2-(3-Chlorophenyl)Guanidine

Lingxian Chemical

Specifications

HS Code	456876
Name	2-(3-Chlorophenyl)Guanidine
Chemical Formula	C7H8ClN3
Molar Mass	169.61 g/mol
Solubility In Water	Limited solubility likely, as it is an organic compound with a hydrophobic phenyl group
Pka	Relevant for its basicity, specific value depends on experimental conditions

Packing & Storage

Packing	Packed in 1 - kg bags: 2-(3 - Chlorophenyl)Guanidine for chemical use.
Storage	2-(3 - Chlorophenyl)Guanidine should be stored in a cool, dry place, away from sources of heat and ignition. Keep it in a tightly - sealed container to prevent moisture absorption and exposure to air, which could potentially degrade the chemical. Store it separately from incompatible substances, such as strong oxidizers or acids, to avoid reaction risks. Ensure proper labeling for easy identification and follow safety regulations.
Shipping	2-(3 - Chlorophenyl)Guanidine is shipped in accordance with strict chemical transportation regulations. Packaged securely in suitable containers to prevent leakage, it is transported by professionals ensuring safe handling during transit.

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General Information

Historical Development

The most common substance is 2- (3-chlorophenyl) guanidine. Although it has not been known for a long time in chemical substances, it still has its unique development trajectory. At the beginning, various sages delved into the field of chemistry and searched for various reaction paths and material combinations. At the beginning, the properties and production methods of this substance were still ignorant, with only a little speculation and inference.
Later, with the advancement of skills and the increase of knowledge, many researchers gradually understood the method of its synthesis. Or change the conditions of the reaction, or easy to participate in the raw materials, and make unremitting efforts to eventually obtain a more efficient and stable preparation method. This process is also like clearing the clouds to see the sun, step by step, making 2- (3-chlorophenyl) guanidine gradually appear in the dark, adding a unique material to the field of chemistry. Its development path is in line with the general trend of chemical progress, from shallow to deep, from sparse to dense, and is improving day by day.

Product Overview

Today there is a substance named 2- (3 -chlorophenyl) guanidine. Its shape or white crystalline powder with a specific chemical structure. In the field of organic synthesis, it is often used as a key intermediate.
This compound contains chlorophenyl and has unique chemical activity. Its guanidine group also gives special reactive properties and can participate in many condensation and substitution reactions.
In the pharmaceutical industry, the cleverly designed reaction path may be converted into a substance with specific pharmacological activity, which may have potential therapeutic effects on certain diseases. During scientific research, chemists study its reaction characteristics, physicochemical properties in detail, hoping to expand its application scope, and add bricks and mortar to the chemical, pharmaceutical and other industries, so that it can shine in related fields.

Physical & Chemical Properties

The physicochemical properties of 2 - (3 - chlorophenyl) guanidine are of paramount importance. Its outer surface is often white crystalline, which is the most important characteristic of visual discernability. In terms of solubility, it is different in different solubility, such as water and water. In terms of solubility, this characteristic determines its dispersion and reaction activity in multi-chemical reactions and application scenarios. In addition, its characterization cannot be ignored. Under normal conditions, it can maintain the stability of the phase. However, when encountering specific components, such as high-quality, low-acid, etc., it may be biochemically transformed and induced to change. General physicalization is the cornerstone of in-depth study of this material and expansion of its application in the field.

Technical Specifications & Labeling

The technical specifications and identification (product parameters) of 2 - (3 - chlorophenyl) guanidine are crucial to the technical specifications and identification (product parameters) of this product. When making this product, the first raw materials are selected, and the raw materials of high quality and purity should be selected, and their parameters must be checked in detail to ensure that they meet specific standards.
The production process must also be strictly controlled, and each step must be operated according to precise procedures. From the initial chemical reaction to the subsequent purification and refining, there should be no slight mistakes. Temperature, time, proportion of reactants and other factors need to be strictly controlled.
Furthermore, the product identification should not be underestimated. When the product name, ingredients, purity, scope of application, precautions and other key information are clearly marked, so that the user can see at a glance, in order to ensure the safety and effectiveness of the product use, and to demonstrate our respect and adherence to technical specifications and labels (product parameters).

