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What is the use of [1,1 '-biphenyl] -2,2' -disulfonic acid, 4,4 '-diamino-
The uses of [1,1 '-binaphthalene] -2,2' -disulfonic acid, 4,4 '-dihydroxy-are as follows:
First, in the field of organic synthesis, [1,1' -binaphthalene] -2,2 '-disulfonic acid is often used as a chiral catalyst or ligand. Due to its unique chiral structure, it can effectively induce asymmetric synthesis reactions, prompting the reaction to selectively generate products of a specific configuration. This is of great significance in drug synthesis. Many active pharmaceutical ingredients require a specific chiral configuration to exert the best efficacy. With the help of this substance, highly selective chiral synthesis can be achieved.
Second, 4,4' -dihydroxy-related compounds are widely used in materials science. For example, it can be used as a monomer for synthesizing high-performance polymers. By polymerizing with other monomers, the polymer is endowed with properties such as good thermal stability and mechanical properties. In the preparation of special engineering plastics, the introduction of such hydroxyl-containing monomers can enhance the intermolecular force and improve the comprehensive properties of the material.
Third, in the field of analytical chemistry, [1,1 '-binaphthalene] -2,2' -disulfonic acid can be used for the separation and analysis of chiral compounds. Using its specific interaction with chiral substances, high-efficiency separation and accurate identification of chiral isomers can be achieved through chromatography and other analytical means, providing a powerful tool for studying the properties and purity of chiral compounds.
Fourth, compounds based in part on 4,4 '-dihydroxy-structures have emerged in the field of biomedicine. They may have certain biological activities, such as potential antioxidant, anti-inflammatory and other properties, providing valuable lead compounds for the development of new drugs or bioactive materials, which need to be further studied and exploited.
What are the chemical properties of [1,1 '-biphenyl] -2,2' -disulfonic acid, 4,4 '-diamino-
The chemical properties of 1,1 '-binaphthalene-2,2' -dicarboxylic acid and 4,4 '-dihydroxy are as follows:
1,1' -binaphthalene-2,2 '-dicarboxylic acid, this substance contains two carboxyl functional groups. The carboxyl group is acidic and can be neutralized with bases, such as with sodium hydroxide, to form corresponding carboxylic salts and water. Because it has two carboxyl groups, it can participate in esterification reactions. Under acid catalysis and heating conditions, it reacts with alcohols to form ester compounds. At the same time, due to the existence of the binaphthalene structure, the substance has certain spatial structure and chiral characteristics, and is widely used in the field of chiral recognition and asymmetric synthesis. It can be used as a chiral ligand or catalyst to assist asymmetric organic synthesis reactions and obtain products with specific chiral configurations.
4,4 '-dihydroxy compound, because it contains two hydroxyl functional groups, the hydroxyl group has certain activity. It can react with active metals such as sodium to replace hydrogen. Dehydration reactions can occur. Under appropriate conditions, intramolecular dehydration forms ether compounds, or intermolecular dehydration forms polyethers. Moreover, hydroxyl groups can be oxidized, and can be converted into aldehyde groups, carbonyl groups or carboxyl groups under the action of specific oxidants. At the same time, the substance can participate in the polycondensation reaction, react with diacids and other substances with bifunctional groups to form polymers, which are used in the field of materials science to prepare polyesters and other polymer materials.
In summary, 1,1 '-binaphthalene-2,2' -dicarboxylic acid mainly exhibits carboxyl-related properties and chiral-related properties, and 4,4 '-dihydroxy compounds mainly reflect various reactivity of hydroxyl groups. Due to the different functional groups contained, there are differences in chemical reactions and application directions.
What is the synthesis method of [1,1 '-biphenyl] -2,2' -disulfonic acid, 4,4 '-diamino-
The synthesis of [1,1 '-binaphthalene] -2,2' -disulfonic acid, 4,4 '-dihydroxy-is rather complicated, involving a lot of chemical knowledge and delicate steps. This is described in detail as follows:
Synthesis of [1,1' -binaphthalene] -2,2 '-disulfonic acid
The synthesis of this compound is often started with 1,1' -binaphthalene. First, the 1,1 '-binaphthalene is sulfonated in a suitable solvent under the action of sulfonating agents such as sulfuric acid. For example, dissolve the 1,1' -binaphthalene in fuming sulfuric acid and control the appropriate temperature and reaction time. The sulfur trioxide contained in fuming sulfuric acid enhances the sulfonation ability and prompts the sulfonic acid group to replace the hydrogen atom at a specific position on the naphthalene ring. During the reaction process, it is necessary to pay close attention to the temperature. If the temperature is too high, it is easy to cause excessive sulfonation, generating unnecessary multi-sulfonated products, which affects the purity of the target product. After the reaction is completed, the product is often separated and purified by means of neutralization, extraction, recrystallization, etc., to obtain pure [1,1 '-binaphthalene] -2,2' -disulfonic acid.
