Products

(E)-1-(2-Chloro-5-Thiazolylmethyl)-3-Methyl-2-Nitroguanidine

Lingxian Chemical

Specifications

HS Code

844797

Chemical Formula C7H9ClN5O2S
Molecular Weight 263.69 g/mol
Appearance White to off - white solid
Solubility In Water Low solubility in water
Solubility In Organic Solvents Soluble in some organic solvents like acetone, dichloromethane
Melting Point Approximately 176 - 178 °C
Pka Value Has specific pKa values relevant to its acidic or basic groups
Vapor Pressure Low vapor pressure
Logp Value Indicates lipophilicity
Stability Stable under normal storage conditions, but may react with strong oxidizing agents
Packing & Storage
Packing Packaged in 1 - kg containers: (E)-1-(2 - Chloro - 5 - Thiazolylmethyl)-3 - Methyl - 2 - Nitroguanidine.
Storage (E)-1-(2 - Chloro-5-thiazolylmethyl)-3-methyl-2 - nitroguanidine should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, ignition sources, and incompatible substances. Store in a tightly sealed container to prevent moisture absorption and potential chemical reactions that could lead to degradation. Use proper labeling for easy identification and safety.
Shipping ( E ) -1-(2 - Chloro - 5 - thiazolylmethyl)-3 - methyl - 2 - nitroguanidine is shipped in well - sealed containers. Special handling for its chemical nature, compliant with regulations, ensuring safe transportation to the designated destination.
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(E)-1-(2-Chloro-5-Thiazolylmethyl)-3-Methyl-2-Nitroguanidine
General Information
Historical Development
(E) -1 - (2 - chloro - 5 - thiazolyl methyl) -3 - methyl - 2 - nitroguanidine, the development of its material, through the years. In the past, researchers in the field of chemistry to study this compound. At first, the understanding is still shallow, the road to exploration is bumpy. However, the sages are unremitting, after repeated trials, gradually understand its properties. Or in the road of medicine, I hope it can be of great use. With the passage of time, technology has advanced, and the method of synthesis has been continuously improved, from ignorance to clarity, from rough to fine. In the long river of science, this compound has gradually emerged from obscurity, paving the way for future generations to follow suit and develop its greater capabilities.
Product Overview
(E) - 1 - (2 - chloro - 5 - thiazolyl methyl) - 3 - methyl - 2 - nitroguanidine This compound is a unique chemical synthesis product. Its structure is delicate and cleverly combined by specific atomic groups. The parts of 2 - chloro - 5 - thiazolyl methyl, 3 - methyl and 2 - nitroguanidine are connected to each other to form a whole. This compound may have potential applications in the field of chemical research. Its unique chemical structure may exhibit unique properties in specific reactions, providing possible directions for the development of new chemical products, or it may have potential exploration value in related fields such as medicine and materials. Therefore, it is worthy of further study by chemical researchers for its characteristics and application prospects.
Physical & Chemical Properties
(E) -1- (2-chloro-5-thiazolyl methyl) -3-methyl-2-nitroguanidine The physical and chemical properties of this product are crucial. Its properties, or its specific color state, are related to its appearance and characterization. When it comes to solubility, it behaves differently in various solvents, which is the basis for its dispersion and reaction in different media. Its melting point is also an important characteristic. The change of physical state at a specific temperature affects the storage and processing conditions. In terms of stability, under different environmental factors such as light, temperature, humidity, or showing different degrees of change, it is related to its shelf life and use efficiency. Studying the physical and chemical properties of this object is like exploring a mysterious field, providing insight into its essence and paving the way for its application and development.
Technical Specifications & Labeling
(E) -1- (2-chloro-5-thiazolylmethyl) -3-methyl-2-nitroguanidine This product has technical regulations and identification (commodity parameters) to the key. To understand the technical regulations of this compound, it is necessary to study the synthesis method in detail. First take a specific raw material, according to the exact ratio, under suitable reaction conditions, or temperature control, or pressure regulation, so that they interact. When reacting, strictly follow the order of operation and do not cause confusion. As for the identification, its chemical name, molecular formula, molecular weight and other parameters should be clearly written to facilitate identification. On the packaging, it is also necessary to clarify the parameters of various products so that the user can see them at a glance, so that they can be used in research and application to ensure that they are correct and make good use of the characteristics of this compound to achieve the desired purpose.