Preparation Method

The raw materials and production process, reaction steps and catalytic mechanism of 2 - (3 - chlorophenyl) guanidine are the key to the preparation of 2 - (3 - chlorophenyl) guanidine. Take 3 - chloroaniline as the starting material and react with sodium cyanate in a suitable solvent at a temperature control. During the process, the properties of the solvent and the degree of temperature must be precisely controlled. After the reaction is completed, the intermediate product is obtained by separation and purification.
Then, the intermediate product is reacted with ammonium chloride under specific conditions. In this process, the adjustment of reaction time and pH is very important. Use a suitable catalyst to accelerate the reaction process, optimize the catalytic mechanism, and improve the yield and purity. After several refining processes, 2 - (3 -chlorophenyl) guanidine is finally obtained. Each step needs to be carefully operated and followed by specifications in order to obtain high-quality products.

Chemical Reactions & Modifications

Nowadays, there is a species named 2- (3-chlorophenyl) guanidine. In the field of chemistry, its reaction and modification are quite critical. If you want to study the methods of chemistry in the past, you must carefully observe the changes in the reaction.
The chemical reaction of this 2- (3-chlorophenyl) guanidine may involve the breaking and formation of bonds. If it comes into contact with other substances, or due to the transfer of electrons, new substances are formed. As for the way of modification, it can be done by changing chemical reagents, temperature and pressure.
If its structure is changed, its physical and chemical properties may be changed. If the arrangement of its molecules is adjusted, its solubility and stability may be different from before. In order to achieve the wonders of chemistry, the reaction and modification of 2- (3-chlorophenyl) guanidine should be studied in depth to understand the secrets of chemical changes and pave the way for future applications.

Synonyms & Product Names

2 - (3 - chlorophenyl) guanidine is a synonymous name and a commodity, which is really important in chemical research. In my opinion, in the field of chemistry, it is common to see more than one thing. 2 - (3 - chlorophenyl) guanidine, or another name for different situations and uses. Its synonymous name, or based on its chemical structure and properties, aims to accurately express its essence. The name of the commodity, or for the convenience of market circulation and distinction, is determined by merchants. Although both refer to this thing, they have different focuses. The name of the synonym emphasizes academic accuracy; the name of the commodity emphasizes market identification. Chemical researchers need to be discerning and use it as needed in research and application, so that the research can be smooth and the application is appropriate.

Safety & Operational Standards

Regarding the safety and operation specifications of 2- (3-chlorophenyl) guanidine products
Fu2- (3-chlorophenyl) guanidine, the product of the chemical is also. In the context of experiment and production, safety and operation standards are of paramount importance.
As far as the safety end is concerned, this product may pose a certain hazard. Avoid the touch of the skin and the suction of the mouth and nose. If you accidentally touch the skin, rinse it with a lot of water quickly. If you feel unwell, seek medical attention. If it enters the eye, you should also wash it slowly with water and seek medical assistance. If the gas may be irritating, the place where you work should be kept well ventilated so that the turbid gas can dissipate quickly.
As for the operation specifications, those who handle this thing must have professional knowledge and skilled skills. When weighing, be sure to use precise tools, and take them according to the specified quantity. There should be no slight mistakes. Mixing steps should be done slowly, and stirred properly to prevent sudden changes. During the reaction process, keep in mind the conditions such as temperature and pressure, and do not change them according to the established regulations. When storing, it is advisable to keep in a cool and dry place, avoid fire and heat, and store them in categories with other things to prevent them from disturbing and changing.
In short, the safety and operating standards of 2- (3-chlorophenyl) guanidine are related to the success or failure of the experiment and the stability of the production. The operator must observe and follow them to ensure safety.

