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1-Cyclopropyl-6-Fluoro-7-[(1S,4S)-5-Methyl-2,5-Diazabicyclo[2.2.1]Hept-2-Yl]-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid Methanesulfonate (1:1)

    Specifications

    HS Code

    445271

    Chemical Name 1-Cyclopropyl-6-Fluoro-7-[(1S,4S)-5-Methyl-2,5-Diazabicyclo[2.2.1]Hept-2-Yl]-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid Methanesulfonate (1:1)

    As an accredited 1-Cyclopropyl-6-Fluoro-7-[(1S,4S)-5-Methyl-2,5-Diazabicyclo[2.2.1]Hept-2-Yl]-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid Methanesulfonate (1:1) factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing One 25 - gram pack of 1 - Cyclopropyl - 6 - Fluoro...Methanesulfonate (1:1) chemical.
    Storage Store "1 - Cyclopropyl - 6 - Fluoro - 7 - [(1S,4S)-5 - Methyl - 2,5 - Diazabicyclo[2.2.1]Hept - 2 - Yl]-4 - Oxo - 1,4 - Dihydroquinoline - 3 - Carboxylic Acid Methanesulfonate (1:1)" in a cool, dry place protected from light. Keep it in a well - sealed container to prevent moisture ingress and potential degradation. Avoid storing near incompatible substances.
    Shipping The chemical "1-Cyclopropyl-6 - Fluoro-7-[(1S,4S)-5 - Methyl-2,5 - Diazabicyclo[2.2.1]Hept - 2 - Yl]-4 - Oxo-1,4 - Dihydroquinoline - 3 - Carboxylic Acid Methanesulfonate (1:1)" will be shipped in secure, sealed containers, following all hazardous chemical shipping regulations to ensure safe transit.
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    Competitive 1-Cyclopropyl-6-Fluoro-7-[(1S,4S)-5-Methyl-2,5-Diazabicyclo[2.2.1]Hept-2-Yl]-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid Methanesulfonate (1:1) prices that fit your budget—flexible terms and customized quotes for every order.

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    1-Cyclopropyl-6-Fluoro-7-[(1S,4S)-5-Methyl-2,5-Diazabicyclo[2.2.1]Hept-2-Yl]-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid Methanesulfonate (1:1)
    General Information
    Historical Development
    1 - Cyclopropyl - 6 - Fluoro - 7 - [ (1S, 4S) - 5 - Methyl - 2,5 - Diazabicyclo [2.2.1] Hept - 2 - Yl] - 4 - Oxo - 1,4 - Dihydroquinoline - 3 - Carboxylic Acid Methanesulfonate (1:1) This product, following the development of its history, has never been seen in the past. However, the way of chemistry, many researchers. At the beginning, scholars in the laboratory, after repeated experiments, to explore the methods of various reactions. From the basic raw materials, according to the principles of chemistry, to find the way of synthesis. Although repeated obstacles, or the reaction is not as expected, or the product is not pure. However, everyone was not discouraged and continued to improve. With the advance of technology, the instruments became more refined and the analysis became more accurate. After long-term grinding, the synthesis method became better and better, and finally this product was obtained. Its development in the history of chemistry is the fruit of everyone's unremitting research, and it also adds a new chapter to the field of chemistry.
    Product Overview
    There is now a product named 1 - Cyclopropyl - 6 - Fluoro - 7 - [ (1S, 4S) -5 - Methyl - 2,5 - Diazabicyclo [2.2.1] Hept - 2 - Yl] -4 - Oxo - 1,4 - Dihydroquinoline - 3 - Carboxylic Acid Methanesulfonate (1:1). This is the key object of chemical research. Its unique structure is composed of cyclopropyl, fluorine atom, specific bicyclic structure and quinoline carboxylic acid part, combined with methanesulfonic acid in a ratio of 1:1. In the research, the investigation of the properties of this compound is of great significance, and the analysis of its structure helps to clarify its reactivity and characteristics, paving the way for subsequent applications in drug development, materials science, and other fields, or playing a key role in the creation of new drugs, which is of great significance for promoting the development of chemistry-related fields.
