1,3-Di-(2-Tolyl)Guanidine

Lingxian Chemical

Specifications

HS Code	412232
Chemical Formula	C15H17N3
Molecular Weight	239.32 g/mol
Appearance	Solid
Melting Point	180 - 182 °C
Solubility In Water	Insoluble
Solubility In Organic Solvents	Soluble in common organic solvents like dichloromethane, chloroform
Stability	Stable under normal conditions, but may react with strong oxidizing agents

Packing & Storage

Packing	500g of 1,3 - Di - (2 - Tolyl)Guanidine packaged in a sealed, labeled chemical - grade container.
Storage	1,3 - Di - (2 - Tolyl)Guanidine should be stored in a cool, dry space away from direct sunlight. It should be in a tightly - sealed container to prevent moisture and air exposure which could lead to degradation. Keep it separate from incompatible materials like strong oxidizers. Store in a well - ventilated area to minimize the risk of vapors concentrating. Ensure the storage area is locked if there are safety or regulatory requirements.
Shipping	1,3 - Di - (2 - Tolyl)Guanidine is shipped in well - sealed, corrosion - resistant containers. It follows strict safety regulations for chemical transport to ensure safe delivery, avoiding exposure to heat, moisture, and incompatible substances.

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General Information

Historical Development

The birth and evolution of 1,3-di- (2-toluenyl) guanidine is quite noteworthy. In the past, chemical research was just beginning, and all the sages devoted themselves to the exploration of new qualities. At that time, the understanding of organic structure gradually deepened, and the synthesis method became increasingly exquisite.
After years of research, the public finally obtained this 1,3-di- (2-toluenyl) guanidine with the technique of organic synthesis. At the beginning, the preparation was difficult and the yield was quite low, but the aspirations of scholars were not discouraged. With the passage of time, science and technology have advanced day by day, the synthesis process has been improved, the yield has gradually increased, and the quality has also improved. From the initial difficult creation to the current large-scale preparation, the development process of this compound reflects the scene of chemical research and development, and also paves the foundation for future generations to explore the road of chemistry.

Product Overview

1,3-Bis- (2-toluphenyl) guanidine is one of the substances I have encountered in the study of chemical products. Its characteristics are specific and have a unique structure. Looking at the shape of its molecule, bis (2-toluphenyl) is connected to guanidine, and the structure is exquisite. This product is often used as a key agent in the reaction, either to promote the speed of the reaction or to modify the product. It has a wide range of uses in the field of organic synthesis. With its unique properties, it can make various reactions occur according to our requirements and obtain the expected product. Although its name has not been widely spread to the public, it is a sharp weapon in the heart of my chemical researchers, helping us explore the mystery of chemistry, break the difficulty of synthesis, and hope to use it as a foundation to explore more new paths and create more wonders in the future.

Physical & Chemical Properties

The physicochemical properties of 1,3-di- (2-toluene) guanidine are crucial. Looking at its physical properties, at room temperature, it often takes a specific form, or is a solid state, with specific color, taste and appearance characteristics. Its solubility also varies among various solvents. It is soluble in one type of solvent, but insoluble in others, which is related to its application.
When it comes to chemical properties, it has certain reactivity. Under specific reaction conditions, it can react with many chemical substances. For example, when it encounters a certain type of reagent, it can initiate a specific chemical reaction and generate new compounds. This reaction property lays an important foundation for its application in chemical synthesis and other fields, and also provides key clues and basis for our in-depth investigation of its properties and development of related applications.

Technical Specifications & Labeling

1,3-Di- (2-toluene) guanidine is a special chemical product. Its technical specifications and labels (commodity parameters) are related to the quality and use of this material.
Looking at its technical specifications, it is necessary to accurately measure the proportion of each ingredient, so that the purity is extremely accurate, and the impurity content is minimal. The production process must follow strict methods to control the temperature and pressure at an appropriate value, to ensure that the reaction is smooth, and to obtain the output of high-quality products.
As for the label, when the name, molecular formula and structural formula are stated, the chemical essence is known to the viewer. It is also necessary to specify the physical properties, such as color, state, taste, etc., and important chemical properties, such as stability and reactivity. In the product parameters, specifications, purity, packaging, etc. should be clear to help users choose and use them, so as to make good use of this product.