Application Area

2 - (3 -chlorophenyl) guanidine is a compound that has great application in the field of medicine. It can be used to create new antibacterial agents. With its unique chemical structure, it interferes with the metabolism and reproduction of pathogens, adding a weapon to fight infections and diseases. In agriculture, it can be developed into plant disease prevention and control agents to protect the healthy growth of crops. In materials science, it can participate in the synthesis of special materials and endow materials with specific properties, such as improving their stability and enhancing adsorption force. Its application field is wide and its potential is huge. With time, in-depth investigation, it will be able to shine in various fields and benefit mankind.

Research & Development

In recent years, more than 2- (3-chlorophenyl) guanidine has been studied with much effort. The characteristics of this compound are unique and the potential is obvious. At the beginning, to explore the method of its synthesis, after various attempts, or due to the limitations of raw materials, or due to the difficult control of reaction conditions, it was repeatedly hindered. However, the remaining did not give up, repeated deductions, and finally a feasible path.
Synthesis has been completed, and its properties have been restudied. After careful analysis, it is known that its chemical activity is quite good, and it is unique in specific reactions. And looking at its structure, it may be useful in the fields of medicine, chemical industry, etc. Therefore, it seeks to expand its application and discuss with colleagues, with the hope of exploring more potential, promoting its development, and making this compound stand out in various industries, adding new color to both academia and industry.

Toxicity Research

The study of the toxicity of 2- (3 - Chlorophenyl) Guanidine is of great importance. Today, we want to investigate this substance in detail to understand its toxicity. Looking at the tests of all kinds of poisons in the past, we are cautious. In the study of 2- (3 - Chlorophenyl) Guanidine, the same should be true.
First examine its chemical properties and structural analysis to observe its possible changes. Next, look at its behavior in different environments, in water, soil, and gas, or decomposition, or chemical combination, and investigate the new substances it produces, and what changes in toxicity.
It is also experienced in various organisms, such as insects, fish, and beasts. It is different in body shape, habits, and physiological functions when they are invaded by this substance. Nymphs, or growth retardation, or erratic behavior; fish, or shortness of breath, or change in color; beasts, or mental weakness, or organ damage.
All these, recorded in detail, summarized, and hoped to know the toxicity of 2- (3 - Chlorophenyl) Guanidine, which is helpful for later generations to avoid harm and benefit, protect the well-being of all beings, and protect the balance of ecology.

Future Prospects

Fu2- (3-chlorophenyl) guanidine is promising for future development in the field of chemical research in China. Its structure is unique and its properties are also interesting.
The current research situation of Fufu, many scholars focus on its reaction mechanism. If we can understand the mystery, we will be able to optimize the synthesis method and improve the yield and purity. With time, a more efficient and environmentally friendly preparation path may be found.
Furthermore, 2- (3-chlorophenyl) guanidine has potential uses in the direction of pharmaceutical research and development. The exploration of its pharmacological activity is in the ascendant. After in-depth research, it may lead to the development of new drugs, which will contribute extraordinary power to human health and well-being.
I firmly believe that with the unremitting research of many researchers, the future of 2- (3-chlorophenyl) guanidine will be like a bright star, shining brightly, and creating a new brilliant chapter in chemistry and related fields.

Frequently Asked Questions

What are the main uses of 2- (3-chlorophenyl) guanidine?

2-%283-%E6%B0%AF%E8%8B%AF%E5%9F%BA%29%E8%83%8D, that is, 2 - (3 - aminopropyl) silane, its main uses are as follows:
This substance plays a key role in many fields. In the field of material surface modification, its function is very great. Because its molecules contain active silane groups and amino groups, silane groups can chemically react with hydroxyl groups on the surface of the material to form strong chemical bonds, so that amino groups can be successfully grafted to the surface of the material. As a result, the surface properties of the material can be significantly changed, the hydrophilicity is greatly improved, and the adsorption performance of specific substances is enhanced. For example, in glass fiber reinforced composites, the use of 2- (3-aminopropyl) silane to treat the surface of glass fibers can greatly enhance the interfacial bonding force between glass fibers and resin matrices, and greatly improve the mechanical properties of composites. Key indicators such as tensile strength and flexural strength can be significantly improved.
In the preparation of organic-inorganic hybrid materials, 2- (3-aminopropyl) silane is also indispensable. Silane hydrolysis polycondensation can form an inorganic silica network structure, and amino groups can react or interact with organic monomers, so that the organic phase and inorganic phase are ingeniously combined to prepare hybrid materials with unique properties. Like the preparation of hybrid coatings with good optical and mechanical properties, this substance is often used.
In the field of biomedicine, 2- (3-aminopropyl) silane also shows unique value. The surface of the modified biomaterial can promote cell adhesion, proliferation and biocompatibility due to the presence of amino groups. For example, modifying the substance on the surface of tissue engineering scaffold materials can provide a more suitable microenvironment for cell growth and facilitate tissue repair and regeneration.
In addition, in the field of catalyst supports, 2- (3-aminopropyl) silane can modify the surface of the support, introduce amino functional groups, facilitate the loading of active components, enhance the interaction between active components and supports, and improve the stability and activity of the catalyst.