    Physical & Chemical Properties
    1 - Cyclopropyl - 6 - Fluoro - 7 - [ (1S, 4S) - 5 - Methyl - 2,5 - Diazabicyclo [2.2.1] Hept - 2 - Yl] - 4 - Oxo - 1,4 - Dihydroquinoline - 3 - Carboxylic Acid Methanesulfonate (1:1) The physicochemical properties of this product are crucial. From the perspective of physical properties, it may have a specific form, such as crystalline state, bright or dark color, depending on its purity and quality. Its solubility cannot be ignored, and it varies in various solvents, or is easily soluble in water, or is pro-organic, which is related to its dispersion and application in different environments. When it comes to chemical properties, the activity of functional groups in its structure determines its tendency to participate in chemical reactions. Cyclopropyl, fluorine atoms and other structures give it unique chemical activities, or can undergo substitution, addition and other reactions, which are of great significance in the synthesis and application fields, and are related to the preparation and derivation of this product.
    Technical Specifications & Labeling
    There is a product today, named 1 - Cyclopropyl - 6 - Fluoro - 7 - [ (1S, 4S) -5 - Methyl - 2,5 - Diazabicyclo [2.2.1] Hept - 2 - Yl] -4 - Oxo - 1,4 - Dihydroquinoline - 3 - Carboxylic Acid Methanesulfonate (1:1). Its technical specifications and identification (product parameters) are the most critical.
    Looking at this product, the technical specifications need to show that its composition and distribution ratio are accurate, the synthesis steps are rigorous and orderly, and all links are interlocked, which cannot be wrong. From the selection of raw materials, it is necessary to seek high quality, without any impurities mixed. To the reaction conditions, temperature, pressure, etc. need to be carefully controlled in order to achieve its optimum state.
    In terms of identification, product parameters should be clear and clear, from chemical structure characterization to physical properties labeling, such as color and morphology, all must be accurate. In this way, when this product is applied, everyone can use it properly according to its technical specifications and labels (product parameters), and play its due effect.
    Preparation Method
    There is a method for preparing 1 - Cyclopropyl - 6 - Fluoro - 7 - [ (1S, 4S) -5 - Methyl - 2,5 - Diazabicyclo [2.2.1] Hept - 2 - Yl] -4 - Oxo - 1,4 - Dihydroquinoline - 3 - Carboxylic Acid Methanesulfonate (1:1), which is related to the raw materials and production process, reaction steps, and catalytic mechanism.
    Prepare all kinds of raw materials first and mix them according to a specific ratio. In a suitable reactor, control the precise temperature and pressure to make it react. The first step of the reaction requires a certain temperature range. When it is maintained, the raw materials are fully integrated and their chemical changes are promoted.
    The second step of the reaction is adjusted with an appropriate catalyst. The mechanism of catalysis is to reduce the energy barrier of the reaction and accelerate the reaction process. Close observation of the reaction state, timely fine-tuning of the conditions, to ensure the smooth reaction. After multiple steps of reaction and refining process, this product can be obtained. This preparation method requires care step by step to obtain a good product.
    Chemical Reactions & Modifications
    Now there are 1 - Cyclopropyl - 6 - Fluoro - 7 - [ (1S, 4S) -5 - Methyl - 2,5 - Diazabicyclo [2.2.1] Hept - 2 - Yl] -4 - Oxo - 1,4 - Dihydroquinoline - 3 - Carboxylic Acid Methanesulfonate (1:1) This compound is very important for the study of its transformation and modification.
    The observation of its chemical reaction, or the appearance of nucleophilic substitution, the interaction of various groups in the molecule, such as cyclopropyl, fluorine atoms, etc., all affect the reaction path. If you want to change its properties, you can start at the activity check point. For example, modifying the nitrogen-containing heterocyclic part may change its pharmacological activity.
    The reaction should be related to the modification road, and there are many thorns. The reaction conditions, temperature, solvent, catalyst, etc. need to be carefully considered, all of which are related to success or failure. And after modification, the properties and stability of the product also need to be carefully studied. Only by careful research and deep thinking can we obtain the mystery, so that this compound can be used in the fields of medicine and other fields to develop its capabilities, benefiting everyone.
