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What is the chemical structure of 1-Cyclopropyl-6-Fluoro-8-Methoxy-7- (3-Methylpiperazin-1-Yl) -4-Oxo-1, 4-Dihydroquinoline-3-Carboxylic Acid Methanesulfonate (1:1)?
This is the chemical structure analysis of 1-cyclopropyl-6-fluoro-8-methoxy-7- (3-methylpiperazine-1-yl) -4-oxo-1,4-dihydroquinoline-3-carboxylic acid methanesulfonate (1:1).
According to its name, this compound is derived from the quinoline parent nucleus. On the quinoline ring, there is a cyclopropyl group at the 1st position, a fluorine atom at the 6th position, a methoxy group at the 8th position, a 3-methylpiperazine-1-group at the 7th position, an oxo group at the 4th position, and a carboxyl group at the 3rd position. This carboxyl group and methanesulfonic acid form a salt in a 1:1 ratio.
The quinoline ring has a conjugated system, providing a stable chemical structure. The cyclopropyl group at the 1st position is a small cycloalkyl group. Due to ring tension, it affects the molecular space conformation and electron cloud distribution, or changes the physical and chemical properties and biological activities of the compound. The fluorine atom at the 6th position has strong electronegativity, which can affect the electron cloud density of surrounding atoms through induction effects. In drug design, it often The 8-position methoxy power supply affects the electron cloud density distribution of the quinoline ring, or affects the reactivity and biological activity of the compound. The 7-position 3-methylpiperazine-1-group is a nitrogen-containing heterocycle, which is basic and can interact with specific parts of biological targets, such as the formation of hydrogen bonds, ionic bonds, etc., which is essential for the pharmacological activity of the compound. The 4-position oxo group makes the quinoline ring carbonyl, which can participate in a variety of chemical reactions, and also affects molecular polarity and hydrophilicity. The 3-position carboxyl group forms a salt of methanesulfonic acid, which improves the water solubility of the compound and is conducive to its absorption, distribution and metabolism in the
The chemical structure of this compound and the interaction of various substituents jointly determine its physicochemical properties and biological activities, which are of great significance in the fields of drug development and other fields.
What are the main uses of 1-Cyclopropyl-6-Fluoro-8-Methoxy-7- (3-Methylpiperazin-1-Yl) -4-Oxo-1, 4-Dihydroquinoline-3-Carboxylic Acid Methanesulfonate (1:1)?
1-Cyclopropyl-6-fluoro-8-methoxy-7- (3-methylpiperazine-1-yl) -4-oxo-1,4-dihydroquinoline-3-carboxylic acid methanesulfonate (1:1), this is the name of the chemical substance, and its use is quite extensive.
In the field of medicine, it is often used as a key component of antibacterial drugs. This chemical can inhibit or kill many bacteria, because it can act on specific bacterial targets, interfere with the normal physiological activities of bacteria, and then hinder their growth and reproduction. Clinically, it is mostly used to treat diseases caused by various bacterial infections, such as respiratory tract infections, including pneumonia, bronchitis, etc., which can effectively relieve symptoms and help patients recover; urinary tract infections, which can clear bacteria in the urinary system and relieve patients' pain; intestinal infections, which can restore the normal balance of bacteria in the intestines and relieve symptoms such as diarrhea and abdominal pain.
In addition, this substance also plays an important role in the process of drug development. Researchers often conduct in-depth research on it. Through structural modification and optimization, they hope to obtain new antimicrobial drugs with stronger antimicrobial activity and fewer side effects to deal with the increasingly serious problem of bacterial resistance and meet more needs for clinical treatment.
In the field of chemical synthesis, this substance, as a key intermediate, can provide the possibility for the synthesis of other complex organic compounds. With its unique chemical structure, it can be combined with other compounds through specific chemical reactions to construct organic molecules with novel structures and unique functions, promoting the continuous development of organic synthesis chemistry.
What is the production process for 1-Cyclopropyl-6-Fluoro-8-Methoxy-7- (3-Methylpiperazin-1-Yl) -4-Oxo-1, 4-Dihydroquinoline-3-Carboxylic Acid Methanesulfonate (1:1)?
1-Cyclopropyl-6-fluoro-8-methoxy-7- (3-methylpiperazine-1-yl) -4-oxo-1,4-dihydroquinoline-3-carboxylic acid methanesulfonate (1:1), this is a key compound in the field of pharmaceutical chemistry. Its production process is fine and complex, and it is described in detail in the following ancient sayings.
The choice of starting materials is crucial. It is necessary to choose those with high purity and stable properties to build a solid foundation for subsequent reactions. The raw materials are put into the kettle and mixed in exquisite proportions, just like tuning and setting the tone. The slightest difference can lead to a thousand miles of results.
