carbon-tritium bonds is slightly higher than that of carbon-hydrogen bonds. This difference is reflected in the rate of chemical reactions, especially those involving the transfer of hydrogen atoms. The reaction rate of compounds containing deuterium and tritium is often slower than that of those containing ordinary hydrogen, which is the kinetic isotope effect.
2-ethyl moiety, as a common alkyl group in organic compounds, has a certain electron-giving effect. It can increase the electron cloud density of the atoms or groups connected to it, which affects the chemical activity and reaction check point selectivity of the compound.
3-carbonyl is a polar functional group. The oxygen atom of the carbon-oxygen double bond has strong electronegativity, which makes the carbonyl carbon partially positively charged and vulnerable to nucleophilic attack. In chemical reactions, carbonyl can undergo various reactions, such as nucleophilic addition, reduction, etc.
In terms of physical state, if the compound is not affected by other special functional groups, in view of the carbon chain length and functional group properties in its structure, it may be in a liquid state at room temperature and pressure. The existence of carbonyl groups makes it possible to form weak dipole-dipole interactions between molecules, which affects its boiling point and melting point. Compared with non-polar compounds, the boiling point may be increased. In terms of solubility, due to the fact that the molecule contains a polar carbonyl group and a certain length of carbon chain, it may have a certain solubility in polar organic solvents such as alcohols and ketones, while it may have limited solubility in non-polar solvents such as alkanes.
Is the chemical properties of 1- [ (2-chloro-1,3-thiazole-5-yl) methyl] -2-methyl-3-nitroguanidine stable?
The stability of the chemical substances inquired by the observer is related to the structural characteristics of (2-cyano- 1,3-butadiene-5-yl) ethyl, ethyl and allyl.
If the cyanogroup (2-cyano- 1,3-butadiene-5-yl) ethyl group has strong electron-absorbing properties in its structure, which can change the electron cloud density distribution of the carbon chain connected to it. And the structure of 1,3-butadiene is conjugated, which endows the system with certain stability. However, the electron-absorbing action of cyanogroup may reduce the electron cloud density of adjacent carbon sites, which affects the stability of the group to a certain extent. In case of electrophilic reagents, the check point where the electron cloud density decreases is vulnerable to attack and causes structural changes.
As for ethyl, the structure is relatively simple and only composed of hydrocarbon single bonds. The hydrocarbon single bond energy is relatively stable, and there is no obvious electron-absorbing or electron-donating group interference, so ethyl is relatively stable under general conditions, and is not prone to spontaneous chemical changes. It is often used as a stable component of organic structures.
Allyl has special chemical properties due to the presence of allyl rearrangement. Its π electrons can be delocalized, and when a reaction occurs, the allyl carbocation positive ion can be stabilized through the resonant structure. However, this structure also makes allyl more active under specific conditions. For example, in nucleophilic substitution and other reactions, the carbon-carbon double bond of allyl can participate in the reaction and change the original structure, so the stability is slightly weaker than that of ethyl.
To sum up, among the three, ethyl has higher stability, simple structure and stable chemical bonds; (2-cyano- 1,3-butadiene-5-yl) ethyl cyanide interacts with the conjugated structure, and the stability is second; the special electronic delocalization and rearrangement characteristics of allyl genes make the stability relatively weak.
What are the precautions for 1- [ (2-chloro-1,3-thiazole-5-yl) methyl] -2-methyl-3-nitroguanidine in the production process?
In chemical synthesis, (2-cyanogen-1,3-butadiene-5-yl) methyl, 2-methyl, and 3-furan derivatives do have many key points to pay attention to in the production process.
First of all, there must be no difference in the order and proportion of materials. (2-cyanogen-1,3-butadiene-5-yl) methyl, 2-methyl, and 3-furan derivatives have different chemical activities. If the order of delivery is disordered or the proportion is not correct, it is very likely that the reaction will not proceed according to the expected path, or the reaction rate will be abnormal, and even side reactions will be triggered, which will greatly affect the purity and yield of the product. If there were workshops in the past, due to mistakenly doubling the amount of 2-methyl input, the final product will be overgrown with impurities, and the expected quality will not be achieved at all.
Secondly, the precise regulation of reaction temperature and pressure is crucial. The reaction involving these three substances is extremely sensitive to temperature and pressure. If the temperature is too high, the reaction may be out of control, which will not only easily cause the product to decompose, but also cause safety accidents; if the temperature is too low, the reaction will be delayed or even stagnant. The same is true for pressure, or the reaction equilibrium will be offset In the past, there was a workshop. Due to the failure of the temperature control device, the reaction temperature rose sharply, which was dangerous, and the product was also destroyed.
Furthermore, the reaction time cannot be ignored. If it is too short, the reaction will not be completed, and the amount of product will be small; if it is too long, many side reactions may be derived, and the quality of the product will decrease. According to the reaction process, the reaction time must be precisely controlled by suitable monitoring means to achieve the best production effect.
Finally, the cleanliness of the reaction environment should not be underestimated. Impurities are mixed in, which may block the reaction or cause poisoning of the catalyst. Therefore, the reaction equipment must be clean, and the reaction environment needs to be strictly controlled to prevent impurities from interfering with the normal progress of the reaction.
What are the effects of 1- [ (2-chloro-1,3-thiazole-5-yl) methyl] -2-methyl-3-nitroguanidine on the environment?
The influence of 1 - [ (2-alkane-1,3-aldehyde-5-yl) ethyl] -2-ethyl-3-alkynyl group on the environment needs to be investigated in detail in the field of chemistry. In the era of "Tiangong Kaiwu", although there is no fine chemical analysis method today, it can be briefly analyzed at that time.
Looking at this chemical structure, the structure of (2-alkane-1,3-aldehyde-5-yl) ethyl group may have a complex effect on the surrounding environment due to the stability of alkane and the active characteristics of aldehyde. The alkyl group itself is relatively stable and difficult to react in the natural environment, but it can be used as a structural support to affect the physical properties of the whole molecule, such as solubility and volatility. The aldehyde group is much more active and is easy to react with many substances in the environment, such as oxidation and addition. In the environment, it may participate in atmospheric photochemical reactions, affecting air quality; in the water body, or react with substances dissolved in water, changing the chemical properties of the water body.
2-ethyl is used as a common alkyl group to increase the hydrophobicity of the molecule. In the environment, this property may make the substance enriched in the water-oil interface, biofilm and other regions. Its existence affects the interaction between molecules and different media in the environment, and then affects the migration and transformation of substances in the environment.
3-alkynyl groups are highly unsaturated and have extremely active chemical properties. In the environment, alkynyl groups are prone to addition reactions with electrophilic reagents, and can participate in chemical reactions on the surface of some minerals in the soil, changing the chemical composition and properties of the soil. In organisms, they may react with biological macromolecules such as proteins and nucleic acids, interfering with the normal physiological functions of organisms.
In conclusion, the characteristics of each group of the 1 - [ (2-alkane-1,3-aldehyde-5-yl) ethyl] -2-ethyl-3-alkyne gene have various effects on the environment through physical, chemical and biological processes in different environmental media, which need to be carefully studied and considered.