    Synonyms & Product Names
    A chemical substance named 1 - Cyclopropyl - 6 - Fluoro - 7 - [ (1S, 4S) - 5 - Methyl - 2,5 - Diazabicyclo [2.2.1] Hept - 2 - Yl] - 4 - Oxo - 1,4 - Dihydroquinoline - 3 - Carboxylic Acid Methanesulfonate (1:1). In my field of chemical research, it is common to see more than one thing. This substance also has its nickname, its synonyms and trade names, although the expressions are different, they all refer to the same thing. The names vary depending on the origin or the use. However, we researchers should understand that its essence is the same, not confused by its name. In the study, accurately identify this thing, the name is changeable, and we can also explore its nature and study its use, so as to reach the depth of the study, so as not to misunderstand the research path due to the difference in name.
    Safety & Operational Standards
    1 - Cyclopropyl - 6 - Fluoro - 7 - [ (1S, 4S) -5 - Methyl - 2,5 - Diazabicyclo [2.2.1] Hept - 2 - Yl] -4 - Oxo - 1,4 - Dihydroquinoline - 3 - Carboxylic Acid Methanesulfonate (1:1) is an important chemical synthesis product. During its experiment and application, safety and operating practices are of paramount importance.
    Anyone involved in the study of this substance must be familiar with various latent risks. This substance may be chemically active and must strictly follow protective methods when exposed. At the operation site, protective equipment such as special gloves, goggles and protective clothing should be complete and available at any time. Personnel must ensure that the protective equipment is worn correctly to prevent direct contact with the substance and damage to the skin and eyes.
    Furthermore, the operating specifications cannot be ignored. The experimental operation should be carried out in a well-ventilated ring to avoid the accumulation of harmful gases. When taking the substance, weigh it accurately, operate according to the established process, and do not change the steps without authorization. After use, properly dispose of the remaining materials and waste, and do not discard it at will to prevent pollution to the environment.
    Storage should be placed in a dry, cool and away from sources of ignition and incompatible substances. Strictly control storage conditions and regularly check storage facilities to ensure that the stability of the substance is not affected.
    Only by strictly adhering to safety and operating standards can the research, production and application of 1 - Cyclopropyl - 6 - Fluoro - 7 - [ (1S, 4S) -5 - Methyl - 2,5 - Diazabicyclo [2.2.1] Hept - 2 - Yl] -4 - Oxo - 1,4 - Dihydroquinoline - 3 - Carboxylic Acid Methanesulfonate (1:1) be ensured smoothly to ensure personnel safety and environmental safety.
    Application Area
    Ah, there is a thing today, named 1 - Cyclopropyl - 6 - Fluoro - 7 - [ (1S, 4S) -5 - Methyl - 2,5 - Diazabicyclo [2.2.1] Hept - 2 - Yl] -4 - Oxo - 1,4 - Dihydroquinoline - 3 - Carboxylic Acid Methanesulfonate (1:1). The application field of this substance is quite critical. It is in the field of medicine and can treat various diseases. With its unique chemical conformation, it can accurately act on the body, adjust the imbalance of the body, and remove the disturbance of disease and pain. In the field of scientific research, it can be used to study the basis of new pharmaceuticals, help researchers explore the mechanism of drug action, and expand the new realm of medicine. And it can also be used in chemical production, or can be used as a raw material for special materials, contributing to industrial progress. Its wide application is waiting for our generation to explore in depth, so as to do its best to benefit the world.
    Research & Development
    There is a product named 1 - Cyclopropyl - 6 - Fluoro - 7 - [ (1S, 4S) -5 - Methyl - 2,5 - Diazabicyclo [2.2.1] Hept - 2 - Yl] -4 - Oxo - 1,4 - Dihydroquinoline - 3 - Carboxylic Acid Methanesulfonate (1:1). As a chemical researcher, I often study the development of this product.
    The development of this product involves many things. From the choice of raw materials to the control of the reaction, all need to be cautious. Whether the raw material is pure or not affects the quality of the product; the reaction temperature, time and other conditions also affect its formation. The road of research and development is full of difficulties, such as the low reaction yield and the removal of impurities. However, we have worked tirelessly to optimize the process after repeated experiments.
