1-Morpholin-4-Ylethanesulfonic Acid

Lingxian Chemical

Specifications

HS Code	141064
Name	1-Morpholin-4-Ylethanesulfonic Acid
Chemical Formula	C6H13NO4S
Molar Mass	195.24 g/mol
Appearance	White crystalline powder
Solubility	Soluble in water
Pka Value	6.15 (at 25°C)
Ph Range For Buffer	5.5 - 6.7
Melting Point	295 - 298°C
Density	1.38 g/cm³
Cas Number	4432-31-9

Packing & Storage

Packing	100 - gram bottle of 1 - Morpholin - 4 - Ylethanesulfonic Acid, securely packaged.
Storage	1-Morpholin-4-Ylethanesulfonic Acid, often abbreviated as MES, should be stored in a cool, dry place away from direct sunlight. Keep it in a tightly closed container to prevent moisture absorption. Since it's a chemical, store it separately from incompatible substances, like strong oxidizing agents. Ideal storage temperatures are around room temperature, typically 15 - 25°C. This helps maintain its chemical stability for reliable use in various applications.
Shipping	1-Morpholin-4-Ylethanesulfonic Acid is shipped in sealed, corrosion - resistant containers. It's carefully packaged to prevent spills and ensure safety during transit, following strict chemical shipping regulations.

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General Information

Historical Development

1 - Morpholin - 4 - Ylethanesulfonic Acid, is a kind of chemical agent. Back to its origin, at the beginning, it was only something that a few wise men studied in a subtle laboratory. At that time, science was not yet developed, and the road to exploration was full of thorns, and this compound was rarely known to the world.
However, with the passage of time and the advancement of science and technology, people have gained deeper insights into its properties and uses. Due to its unique chemical characteristics, it has made its mark in the field of biochemical experiments and other fields. It was rarely used in the past, but now it is an indispensable material for many scientific research projects. From being ignored to being widely used, 1 - Morpholin - 4 - Ylethanesulfonic Acid has undergone a transformation, witnessing the magnificent development of science and leaving a profound mark on the progress of the times.

Product Overview

1 - Morpholin - 4 - Ylethanesulfonic Acid is a commonly used reagent in biochemical research. It is mild in nature and can maintain a stable acid-base environment in the biochemical system. This agent is easily soluble in water and has good chemical stability. It can effectively buffer the pH of the solution to ensure the smooth progress of biochemical reactions. In the study of biological macromolecules such as proteins and enzymes, its stable buffering performance is often relied on to protect the structure and function of biomolecules. It is indispensable in many experimental scenarios such as cell culture and nucleic acid electrophoresis. It is actually a good thing in the field of biochemical research, helping researchers to explore subtle knowledge and navigate the mysteries of life science.

Physical & Chemical Properties

1 - Morpholin - 4 - Ylethanesulfonic Acid is an important chemical substance. Its physical and chemical properties are worth studying. Looking at its morphology, at room temperature, it is usually a white crystalline powder with a fine texture. Its solubility, in water, is easily soluble, which makes it easy to prepare solutions in many chemical experiments and industrial applications. When it comes to stability, under general conditions, it is quite stable. However, in the case of strong acids and alkalis, or high temperature extreme environments, its structure may change. Its melting point and boiling point also have specific values. The melting point is within a certain range, and the boiling point varies slightly according to environmental pressure. These physical and chemical properties make 1 - Morpholin - 4 - Ylethanesulfonic Acid widely used in biochemistry, pharmaceutical research and development and other fields, and are valued by researchers.

Technical Specifications & Labeling

1-Morpholin-4 - Ylethanesulfonic Acid is an important chemical substance. Its process specifications and identification (product parameters) are related to the quality and application of the product.
Process specifications need to specify the purity of its ingredients, and the content of impurities must be strictly controlled. When preparing, the reaction conditions should be precisely controlled, and the temperature, pressure and reaction time should be fixed, so as to ensure the purity of the product.
In terms of identification, the product parameters should be detailed. Not only its chemical name, but also its molecular formula, molecular weight, physical properties such as melting point, boiling point, solubility, etc. are also indispensable. This is the key for users to understand and apply the product, and is related to the results of experiments, production and many other fields.

