Medical Guanidine Hydrochloride
Aromatic sulfonic acid and its salts Sulfamic Acid Guanidine

Medical Guanidine Hydrochloride

Lingxian Chemical

Specifications

HS Code

788498

Chemical Formula CH5ClN2O
Molar Mass 95.51 g/mol
Appearance white crystalline solid
Solubility In Water highly soluble
Odor odorless
Density 1.346 g/cm³
Melting Point 181 - 183 °C
Ph Aqueous Solution around 4 - 6
Hygroscopicity hygroscopic
Stability stable under normal conditions
Chemical Formula HCl·HNC(NH2)2
Molar Mass 95.53 g/mol
Appearance white crystalline solid
Odor odorless
Solubility In Water highly soluble
Ph Of Aqueous Solution acidic
Melting Point 181 - 183 °C
Boiling Point decomposes
Density 1.354 g/cm³
Purity For Medical Use usually high purity (e.g., 99%+)
Chemical Formula CH5ClN2
Molar Mass 95.51 g/mol
Appearance white crystalline solid
Odor odorless
Solubility In Water highly soluble
Melting Point 180 - 183 °C
Boiling Point decomposes
Ph Of Aqueous Solution acidic
Density 1.354 g/cm³
Cas Number 50-01-1
Pka 13.6
Chemical Formula CH5ClN2O
Molar Mass 95.51 g/mol
Appearance White crystalline solid
Odor Odorless
Solubility In Water Highly soluble
Ph Of Aqueous Solution Acidic
Melting Point 181 - 183 °C
Boiling Point Decomposes before boiling
Density 1.354 g/cm³
Stability Stable under normal conditions
Hygroscopicity Hygroscopic
Chemical Formula HCl·HNC(NH2)2
Molar Mass 95.53 g/mol
Appearance white crystalline solid
Odor odorless
Solubility In Water highly soluble
Ph Of Aqueous Solution acidic
Melting Point 181 - 183 °C
Boiling Point decomposes
Density 1.354 g/cm³
Cas Number 50-01-1
Role In Medical Field used in protein denaturation studies, helps in purifying proteins
Chemical Formula CH5ClN2
Molar Mass 95.52 g/mol
Appearance white crystalline solid
Odor odorless
Solubility In Water highly soluble
Ph Of Aqueous Solution acidic
Melting Point 180 - 183 °C
Boiling Point decomposes
Density 1.354 g/cm³
Hygroscopicity hygroscopic
Chemical Formula CH5ClN2O
Molar Mass 95.51 g/mol
Appearance white crystalline solid
Solubility In Water highly soluble
Ph In Solution acidic
Melting Point 180 - 183 °C
Boiling Point decomposes
Density 1.354 g/cm³
Odour odourless
Stability stable under normal conditions
Hygroscopicity hygroscopic
Chemical Formula HCl·HNC(NH2)2
Molar Mass 95.53 g/mol
Appearance white crystalline solid
Odor odorless
Solubility In Water highly soluble
Ph Of Aqueous Solution acidic
Melting Point 118 - 122 °C
Boiling Point decomposes
Density 1.354 g/cm³
Stability stable under normal conditions
Chemical Formula HCl·HNC(NH2)2
Molar Mass 95.53 g/mol
Appearance white crystalline solid
Solubility In Water highly soluble
Odor odorless
Ph Of Aqueous Solution acidic
Melting Point 181 - 183 °C
Boiling Point decomposes
Density 1.354 g/cm³
Stability stable under normal conditions
Hygroscopicity hygroscopic
Chemical Formula CH5ClN2O
Molar Mass 95.51 g/mol
Appearance white crystalline solid
Odor odorless
Solubility In Water highly soluble
Ph Of Aqueous Solution acidic (around 4 in 1M solution)
Melting Point 181 - 183 °C
Boiling Point decomposes before boiling
Density 1.354 g/cm³
Hygroscopicity hygroscopic
Chemical Formula CH5ClN2
Molar Mass 95.52 g/mol
Appearance white crystalline solid
Odor odorless
Solubility In Water highly soluble
Ph Of Aqueous Solution acidic
Melting Point 181 - 183 °C
Boiling Point decomposes
Density 1.346 g/cm³
Cas Number 50-01-1
Pka Value about 13.6
Chemical Formula CH5ClN2O
Molar Mass 95.517 g/mol
Appearance white crystalline solid
Odor odorless
Solubility In Water highly soluble
Ph Of Aqueous Solution acidic
Melting Point 181 - 183 °C
Boiling Point decomposes
Density 1.354 g/cm³
Stability stable under normal conditions
Hygroscopicity hygroscopic
Chemical Formula CH5ClN2O
Molar Mass 95.51 g/mol
Appearance white crystalline solid
Odor odorless
Solubility In Water highly soluble
Melting Point 181 - 183 °C
Ph In Solution acidic
Density 1.354 g/cm³
Boiling Point decomposes
Hygroscopicity hygroscopic
Chemical Formula HCl·HNC(NH2)2
Molecular Weight 95.53 g/mol
Appearance white crystalline powder
Odor odorless
Solubility highly soluble in water
Melting Point 181 - 183 °C
Ph Of Aqueous Solution acidic
Stability stable under normal conditions
Hygroscopicity hygroscopic
Purity For Medical Use usually high purity (e.g., >99%)
Chemical Formula HCl·HNC(NH2)2
Molar Mass 95.53 g/mol
Appearance white crystalline solid
Odor odorless
Solubility In Water highly soluble
Melting Point 180 - 182 °C
Ph Of Aqueous Solution acidic
Boiling Point decomposes
Density 1.354 g/cm³
Stability stable under normal conditions
Chemical Formula CH5ClN2O
Molar Mass 95.517 g/mol
Appearance white crystalline solid
Odor odorless
Solubility In Water highly soluble
Melting Point 180 - 183 °C
Boiling Point decomposes
Density 1.354 g/cm³
Ph Of Aqueous Solution acidic
Hygroscopicity hygroscopic
Role In Medicine used to denature proteins, aids in protein refolding studies
Chemical Formula CH5ClN2O