    Hope this research will make progress, make this product better, develop its strength in related fields, add luster to the industry, promote the progress of chemical research and development, and promote the prosperity of its field.
    Toxicity Research
    I have been studying in sequence for years, and now I focus on 1 - Cyclopropyl - 6 - Fluoro - 7 - [ (1S, 4S) -5 - Methyl - 2,5 - Diazabicyclo [2.2.1] Hept - 2 - Yl] -4 - Oxo - 1,4 - Dihydroquinoline - 3 - Carboxylic Acid Methanesulfonate (1:1) Toxicity studies of this compound. This compound has a specific structure and may have applications in the fields of medicine and chemical industry, but its toxicity is unknown.
    I have checked the ancient books and used the ancient method to take an appropriate amount of this substance and apply it to insects, pikas and the like. Observe its diet, behavior, and changes in demeanor. Over time and years, it has been recorded in detail. If the insects are sluggish and the pika is uncomfortable, it is a sign of toxicity.
    The study of toxicity is related to the health of living beings, and it is also the basis for the use of things. I will do it diligently, analyze the results in detail, and hope that the depth of toxicity of this thing will be revealed, and it will be a lesson for those who use this thing in future generations. Avoid disasters when they are not germinated, and use their long-term benefits to avoid their harm.
    Future Prospects
    Husband 1 - Cyclopropyl - 6 - Fluoro - 7 - [ (1S, 4S) -5 - Methyl - 2,5 - Diazabicyclo [2.2.1] Hept - 2 - Yl] -4 - Oxo - 1,4 - Dihydroquinoline - 3 - Carboxylic Acid Methanesulfonate (1:1) This product is an extraordinary future prospect in my chemical research. Its structure is exquisite, fusing several unique groups, like a natural structure.
    Looking at the past, the research of chemical substances is for the well-being of mankind. This product is also expected to follow this path and shine in the field of medicine. It may be able to cure various diseases and relieve suffering for patients. Its unique structure may act precisely on the focus of the disease to achieve efficient treatment.
    And its synthesis method, if it can be further refined and the cost can be reduced, it will definitely be widely used in the world and benefit everyone. We should study it diligently and look forward to the future, so that it can greatly develop its capabilities, contribute to the progress of human health and science and technology, and live up to the mission of scientific research and achieve unfinished great things.
    Where to Buy 1-Cyclopropyl-6-Fluoro-7-[(1S,4S)-5-Methyl-2,5-Diazabicyclo[2.2.1]Hept-2-Yl]-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid Methanesulfonate (1:1) in China?
    As a trusted 1-Cyclopropyl-6-Fluoro-7-[(1S,4S)-5-Methyl-2,5-Diazabicyclo[2.2.1]Hept-2-Yl]-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid Methanesulfonate (1:1) manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1-Cyclopropyl-6-Fluoro-7-[(1S,4S)-5-Methyl-2,5-Diazabicyclo[2.2.1]Hept-2-Yl]-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid Methanesulfonate (1:1) supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    1-Cyclopropyl-6-Fluoro-7- [ (1S, 4S) -5-Methyl-2,5-Diazabicyclo [2.2.1] Hept-2-Yl] -4-Oxo-1, 4-Dihydroquinoline-3-Carboxylic Acid Methanesulfonate (1:1) What is the main effect of
    1-Cyclopropyl-6-fluoro-7- [ (1S, 4S) -5-methyl-2,5-diazabicyclo [2.2.1] heptyl-2-yl] -4-oxo-1,4-dihydroquinoline-3-carboxylic acid methanesulfonate (1:1), this is the name of the chemical profession, its common name is often called levofloxacin mesylate.
    Levofloxacin mesylate has antibacterial effect and is widely used in medical practice. The drug can prevent the growth of pathogens and prevent their reproduction. This drug has a wide range of antibacterial, such as Gram-positive bacteria and Gram-negative bacteria, which are all in its inhibition. Gram-positive bacteria such as Streptococcus pneumoniae and Staphylococcus aureus, and Gram-negative bacteria such as Escherichia coli and Klebsiella pneumoniae are all restrained by this drug.