Preparation Method

There is a method for preparing 1, 3-di- (2-toluphenyl) guanidine, which is described in detail as follows. Prepare all raw materials first, and take an appropriate amount of 2-methylaniline, cyanamide, etc. The process of preparation begins with the condensation reaction of 2-methylaniline and cyanamide according to a specific ratio, at a suitable temperature and in the presence of a catalyst. Its temperature should be controlled within a certain range, and it must be appropriate at the time. After this reaction, the primary product is obtained.
Then, the primary product is purified by a suitable method. It can be purified by extraction, distillation, etc., to remove impurities and purify the product. In this purification process, every step must be careful to prevent the loss of the product or the re-entry of impurities.
The mechanism of its preparation is that the amino group in 2-methylaniline and the active part of cyanamide, with the help of the catalyst, form a bond with the phase to produce 1,3-di- (2-methylphenyl) guanidine. In this way, following these steps, the product can be obtained.

Chemical Reactions & Modifications

I will study the chemical reaction and modification of 1,3 - Di - (2 - Tolyl) Guanidine. In the field of chemistry, the reaction is specific, and the way of modification is also very interesting.
Looking at the reaction, under various conditions, there are many changes. Or combination with other things, or its own structural changes, are all related to the temperature, pressure, catalyst and other factors of the reaction. Reasonable adjustment can make different products.
As for modification, want to increase its certain properties, such as stability, activity and so on. After many explorations, or change its molecular structure, or add other groups, the performance has been improved.
For our chemical researchers, studying the reaction and modification of 1,3 - Di - (2 - Tolyl) Guanidine is like exploring the secrets. Every new acquisition is a joy. I hope this research can lead to chemical progress and be beneficial to the world.

Synonyms & Product Names

The substance 1,3-di- (2-toluene) guanidine is of great significance in the field of my chemical research. Its aliases and trade names are also key points for investigation. Looking at its aliases, they all revolve around its chemical structure and characteristics. The determination of the trade name may be related to factors such as the manufacturer and market positioning.
When we study this product, we need to clarify the relationship between its different titles. From an academic point of view, aliases can help us accurately grasp its chemical essence; from a commercial point of view, trade names affect its market circulation and application. Like ancient utensils, each has its own name, and the name is different or different, but the essence is the same. The aliases and trade names of 1,3-di- (2-methylphenyl) guanidine are also the same. Although the expressions are different, they actually refer to the same thing. They are all key markers for chemical research and application, guiding our generation to explore its properties, uses and potential values.

Safety & Operational Standards

1,3-Di- (2-methylphenyl) guanidine is crucial to its safety and operating standards.
This chemical substance has unique properties. When preparing, all raw materials, when accurately weighed, are mixed in a specific order and ratio. The reaction conditions must be strictly controlled, including temperature, pressure, slight poor pool, or abnormal reaction, impure product, or even dangerous.
In the operation room, safety protection is indispensable. All operators must wear protective clothing, goggles, and gloves to prevent this substance from touching the skin and eyes. If you accidentally touch it, rinse it with a lot of water quickly, and in severe cases, seek medical treatment.
When storing, place in a cool, dry place, away from fire and heat sources. This substance may have certain chemical activity, and when heated, wet, or changed, its performance may change, or it may pose a safety risk.
When taking it, use it in an accurate amount and seal it immediately. If it is placed at will, it may cause its properties to change, or pollute the surrounding environment.
Furthermore, the operating area must be well ventilated. The volatile gas of this substance may be harmful to the human body. Good ventilation can reduce the concentration of this substance in the air and ensure the health of the operator.
All of these are essential for the safety and operation of 1,3-di- (2-toluene) guanidine, and must not be ignored in order to ensure that everything goes smoothly and there is no safety hazard.

Application Area

In the field of chemical synthesis, it can be a key auxiliary agent, promoting the smooth reaction and improving the quality and yield of the product. In the field of material research and development, it may participate in the construction of novel material structures and endow materials with specific properties, such as enhancing their stability and flexibility. In the field of pharmaceutical exploration, after suitable modification and research, or with potential pharmacological activity, it is expected to become the lead structure of new drugs. Its wide application, such as the stars are empty, if carefully studied over time, it will be able to shine brightly in various application fields, contribute to the development of many industries, and bring about innovation.

Research & Development

In recent years, I have been studying chemical substances, especially 1,3 - Di - (2 - Tolyl) Guanidine. This material quality is very different, and it has extraordinary effects in many reactions. When I first studied it, I felt that its structure was exquisite, and it seemed to hide endless mysteries.
I have traversed the classics, looking for the accounts of the predecessors, but I have written very little. Then I set up various experiments to explore its nature. Looking at its integration with other things, whether gentle or strong, the phenomena are one after another. After months of hard work, I know a thing or two about it.
At this time, although I have gained something, the road ahead is still far away. If I want to expand its use, it can be used in the fields of medicine and materials. We must study it diligently and strive to make progress in order to promote the development of this substance and contribute to the chemical industry.