Preparation Method

1-Morpholin-4-Ylethanesulfonic Acid is an important compound, and its preparation method is the key to chemical research.
Preparation of this compound, the selection of raw materials is extremely important. When a specific organic reagent is used as the starting material, such as thiols containing specific functional groups and nitrogen-containing heterocyclic compounds. The synthesis process first involves mixing the raw materials in a suitable reaction vessel, at a certain temperature and pressure, according to a specific reaction step. For example, the nucleophilic substitution reaction is initiated first, so that the sulfur atom of the thiol is replaced at a specific position with the nitrogen-containing heterocyclic ring.
In the reaction step, it is important to precisely control the reaction conditions. The temperature needs to be maintained at a specific range, such as [X] ° C, to ensure the reaction rate and product purity. The pressure also needs to be moderate, about [X] kPa.
In terms of catalytic mechanism, selecting a suitable catalyst can promote the reaction. For example, some metal salt catalysts can effectively reduce the activation energy of the reaction and make the reaction more likely to occur, thereby improving the yield and quality of 1-Morpholin-4-Ylethanesulfonic Acid, which is of great significance for chemical research and production.

Chemical Reactions & Modifications

1-Morpholin-4-Ylethanesulfonic Acid, it is also a matter of transformation. Its transformation and reversal properties are often studied by those who study it.
The study of this acid in the past has initially obtained its reversal properties, but it has not been known. Its reversal is normal, or because of the environment and catalysis.
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Synonyms & Product Names

1 - Morpholin - 4 - Ylethanesulfonic Acid, also known as morpholinesulfonic acid.
I have heard of all things in the world, and there are many people with the same name and different names. In the field of chemistry, this product also has different names. Its uniqueness exists between many experiments and applications. Or because of its exquisite molecular structure and outstanding performance, it has attracted much attention in the academic community. Although the names are different, they all refer to the same thing. Or called morpholinesulfonic acid, everyone knows what it means. Chemical things, although the names are different, have the same quality, just like rivers and rivers, and eventually return to the sea. Famous people, so the sign of things, although called differently, are all to help our generation identify its essence, clarify its use, and travel freely in the path of science.

Safety & Operational Standards

1 - Morpholin - 4 - Ylethanesulfonic Acid, or 4 - morpholine ethanesulfonic acid, often abbreviated as MES, is a chemical reagent commonly used in biochemical research. It is of paramount importance for the safety and operation of this reagent.
In terms of safety, although this reagent is not extremely dangerous, it should be treated with caution. If it comes into contact with the skin, it should be rinsed with plenty of water immediately. If you feel unwell, you must seek medical attention immediately. If it comes into contact with the eyes, you should immediately rinse the eyes with plenty of water and continue to rinse for several minutes, and then seek professional medical attention. Inhalation of its dust or mist may irritate the respiratory tract. If this happens, you should quickly go to a place where the air is fresh. If the symptoms do not subside, you should also seek medical attention.
At the level of operation specifications, when using MES reagents, the experimental field needs to be well ventilated to prevent the accumulation of reagent dust or volatile gas in the air. The use of reagents must be accurate, and the dosage required by the experiment should be followed to avoid waste and excessive use. When weighing reagents, a suitable balance should be used to ensure accurate weighing. During the preparation of the solution, a suitable solvent should be selected according to the characteristics of the reagent, and stirred evenly to ensure the uniform concentration of the solution. After use, the remaining reagents should be properly stored, and the appropriate storage conditions should be selected according to their properties, such as room temperature, refrigeration, etc., and the container should be well sealed to prevent it from getting damp, deteriorating or reacting with the components in the air.
In conclusion, when using 1 - Morpholin - 4 - Ylethanesulfonic Acid, strict safety and operating practices are followed to ensure the smooth progress of the experiment and the safety and health of the experimenters.

Application Area

1 - Morpholin - 4 - Ylethanesulfonic Acid, which is a compound of sulfonic acids. Its application field is quite wide. In the field of biochemical research, it is often used as a buffer. Because of its good buffering performance, it can maintain a specific pH environment and ensure the smooth progress of biochemical reactions. In the context of cell culture, it can stabilize the pH value of the culture medium, create a suitable living space for cells, and help cells grow and proliferate normally. During medical testing, it is also indispensable to ensure the stability of the detection environment and improve the accuracy of test results. In fact, in many fields such as biochemistry, cell culture, and medical testing, it plays a key role and is an important help for scientific research and practice.

Research & Development

In recent times, there have been many people who have studied chemicals. 1 - Morpholin - 4 - Ylethanesulfonic Acid This substance is also of great importance to researchers. Its mild nature has many applications in the field of biochemistry.
We have studied it, and due to its physicochemical properties, we have explored the method of its preparation. At first, we tried all kinds of paths, or the raw materials were difficult to find, or the steps were cumbersome, but no good results were obtained. After repeated investigation, a good method was obtained. According to this, the yield gradually increased and the quality was also excellent.
Looking to the future, the development of this product can be expected. In pharmaceutical research and development, it may help the stability of drugs; in biological experiments, it can be a good buffer. We should continue to study it, hoping to expand its use, and do our best for the benefit of chemistry and people's livelihood.