    Clinically, levofloxacin mesylate can treat a variety of infections. Respiratory system infections, such as pneumonia and bronchitis, can be taken to relieve symptoms and help patients recover; urinary system infections, such as cystitis and pyelonephritis, can also be cured; intestinal infections, such as bacterial dysentery, can also be cured. Because of the disease caused by bacteria, this medicine can directly attack the key points of the bacteria, break its structure and metabolism, and therefore treat the disease.
    When using medication, follow the doctor's advice, and determine the dose and course of treatment according to the condition and individual differences. In this way, the best curative effect can be obtained and adverse reactions of the drug can be avoided.
    What are the side effects of 1-Cyclopropyl-6-Fluoro-7- [ (1S, 4S) -5-Methyl-2,5-Diazabicyclo [2.2.1] Hept-2-Yl] -4-Oxo-1, 4-Dihydroquinoline-3-Carboxylic Acid Methanesulfonate (1:1)
    1-Cyclopropyl-6-fluoro-7- [ (1S, 4S) -5-methyl-2,5-diazabicyclo [2.2.1] heptyl-2-yl] -4-oxo-1,4-dihydroquinoline-3-carboxylic acid methanesulfonate (1:1), although this medicine has therapeutic effect, it also has various side effects.
    It may disturb the stomach and intestines, causing nausea, vomiting, abdominal pain, and diarrhea. People with weak spleen and stomach are especially susceptible to this damage when they take it. They have trouble eating and are getting tired.
    It also affects the central nervous system, which can cause dizziness, headache, insomnia, irritability, and even convulsions. People's mental state is thus confused, and they are in a trance during the day, and it is difficult to sleep at night.
    It may also involve the liver and kidney. The drainage of the liver and the function of the kidney to store sperm may be damaged, the source of biochemistry is hindered, and the poison and evil are difficult to discharge, which is not good for the body.
    And this drug may affect bone development. Children, pregnant women, and nursing mothers should use it with caution, for fear of damage to the fetus and larvae, and the future. When taking medication, doctors need to carefully observe the patient's body, weigh the pros and cons, and handle it cautiously in order to ensure the patient's well-being and avoid all side effects.
    1-Cyclopropyl-6-Fluoro-7- [ (1S, 4S) -5-Methyl-2,5-Diazabicyclo [2.2.1] Hept-2-Yl] -4-Oxo-1, 4-Dihydroquinoline-3-Carboxylic Acid Methanesulfonate (1:1) What are the applicable populations?
    1-Cyclopropyl-6-fluoro-7- [ (1S, 4S) -5-methyl-2,5-diazabicyclo [2.2.1] heptyl-2-yl] -4-oxo-1,4-dihydroquinoline-3-carboxylic acid methanesulfonate (1:1), this is a rather complex chemical drug name. Its applicable population is as follows:
    This drug is mostly used for patients with specific bacterial infections. Gaiyin This drug has a unique chemical structure and can inhibit or kill the physiological process of specific bacteria. In people with respiratory tract infections caused by bacteria, such as pneumonia, bronchitis, etc., if the pathogen is determined to be sensitive to it after diagnosis, this drug may be effective.
    People with intestinal bacterial infections, such as diarrhea and enteritis caused by specific bacteria, may also be suitable. If the bacteria are sensitive to the target of action of the drug, after the drug enters the human body, it can interfere with the metabolism and reproduction of bacteria through a series of complex biochemical reactions, thereby alleviating the patient's condition.
    Patients with urinary tract bacterial infections, such as urethritis, cystitis, etc., if the characteristics of the pathogenic bacteria fit the mechanism of action of this drug, this drug is also expected to become a therapeutic choice.
    However, it should be understood that not all patients with bacterial infections are suitable. Before medication, it is necessary to undergo detailed investigation by professional physicians, through laboratory testing, to clarify the type of bacteria and drug susceptibility, in order to accurately determine whether the patient is suitable for the use of this 1-cyclopropyl-6-fluoro-7- [ (1S, 4S) - 5-methyl-2,5-diazabicyclo [2.2.1] heptyl-2-yl] - 4-oxo-1,4-dihydroquinoline-3-carboxylic acid methanesulfonate (1:1) to ensure the safety and effectiveness of medication.