Toxicity Research

Today there is a substance named 1,3-di- (2-toluene) guanidine. As a chemical researcher, I have studied its toxicity for a long time. The toxicity of this substance is related to everyone's health and cannot be ignored.
I observe its structure, think about its reaction, and deduce its changes in the body. After various experiments, observe its impact on living things. Or damage the function of cells, or disrupt the normal order of metabolism.
Although the current knowledge is still limited, the suspicion of toxicity cannot be ignored. In the future, we should use rigorous methods to search for extensive data and investigate its nature in depth. I hope to be able to understand the depth of its poison, provide evidence for protection and use, and protect everyone from its harm, so that this thing can be used properly to avoid its scourge.

Future Prospects

Today there is a thing named 1,3-di- (2-toluene) guanidine. As a chemical researcher, I look at this substance and think about its future development. This substance has unique properties and may be useful in many fields. Although the current knowledge is still shallow, I firmly believe that with time, I will be able to explore its mysteries in depth. In the future, it may be used for the research and development of new materials to make the properties of materials even more outstanding; or it may emerge in the field of medicine, adding a weapon to cure diseases and save people. We should study it tirelessly to uncover its veil, develop its potential, and make it shine in the future, for the well-being of the world, open up new territories, and live up to the prospect of the future.

Frequently Asked Questions

What is the chemical structure of 1,3-Di- (2-Tolyl) Guanidine?

1% 2C3 - Di - (2 - Tolyl) Guanidine, its chemical structure is also. This compound belongs to guanidine derivatives. Looking at its name, 1,3 - bis - (2 - toluene) guanidine, the outline of its structure can be inferred.
"1,3 - di -", said that there are substituents at the 1st and 3rd positions of the guanidine group. " (2 - toluene) " means that the substituent is o-toluene. In the case of toluene, the benzene ring is connected to a methyl group, and in the case of 2 - position, that is, the methyl group is connected to a specific position of the benzene ring, and this specific position is separated from the place where the guanidine group is connected.
The structure of the guanidine group itself, centered on a nitrogen atom, connects two amino groups (-NH2O) with another imino group (= NH). In this compound, 1,3-di- (2-toluene) guanidine, that is, the nitrogen atoms at the 1st and 3rd positions of the guanidine group, are each connected to an o-toluene group.
In its structure, the benzene ring has six carbon atoms, which are in the shape of a hexagonal ring, and the methyl group is attached to a specific position in the benzene ring. The guanidine group and the benzene ring are connected by a covalent bond, and the atoms are bound according to their valence bond rules, resulting in the chemical structure of 1% 2C3 - Di - (2 - Tolyl) Guanidine. In this way, its structural characteristics are described in words, making it clear.

What are the main application fields of 1,3-Di- (2-Tolyl) Guanidine?

1% 2C3-di- (2-methylphenyl) guanidine, this substance has important applications in many fields. In the field of materials science, it can be used as a key auxiliary agent in the preparation of polymers. Due to its unique chemical structure, it can interact with polymer molecules to optimize material properties. For example, when synthesizing high-performance engineering plastics, appropriate addition can enhance the toughness and thermal stability of plastics, so that the finished products can still maintain good mechanical properties in high temperature environments, and are widely used in the manufacture of automotive and electronic equipment components.
In the field of organic synthesis chemistry, it is an important organic synthesis intermediate. With its guanidine-based active groups, it can participate in a variety of chemical reactions, such as reacting with halogenated hydrocarbons to form new organic guanidine compounds. These products have great potential in the field of medicinal chemistry and can be used to develop drug molecules with specific biological activities, providing new avenues for innovative drug research and development.
In the field of catalysis, it also shows unique value. It can be used as an organic base catalyst to catalyze specific organic reactions. In some condensation reactions and cyclization reactions, it can effectively activate reactant molecules, reduce reaction activation energy, and improve reaction efficiency and selectivity. Compared with traditional metal catalysts, it has the advantages of environmental friendliness, easy preparation and separation, and conforms to the development trend of green chemistry. It has broad application prospects in the synthesis of fine chemical products.

What are the physical properties of 1,3-Di- (2-Tolyl) Guanidine?