What are the physicochemical properties of 2- (3-chlorophenyl) guanidine

The rationality of 2 - (3-aminophenyl) hydrazine is as follows:
The outer layer of this product may be solid. In many cases, its color or white to black powder may be different. Due to factors such as the content and storage environment, the color may be slightly different.
In terms of melting, it is roughly equal to a certain degree of solubility. This property can help to initially determine its solubility by fixed melting in a chamber. If the melting temperature of the product is close to the melting temperature of the text, it can be inferred that its degree of solubility is high; if the melting temperature is large or the melting temperature is offset, or it is implied that the product contains a certain degree of solubility.
In terms of solubility, in some soluble materials, such as ethanol, acetone, etc., or have a certain solubility. This property is very important in the synthesis of alcohol. In the synthesis process, it is necessary to dissolve it exactly according to its solubility, so as to facilitate the reaction. For example, in a specific reaction, the use of ethanol as a solution can fully dissolve 2- (3-aminophenyl) hydrazine, and other reactions are mixed to improve the reaction efficiency. However, in water, its solubility or phase is low. Qualitatively speaking, under normal conditions, if properly stored, the phase can be maintained. However, it is necessary to avoid oxidation, acid, and other substances, and do not react or lead to oxidation. For example, oxidation may cause oxidation reactions, causing molecules to be modified and affecting their original uses.
In addition, it has a certain chemical activity, and the hydrazine-aminophenyl group in the molecule can be polyaminated and reactive. The amino group in the aminophenyl group can be acylated, alkylated and other reactive groups. In the synthetic path, this reactive group can be used to introduce different functionalities and expand the polymorphism of compounds to meet the needs of different domains, such as chemical synthesis, material research, etc.

What is the synthesis method of 2- (3-chlorophenyl) guanidine?

To prepare 2 - (3 - cyanobenzyl) furan, the following method can be used.
First, 3 - chloromethylbenzoic acid is used as the starting material, and it is reacted with thiourea to obtain 3 - (aminothioformylmethoxy) benzoic acid. This step of the reaction needs to be carried out under appropriate solvent and temperature conditions. Solvents such as ethanol, etc., heating prompts the reaction to occur, and the transformation is achieved through nucleophilic substitution mechanism.
Next, 3 - (aminothioformylmethoxy) benzoic acid is cyclized and dehydrated to obtain 2 - (3 - carboxylbenzyl) furan. This process can be completed under the action of dehydrating agents, such as acetic anhydride and other dehydrating agents, at a suitable temperature and reaction time, through intramolecular dehydration to form a ring reaction to construct a furan ring structure. After
, 2- (3-carboxylbenzyl) furan reacts with thionyl chloride, the carboxyl group is converted into an acid chloride, and then nucleophilic substitution reaction occurs with sodium cyanide to obtain 2- (3-cyanobenzyl) furan. This two-step reaction requires attention to the control of the reaction conditions. When reacting with thionyl chloride, attention should be paid to the anhydrous environment. In the nucleophilic substitution step, attention should be paid to the amount of sodium cyanide and the pH of the reaction
Or, with 3-bromo-methyl-benzaldehyde as raw material, first react with diethyl malonate under alkaline conditions, and the basic reagents such as sodium ethyl alcohol, etc., undergo Knoevenagel condensation reaction to generate the corresponding unsaturated ester. Then through hydrolysis, decarboxylation and other steps, 2 - (3-aldehyde-benzyl) furan can be obtained. Finally, under the action of a suitable cyanide reagent, such as trimethylsilyl cyanide (TMSCN), the aldehyde group is converted into a cyanide group, thereby preparing 2 - (3-cyanobenzyl) furan. Each step of the reaction requires precise control of the reaction conditions to ensure that the reaction proceeds in the desired direction in order to obtain a product with higher yield and purity.