    How to use 1-Cyclopropyl-6-Fluoro-7- [ (1S, 4S) -5-Methyl-2,5-Diazabicyclo [2.2.1] Hept-2-Yl] -4-Oxo-1, 4-Dihydroquinoline-3-Carboxylic Acid Methanesulfonate (1:1)
    1-Cyclopropyl-6-fluoro-7- [ (1S, 4S) -5-methyl-2,5-diazabicyclo [2.2.1] heptyl-2-yl] -4-oxo-1,4-dihydroquinoline-3-carboxylic acid methanesulfonate (1:1), this is a good medicine. Its usage is quite particular, and it needs to be administered cautiously according to the disease and the doctor's advice.
    If used to treat common infections, adults are mostly given orally, and the dosage is often given twice a day. Each dose varies depending on the severity of the infection. In mild cases, only a small dose is required to slowly disperse the disease; in severe cases, the dosage needs to be increased in order to quickly contain the disease.
    However, if it is a severe infection, in addition to oral administration, it may be necessary to supplement the method of intravenous infusion to make the drug reach the hospital faster and enhance the efficacy. During the medication, the doctor must carefully observe the patient's reaction to see if there are any discomforts, such as gastrointestinal diseases, nausea, vomiting, abdominal pain, etc.; or skin changes, itching, and rash. If such abnormalities are seen, the method or dose of medication should be adjusted according to the situation.
    Children should be especially cautious when taking medication, and the dose must be carefully calculated according to their weight, age, etc., in case the medication is too much or not enough. Cover the children's viscera is delicate, and the medication is slightly poor, which may damage the righteousness. And when taking medication, you should also pay attention to their diet and daily life to help them recover their righteousness, so as to achieve the best therapeutic effect, so that the patient can recover as soon as possible and regain health.
    1-Cyclopropyl-6-Fluoro-7- [ (1S, 4S) -5-Methyl-2,5-Diazabicyclo [2.2.1] Hept-2-Yl] -4-Oxo-1, 4-Dihydroquinoline-3-Carboxylic Acid Methanesulfonate (1:1) Interact with other drugs
    Fu 1-cyclopropyl-6-fluoro-7- [ (1S, 4S) -5-methyl-2,5-diazabicyclo [2.2.1] heptyl-2-yl] -4-oxo-1,4-dihydroquinoline-3-carboxylic acid methanesulfonate (1:1), this is a specific chemical substance. Whether it will interact with other drugs needs to be investigated in detail.
    The principle of drug interaction is that when the drugs are combined, they may be produced due to similarities and differences in pharmacological mechanisms and changes in pharmacokinetics. If this chemical is used in combination with other drugs, first, from a pharmacological point of view, or acting on the same receptors, channels or signaling pathways, the drug effects will be superimposed or antagonized. For example, if other drugs also act on similar antibacterial targets, the combination or enhancement of antibacterial efficacy may also lead to the intensification of adverse reactions; if they act on opposing targets, they may cancel each other's efficacy.
    Second, from the pharmacokinetic point of view, the absorption, distribution, metabolism and excretion of drugs can be affected. If other drugs change the gastrointestinal environment, or affect the absorption rate and degree of this substance; in the distribution process, if combined with a drug with strong binding force of plasma protein, or cause its free drug concentration to change, it will affect the drug efficacy; metabolically, if other drugs affect the activity of liver drug enzymes, the metabolic rate of this substance will change, or accumulate poisoning, or the drug efficacy will be reduced; excretion, if other drugs affect the excretion function of the kidneys, it will also cause the amount of drugs in the body to be unbalanced.
    To determine the specific interaction situation between it and other drugs, it is still necessary to rely on detailed experimental research and clinical observation, and cannot be speculated. It must be strictly investigated before the advantages and disadvantages of its combination with various drugs can be understood, which is a lesson for clinical use.