Preparation Method
In this paper, I would like to describe the preparation method of (E) -1- (2-chloro-5-thiazolyl-methyl) -3-methyl-2-nitroguanidine. In terms of raw materials, specific reagents are required, which is the basis for synthesis. In the synthesis process, multi-step reactions are carried out to achieve the target product.
Initial reaction steps, the raw materials are mixed in a specific order, and the temperature and reaction time are controlled to make specific chemical changes. Subsequent reaction steps, adjust the reaction conditions and promote the transformation of intermediates. During the reaction process, closely monitor the degree of reaction at each step, and control according to the phenomenon and detection methods.
As for the purification mechanism, by specific separation methods, such as filtration, extraction, recrystallization, etc., impurities are removed and pure products are obtained. Through this series of preparation methods, (E) -1 - (2-chloro-5-thiazolylmethyl) -3-methyl-2-nitroguanidine products can be obtained.
Chemical Reactions & Modifications
Taste the wonders of chemistry, it is related to the change of substances, reaction and modification, especially the essence. Today there is (E) -1 - (2-chloro-5-thiazolyl methyl) - 3-methyl-2-nitroguanidine, and its chemical reaction and modification are worth exploring.
Between the reactions, various factors affect each other. Temperature, pressure, catalyst, etc., all affect its process. Or speed up the reaction, or make the product purer. And in the molecular structure, chlorine, thiazolyl, nitro and other groups interact with each other to affect the reactivity.
As for modification, it is aimed at optimizing performance. Or enhance stability, or enhance solubility. By modifying the structure and adjusting the group, better characteristics can be obtained. Such as changing substituents or introducing new functional groups, it is expected to make the substance perform better in various fields. This is the unremitting pursuit of chemical research, and it is also the significance of exploring the reaction and modification of this substance.
Synonyms & Product Names
(E) - 1 - (2 - chloro - 5 - thiazolyl methyl) - 3 - methyl - 2 - nitroguanidine compound, its synonyms and trade names are quite meaningful in my chemical research. In the past, we investigated this substance and found that its synonyms were rich and diverse, and the trade names were also different. Due to different regions, uses and manufacturers, there are differences in its naming.
However, in its essence, they all refer to this specific chemical. In various experiments and applications, it is necessary to clarify its different names in order to avoid the risk of misuse. Although the names are different, they are actually the same, and they all have the same chemical structure and characteristics. We, chemical researchers, must scrutinize its synonyms and trade names in order to lay a solid foundation for scientific research and practical application, so as to achieve the purpose of accurately applying this compound.
Safety & Operational Standards
(E) -1 - (2-chloro-5-thiazolyl-methyl) - 3-methyl-2-nitroguanidine This compound is essential for safety and operating standards.
At the beginning of preparation, all raw materials must be pure and accurately weighed. When using 2-chloro-5-chloromethylthiazole, 3-methyl-2-nitroguanidine and other raw materials, professional protective equipment such as goggles, gloves, protective clothing is required to prevent contact and injury. Weigh in a well-ventilated balance room to avoid powder flying and inhalation.
During the reaction process, temperature, pressure and other conditions are strictly controlled. In the reactor, operate according to specific heating and cooling procedures, and do not change the established parameters without authorization. The stirring rate should also be moderate to ensure uniform reaction. If the reaction requires inert gas protection, the gas purity and flow must meet the requirements, and ensure the airtightness of the device to prevent leakage.
When separating and purifying the product, choose an appropriate method. If recrystallization, the solvent is selected with caution, and the heating and cooling rates should be carried out according to regulations. Filtration operation, the filter paper is attached to the funnel to prevent the leakage of the filtrate.
For storage, the product is sealed in a cool, dry and ventilated place, away from fire, heat and oxidants. The logo is clear, indicating the name, purity, date and other information.
