1,3-Bis(Tert-Butoxycarbonyl)Guanidine

1% 2C3-bis (tert-butoxycarbonyl) hydrazine is a commonly used reagent in organic synthesis. Its main uses are quite extensive, and it has significant functions in the field of organic synthesis.
One is often an amino protection reagent. In many organic reactions, the amino group is active and prone to side reactions. And 1% 2C3-bis (tert-butoxycarbonyl) hydrazine can interact with the amino group to protect it. After the reaction is completed, the protective group is removed under specific conditions, which can effectively prevent the amino group from participating in the side reaction for no reason during the reaction and ensure that the reaction proceeds in the expected direction.
Second, it is also a key raw material when constructing nitrogen-containing heterocyclic compounds. Nitrogen-containing heterocyclic structures are widely found in various drugs, natural products and functional materials. 1% 2C3-bis (tert-butoxycarbonyl) hydrazine can participate in a series of cyclization reactions by virtue of its special structure, which facilitates the construction of nitrogen-containing heterocyclic rings. Through ingenious design of reaction paths, nitrogen-containing heterocyclic compounds with specific structures and functions can be precisely synthesized, which is of great significance in drug research and development and other fields.
Third, it is also used in the field of polypeptide synthesis. The synthesis process of polypeptides is complex, and the connection and protection requirements of each amino acid residue are strict. 1% 2C3-bis (tert-butoxycarbonyl) hydrazine can protect the amino groups above amino acids, help polypeptides to connect correctly in a predetermined order, improve the yield and purity of peptide synthesis, and promote the development of peptide chemistry.

1,3-Bis (tert-butyloxy) hydrazine is an important chemical substance in organic synthesis. Its chemical properties are unique and it plays a key role in many chemical reactions.
One of them has significant reducing properties. This property makes it often appear in reduction reactions, and can reduce some oxygen-containing compounds, such as carbonyl compounds, to corresponding alcohols. Taking aldose and ketone as an example, 1,3-bis (t-butyloxy) hydrazine can use its own reducing properties to promote the addition of carbonyl groups in aldehyde and ketone molecules to hydrogen atoms, convert them into hydroxyl groups, and then generate alcohols. This reaction mechanism is based on the reactive group contained in its molecular structure, which can undergo specific electron transfer and chemical bond recombination with carbonyl groups.
Its di1,3-bis (tert-butyloxy) hydrazine can be used as a nucleophilic reagent in some reaction systems. Its molecular structure gives it a certain nucleophilic ability and can launch a nucleophilic attack on electrophilic reagents. In the field of organic synthesis, nucleophilic substitution reactions are one of the common types of reactions. 1,3-bis (tert-butyloxy) hydrazine can attack the carbon atoms of electrophilic substrates such as halogenated hydrocarbons by virtue of its nucleophilicity, forming new carbon-nitrogen or carbon-oxygen chemical bonds, thereby constructing more complex organic molecular structures.
Furthermore, this substance may undergo decomposition reactions at high temperatures or under specific catalytic conditions. The decomposition process often releases small molecules such as nitrogen, and other active intermediates are formed at the same time. This property can be used to construct specific ring structures or introduce specific functional groups in some special organic synthesis strategies. For example, in some intra-molecular cyclization reactions, the active intermediate produced by the decomposition of 1,3-bis (tert-butyloxy) hydrazine can promote the rearrangement and cyclization of chemical bonds in the molecule to synthesize organic compounds with a specific cyclic framework.
Because of the presence of a larger substituent tert-butyloxy in the molecule, it has a certain steric hindrance effect. This steric hindrance affects the selectivity and rate of the reaction in chemical reactions. When reacting with other molecules, the steric hindrance can make the reaction more inclined to a specific reaction check point, thereby improving the regioselectivity of the reaction and helping to synthesize targeted organic compounds.