The control of reaction conditions, such as controlling a strong horse, must be precise and accurate. The temperature is high and low, just like the change of solar terms, or warm, or blazing, depending on the reaction stage. If it is too high, the reaction will be too intense, and if it is too low, it will stagnate. The pressure cannot be ignored, and it is as stable as Mount Tai to ensure a smooth reaction.
The addition of catalysts, such as water from a canal, can start the reaction trend. Its type and dosage have been repeatedly tried to obtain the best catalytic effect. With proper catalysis, the reaction rate will surge and the purity of the product will also be guaranteed.
During the reaction process, if you are walking on a boat in water, you need to monitor it at all times. With precision instruments, you can gain insight into the changes of the reaction and ensure that every step is under control. If there is any deviation, adjust it quickly to avoid major mistakes in brewing.
The product is initially formed and needs to be refined. After separation, impurities are removed and essence is retained. Then use the method of refining to sublimate the quality and finally obtain a pure and flawless product.
Packaging and storage should not be light. Choose the appropriate equipment to keep the product from moisture and oxidation, just like building a strong barrier for it to protect its long-term stability. Such a complicated production process, rigorous step by step, can only obtain this key compound.
What are the side effects of 1-Cyclopropyl-6-Fluoro-8-Methoxy-7- (3-Methylpiperazin-1-Yl) -4-Oxo-1, 4-Dihydroquinoline-3-Carboxylic Acid Methanesulfonate (1:1)?
1-Cyclopropyl-6-fluoro-8-methoxy-7- (3-methylpiperazine-1-yl) -4-oxo-1,4-dihydroquinoline-3-carboxylic acid methanesulfonate (1:1), although this drug has the ability to cure diseases, it also has various side effects, which cannot be ignored.
First, it often affects the gastrointestinal tract. Take it, or cause epigastric discomfort, such as nausea, vomiting, abdominal pain, and even diarrhea. This is because the drug enters the body, stimulates the mucosa of the stomach and intestines, and disrupts its function of transportation, transformation and conduction, so there are all kinds of symptoms.
Second, it also has an effect on the central nervous system. After taking the drug, some patients may feel dizzy, in a trance, or even insomnia. This is because the drug affects the peace of the brain and mind, causing the gods to lose their senses and be restless.
Third, it also has potential harm to the bones and muscles. Especially in children, pregnant women, etc., the drug should be used with caution. Because it may affect the growth and development of the bones, make the muscles and bones weak and weak to walk. Because the drug interferes with the normal metabolism of the bones and damages the growth and nourishment of the bones.
Fourth, it can still cause allergies. In mild cases, the skin is itchy and the rash points are faint; in severe cases, the breathing is short, even life-threatening. This is due to the different qi and blood endowments of the human body. Those who are allergic to this medicine will experience qi and blood rebellion and become allergic.
When a doctor uses this medicine, he should carefully examine the patient's body, weigh the pros and cons, and must not act like a monkey wave, so as not to cause harm to the patient.
1-Cyclopropyl-6-Fluoro-8-Methoxy-7- (3-Methylpiperazin-1-Yl) -4-Oxo-1, 4-Dihydroquinoline-3-Carboxylic Acid Methanesulfonate (1:1) market outlook?
1-Cyclopropyl-6-fluoro-8-methoxy-7- (3-methylpiperazine-1-yl) -4-oxo-1,4-dihydroquinoline-3-carboxylic acid methanesulfonate (1:1), which is a class of compounds in the field of pharmaceutical chemistry, is often used as a key active ingredient in the development of antibacterial drugs.
Under today's market structure, the demand for antibacterial drugs has always maintained a certain scale. With the development of society, the flow of people has intensified, and bacterial infections have occurred from time to time, which has made the antibacterial drug market stable. As far as such specific compounds are concerned, due to their unique chemical structure, they are endowed with potential antibacterial activity advantages.
In the past, pharmaceutical research and development mostly focused on common antibacterial ingredients, and insufficient attention was paid to compounds with novel structures. Nowadays, scientific research progress has prompted many pharmaceutical companies and scientific research institutions to focus on antibacterial compounds with unique structures, and this compound is also among them. Due to the increasingly serious problem of bacterial resistance, the efficacy of traditional antibacterial drugs has been frustrated, so the exploration of new antibacterial ingredients is particularly urgent.
Some cutting-edge scientific research results suggest that this compound may have a good inhibitory effect on specific drug-resistant strains. Although it may not be mass-produced and widely used in clinical practice at this stage, it has aroused the interest of many R & D teams. With the follow-up research, if the preparation process can be overcome and its pharmacological properties optimized, it is very likely to become a competitive new product in the antibacterial drug market in the future, opening up new avenues for the treatment of bacterial infections.