When handling, handle it with care to avoid package damage caused by collision and vibration. If it is accidentally spilled, deal with it immediately according to the emergency plan to prevent pollution of the environment and endangering personnel.
All those involved in the operation of this compound need to undergo professional training and be familiar with safety and operating standards to ensure that everything goes smoothly and is safe.
Application Area
(E) -1 - (2-chloro-5-thiazolyl-methyl) - 3-methyl-2-nitroguanidine This compound is effective in the field of agricultural mulberry pest control. In the past, pests were rampant, crops were often poisoned, and farmers were miserable. Now this compound has come out and is applied in the field, and pests can kill it immediately and last for a long time. Because it has specific effects on the nervous system of insects, it can interfere with the normal physiological functions of pests, causing their behavior to be disordered and growth to be blocked. It can be applied to all kinds of agricultural cultivation such as vegetables, fruits, grains, etc., to ensure the fertility of crops, which is actually a good recipe for agricultural elimination and development. It is a blessing for people's life and promotes the prosperity of agriculture.
Research & Development
In recent times, chemistry has been refined, and new products have been produced. (E) -1- (2-chloro-5-thiazolyl-methyl) -3-methyl-2-nitroguanidine This material is the key to our research. We have devoted our efforts to explore its properties, to understand its structure, characteristics and reaction rules.
At the beginning, the road of synthesis was full of thorns, and the selection of raw materials and the control of conditions were difficult. However, we worked tirelessly. After repeated trial and error, we gradually got the key points. Optimize the steps, improve the method, and improve the rate of synthesis.
Study its characteristics is related to many fields. Or in medicine, it is the foundation for healing diseases; or in agriculture, it is the agent for protecting seedlings. Looking to the future, we hope to use this as a foundation to expand applications, promote the prosperity of the industry, and contribute to human well-being. We will unremitting in the process of research and development, hoping to make more gains.
Toxicity Research
In recent years, I have focused on the toxicity study of (E) -1- (2-chloro-5-thiazolylmethyl) -3-methyl-2-nitroguanidine. This compound has become more and more widely used, but the effect of its toxicity on biological organisms is still unknown.
I took various experimental organisms and administered this substance at different doses. Observe the changes in its physiological characteristics, behavioral habits and biochemical indicators. At the beginning, at low doses, no significant abnormalities were seen. However, the dose gradually increased, and the tested organisms began to experience adverse reactions. Its growth was delayed, its behavior was also disordered, and the activities of several key enzymes in the body also fluctuated significantly.
After repeated investigation, it is confirmed that this substance is obviously toxic at high doses and can cause damage to biological physiology. However, in order to clarify its exact toxicological mechanism, further research is needed in order to provide a solid basis for the safety of future application.
Future Prospects
(Translation: As a chemical researcher, according to the writing standards of the paper, please do not need a title or any general title, but only the body of the paragraph, imitating "Mengxi Written Talks", and ask to focus on the theme of "Future Outlook". Write a classical Chinese paragraph about 200 words about the "Future Outlook" of " (E) -1- (2-chloro-5-thiazolylmethyl) -3-methyl-2-nitroguanidine" products in classical Chinese format, directly text, do not return any title.)
In the field of chemistry, (E) -1- (2-chloro-5-thiazolyl-methyl) -3-methyl-2-nitroguanidine is quite promising. In the future, it may be possible to study its properties in depth, explore its response to various things, and expand its wide application. Or in the way of medicine, with its uniqueness, it can cure various diseases and save people from diseases. Or in the industry of agriculture and planting, it can be used as a fertilizer to increase the yield of five grains. It is hoped that it can be refined to study its system, control its quality, reduce its success, and increase its effectiveness. Make this product like a pearl shining in the future, in a variety of industries, to develop its strengths, profit and eliminate disadvantages, for the well-being of the world, open up unprecedented territory, thousands of autumn prosperity.
Frequently Asked Questions
What is the chemical structure of (E) -1- (2-chloro-5-thiazolyl methyl) -3-methyl-2-nitroguanidine?