The synthesis of 1% 2C3-bis (tert-butoxycarbonyl) hydrazine is an important issue in organic synthesis. To prepare this substance, the following method can be used:
Start with hydrazine as the starting material. Hydrazine has active chemical properties and is often the basis for the synthesis of many nitrogen-containing compounds. Take an appropriate amount of hydrazine and react with tert-butoxycarbonylation reagents. Tert-butoxycarbonylation reagents, such as di-tert-butyl dicarbonate ($Boc_2O $). This reaction needs to be carried out in a suitable reaction environment.
In the reaction system, a suitable base needs to be added to help the reaction. The function of a base is to adjust the pH of the reaction system and promote the reaction to proceed in the direction of generating the target product. Common bases, such as triethylamine, can effectively catalyze this reaction. The reaction temperature is also a key factor. Generally speaking, under low temperature conditions, the reaction is relatively mild, which can better control the reaction process and reduce the occurrence of side reactions. The reaction temperature is usually maintained between 0 ° C and room temperature.
During the reaction, the tert-butoxycarbonyl in di-tert-butyl dicarbonate will combine with the nitrogen atom in the hydrazine molecule. This process undergoes a series of complex chemical changes, such as nucleophilic substitution. As the reaction progresses, 1% 2C3-bis (tert-butoxycarbonyl) hydrazine is gradually formed.
After the reaction is completed, the product needs to be separated and purified. Various separation methods can be used, such as column chromatography. According to the difference in the partition coefficient between the product and the impurity between the stationary phase and the mobile phase, the effective separation of the product and the impurity can be achieved. After elution, concentration and other steps, a pure 1% 2C3 -bis (tert-butoxycarbonyl) hydrazine product can be obtained.
This synthesis method, although the steps seem complicated, can obtain high yield and purity of the target product by reasonably controlling the reaction conditions and selecting suitable reagents and operations, which has important practical value in the field of organic synthesis.

1% 2C3 -Bis (tert-butyloxycarbonyl) hydrazine is an important chemical substance. During storage and transportation, many precautions must be paid attention to.
First, when storing, be sure to choose a dry, cool and well-ventilated place. This is because if the substance is placed in a humid environment, it is susceptible to deliquescence, resulting in damage to its quality. For example, in the rainy season in the south, the air humidity is quite high, and if it is not stored properly, it is easy to change. And the temperature should not be too high, high temperature can easily cause it to decompose and cause danger.
Second, during transportation, the packaging must be strong and well sealed. To prevent leakage, if it leaks outside, it will not only pollute the environment, but also cause harm to those who come into contact. The packaging material should be corrosion-resistant and can resist the possible erosion of the substance. If it is packaged in a special corrosion-resistant plastic container or metal container, supplemented by a buffer material to prevent collision damage during transportation.
Third, whether it is stored or transported, keep away from fire sources and oxidants. This substance is dangerous to cause combustion and explosion in case of open flames, hot topics or contact with oxidants. If chemical transportation vehicles are running, they must not be close to fire sources such as gas stations, and must not be mixed with oxidant substances.
Fourth, relevant operators must undergo special training and strictly abide by the operating procedures. During storage management and transportation operations, wear appropriate protective equipment, such as protective gloves, protective glasses, etc., to ensure your own safety.
This way, the safety and stability of 1% 2C3-bis (tert-butyloxycarbonyl) hydrazine during storage and transportation can be ensured.

For 1% 2C3-bis (tert-butyloxycarbonyl) piperazine, the market price is probably not fixed, because there are many reasons to fluctuate its price.
First, the price of raw materials produced is different. Raw materials such as tert-butyloxycarbonyl may vary in price due to differences in weather, geopolitical conditions, and supply and demand conditions. If the production of raw materials decreases sharply and demand exceeds supply, the price will rise, causing the price of 1% 2C3-bis (tert-butyloxycarbonyl) piperazine to rise; conversely, if the supply of raw materials exceeds demand, the price may decrease, and the price of this product will also decrease.
Second, the complexity of the production process is related to the cost. If the process is complex, it requires exquisite design and high-tech work, and the cost of completion will be high and the price will be expensive; if the process is gradually simplified and the efficiency increases, the cost will decrease and the price will fall.
Third, the supply and demand state of the city is the main reason. In the fields of medicine, chemical industry, etc., if the demand for this product is greatly increased, but the production is difficult to respond quickly, the price will rise; if less is required and more is supplied, the price will automatically decline.
Fourth, the origin and the brand are also famous. Different origins, due to different taxes, transportation and other fees, the price is different; well-known brands, with their trust and quality, the price may be higher than usual.
Basically, the price of this product is in the market, and the price may range from tens to hundreds of yuan per gram. If you want to know the price, you must consult the supplier or the broker of the market in detail depending on the real-time market conditions, purchase quantity and transaction conditions.