1% 2C3 - Di - (2 - Tolyl) Guanidine is 1,3 - bis (2 - methylphenyl) guanidine. The physical properties of this substance allow me to explain in detail.
Looking at its morphology, under normal conditions, 1,3 - bis (2 - methylphenyl) guanidine is mostly white to light yellow crystalline powder. This morphological characteristic is quite critical in many chemical reactions and industrial applications. Because of its powder shape, it is easier to mix evenly with other substances to promote the reaction.
Talking about the melting point, the melting point of this substance is about 170 - 174 ° C. Melting point is one of the important physical properties of a substance, which plays a decisive role in its state transition under different temperature conditions. In this temperature range, 1,3-bis (2-toluene) guanidine will melt from a solid state to a liquid state. This property is widely used in the fields of material processing and purification.
Furthermore, solubility is also an important physical property. 1,3-bis (2-toluene) guanidine is slightly soluble in water, but soluble in common organic solvents such as ethanol and acetone. This solubility characteristic determines its dispersion and reactivity ability in different solvent systems. In organic synthesis reactions, its solubility in organic solvents can be used to select suitable solvents to create a good reaction environment.
In addition, the density, odor and other physical properties of 1,3-bis (2-methylphenyl) guanidine also have their own unique characteristics. Its density is moderate and the odor is relatively weak. Although these properties appear to be subtle, they have a significant impact on the operating environment and product quality during actual use and storage.
To sum up, the physical properties of 1,3-bis (2-methylphenyl) guanidine are interrelated in various aspects, from morphology, melting point to solubility, etc., which together determine its application and value in many fields such as chemistry and materials.

What are the synthesis methods of 1,3-Di- (2-Tolyl) Guanidine?

1% 2C3 - Di - (2 - Tolyl) Guanidine is 1,3 - bis (2 - toluene) guanidine. The common synthesis methods are as follows:
First, 2 - methylaniline and dicyanamide are used as starting materials. 2 - methylaniline and dicyanamide are placed in a reactor in a certain proportion, and an appropriate amount of catalyst is added, such as some metal salt catalysts. Warm up to a specific temperature, usually between 150 ° C and 200 ° C, and the reaction lasts for several hours at this temperature. In this process, the amino group of 2-methylaniline undergoes nucleophilic addition reaction with dicyandiamide to gradually form 1,3-bis (2-toluene) guanidine. After the reaction, the crude product can be obtained by cooling, filtering, washing, etc., and then further purified by recrystallization.
Second, 2-methylphenyl isocyanate and 2-methylaniline are used as raw materials. In an organic solvent, such as toluene or xylene, 2-methylphenyl isocyanate is slowly added dropwise to the solution containing 2-methylaniline, and stirred at the same time. The reaction temperature is preferably controlled at 40 ° C to 60 ° C. During the reaction, 2-methylphenyl isocyanate and 2-methylaniline undergo an addition reaction to form the target product 1,3-bis (2-methylphenyl) guanidine. After the reaction is completed, the solvent is removed, and the separation and purification are carried out by column chromatography or recrystallization.
Third, 2-methylbenzonitrile, 2-methylaniline and ammonia are used as raw materials. In the high-pressure reactor, an appropriate amount of catalyst and solvent are added, ammonia is introduced, and 2-methylbenzonitrile and 2-methylaniline are added at the same time. Under these conditions, 2-methylbenzonitrile reacts with ammonia to form an intermediate amidine, followed by further reaction with 2-methylaniline to obtain 1,3-bis (2-methylphenyl) guanidine. After the reaction, the pressure is lowered, and the product is separated and refined to obtain high-purity 1,3-bis (2-methylphenyl) guanidine.

What are the precautions for using 1,3-Di- (2-Tolyl) Guanidine?

1% 2C3 - Di - (2 - Tolyl) Guanidine is also a chemical substance. When using it, many precautions must not be ignored.
Bear the brunt of it, and safety protection is essential. This substance may be toxic and irritating, and it must be fully armed when coming into contact. Wear chemical protective gloves on both hands to prevent skin contamination, allergies or other damage. A protective mask should also be worn on the face, and goggles are indispensable to protect against the harm to the eyes. Between breaths, a gas mask should be used to avoid inhalation and damage to the respiratory tract.
Furthermore, caution should be used in storage. Store in a cool, dry and well-ventilated place, away from fire and heat sources. Do not mix with oxidants, acids, etc., because of its active chemical properties, easy to react and cause danger.
During use, the operating specifications should not be underestimated. It needs to be carried out in a fume hood to ensure air circulation and reduce the concentration of harmful gases. When taking it, measure it accurately, according to experimental or production needs, not more or less. Use complete utensils and wash them in time to prevent residual substances from affecting the next use or causing other chemical reactions.
In addition, it is also necessary to know emergency treatment methods. If you accidentally come into contact with the skin, rinse with a large amount of flowing water immediately, and then seek medical treatment. If you come into contact with the eyes, immediately lift the eyelids, rinse with flowing water or normal saline, and seek medical attention as soon as possible. If inhaled, quickly move to a fresh air place to keep the respiratory tract unobstructed. If breathing difficulties require oxygen and the situation is critical, seek medical attention immediately.
All of these are important precautions when using 1% 2C3 - Di - (2 - Tolyl) Guanidine. Keep in mind that you cannot slack off in order to ensure safety and promote smooth experimentation or production.