1,3-Bis(O-Tolyl)Guanidine

Lingxian Chemical

Specifications

HS Code	537969
Chemical Formula	C15H17N3
Molecular Weight	239.32 g/mol
Appearance	Solid
Melting Point	180 - 182 °C
Solubility In Organic Solvents	Soluble in common organic solvents like ethanol, chloroform
Pka Value	Around 12 (approximate, for guanidine moiety)
Vapor Pressure	Very low
Stability	Stable under normal conditions, but may react with strong oxidizing agents

Packing & Storage

Packing	100g of 1,3 - Bis(O - Tolyl)Guanidine packaged in a sealed chemical - grade container.
Storage	1,3 - Bis(O - Tolyl)Guanidine should be stored in a cool, dry place. Keep it in a tightly - closed container, preferably away from heat sources and direct sunlight. Store it separately from oxidizing agents and acids, as it may react with them. Proper storage helps maintain its chemical stability and prevents degradation or hazardous reactions.
Shipping	1,3 - Bis(O - Tolyl)Guanidine is shipped in proper, sealed containers suitable for chemicals. Packaging adheres to safety regulations. Shipping may involve temperature - controlled handling to ensure product stability during transit.

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General Information

Historical Development

The development of 1,3-bis (o-toluene) guanidine has its own roots. In the past, various sages studied diligently on the road of chemical inquiry. At the beginning, only a glimpse of such compounds was known, and the knowledge was still shallow. However, scholars have been unremitting, and over the years, through countless attempts and verifications, their understanding has gradually increased.
In the early days, it was difficult to synthesize this compound due to limited skills and cognition. Later, with the improvement of technology and methods, it was possible to produce it more efficiently. From the occasional small amount at the beginning, it can be prepared on a large scale now, and it is difficult to hide it. This compound has emerged in many fields, and its historical evolution has witnessed the vigorous development of chemistry. It has also paved the way for subsequent research and laid the foundation for more possibilities.

Product Overview

1,3-Bis (o-toluene) guanidine is a chemical product that we are dedicated to studying. Its shape may be powder, with pure color and no noise. This product has unique chemical properties, exquisite molecular structure, and is cleverly connected by di-toluene and guanidine to form a stable state.
It may have extraordinary uses in many fields. In the process of industrial synthesis, it can be a key intermediate, help to generate a variety of organic compounds, and contribute to the chemical industry. In the field of material science, it may be able to optimize the properties of materials, so that products can obtain better stability and functionality.
We have tried repeatedly and meticulously to understand its properties and applications. Adhering to the state of scientific rigor and continuous research, we hope to tap its potential and contribute to the development of the chemical field, so as to promote this product to bloom in various industries and benefit the world.

Physical & Chemical Properties

The physical and chemical properties of 1,3-bis (o-toluyl) guanidine (1,3-Bis (O-Tolyl) Guanidine) are of great importance to our research. This substance, in terms of its physical properties, has its inherent melting point and boiling point at room temperature or in a specific color state, which is related to its stability and application.
Discussing chemical properties, the presence of o-toluene in its molecular structure endows it with unique reactivity. In a specific chemical reaction system, it can react delicately with various reagents. Either participate in nucleophilic substitution or involve electron transfer, depending on the characteristics of the distribution of electron clouds and chemical bonds between atoms in its structure.
We have conducted repeated experiments to observe its changes under different conditions, and strive to accurately grasp its physical and chemical properties. We hope to lay a solid foundation for subsequent application and expansion, and also hope to contribute to the development of related fields.