Molar Mass 95.51 g/mol
Appearance white crystalline solid
Odor odorless
Solubility In Water highly soluble
Ph Of Aqueous Solution acidic (around 4 - 5)
Melting Point 181 - 183 °C
Boiling Point decomposes before boiling
Density 1.346 g/cm³
Stability stable under normal conditions
Hygroscopicity hygroscopic
Chemical Formula HCl·HNC(NH2)2
Molar Mass 95.53 g/mol
Appearance white crystalline solid
Odor odorless
Solubility In Water highly soluble
Ph Of Aqueous Solution acidic
Melting Point 118 - 122 °C
Boiling Point decomposes
Density 1.354 g/cm³
Hygroscopicity hygroscopic
Stability stable under normal conditions
Packing & Storage
Packing Medical Guanidine Hydrochloride: Packed in 5 - kg bags for secure storage and transport.
Storage Medical Guanidine Hydrochloride should be stored in a cool, dry, well - ventilated area. Keep it away from sources of heat, ignition, and incompatible substances like strong oxidizing agents. Store in tightly - sealed containers to prevent moisture absorption and contamination, which could affect its quality and efficacy in medical applications.
Shipping Medical Guanidine Hydrochloride is shipped in well - sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations to ensure safety during transit, with proper labeling and handling to prevent spills and contamination.
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Medical Guanidine Hydrochloride Medical Guanidine Hydrochloride Medical Guanidine Hydrochloride
General Information
Frequently Asked Questions
What are the main uses of Medical Guanidine Hydrochloride?
In medicine, guanidine hydrochloride is widely used. In medical pharmacology, it can dissolve the structure of proteins and degrade them, which is essential for analyzing the properties and functions of proteins. It can break the weak interactions between proteins, such as hydrogen bonds, hydrophobic effects, etc., so that the protein stretches, which is convenient for exploring its internal mysteries. It can help doctors understand the principle of protein pathogenesis and find a way for treating diseases.
And in biopharmaceuticals, it is a key agent. When preparing recombinant proteins, it can prevent protein misfolding, promote the formation of its correct conformation, and ensure good drug efficacy. And in the process of purifying proteins, by its power of denaturation, remove impurities and improve the purity of products, which is related to the quality and safety of drugs.
In molecular biology experiments, it is also indispensable. When extracting nucleic acid, it can break cells and nuclear membranes, release nucleic acid, inhibit nucleic acid enzyme activity, and protect the integrity of nucleic acid, so as to facilitate subsequent genetic analysis, detection, etc., and help to understand the mystery of life genetics. It is a powerful tool in the fields of medical pharmacology, pharmacy and molecular biology, helping to advance medical science and protect the health of all living beings.
Medical Guanidine Hydrochloride
Medical Guanidine Hydrochloride, known as Guanidine Hydrochloride in Chinese, is a crucial reagent in laboratory settings. Its usage methods are as follows:
In protein research, it is often employed to denature proteins. When dissolving proteins, one should dissolve Medical Guanidine Hydrochloride in an appropriate buffer solution. For instance, a common buffer like Tris - HCl buffer can be utilized. Prepare a solution with a suitable concentration of Medical Guanidine Hydrochloride, usually in the range of 4 - 8 mol/L. Then, add the protein sample into this solution. Gently stir or shake the mixture, allowing the protein to interact with the Medical Guanidine Hydrochloride. This process disrupts the non - covalent bonds within the protein, such as hydrogen bonds and hydrophobic interactions, thus unfolding the protein structure.
In nucleic acid extraction, Medical Guanidine Hydrochloride also plays an important role. It can help in lysing cells and inactivating nucleases. First, mix the sample containing cells with a solution containing Medical Guanidine Hydrochloride. The guanidine ions can break down the cell membrane and release the nucleic acids. Meanwhile, the strong chaotropic nature of Medical Guanidine Hydrochloride can inhibit the activity of nucleases, preventing the degradation of nucleic acids. After cell lysis, subsequent steps like nucleic acid precipitation and purification can be carried out.
It should be noted that when using Medical Guanidine Hydrochloride, one must pay attention to safety. It is corrosive and can cause harm to the skin and eyes. Wear appropriate protective equipment, such as gloves and goggles, during the operation. Also, ensure proper ventilation in the working area to avoid inhaling its fumes.
Medical Guanidine Hydrochloride
