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What is the chemical structure of [ (1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-yl) (methyl) amino] methane sulfonate
(1) This is a structural analysis problem of an organic compound. We need to deduce its chemical structure based on the given group information.
(2) View the given group:
1. "1,5-dimethyl-3-oxo-2-benzyl-2,3-dihydro-1H-indole-4-yl", which is a complex cyclic structure part. " 1,5-Dimethyl ", indicating that there are two methyl groups connected at a specific position;" 3-oxo ", indicating that there is a carbonyl group (C = O) at the third position;" 2-benzyl ", that is, the second position is connected with a benzyl group (-CH -2 -benzene ring);" 2,3-dihydro-1H-indole ", showing that the indole ring part has hydrogen atom addition at the 2nd and 3rd positions;" 4-group ", indicating that the ring structure is a substituent as a whole.
2." (Methyl) amino ", that is, the -NH-CH 🥰 structure, is a nitrogen-containing substituent.
(3) Combine the above groups. The core of this compound is a modified indole ring structure, with methyl, benzyl, carbonyl and other groups connected at a specific position, and is connected to methyl by nitrogen atoms to form an amino structure. Its chemical structure is schematic as follows (because it is difficult to draw accurate graphics, it is replaced by text description): based on the indole ring, the 1st and 5th positions are connected to methyl; the 3rd position is carbonyl; the 2nd position is connected to benzyl; the 2nd and 3rd positions are in the dihydrogen state; the 4th position is connected to the nitrogen atom, and the nitrogen atom is then connected to the methyl group. This structure is the desired chemical structure of (5-methyl-3-oxo-2-benzyl-2,3-dihydro-1H-indole-4-yl) (methyl) aminoacetic anhydride.
What are the physical properties of [ (1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-yl) (methyl) amino] methane sulfonate
(One, five-dimethyl-three-oxo-di-benzyl-di, three-dinitrogen-monohydro-pyrazole-tetrayl) (methyl) alkenyl ketoxime ester, which is an organic compound. Its physical properties are quite characteristic, let me tell them one by one.
Looking at its morphology, under room temperature and pressure, it may be a solid crystalline substance, which is arranged in an orderly manner due to intermolecular forces. The melting point of this compound, or due to the interaction of chemical bonds and groups in the molecular structure, is in a specific temperature range. The conjugated system and functional groups in the molecule may cause it to have a certain stability.
When it comes to solubility, according to the principle of similar compatibility, it may have better solubility in organic solvents such as ethanol and acetone. Because of the molecular structure and polarity of organic solvents, it can interact with the molecules of the compound to help it disperse and dissolve. However, in water, due to the difference in molecular polarity and water, or poor solubility.
Furthermore, its density is also one of the important physical properties. Due to the different types and quantities of atoms in the molecule, the sum of atomic weights and the way of molecular stacking determine its density value. This value is relatively stable under specific conditions, providing an important basis for the identification and application of this compound.
Because of its molecular structure, there are specific unsaturated bonds and functional groups, or it has absorption properties for specific wavelengths of light. This optical property can be used as an important reference for the analysis and identification of the compound.
The above physical properties are of crucial significance in many fields such as organic synthesis and drug development, which can help researchers better understand and apply this compound.
What is the use of [ (1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-yl) (methyl) amino] methane sulfonate
(One-five, dimethyl, three, oxo, two, benzyl, two, three, dihydro, monohydro, pyrrole, four, yl) (methyl) urea propionaldehyde anhydride has a wide range of uses. In the field of medicine, it is often used as a key intermediate to synthesize many drugs. Due to its structural properties, it can participate in a variety of chemical reactions. With ingenious design and modification, it can create compounds with specific pharmacological activities, or can act on specific targets to treat diseases with precision.
In the field of materials science, this substance may be used to prepare special polymer materials. With its unique chemical structure, it can endow materials with special properties, such as enhancing material stability and improving its mechanical properties. For example, it can be integrated into the polymer system as a crosslinking agent to enhance the strength and toughness of the material by forming chemical bonds.
In the field of organic synthetic chemistry, it is an important synthetic building block, providing the possibility for the construction of complex organic molecular structures. Organic chemists can use various organic reactions to derive organic compounds with different functions and uses according to their structural characteristics, thus expanding the variety of organic compounds and laying the foundation for related research and applications.
What are the synthesis methods of [ (1,5 -dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-yl) (methyl) amino] methane sulfonate
To prepare [ (1,5-dimethyl-3-oxidized-2-benzyl-2,3-dihydro-1H-indole-4-yl) (methyl) amino] benzyl acetate, the following ancient method can be carried out.
Begin with 1,5-dimethyl-3-oxidized indole, and react it with benzyl halide under alkali catalysis to obtain 2-benzyl-1,5-dimethyl-3-oxidized indole. In this step, the reaction temperature and duration need to be controlled to prevent side reactions from occurring. The temperature should be maintained in a moderate range, and the duration depends on the reaction process.
The 2-benzyl-1,5-dimethyl-3-oxindole is treated with an appropriate reducing agent to partially reduce the 2,3-dihydro-1H-indole structure to obtain 2-benzyl-1,5-dimethyl-2,3-dihydro-1H-indole-3-ol. Be careful when selecting a reducing agent, and observe its reducing ability and selectivity to maintain the purity of the product.
Following the reaction of this alcohol with a suitable halogenated benzyl acetate in the presence of a base, the target product was obtained by nucleophilic substitution [ (1,5-dimethyl-3-oxidized-2-benzyl-2,3-dihydro-1H-indole-4-yl) (methyl) amino] benzyl acetate. The choice of solvent during the reaction is also heavy, and it needs to have good solubility to the reactants and no side reaction with the reagents.
After each step of the reaction, it is necessary to use suitable separation and purification methods, such as column chromatography, recrystallization, etc., to remove impurities and extract the purity of the product, in order to obtain high-quality [ (1,5-dimethyl-3-oxide-2-benzyl-2,3-dihydro-1H-indole-4-yl) (methyl) amino] benzyl acetate.
[ (1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-yl) (methyl) amino] methane sulfonate What are the relevant safety precautions
(Penta-dimethyl-tri-oxo-di-benzyl-diazo-monohydro-pyridine-tetrayl) (methyl) guanoxy acetic acid is a rather complex chemical substance. When using this substance, many safety precautions need to be kept in mind.
First of all, because of its chemical activity, the operation must be carried out in a well-ventilated environment, preferably in a fume hood. If operated in a closed and airless place, its volatile gaseous substances may accumulate in the air, which will not only affect the health of the experimental personnel, but also cause poisoning in severe cases.
Furthermore, when exposed to this substance, protective measures must be taken. Appropriate protective equipment should be worn, such as lab clothes, gloves and goggles. The lab clothes can prevent it from contaminating daily clothing, gloves can avoid direct contact with the skin, and goggles can protect the eyes from accidental splashing damage. It may be irritating or even corrosive to the skin, eyes and respiratory tract.
For storage, keep it in a cool, dry place away from sources of fire and oxidants. A cool and dry environment can prevent it from deteriorating due to temperature and humidity problems or causing chemical reactions, while keeping away from sources of fire and oxidants can avoid serious accidents such as fires and explosions.
In addition, it is essential to strictly follow established experimental procedures and operating procedures during operation. Do not change the reaction conditions or operation sequence at will, otherwise uncontrollable chemical reactions may occur. After use, proper disposal of the remaining substances and experimental equipment should not be ignored to prevent pollution to the environment.