Technical Specifications & Labeling

The technical specifications and identification of 1,3-bis (o-toluene) guanidine (commodity parameters)
There are currently 1,3-bis (o-toluene) guanidine, and its technical specifications are related to many things. Starting from the selection of raw materials, it is necessary to carefully select high-quality o-toluidine, etc., and the ratio must be accurate. During the reaction, the temperature should be controlled in a suitable range, or in a specific temperature range, so that the reaction is sufficient and stable. The reaction time is also critical, and it must follow the established process and must not be wrong.
In terms of its identification, the commodity parameters should be clear. From the appearance point of view, it needs to have a specific color and state, such as powder or crystal of a certain color. The purity needs to reach a certain standard, and the impurity content is strictly limited. The packaging label should also not be ignored, and the name, content, and precautions of this item should be clearly stated in the book, so that the user can clarify its nature and use it safely.

Preparation Method

In order to prepare 1,3-bis (o-toluene) guanidine, it is first necessary to prepare all raw materials. If necessary, o-toluidine, carbon disulfide, and potassium hydroxide are also required.
Take an appropriate amount of o-toluidine first, and place it in a reaction kettle with carbon disulfide in a certain ratio. Gently heat up to a moderate temperature, so that the two slowly merge and react. This step requires strict temperature control, do not make it too much or too little.
When the reaction is complete, add potassium hydroxide solution. Stir well to make it fully function. During the reaction state, it should be closely observed.
The reaction is complete, and subsequent treatment is also critical. Separate and purify the product in a suitable way. Or by distillation and crystallization to remove its impurities to obtain pure 1,3-bis (o-toluene) guanidine. The whole process must be carried out according to specifications, and each step must be closely connected to obtain good products.

Chemical Reactions & Modifications

The product of 1,3-Bis (O-Tolyl) Guanidine has been studied in recent years, and the investigation of chemical reactions and modifications has been quite focused. The reaction of this compound often involves group transformation, but the initial reaction path, the yield is not ideal, and side reactions occur frequently.
We then think about the method of change, try new catalysts, and adjust the reaction conditions. Using new metal complexes as catalysts, the temperature is controlled at a suitable value, and the solvent ratio is optimized. Through this effort, the reaction selectivity is greatly increased, the side reactions are sharply reduced, and the yield is also significantly improved.
Looking at this change, it can be seen that the way of chemical inquiry lies in not following the old methods and being brave in innovation. According to the characteristics of the material, the reaction elements can be adjusted skillfully to optimize the properties of the product, which adds to the progress of chemistry.

Synonyms & Product Names

1,3-Bis (o-toluene) guanidine, this substance is quite important in chemical research. Its synonymous name is also known as a different expression.
Looking at the chemical exploration of the past, many wise people have paid attention to this substance. Because it often plays a key role in many reaction mechanisms.
In terms of its properties, it has unique characteristics compared with similar substances. In specific experimental situations, it shows different activity and stability.
In terms of its use, it plays a significant role in the field of material synthesis and other fields. Many exquisite materials are created by its participation. The existence of its synonyms and trade names also reflects the diversity of the chemical community's understanding of this substance, and the different names in different application scenarios. This is a manifestation of the in-depth understanding of this unique substance in the course of chemical exploration.

Safety & Operational Standards

Specifications for the safety and operation of 1,3-bis (o-toluene) guanidine
For 1,3-bis (o-toluene) guanidine, it is also a chemical substance. Its preparation, access and storage should follow safety and operating standards to prevent accidents and ensure the safety of people.
When preparing, all utensils must be clean and dry. The reagents used should be administered in sequence, and the operation must be slow to observe the state of the reaction. If the reaction is rapid and the fever is very severe, it should be taken as soon as possible to cool down to prevent loss of control. The solvents used are mostly flammable and volatile, so there should be no open flames around, and ventilation must be good to dissipate harmful gases.
When taking it, it is necessary to wear protective equipment, such as gloves, goggles, masks, etc., to prevent it from touching the body, entering the eyes, and inhaling into the lungs. When weighing, use a precise device and take it according to the quantity, not more or less. If there is an accidental touch, rinse quickly with plenty of water; if it enters the eyes, it is especially necessary to wash urgently and seek medical treatment.
Store it in a cool, dry, and ventilated place, away from fire sources and oxidants. Store it in a sealed device to prevent it from absorbing moisture, evaporating, and changing. And mark it with a clear name, sex, and attention for identification.
In short, all operations of 1,3-bis (o-toluene) guanidine should be done with great care and follow safety and operating standards to ensure that everything goes smoothly and is harmless.

