What is the chemical structure of N- [2- (Dimethylamino) Ethyl] -N-Methylguanidine Hydroiodide?
Alas! I want to know the chemical structure of "N - [2 - (dimethylamino) ethyl] -N - methyl guanidine hydroiodide".
This compound has guanidine as its core structure. Guanidine is a nitrogen-containing organic compound with unique chemical properties. In this compound, above the guanidine group, the N atom is connected by [2 - (dimethylamino) ethyl] and methyl.
Let's talk about the [2 - (dimethylamino) ethyl] first. Ethyl is a hydrocarbon chain, and the carbon atom above it is connected by dimethylamino. The dimethylamino group is a group where the nitrogen atom is connected to two methyl groups, which has the property of electricity supply and can affect the electron cloud distribution of the molecule.
In addition, the methyl group is directly connected to the nitrogen atom of the guanidine group. And the hydroiodide is the salt formed by the organic part and the hydroiodic acid. The hydrogen ion of the hydroiodic acid is combined with the guanidine nitrogen atom, and the iodine ion balances the charge with it to form a stable ionic compound.
In this way, the chemical structure of "N - [2 - (dimethylamino) ethyl] -N - methyl guanidine hydroiodide" is clear. The particularity of its structure may endow this compound with unique physical, chemical, and biological activities, which may be useful in the fields of organic synthesis, drug development, and so on.
What are the main uses of N- [2- (Dimethylamino) Ethyl] -N-Methylguanidine Hydroiodide?
N - [2 - (dimethylamino) ethyl] - N - methylguanidine hydroiodide has a wide range of uses. In the field of medicine, it is often used as a key intermediate. Geinguanidine compounds have unique biological activities. This substance can be converted through specific reactions to produce a variety of drugs with pharmacological effects, such as innovative drugs with therapeutic effects on certain diseases, which can adjust human physiology and help health recovery.
In the chemical industry, it is also indispensable. It can participate in many organic synthesis reactions, laying the foundation for the preparation of materials with special properties. Due to its structural characteristics, it can endow materials with unique properties, such as improving the stability and solubility of materials, and then expand the application scope of materials, which has potential uses in coatings, plastics and many other aspects.
In the process of scientific research and exploration, it is an important research object. By studying its reaction mechanism and property changes, researchers deepen their understanding of the principles of organic chemistry, provide ideas for the design and synthesis of new compounds, promote the development of chemistry, or lead to more innovative research results, which have a profound impact in many fields.
What is the synthesis method of N- [2- (Dimethylamino) Ethyl] -N-Methylguanidine Hydroiodide?
To prepare N - [2 - (dimethylamino) ethyl] -N - methyl guanidine hydroiodate, the method is as follows:
First take an appropriate amount of 2 - (dimethylamino) ethylamine and place it in a clean reaction vessel. Prepare a cooling device to keep the reaction environment at a suitable low temperature, about 0 - 5 ° C. Slowly add methyl isothiocyanate dropwise to a container containing 2 - (dimethylamino) ethylamine. When adding dropwise, it is necessary to continuously stir to make the two fully contact the reaction. In this step, the two reactions are carried out according to a certain stoichiometric ratio, which is roughly 1:1.2, so that the reaction is relatively complete.
After the methyl isothiocyanate is added dropwise, keep stirring at low temperature for a period of time, about 1-2 hours (ie 2-4 hours), and it can be seen that precipitation is gradually formed in the reaction solution. This precipitation is an intermediate product, N - [2 - (dimethylamino) ethyl] -N - methyl thiourea.
Then, the temperature of the reaction system is slowly raised to room temperature, and then an appropriate amount of hydrogen iodide solution is added. The hydrogen iodide and the intermediate product continue to react. During this process, the reaction conditions need to be carefully controlled, and the temperature should not be too high to avoid side reactions. Continue to stir the reaction for several hours (about 4-6 hours). After the reaction is completed, it can be seen that the product in the solution is more abundant.
Next, the reaction solution is treated. The organic phase is extracted with a suitable organic solvent to separate the organic phase. After that, the organic phase is distilled to remove the organic solvent to obtain a crude N - [2 - (metformyl) ethyl] -N - methyl guanidine hydroiodate.
Finally, the crude product is refined. Using the method of recrystallization, select a suitable solvent, such as ethanol-water mixed solvent, and after multiple recrystallization operations, pure N - [2 - (metformyl) ethyl] -N - methyl guanidine hydroiodate salt crystals can be obtained. The whole preparation process requires fine control of the reaction conditions at each step to obtain satisfactory products.
What are the physical properties of N- [2- (Dimethylamino) Ethyl] -N-Methylguanidine Hydroiodide?
N - [2 - (dimethylamino) ethyl] - N - methylguanidine hydroiodate, this is an organic compound. It has some unique physical properties.
Looking at its shape, under room temperature and pressure, it is often in a solid state, mostly white or almost white crystalline powder, just like the first snow in winter, delicate and pure. This state is easy to store and transport, because it is relatively stable, it is not easy to quickly deteriorate or evaporate under conventional conditions.
When it comes to solubility, it shows good solubility in water, just like fish entering water and quickly melting. This property is due to the fact that its molecular structure contains polar groups, which can form hydrogen bonds and other interactions with water molecules, so it can be easily dispersed in aqueous media. Not only that, in some polar organic solvents, such as ethanol, it also has a certain solubility, but the solubility may vary depending on the properties of the solvent.
Another melting point, experimentally determined, is about a certain temperature range, and this temperature limit is of great significance for its identification and purity judgment. If the melting point deviates from the normal range, it may suggest that the purity of the compound is questionable, or it is mixed with impurities.
As for stability, it is still stable under general environmental conditions. However, it should be noted that it should not be contacted with specific substances such as strong oxidants, otherwise it will easily cause chemical reactions, causing structural changes or deterioration. Like a delicate flower, it needs to avoid the wind and rain.
The physical properties of N - [2 - (dimethylamino) ethyl] - N - methyl guanidine hydroiodate lay the foundation for its application in many fields, whether it is in chemical synthesis or pharmaceutical research and development, etc., it needs to be used rationally according to its characteristics.
What should be paid attention to when storing and using N- [2- (Dimethylamino) Ethyl] -N-Methylguanidine Hydroiodide?
N - [2 - (dimethylamino) ethyl] - N - methylguanidine hydroiodide, this is a special chemical substance. When storing and using, many key things need to be paid more attention to.
Let's talk about storage first. Because of its specific chemical activity and stability characteristics, it should be stored in a cool, dry and well-ventilated place. If the ambient temperature and humidity are too high, it may cause deterioration of the substance. In case of moisture, the hydroiodide part may absorb moisture, affecting its chemical purity and properties. And keep away from fire and heat sources, because it may be flammable or easily decomposed by heat. At the same time, it needs to be stored separately from oxidants, acids, etc., to prevent violent chemical reactions, such as oxidation-reduction reactions, from occurring, which can cause the substance to fail and even lead to safety accidents.
As for the use, the relevant operating procedures and safety guidelines must be strictly followed. When operating, it is recommended to wear appropriate protective equipment, such as protective gloves, goggles and masks. Because the substance may have irritating effects on the skin, eyes and respiratory tract, if inadvertently exposed, it may cause discomfort or even damage. During use, it is necessary to ensure that the operating environment is well ventilated and avoid inhaling its volatile gases. Furthermore, it is essential to precisely control the dosage. According to specific experimental or production needs, accurate weighing and taking are required to avoid improper dosage affecting the reaction process or product quality. After use, properly dispose of the remaining substances and related waste, follow environmental protection requirements, and do not discard them at will to prevent environmental pollution.