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What is the main use of 1- [[bis [ (4-vinylphenyl) methyl] amino] methanesulfonic acid
The main uses of this compound are as follows.
This compound is widely used in the field of organic synthesis. First, it is often used as an important intermediate in organic synthesis. Through a series of chemical reactions, it can be used to construct many complex organic molecules with specific structures and functions. For example, when synthesizing some bioactive natural product analogs, the unique structure of this compound can be used to achieve effective synthesis of the target product through carefully designed reaction steps, providing a key starting material for new drug development and bioactive molecular research.
Second, it also has important applications in the field of materials science. It can be used as a functional monomer to participate in the polymerization reaction, so as to prepare polymer materials with special properties. These materials may have unique electrical, optical or mechanical properties, and are expected to be applied to new photoelectric materials, high-performance engineering plastics, etc., injecting new vitality into the development of materials science.
Third, in terms of medicinal chemistry, due to its special chemical structure, it may have potential pharmacological activity. By modifying and modifying its structure, it is expected to develop new types of drugs for the treatment of various diseases and contribute to human health.
In summary, di [ (4-ethylbenzyl) methyl] iminoacetic acid plays an important role in many fields such as organic synthesis, materials science, and medicinal chemistry, and is of great significance for promoting the development of related fields.
What are the physicochemical properties of 1- [[bis [ (4-vinylphenyl) methyl] amino] methanesulfonic acid
Eh! The chemical properties of Ximing (1- [[ (4-ethylphenyl) methyl] amino] benzoic acid, and described in ancient Chinese, are as follows.
Among this compound, it has a certain degree of melting and boiling. The force of the molecule has its own law, so that its melting and boiling have a certain degree. However, in order to know precisely, it is still necessary to know. Its solubility can be investigated. In the solubility, such as in water, or due to poor solubility, the solubility is poor. And in the solubility, such as ethanol, ethyl ether, or because of its aryl and other groups in the mixture, there is a certain solubility, and the force of the molecules that are soluble is appropriate to disperse them.
Its chemical properties should not be ignored. On benzene, due to the shadow of the substituent, the density distribution of benzene is changed. In case of benzene, or it can be replaced on benzene. And its amino part, with certain properties, can cause acid to react and form a compound. The carboxyl group is acidic and can react, such as oxidation, etc., can form a phase of water.
And because it contains many groups, different groups may have mutual effects. The rationality of this compound is due to its dense phase. To understand it, it is necessary to explore and deduce it in order to get the whole picture.
What are the precautions for 1- [[bis [ (4-vinylphenyl) methyl] amino] methanesulfonic acid in the production process?
In the production process of acetic acid for the production of bis [ (4-ethoxybenzyl) methyl] nitrosamines, many matters need to be paid more attention.
Quality of the first raw materials. Raw materials such as 4-ethoxybenzyl and methyl must reach a very high purity. Impurities are mixed, which will inevitably cause reaction deviations and impure products. If the raw materials contain trace moisture or cause the reaction rate to drop sharply, it is more likely to trigger side reactions and produce impurities, which will seriously affect the quality of the product.
Control of reaction conditions is crucial. In terms of temperature, it should be strictly maintained within a specific range. If the temperature is too low, the reaction will be slow or even stagnant; if the temperature is too high, the reaction will be overreacted, or the raw materials will decompose, and unnecessary by-products may also Taking a common organic reaction as an example, if the temperature deviation is several degrees, the yield and purity of the product will be very different. Pressure cannot be ignored. Appropriate pressure ensures the smooth progress of the reaction. Improper pressure or change the direction of the reaction, and the expected product cannot be obtained.
The use of catalysts should be cautious. Appropriate catalysts can greatly improve the reaction efficiency, but the dosage must be accurate. Too little, the catalytic effect is not good; too much, or cause other side reactions. And the catalyst activity is also affected by many factors, such as the pH of the reaction environment, temperature changes, etc., all need to be paid close attention.
Cleanliness and material selection of reaction equipment are also critical. Unclean equipment, residual impurities mixed into the reaction system, interfere with the reaction. If the material is not resistant to corrosion and reacts with the reactants or products, it will not only damage the equipment, but also cause product pollution.
The separation and purification of the product should not be underestimated. After the reaction, the product is often mixed with impurities such as unreacted raw materials and by-products, and it is necessary to choose a suitable method for separation and purification. Extraction, distillation, crystallization and other methods have their own applicable scenarios. Improper selection makes it difficult to obtain high-purity products.
In the production process, the quality of raw materials, reaction conditions, catalysts, reaction equipment and product separation and purification all need to be carefully controlled to ensure the smooth production of acetic acid for the production of bis [ (4-ethoxybenzyl) methyl] nitrosamines and obtain high-quality products.
What is the approximate market price of 1- [[bis [ (4-vinylphenyl) methyl] amino] methanesulfonic acid
Today there is di [ (4-ethoxybenzyl) methyl] aminobenzoic acid. What is the market price? The price of this drug in the market often varies depending on the quality, the amount of supply, and the region where it is sold.
If it is normal, its price per gram may be between tens and hundreds of gold. For those with excellent quality and difficult preparation, the price will tend to be higher; for those with abundant mass production and easier preparation, the price may be slightly lower. And in different places, due to different taxes and logistics costs, the price varies.
However, if you want to know the exact price, you should consult the drug store merchants or visit the drug trading platform to obtain it. Its price fluctuations are difficult to determine, and can only be deduced from common sense.
What are the synthesis methods of 1- [[bis [ (4-vinylphenyl) methyl] amino] methanesulfonic acid
To prepare bis [ (4-ethylbenzyl) methyl] sulfoxide, the following methods can be used.
First, 4-ethylbenzyl chloride and sodium methyl mercaptan are used as starting materials. The nucleophilic substitution reaction of 4-ethylbenzyl chloride and sodium methyl mercaptan is carried out under mild heating and stirring conditions. The sulfur atom of sodium methyl mercaptan is nucleophilic and can attack the benzyl carbon of 4-ethylbenzyl chloride. The chloride ions leave to form (4-ethylbenzyl) methyl sulfide. After the reaction is completed, the product is purified by extraction, distillation and other methods. Then, (4-ethylbenzyl) methyl sulfide is oxidized with an appropriate oxidant, such as m-chloroperoxybenzoic acid (m-CPBA). The selective oxidation of the sulfide to sulfoxide can be controlled by controlling the amount of oxidant and the reaction temperature. The target product is di [ (4-ethylbenzyl) methyl] sulfoxide, which is purified by column chromatography.
Second, starting from 4-ethylbenzaldehyde. First, 4-ethylbenzyl alcohol derivative is obtained by reacting with Grignard's reagent magnesium methyl bromide. The alcohol is treated with a chlorination reagent such as dichlorosulfoxide and converted to 4-ethylbenzyl chloride. The next step is the same as method 1, and reacts with sodium methyl mercaptan to form thioether, which is then oxidized to sulfoxide.
Third, the phase transfer catalysis method is used. The 4-ethylbenzyl chloride is reacted with methyl mercaptan in the presence of a phase transfer catalyst, such as tetrabutylammonium bromide, in an water-organic solvent two-phase system to form thioether. The phase transfer catalyst can transfer the ionic reactants between the two phases to promote the reaction. The subsequent oxidation step is the same as before, and di[ (4-ethylbenzyl) methyl] sulfoxide is oxidized and purified. Each method has its own advantages and disadvantages, and the actual operation should be based on factors such as the availability of raw materials, cost, yield and product purity.