Synthesis of 4,4 '-dihydroxy-related compounds
1. ** Route using phenolic compounds as starting materials **: If the starting material is a suitable phenol, such as hydroquinone derivatives, the activity of phenolic hydroxyl groups can be exploited. Nucleophilic substitution reaction occurs under base catalysis by reagents such as halogenated hydrocarbons or sulfonates. The function of the base is to capture the hydrogen of the phenolic hydroxyl group, generate phenoxy anions, and enhance its nucleophilicity, which makes it easier to attack the carbon atoms of halogenated hydrocarbons or sulfonates, form carbon-oxygen bonds, and construct the basic structure of the target compound. Subsequent steps such as functional group conversion, protection, and deprotection may be required to achieve the synthesis of the final product.
2. ** Strategy through oxidation reaction **: Using a naphthalene derivative with a suitable substituent as the starting material, a hydroxyl group is introduced through oxidation reaction. For example, using a specific oxidizing agent, such as oxygen or hydrogen peroxide, in the presence of a transition metal catalyst, to oxidize a specific position of the naphthalene ring. Transition metal catalysts can activate oxidizing agents, so that oxidation reactions can selectively occur at the target site, resulting in the generation of 4,4 '-dihydroxy-related products. In this process, the choice of catalyst and the precise regulation of reaction conditions are extremely critical, which are related to the selectivity and yield of the reaction.
When synthesizing the above compounds, the experimental operation needs to be rigorous and meticulous, and the reaction conditions, including temperature, reaction time, and reactant ratio, should not be underestimated. Only in this way can high-purity target products be efficiently obtained.
[1,1 '-Biphenyl] -2,2' -disulfonic acid, 4,4 '-diamino-what are the relevant application fields
1,1 '-Binaphthalene-2,2' -disulfonic acid (1,1 '-Binaphthalene-2,2' -disulfonic acid) and 4,4 '-dihydroxy-related application fields are quite extensive. The following is based on the classical style of "Tiangong Kaiwu":
1,1' -binaphthalene-2,2 '-disulfonic acid is useful in many fields. In the field of chemical synthesis, it is often a key component of catalysts. Because of its unique molecular structure, it can guide the direction of the reaction in asymmetric synthesis reactions, making the product highly stereoselectivity. For example, in the preparation of some chiral drugs, this compound can assist in the precise synthesis of the required enantiomers, improve the efficacy of the drug, and reduce side effects.
As for 4,4 '-dihydroxyl-related substances, it also has outstanding performance in materials science. In the preparation of polymer materials, it can be used as a cross-linking agent or comonomer. With its hydroxyl activity, it can react with other monomers to form a three-dimensional network structure, enhancing the mechanical properties and thermal stability of the material. For example, when preparing high-performance engineering plastics, adding an appropriate amount of 4,4' -dihydroxyl compounds can significantly improve the strength and heat resistance of the plastic, making it widely used in automotive, aerospace and other industries that require strict material properties.
Furthermore, in the field of analysis and detection, 1,1 '-binaphthalene-2,2' -disulfonic acid is also useful. Because of its unique ability to recognize specific metal ions or organic molecules, it can be designed as a fluorescent probe or chemical sensor. By detecting the change of the optical signal after its interaction with the target, it can achieve high sensitivity and high selectivity detection of the target, which is of great value in environmental monitoring, biomedical diagnosis, etc. 4,4 '-dihydroxy-related substances can be used as indicators in some color reactions to judge the reaction process or detect the existence of specific substances according to the change of color.
What is the market outlook for [1,1 '-biphenyl] -2,2' -disulfonic acid, 4,4 '-diamino-
1. Market prospect of 1,1 '-binaphthalene-2,2' -disulfonic acid, 4,4 '-dihydroxy-
Fu 1,1' -binaphthalene-2,2 '-disulfonic acid, in the field of chemical industry, has a wide range of uses. In the preparation of catalysts, it can provide a unique environment for the reaction and help the catalytic reaction to advance efficiently. In the field of material synthesis, it can participate in the construction of materials with special structures to give materials specific properties, such as optical and electrical properties. Looking at the current market, with the vigorous development of the chemical industry, the demand for high-efficiency catalysts and special performance materials is increasing, so the market prospect of 1,1' -binaphthalene-2,2 '-disulfonic acid is quite broad, and the demand is expected to rise steadily.
As for 4,4 '-dihydroxy-like substances, they are also important in the fields of medicine and polymer materials. In pharmaceutical research and development, they may be a key intermediate, participating in the synthesis of a variety of drugs, and making great contributions to human health. In the manufacture of polymer materials, they can be used as monomers for polymerization reactions to produce high-performance polymer materials, such as high-strength and high-toughness materials. Today, the pharmaceutical industry continues to progress, and the demand for innovative drugs continues to rise; the application of polymer materials in various industries is also becoming more and more extensive. The market prospect of 4,4' -dihydroxy-related products is also optimistic, and the future development space is considerable.
In short, both of these are of great value in various self-related fields. With the continued development of various industries, the market prospects are very bright, and it is expected to usher in more development opportunities and growth space.