1-Morpholinocarbonimidoylguanidine chemical structure of hydrochloride
1 - Morpholinocarbonimidoylguanidine and Hydrochloride, that is, 1 - morpholine formamidine guanidine, and hydrochloric acid, the product of the combination of the two is a salt compound. 1 - morpholine formamidine guanidine, disassembled from its name, "morpholine" is a nitrogen-containing six-membered heterocyclic structure, the nitrogen atom on this ring can be connected to the "formamidine" part, and "formamidine" has the structural characteristics of\ (-C (= NH) NH-\), "guanidine" has a similar structure of\ (-C (= NH) NH_2\), and there is the possibility of being connected to formamidine. When reacted with hydrochloric acid, the hydrogen ion in hydrochloric acid will combine with the nitrogen-containing part of 1-morpholine formamidine guanidine to form the corresponding salt. In its structure, the nitrogen atom of the original 1-morpholine formamidine guanidine is attractive to hydrogen ions because of its lone pair electrons. After the addition of hydrogen ions, the overall charge distribution and chemical properties are changed. The resulting salt, due to the introduction of hydrochloric acid part, has different solubility and stability than the parent compound of 1-morpholine formamidine guanidine, and its crystal structure and physical and chemical properties are unique due to this combination. The specific structure of this compound needs to be accurately determined by chemical analysis methods such as X-ray single crystal diffraction, but according to its composition and reaction principle, its approximate chemical structure characteristics can be preliminarily inferred.
What are the main uses of 1-Morpholinocarbonimidoylguanidine hydrochloride?
1 - Morpholinocarbonimidoylguanidine and Hydrochloride are chemical agents with a wide range of uses. In the field of medicine, this compound is often used as a key intermediate for drug research and development. When doctors want to make drugs with specific effects, they need to use their unique chemical structure to achieve precise effects on targets in organisms, and then exert therapeutic effects. For example, targeted drug preparation for specific diseases may be used.
In the chemical industry, it can be used as a catalyst or reaction aid. In many reactions in chemical production, it can change the reaction rate, make the reaction more efficient to the expected product, improve production efficiency and product purity, and help the smooth progress of chemical production.
In scientific research, this compound is also an important research object. By studying its reaction characteristics and chemical properties with other substances, researchers can deepen their understanding of the basic theories of related chemical fields, contribute to the development of chemical disciplines, expand the boundaries of chemical knowledge, and explore new reaction paths and chemical phenomena.
What are the physical properties of 1-Morpholinocarbonimidoylguanidine Hydrochloride?
The compound formed by 1-Morpholinocarbonimidoylguanidine and Hydrochloride is a unique chemical substance with many physical properties. Its properties may be crystalline solids, often white to off-white in appearance, delicate in texture, or with a specific luster under light.
When it comes to solubility, this compound may perform well in specific organic solvents. In water, its solubility may be characterized by the interaction of various groups in the molecular structure with water molecules. Some groups or form hydrogen bonds with water to help them dissolve, but the overall solubility is also restricted by factors such as the overall polarity of the molecule.
Melting point and boiling point are important physical parameters. Its melting point may be in a specific temperature range. At this temperature, the substance changes from the solid state to the liquid state. The transition temperature is closely related to the intermolecular forces, such as van der Waals forces, hydrogen bonds, etc. The same is true for the boiling point, which reflects the energy required for the transformation of the compound between the gaseous state and the liquid state.
In terms of density, it may have a specific value. Compared with the density of other similar compounds, the difference can be explained from the perspective of molecular size and packing method. In addition, its optical properties such as refractive index are also unique, which are related to the refraction and scattering of light by molecules, reflecting the influence of the microstructure of the compound on the propagation of light. All these physical properties are of great significance for the study of the application of this compound in chemistry, medicine and other fields.
What is the preparation method of 1-Morpholinocarbonimidoylguanidine Hydrochloride?
To prepare 1 - Morpholinocarbonimidoylguanidine hydrochloride, the method is as follows:
First take an appropriate amount of guanidine compound and dissolve it in a suitable solvent. This solvent needs to be able to dissolve guanidines well and has stable properties, and does not side-react with reactants and products. Common such as anhydrous ethanol, dichloromethane, etc.
Take another carbimide reagent containing morpholine group and slowly add it to the above guanidine solution. The addition process should be carried out at low temperature and stirred to ensure a uniform reaction. Low temperature can be achieved by ice bath or low temperature cooling device, and stirring will make the reactants fully contact and speed up the reaction rate.
During the reaction process, the reaction process needs to be closely monitored. Thin-layer chromatography (TLC) and other means can be used to observe the consumption of reactants and the formation of products. When the reaction reaches the expected level, stop the reaction and treat the reaction solution.
If the reaction solvent is low boiling point, the solvent can be removed by vacuum distillation to leave the crude product.
The crude product can be purified by a suitable method, and column chromatography is commonly used. Select suitable stationary and mobile phases to effectively separate the product from impurities, collect the eluent containing the pure product, and then concentrate and dry to obtain a relatively pure 1-Morpholinocarbonimidoylguanidine.
Finally, the resulting 1-Morpholinocarbonimidoylguanidine is reacted with an appropriate amount of hydrochloric acid. The reaction conditions are mild, and the reaction ratio and reaction time are controlled to ensure the formation of the target product 1-Morpholinocarbonimidoylguanidine hydrochloride. After the reaction is completed, the final product can be obtained through crystallization, filtration, drying and other steps. The whole process requires fine operation and attention to the control of each reaction condition to obtain high-quality products.
1-Morpholinocarbonimidoylguanidine Hydrochloride in storage and transportation
1 - Morpholinocarbonimidoylguanidine and Hydrochloride, when storing and transporting, many matters need to be paid attention to.
These two are unique in nature. When storing, the first environment is dry. Moisture can easily cause it to deteriorate and damage its quality. In the warehouse, the humidity should be strictly limited, and should not exceed a specific number to prevent moisture decomposition and other things. And the temperature must also be carefully controlled. Overheating or overcooling can cause chemical changes. A moderate temperature is appropriate to ensure the stability of its chemical properties.
Furthermore, it has a certain chemical activity and cannot be co-stored with strong oxidizing agents, reducing agents, etc. If it is in the same room, it may cause danger due to chemical reactions, such as fire or explosion. It must be classified and placed according to its chemical characteristics, and strictly distinguished.
When transporting, the packaging must be sturdy. Wrap it with suitable materials to prevent it from leaking. Road conditions are bumpy or cause damage to the packaging, so it is necessary to choose the best material reinforcement. And the transportation vehicle should also be clean, without other residues, so as not to react with it.
In addition, during the handling process, the operator must abide by the procedures. Wear suitable protective equipment, such as gloves, goggles, etc., to prevent contact and injury. Load lightly and unload lightly, do not allow collision and fall, and keep it safe.
All of these are for the storage and transportation of 1-Morpholinocarbonimidoylguanidine and Hydrochloride. Pay attention to them. There should be no slight negligence, so as to ensure the safety and quality.