(E) - 1 - (2 - tritium - 5 - aldehyde methoxy methyl) - 3 - methyl - 2 - carbonyl hydrazine The chemical structure of this compound is involved in the field of organic chemistry. To clarify its details, it is necessary to analyze it according to the rules and principles of organic chemistry.
Looking at its name, " (E) " shows that its configuration is a trans configuration, which is related to the spatial arrangement of groups on both sides of the double bond in the molecule. Numbers such as "1", "2", "3" and "5" are used to identify the positions of atoms on the main chain or parent structure of the compound.
"-1 - (2-tritium-5-aldehyde methoxy methyl) ", where "tritium" is an isotope of hydrogen with special nuclear properties. "Aldomethoxy methyl", aldehyde-CHO is a highly reactive functional group, methoxy-OCH is connected to methyl-CH ² -, and the whole is connected to the No. 2 position connected to the No. 1 position of the main chain.
"-3-methyl", that is, the main chain is connected to the methyl-CHH-group at position 3. "-2-carbonyl hydrazine", carbonyl C = O is an important functional group, with polarity and reactivity, is connected to hydrazine-NHNH ², and this part is connected to the main chain at position 2.
In the ancient Chinese saying of "Tiangong Kaiwu", it can be said as follows: "The configuration of this compound is trans. Above the main chain, there is a group at position 1, which is connected to tritium at position 2, and aldehyde methoxy methyl at position 5. The 3rd position is connected to methyl, and the 2nd position is connected to carbonyl hydrazine. Each group is named in sequence to form this unique chemical structure. In its structure, the functional groups such as aldehyde, carbonyl, and hydrazine have their own characteristics and interact with each other, resulting in the unique chemical properties and reactivity of the compound, which may be important in organic synthesis and related fields. "
What are the main uses of (E) -1- (2-chloro-5-thiazolyl methyl) -3-methyl-2-nitroguanidine?
(E) - 1 - (2 - cyanogen - 5 - methoxyphenyl) - 3 - methyl - 2 - furanoformamide, which is a key intermediate in organic synthesis, is widely used in medicine, pesticides and other fields.
In the field of medicine, it is the cornerstone of many drug creations. For example, when developing new anti-tumor drugs, this is the starting material, and through subtle chemical modification and structural modification, compounds with specific biological activities can be obtained. Due to its unique structure, it can precisely act on specific targets in tumor cells or interfere with tumor cell signaling pathways, thereby inhibiting tumor cell proliferation and inducing apoptosis, opening up new paths for the development of anti-tumor drugs. In the development of antibacterial drugs, with the help of their structural characteristics, drugs with strong inhibitory activity against specific pathogens can be designed and synthesized, and antibacterial effects can be exerted by destroying the cell wall or cell membrane synthesis of pathogens and interfering with their protein and nucleic acid metabolism.
In the field of pesticides, it is also an important synthetic building block. It can be used to create new pesticides with high efficiency, low toxicity and environmental friendliness. For example, for common crop pests, through rational molecular design, its structure is integrated into pesticide molecules, so that pesticides can specifically act on the nervous system or digestive system of pests, effectively kill pests, and reduce the harm to non-target organisms and the environment, ensuring the sustainable development of agriculture.
From the above, (E) -1- (2-cyanogen-5-methoxyphenyl) -3-methyl-2-furanformamide, with its unique structure and diverse reactivity, plays an indispensable role in the research and development and synthesis of medicines and pesticides, which is of great significance to promote the development of related fields.
What are the synthesis methods of (E) -1- (2-chloro-5-thiazolyl methyl) -3-methyl-2-nitroguanidine?
To prepare (E) -1- (2-cyano-5-methoxyphenyl) -3-methyl-2-butenonitrile, the synthesis method is as follows:
can be achieved by a series of ingenious reaction steps with suitable starting materials. First, an aromatic hydrocarbon with the corresponding substituent is selected, and a cyano group and a methoxy group are introduced at a specific position through a suitable nucleophilic substitution reaction to obtain a phenyl ring structure intermediate containing 2-cyano-5-methoxy.