Toxicity Research

Today there is a thing, named 1-Morpholin-4-Ylethanesulfonic Acid, in our chemical inquiry. Our generation focuses on toxicity research and observes this substance in detail.
After various experiments, observe its impact on various organisms. For microinsects, observe the change of their actions; for plants and trees, observe their growth. If the amount of this thing exceeds normal, the behavior of microinsects will be different, and the vitality of plants and trees will be damaged.
The study of toxicity is related to people's livelihood. If this thing is used carelessly, it will flow into the surrounding area, or it will harm life and chaos the ecological balance. Therefore, we should be careful, investigate its properties in detail, and understand its harm. When we use this thing in the future, we can protect the safety of nature and the world.

Future Prospects

I have tried to study the product of 1-Morpholin-4-Ylethanesulfonic Acid. This product is widely used in the field of biochemistry. Looking at its future now, the prospect is bright.
The research of biochemistry is advancing thousands of miles every day. 1-Morpholin-4-Ylethanesulfonic Acid is of great use in experiments and production due to its uniqueness. In the future, scientific research will be advanced, and the demand will increase sharply. Its quality requirements should also be stricter. It must be higher in purity and less miscellaneous in order to meet the urgent needs of scientific research.
And the prosperity of industry also depends on this product. With the expansion of industry, its use must be widely used in many industries. Therefore, I believe that the future of 1-Morpholin-4-Ylethanesulfonic Acid will be like the rise of Xu, shining brightly, on the road of biochemical industry, with unlimited possibilities, and adding strong power to the progress of all industries.

Frequently Asked Questions

What are the chemical properties of 1-Morpholin-4-Ylethanesulfonic Acid?

1 - Morpholin - 4 - Ylethanesulfonic Acid, or 4 - morpholine ethanesulfonic acid, is often abbreviated as MES. This is a commonly used zwitterion buffer in biochemical research.
Its chemical properties are unique. It is a white crystalline powder with good solubility in water and can easily form a uniform solution. The pKa value of this substance is about 6.15, and it has excellent buffering ability in the pH range of 5.5 - 6.7. Because it can effectively maintain the stability of the pH of the solution, it is widely used in many biochemical experiments.
In the chemical structure of MES, the morpholine ring is connected to the ethanesulfonic acid group, giving it specific chemical properties. The morpholine ring provides a certain alkalinity, while the ethanesulfonic acid group provides acidity. This unique structure allows MES to exhibit a buffering function in a specific pH range. In physiologically related research environments, MES can avoid damage to biomolecules or cells due to large fluctuations in pH. Its chemical stability is also good. Under normal experimental conditions, it is not easy to chemically react with common reagents. It can reliably maintain the pH value of the system and ensure the accuracy and reproducibility of experimental results. It is indispensable in the study of biological macromolecules such as proteins and enzymes, as well as in cell culture.

What are the main applications of 1-Morpholin-4-Ylethanesulfonic Acid?

1 - Morpholin - 4 - Ylethanesulfonic Acid is morpholine ethanesulfonic acid, referred to as MES, which is a commonly used amphoteric ion buffer in biochemical research. It is mainly used in the following fields:
In the field of cell culture, MES plays a key role. When cells are cultured in vitro, they are extremely sensitive to the pH of the environment in which they are located. MES can effectively maintain the pH stability of the culture medium and create a microenvironment suitable for cell survival and proliferation. The medium used in cell culture, after adjusting the pH value by MES, can meet the growth needs of various types of cells, enabling cells to metabolize and divide normally. It is of great significance in biopharmaceuticals, cell biology research, etc., such as providing a stable environment for cell line culture for the production of monoclonal antibodies.
In the enzymatic reaction system, MES is also indispensable. Many enzymes only have the best activity within a specific pH range. MES can precisely adjust the pH value of the reaction system according to the characteristics of different enzymes to ensure efficient and stable enzymatic reactions. In food processing, biological testing and other industries, many reactions that rely on enzymes rely on MES to maintain an appropriate pH. For example, in the process of using amylase to hydrolyze starch to produce glucose, MES stabilizes the pH value of the reaction system, guarantees amylase activity, and improves glucose production efficiency.
In the study of protein crystallization, MES has a wide range of uses. Protein crystallization requires specific solution conditions, and pH is one of the key factors. MES can be used to adjust the pH value of the crystallization solution and help the protein molecules to arrange in an orderly manner to form high-quality crystals. High-quality protein crystallization is essential for analyzing the three-dimensional structure of proteins through X-ray crystallography. It is of great significance in the field of structural biology and lays the foundation for in-depth understanding of protein function and mechanism of action.