What are the precautions for 2- (3-chlorophenyl) guanidine during use?

2 - (3 -Alkanophenyl) hydrazine should pay attention to the following matters during use:
First, it is related to its chemical properties. This substance has specific chemical activity and is prone to react with many chemical substances. When storing and using, be sure to avoid co-location with strong oxidants, strong acids, strong bases, etc. Strong oxidants may cause severe oxidation reactions, and even trigger combustion or explosion; strong acids and strong bases may react with it, or change its chemical structure, causing it to lose its original properties or generate dangerous products.
Second, safety protection. Users must wear appropriate protective equipment, such as protective gloves, protective glasses, gas masks, etc. It may cause irritation and damage to the skin, eyes, respiratory tract, etc. If you accidentally come into contact with the skin, you should immediately rinse with a lot of water and seek medical attention as appropriate; if it splashes into the eyes, you need to rinse with a lot of flowing water immediately and continuously, and then seek medical attention as soon as possible.
Third, storage conditions are critical. It should be stored in a cool, dry and well-ventilated place, away from fire and heat sources. Avoid direct sunlight to prevent decomposition or other chemical reactions caused by rising temperature. Storage containers must also be tightly sealed to prevent them from evaporating into the air, and at the same time avoid absorbing moisture in the air and deteriorating.
Fourth, the use environment should be cautious. The operation should be carried out in a fume hood to ensure that volatile gases can be discharged in time and reduce the concentration of harmful substances in the air. If used in a place with limited space and poor ventilation, the accumulation of volatile gases will not only endanger the health of the operator, but may also cause safety accidents.
Fifth, the use specifications are strict. Before use, be sure to know its dosage and reaction conditions accurately, and must not change the established operating procedures at will. Due to improper dosage or deviation of reaction conditions, or the loss of control of the reaction, unpredictable consequences will be caused. After use, properly dispose of the remaining substances and waste, and do not discard them at will. They should be disposed of harmlessly in accordance with relevant regulations.

What is the market prospect of 2- (3-chlorophenyl) guanidine?

In today's world, the market prospect of 2 - (3 - cyanobenzyl) hydrazine is related to many parties.
Looking at its use, this substance has great potential in the field of pharmaceutical and chemical industry. In pharmaceutical research and development, it can be a key raw material for the creation of new drugs and help explore new ways to treat various diseases. Therefore, the demand for it by pharmaceutical companies may increase gradually with the development of new drugs. In chemical production, it can be used as an intermediate for special reactions to generate a variety of high-value-added products and expand chemical categories.
When it comes to market conditions, the global chemical and pharmaceutical industries are developing rapidly. Pharmaceutical innovation and chemical industry excellence are all opportunities for 2 - (3 - cyanobenzyl) hydrazine. However, there are also challenges. The synthesis process is complicated and the cost is high, which leads to the price being the highest, limiting its wide use. And the market competition is fierce, and the same industry is competing for profits. If you want to take the lead, you need excellent technology, low cost and good quality.
In addition, the impact of policies and regulations cannot be ignored. Environmental protection is becoming stricter, and the cost of production compliance is increasing. If compliance is not effective, or production is restricted. However, policies also encourage innovation. If you can use it to develop improved processes, reduce pollution and reduce costs, you will definitely have an advantage.
From a comprehensive perspective, although the market prospect of 2- (3-cyanobenzyl) hydrazine is bright and challenging, if we can break the synthesis problem, control costs, and follow the policy, we will be able to gain a broad market share, become the industry leader, and lead to industrial innovation.