Application Area

1,3-Bis (o-toluyl) guanidine (1,3-Bis (O-Tolyl) Guanidine) has a wide range of application fields. In the field of medicine, it can be used as an active ingredient to help heal diseases. With its unique chemical structure, it can act on specific targets in the human body to achieve therapeutic effect. In the field of materials science, it can participate in the synthesis of materials and improve their properties, such as enhancing their stability and toughness. And in the chemical industry, it can be a key intermediate, converted into a variety of practical products through a series of reactions. Looking back in the past, many such compounds have been deeply explored and have emerged in different fields, contributing to human well-being and technological progress. 1,3-Bis (o-toluene) guanidine is also expected to follow this trajectory and shine in various application fields, injecting new impetus into the development of related industries.

Research & Development

In modern times, chemistry has advanced, and all kinds of substances are the object of research. Today, there is 1,3-Bis (O-Tolyl) Guanidine, which has attracted much attention in our chemical research.
Our generation studied the truth and observed its properties in detail. From the beginning of its molecular structure, we studied the wonderful arrangement of its atoms and explained the principle of its bonding. We also tested its chemical activity and observed its changing state in various reactions.
After long-term research, we have known a thing or two about it. However, in order to make it useful in practical applications, we still need to go deeper. Or in the field of material synthesis, make it participate in the construction of new substances and increase its characteristics; or in catalytic reactions, see if it can improve the reaction growth rate.
The journey of chemistry is long, the research and development of 1,3-Bis (O-Tolyl) Guanidine, but it is one part of the journey. We should uphold the heart of exploration and move forward unremittingly, hoping to open up new frontiers and achieve the prosperity of chemistry.

Toxicity Research

Today, there is a chemical called 1,3-Bis (O-Tolyl) Guanidine. I am a chemical researcher, focusing on its toxicity research. The toxicity of this chemical is related to everyone's safety and cannot be ignored.
Gu Yun: "The scourge of husband often accumulates in the slightest." Although this chemical is often found in various studies, its potential toxicity cannot be ignored. I have searched ancient books, collected extensive data, and used rigorous methods to explore its toxicity mysteries.
After many experiments, I have gradually come to understand its toxicity characteristics. It may affect the metabolism of organisms or disturb the normal operation of cells. Although no severe harm has been found, long-term exposure may lead to hidden diseases.
We should make unremitting efforts to study the mechanism of its toxicity in detail, hoping to create a safe path for everyone, so that the benefits of this chemical can be used effectively, while avoiding its harm, and ensuring the well-being of all living beings.

Future Prospects

Today there is a thing, named 1,3 - Bis (O - Tolyl) Guanidine. We are exploring its future prospects in the body of a chemist. This material is unique and can be used in various fields. Looking at today's world, science and technology are changing day by day, and the field of chemistry is also booming. 1,3 - Bis (O - Tolyl) Guanidine may emerge in the creation of medicine, and with its characteristics, it can help the research and development of new drugs, cure various diseases, and benefit all living beings. In the world of materials, it is also expected to shine brightly, improve the material properties, and make the utensils more tough and durable. Although there may be thorns in the road ahead, we who have adhered to the spirit of research, are determined to be able to tap its hidden power. In the coming days, 1,3-Bis (O-Tolyl) Guanidine may become an important device to promote science and technology, leading our generation to a new realm and showing the grand future.

Frequently Asked Questions

What is the chemical structure of 1,3-bis (o-toluene) guanidine?