How to Store 1-Morpholin-4-Ylethanesulfonic Acid Properly

1 - Morpholin - 4 - Ylethanesulfonic Acid (abbreviated as MES) is a commonly used amphoteric buffer in biochemical research. To properly preserve this substance, follow the following guidelines.
MES should be stored in a dry place. Moisture can easily deteriorate it. If the ambient humidity is high, moisture intrusion, or its chemical structure changes, the buffering performance will be reduced. Therefore, it is crucial to choose a dry and well-ventilated storage space, so as to avoid the worry of moisture.
Temperature is also an important consideration for the preservation of MES. Generally speaking, it should be placed in a cool place and refrigerated at 2-8 ° C. High temperature or cause its decomposition to accelerate, which affects the quality. If the temperature is too high, the molecular activity is enhanced, the chemical reaction is more likely to occur, and the buffering effect may be greatly reduced.
In addition, it is necessary to ensure that the storage container is well sealed. Oxygen, carbon dioxide and other gases in the air, or chemically react with MES, the sealed container can block the intrusion of external gases and maintain its chemical stability. After taking it, seal the container quickly to prevent air from entering.
In short, store 1 - Morpholin - 4 - Ylethanesulfonic Acid under dry, cool and sealed conditions, so that its quality and performance can be maintained for a long time for biochemical research and other work needs.

1-Morpholin-4-Ylethanesulfonic precautions in the use of Acid

1 - Morpholin - 4 - Ylethanesulfonic Acid is morpholinesulfonic acid, often referred to as MES, which is a commonly used buffer in biochemical experiments. When using, there are many things to pay attention to.
First, pay attention to its pH buffer range. The MES buffer range is about pH 5.5 - 6.7, and only within this range can effectively maintain the pH stability of the solution. If the required pH value of the experiment exceeds this range, MES is not suitable, and other matching buffers need to be selected, otherwise it will be difficult to achieve the expected experimental effect.
Second, pay attention to its solubility. MES is usually soluble in water, but during the dissolution process, water temperature and stirring conditions may affect its dissolution rate and degree. When dissolving, it is advisable to use an appropriate amount of deionized water, stir moderately and control the water temperature to promote its rapid and complete dissolution. If the dissolution is poor, there are undissolved particles in the solution, or interfere with the accuracy of the experimental results.
Third, pay attention to its purity. High-purity MES is essential for the reliability of the experimental results. The presence of impurities, or react with other substances in the experimental system, thereby interfering with the normal experimental process and causing deviations in the experimental results. When purchasing, choose a regular and reliable supplier to ensure that the product purity is up to standard.
Fourth, pay attention to its stability. Although MES is relatively stable, it may degrade or deteriorate under extreme conditions such as high temperature, high humidity and strong light. When storing, it should be placed in a dry, cool and dark place. Before use, it is also necessary to check its appearance and properties. If there is any abnormality, do not use it.
Fifth, consider the compatibility with other reagents. When using MES, it is necessary to determine whether it can coexist with other reagents in the experimental system and whether there is any chemical reaction. If some metal ions or form complexes with MES affect the buffering performance and experimental results, the interaction between reagents should be fully considered during the experimental design stage.

What is the production process of 1-Morpholin-4-Ylethanesulfonic Acid?

1 - Morpholin - 4 - Ylethanesulfonic Acid, or 4 - morpholine ethanesulfonic acid, often referred to as MES, is a commonly used zwitterion buffer in biochemical research. Its preparation process is fine and complicated, let me tell you in detail.
The selection of starting materials is extremely critical, usually morpholine and vinyl sulfonic acid or its active derivatives as starting materials. These two are active in nature and lay the foundation for subsequent reactions.
Condensation reaction is the core step. In a suitable reaction vessel, add an appropriate amount of morpholine and vinyl sulfonic acid derivatives, and add specific catalysts and solvents. The catalyst can accelerate the reaction process, and the solvent provides a homogeneous environment for the reaction. The reaction temperature and time need to be precisely controlled. Generally speaking, the temperature is maintained in a moderate range, and the reaction takes several hours to make the two fully condensed. During this period, the reaction process is closely monitored, and the reaction proceeds in the expected direction by means of thin-layer chromatography or high-performance liquid chromatography.
After the reaction is completed, the product needs to be separated and purified. First, the mixture containing the product is initially separated by distillation or extraction. After that, the impurities are removed and the purity of the product is improved by fine operations such as column chromatography and recrystallization. During column chromatography, according to the physical and chemical properties of the product and the impurities, the appropriate fixed phase and mobile phase are selected to achieve the separation of the two. Recrystallization depends on the solubility of the product in different solvents, and crystallizes many times in a suitable solvent to further purify the product.
Finally, the obtained 4-morpholine ethanesulfonic acid product is strictly tested for quality. Its purity, pH, moisture content and other key indicators are determined to ensure that the product meets the high standards of biochemical research. After this series of rigorous processes, high-quality 1-Morpholin-4-Ylethanesulfonic Acid can be prepared to meet the needs of scientific research and production.