For medical guanidine hydrochloride, use it with caution and a lot of attention. First, it concerns its properties. Guanidine hydrochloride is a white crystal and is very soluble in water, alcohol, etc. When using it, it is necessary to check its appearance carefully. If there is a discoloration or deliquescence, it may have changed its quality and cannot be used. Second, it concerns its preservation. It needs to be placed in a cool, dry and ventilated place, away from fires and heat sources. Because it is easy to absorb moisture, heavy moisture can cause it to deteriorate and reduce its effectiveness. Third, it concerns its toxicity. Although it is for medical use, it is also toxic to a certain extent. When using, do not let the skin and eyes come into contact with it. If you accidentally touch it, rinse it with plenty of water quickly, and seek medical treatment if necessary. Fourth, it concerns its dosage. When used medically, the dosage must be accurate and follow the doctor's instructions. If used too much, it may cause adverse reactions and damage to the human body; if the dosage is insufficient, it will be difficult to achieve the expected effect. Fifth, it concerns its compatibility. Do not mix with strong oxidants and other co-stocks to prevent chemical reactions from occurring and causing dangerous conditions. In short, when using guanidine hydrochloride for medical use, all precautions must be kept in mind to ensure that it is safe and effective, and does not cause disasters.
What are the storage conditions of Medical Guanidine Hydrochloride?
The medical guanidine hydrochloride is strong and corrosive, and its storage is essential for safety and cannot be ignored.
The environment in which it is stored should be cold and dry, avoiding heat and humidity. Heat is vapor, which can easily cause the pressure of the container to rise sharply, which is dangerous; wet is deliquescence, which damages its quality and reduces its efficiency. Therefore, when choosing a cool place, place it in a well-ventilated place, the temperature should not exceed 30 degrees Celsius, and the humidity should be controlled below 60%.
Its storage must be resistant to corrosion. Glass utensils, although clearly visible, are brittle and fragile, which is not the first choice; plastic materials are not resistant to this and are discarded. The only specially made steel tank, lined with an anti-corrosion layer, can be used for this purpose. It must be tightly sealed to prevent it from communicating with external air, prevent leakage and protect the quality.
When coexisting with other things, care must be taken. Acids and alkalis, when they come into contact with them, will cause exacerbation, generate harmful gas, and form a dangerous state, so they should be separated and stored. Oxidation and reduction agents cannot be put together to avoid unexpected changes.
In addition, the storage area must be clearly marked, and its name, nature, risk and other important items must be written in order to identify them. Always prepare emergency equipment, such as neutralizing agents and leakage materials, to prevent loss. The person in charge must undergo strict training, understand the risks, and be familiar with the rules before he can perform his duties. In this way, the storage of guanidine hydrochloride for medical use is guaranteed, so that it can be prepared for medical needs without suffering.
Medical Guanidine Hydrochloride Quality Standards
"Tiangong Kaiwu" recorded that it was all kinds of skills in industry and agriculture at that time, but it did not involve Medical + Guanidine Hydrochloride (Guanidine Hydrochloride), so there is no way to answer in its format. Guanidine hydrochloride is a chemical reagent, and its Quality Standards are modern and detailed.
Usually, the Quality Standard of Guanidine Hydrochloride is related to purity. Those with high purity have few impurities, and can be used in scientific research and high-end pharmaceutical fields. The purity often needs to reach more than 99%. In addition, it is related to the content of heavy metals, which should be extremely low to prevent interference and poisoning to biological experiments or medical applications. The content of heavy metals such as lead and mercury often needs to be controlled below one part per million. In addition, drying weight loss is also an important indicator to ensure that its water content is appropriate to avoid moisture affecting its chemical properties and applications. Generally, drying weight loss is controlled within a certain range, such as 0.5%. In terms of particle size, there are corresponding requirements according to different application requirements, such as specific particle size distribution for some specific experiments or production to ensure reaction or product uniformity. And the pH value of the solution is also specified, which needs to be maintained in a suitable range to meet the chemical environmental requirements of various application scenarios.