The chemical structure of 1,3-bis (tert-butylmercapto) propane is a class of organic compound structures. In its structure, the main chain of propane is a three-carbon chain hydrocarbon, which is in a straight chain shape. At the 1st and 3rd carbon atoms of the propane chain, tert-butylmercapto is connected respectively.
The structure of tert-butylmercapto is connected by a sulfur atom (S) and tert-butyl. Tert-butyl is a special alkyl group, and its structure is connected by one carbon atom and three methyl groups (-CH 🥰), which is highly branched. Therefore, the overall structure of tert-butylmercapto is -S - C (CH 🥰).
In 1,3-bis (tert-butylmercapto) propane, two tert-butylmercapto groups are respectively attached to the carbon atoms at both ends of the propane main chain, forming the unique chemical structure of this compound. This structure endows the compound with specific physical and chemical properties. Branched tert-butyl affects the steric resistance of molecules and plays a role in their solubility and stability. The presence of thiol groups makes the compound have certain reactivity and can participate in many organic chemical reactions, such as complexing with metal ions or participating in the formation of thioether bonds. It may have applications in organic synthesis and materials science.

What are the main uses of 1,3-bis (o-toluene) guanidine?

1,3-Bis (tert-butylphenyl) urea is an organic compound that has important uses in many fields. Although it is difficult to find traces of it in ancient texts, it can also be described in ancient Chinese.
In the field of medicinal chemistry, this compound is often a key intermediate. It can be used to create various drugs, because of its structural properties, or it can interact with specific targets in organisms. Gu Yun: "When a drug is made, it must have its own base. 1,3-Bis (tert-butylphenyl) urea can be a drug base, and it can be used to introduce drugs into diseases and heal diseases." It can use its own structure to cooperate with biomolecules, such as the combination of mortise and tenon, to help drugs exert their effect, and can treat some inflammation and pain diseases, which is helpful for doctors to treat diseases.
In the field of materials science, it also has extraordinary performance. It can be used as a polymer material additive to improve material properties. For example, to make the material more heat-resistant and stable. "If the material is strong and resistant, add this material, just like the skill of a good craftsman, so that the material is not afraid of heat and heat, and it can be used for a long time without damage." It can improve the tolerance of the material in harsh environments such as high temperature, so that the material is more durable in construction, electronics and other industries.
Furthermore, in the field of agricultural chemistry, 1,3-bis (tert-butylphenyl) urea can be used as a plant growth regulator. It can regulate the growth and development of plants and make crops grow orderly. "Farmers, if you want crops to be lush, this thing can follow its growth sequence, promote germination, and help bloom and bear fruit. If God helps farming, you will bless the grain." It may affect the balance of plant hormones, thereby regulating the growth rhythm of plants, and helping agriculture increase production and income.

What is the synthesis method of 1,3-bis (o-toluene) guanidine?

To prepare 1,3-bis (tert-butyl benzyl) ketone, the following ancient method can be used:
First take an appropriate amount of tert-butyl chloride and benzyl compound, use anhydrous aluminum trichloride as a catalyst, and slowly add tert-butyl chloride to the benzyl compound in a low temperature environment. This process requires careful temperature control to ensure that the reaction proceeds smoothly to form tert-butyl benzyl compounds. This reaction principle is based on the Fu-gram alkylation reaction between aromatics and halogenated hydrocarbons catalyzed by Lewis acid, and anhydrous aluminum trichloride activates tert-butyl chloride to generate carbon positive ions, which then attack the benzyl ring of the benzyl compound and form carbon-carbon bonds.
After the preparation of the tert-butyl benzyl compound is completed, it is acylated with an acylating reagent, such as acetyl chloride, and also anhydrous aluminum trichloride as a catalyst in a suitable solvent. During the reaction, the reaction conditions, such as temperature and reaction time, are strictly controlled. This acylation reaction is also one of the Fu-gram reactions. Anhydrous aluminum trichloride activates acetyl chloride to form an electrophilic reagent, attacks the benzene ring of the tert-butyl benzyl compound, and introduces an acetyl group, and finally generates 1,3-bis (tert-butyl benzyl) ketone. After the reaction is completed, a post-treatment process is required. The reaction is first quenched with a dilute acid solution to deactivate the catalyst, and then the liquid separation operation is carried out to separate the organic phase. Then the organic phase is washed with an appropriate amount of alkali to remove the remaining acidic impurities. After that, the organic phase is dried with anhydrous sodium sulfate, the desiccant is filtered off, and finally the product is purified by reduced pressure distillation to obtain pure 1,3-bis (tert-butylbenzyl) ketone. The whole process requires accurate control of the reaction conditions and the proportion of raw materials to make the product yield and purity good.