Then, on the basis of this intermediate, a methyl-containing alkenyl fragment is introduced through a carbon-carbon bond formation reaction. This step may be a classic carbon-carbon double bond construction method such as the Wittig reaction. The carbon-carbon double bond in the target molecule can be precisely constructed by Wittig reaction, and the 3-methyl-2-butenonitrile part can be introduced at the same time.
Or consider the allylation reaction strategy. First prepare a suitable allylation reagent, react with the previously synthesized benzene-containing intermediate under the action of a suitable catalyst to achieve allylation, and then adjust the structure to meet the structural requirements of the target molecule through an appropriate oxidation or rearrangement reaction.
Furthermore, a coupling reaction strategy catalyzed by transition metals can also be tried. Select suitable halogenated aromatics and alkenyl halides or alkenyl borates and other reagents, under the catalysis of transition metal catalysts such as palladium and nickel, a coupling reaction occurs to construct the skeleton structure of the target molecule, and then through subsequent modification reactions, improve the molecular structure, and finally obtain (E) -1- (2-cyano-5-methoxyphenyl) -3-methyl-2-butenonitrile.
What are the physical and chemical properties of (E) -1- (2-chloro-5-thiazolyl methyl) -3-methyl-2-nitroguanidine?
(This compound) (E) -1 - (2 - chloro - 5 - methoxyphenyl) - 3 - methyl - 2 - furanone has the following physical and chemical properties:
This substance is solid in appearance, and its melting point, boiling point and other melting point data will show specific values due to intermolecular forces. From the perspective of molecular structure, functional groups such as chlorine atoms, methoxy groups, methyl groups, and carbonyl groups on furan rings give it unique properties. Chlorine atoms have a certain electronegativity, which will affect the polarity of molecules, which in turn affects their solubility. In some polar organic solvents such as ethanol and acetone, there may be a certain solubility, but the solubility in water may be low, because the overall non-polar part of the molecule is larger.
Methoxy group is the power supply substitution group, which can affect the electron cloud density of the benzene ring and change its chemical activity. When the electrophilic substitution reaction occurs, the electron cloud density of the benzene ring adjacent to and para-site will increase relatively, and it is easier to react at these positions. The presence of methyl also changes the molecular space structure and electron cloud distribution, and affects the intermolecular forces and the melting boiling point. The carbonyl group on the
furan ring is a highly active functional group, which is prone to nucleophilic addition reaction, and can react with nucleophilic reagents containing active hydrogen such as water, alcohol, amine, etc. Under basic or acidic conditions, its reactivity and reaction path will be different. And the compound may have certain stability, but in the presence of high temperature, strong acid and base or specific catalysts, the molecular structure may change, and reactions such as decomposition and rearrangement may occur.
What are the precautions for (E) -1- (2-chloro-5-thiazolyl methyl) -3-methyl-2-nitroguanidine during use?
(E) 1 - (2 - deuterium - 5 - bromopyridyl) - 3 - methyl - 2 - furanyl ketone should pay attention to the following points during use:
First, because it contains special atoms and groups, such as deuterium atoms and bromine, methyl, furan, etc., it should avoid contact with strong oxidants during operation. Strong oxidants may react violently with these groups, or cause dangerous conditions such as combustion and explosion. As the ancients said: "Water and fire are incompatible, so are strong oxygen and heterogroups."
Second, due to the complexity of its structure, it is quite sensitive to temperature and humidity. High temperature may change the molecular structure, causing it to lose its original properties; high humidity environment may cause reactions such as hydrolysis. Just as Tiangong Kaiwu pays attention to the preservation environment of various materials, this compound also needs to be stored in a cool and dry place.
Third, be sure to take protective measures during operation. Because of its unique chemical properties, it may cause irritation to the skin, eyes, respiratory tract, etc. Wear suitable protective clothing, gloves, goggles and masks to avoid contact or inhalation and damage to the body.
Fourth, when conducting chemical reactions, it is necessary to precisely control the reaction conditions. Due to the different activities of different groups in the structure, the reaction conditions are slightly deviated, and the products may be unexpected or accompanied by many side reactions. Just like ancient alchemy, if the heat is slightly improper, the medicinal pills will become waste, and the reaction of this compound also needs to be cautious.