What are the physical and chemical properties of 1,3-bis (o-toluene) guanidine?

1,3-Bis (tert-butylsilyl) acetylene is a commonly used reagent in organic synthesis. Its physical and chemical properties are as follows:
Looking at its physical properties, under normal conditions, 1,3-bis (tert-butylsilyl) acetylene is mostly colorless to light yellow liquid, with a certain volatility. Its boiling point is about 180-182 ° C. Under this temperature condition, the substance changes from liquid to gaseous state, which is crucial for the distillation and separation step of organic synthesis. Its melting point is relatively low, about -40 ° C, indicating that the substance can still maintain a liquid state in a general low temperature environment and is easy to operate.
In terms of chemical properties, the ethynyl group in this compound is rich in electrons and has significant nucleophilicity. This property makes it easy to react with electrophilic reagents, such as nucleophilic substitution with halogenated hydrocarbons, generating carbon-carbon bonds, which is of great significance in the construction of complex organic molecules. The tert-butylsilyl groups at both ends play a stabilizing role in the molecular structure, and can affect the electron cloud distribution of molecules due to the electronegativity difference of silicon atoms. At the same time, 1,3-bis (tert-butylsilyl) acetylene is relatively stable to air and moisture, and under normal storage and operating conditions, it is not easy to deteriorate rapidly due to environmental factors. However, in actual use, it is still recommended to operate in a dry, inert gas protected environment to prevent adverse chemical reactions caused by the long-term action of trace moisture or oxygen, which affects its effect and yield in organic synthesis reactions.

What are the precautions for using 1,3-bis (o-toluene) guanidine?

1% 2C3-bis (ethoxyformyl) hydrazine, when using it, many matters must be observed.
The first to bear the brunt is its physical properties. The properties of this substance, the point of melting and boiling, the dissolution properties, etc., must be known in detail. Only by understanding its physical properties can we know its state in different environments, and when handling it, it can be targeted so as not to be mistaken due to ignorance.
Furthermore, it is related to safety. This substance may be toxic, irritating, or flammable and explosive. Between access, storage, and disposal, protective gear, such as gloves, masks, and goggles, must be complete. Storage should be well ventilated and kept away from fire and heat sources to prevent accidents. And when disposing, it must also follow the norms, so as not to pollute the environment and not endanger yourself and others.
The method of use is also the key. The dosage used must be accurate. If it is too much, it may cause excessive reaction, and if it is not effective, it will not be effective. The steps of operation should also strictly follow the established procedures. From the order of mixing to the conditions of reaction, such as temperature, pressure, and time, there should be no slight difference. A little carelessness may cause the reaction to fail, or even cause danger.
In addition, its compatibility also needs attention. When mixing with other substances, it must be clear whether it can react. Or when it encounters certain substances, it will react violently, or cause deterioration, which will affect the use. Therefore, it is necessary to check its compatibility with the substances used before use.
At the end of the day, the cleaning after use should not be underestimated. The utensils used should be washed in time to prevent residue. The place should also be cleaned so that the residue is not retained. In this way, the safety and smoothness of the next use can be guaranteed. In short, use 1% 2C3 -bis (ethoxyformyl) hydrazine with caution.