What is the chemical structure of (1R )-( - )- 10 - Camphors ulf on ic Acid
(1R) - (+) -10-camphor sulfonic acid, its chemical structure is as described above. (1R) - (+) -10-camphor sulfonic acid is the product of camphor sulfonation. Its structural core is the skeleton of camphor, that is, the structure of camphene. The camphene structure has a rigid bridge ring system, which is formed by fusing two six-membered rings. The bridge ring system contains one bridgehead quaternary carbon atom and two bridging methylates.
is connected to a sulfonic acid group (-SO 🥰 H) at a specific position in the camphene skeleton, that is, at position 10. This sulfonic acid group gives the compound acidic properties and plays a key role in many chemical reactions and applications. And because the compound has chirality, it is marked with (1R), indicating that the absolute configuration of its chiral center is R-type. This chiral property has important uses in asymmetric synthesis, chiral resolution and other fields. In summary, the chemical structure of (1R) - (+) -10-camphor sulfonic acid is a unique structure of camphene skeleton with a specific chiral configuration and a sulfonic acid group, which endows it with diverse chemical properties and application values.
(1R )-( - )- 10 - What are the main uses of Camphors ulf on ic Acid
(1R) - (+) -10-camphor sulfonic acid, which has a wide range of uses. In the field of medicine, its role is particularly significant. Often used as a chiral resolution agent, it can split the racemate into a single enantiomer. In many drug synthesis processes, chiral compounds of specific configurations need to be obtained. (1R) - (+) -10-camphor sulfonic acid can accurately identify and separate enantiomers by virtue of its chiral characteristics, which can help synthesize high-purity chiral drugs, improve drug efficacy and reduce adverse reactions.
It also plays an important role in organic synthesis. It can be used as an efficient acid catalyst to catalyze many organic reactions. For example, esterification reaction can speed up the reaction process and improve the reaction yield. Due to its chiral environment, in some asymmetric synthesis reactions, it can also induce the reaction to proceed in a specific chiral direction, and synthesize compounds with optical activity, which is of great significance for the creation of new organic materials and the total synthesis of natural products.
In the field of materials science, (1R) - (+) -10-camphor sulfonic acid has also emerged. It can be used to prepare chiral conductive polymers, which endow materials with special electrical and optical properties and show potential application value in the field of optoelectronics. In addition, in the preparation of some chiral liquid crystal materials, it can adjust the arrangement of liquid crystal molecules and improve the properties of liquid crystal materials, so that the materials play a unique role in display technology and so on.
What are the physical properties of (1R )-( - )- 10 - Camphors ulf on ic Acid
(1R) -(-) -10-camphor sulfonic acid is an organic compound. It has many physical properties, which are described in detail by you.
Looking at its appearance, it is often in the shape of a white crystalline powder, delicate and uniform, and has a good luster. This is its external significant characteristic, which can be intuitively observed by humans.
When it comes to solubility, its solubility in water is quite good. Water is the source of life and an excellent medium for many chemical reactions. (1R) -(-) -10-camphor sulfonic acid is soluble in water, so it can participate in various reactions in aqueous systems. This characteristic is widely used in chemical, pharmaceutical and other fields. And in alcoholic solvents, it also has a certain solubility, such as ethanol, which makes it more likely to be used in organic synthesis.
Melting point is also an important physical property. Its melting point is in a specific range, which is helpful for the identification and purity judgment of the substance. When the substance is heated to a specific temperature, it gradually changes from a solid state to a liquid state, and this temperature is the melting point. Accurate determination of the melting point can help determine the purity of the substance. If the purity is high, the melting point range is narrow and close to the theoretical value; if it contains impurities, the melting point may be deviated and the range may be widened.
In addition, the substance has certain hygroscopicity. When water vapor exists in the air, it can absorb water vapor, causing its own state to change. Attention should be paid to this during storage and use, and it should be stored in a dry environment to avoid affecting its quality and performance due to moisture absorption.
(1R) -(-) -10-camphor sulfonic acid The physical properties are of critical significance in industrial production, scientific research and practical applications, and are valued by practitioners in related fields.
What are the synthesis methods of (1R )-( - )- 10 - Camphors ulf on ic Acid
The synthesis method of (1R) - (+) -10-camphor sulfonic acid has been known since ancient times. In the past, Fang family followed a specific path and adopted all kinds of wonderful methods to make this product.
First, it can be started by natural camphor. Natural camphor is derived from the essence of camphor plants. It is first sulfonated and interacted with sulfonating reagents such as sulfuric acid. Under appropriate temperature and pressure, the active group of the sulfonating agent gradually enters the molecular structure of camphor. After a series of delicate reactions, the structure of camphor is changed, and finally (1R) - (+) -10-camphor sulfonic acid is obtained. This way depends on natural materials, but the preparation process needs to be carefully regulated to ensure the pure configuration of the product and excellent activity.
Second, it is also based on the chemical synthesis path. Starting from the basic organic compounds, through multi-step ingenious reaction design. First build a basic skeleton similar to camphor with suitable raw materials, and then introduce sulfonic acid groups. This process requires careful consideration of reaction conditions, such as temperature and catalyst selection. The catalyst can accelerate the reaction process, guide the desired reaction direction, and make the synthesis path smoother. The control of temperature cannot be ignored. Too high or too low may cause reaction deviation and the product is impure.
And when synthesizing, the technology of separation and purification is also key. The product is often mixed in the reaction system, with unreacted raw materials, by-products, etc. It is necessary to use recrystallization, chromatographic separation and other methods to precipitate (1R) - (+) -10-camphor sulfonic acid from the complex mixture to obtain a pure product, which is suitable for practical use. This synthesis method is actually a delicate display of organic synthesis skills. It requires the synthesizer to have both profound knowledge and skilled operation to achieve this good product.
What is the price range of (1R )-( - )- 10 - Camphors ulf on ic Acid in the market
The price range of (1R) -(-) -10-camphor sulfonic acid in the market is difficult to determine. This can be determined by many factors, such as the situation of supply and demand, the difference in quality, the difference in origin and the change in market conditions.
If it is said that in the city of the past, the price may change according to the times. When the supply and demand are stable and the quality is ordinary, the price may be in a certain range. However, if the supply is less than the demand, if the demand increases sharply in a certain season, and the production does not rise accordingly, the price may rise. And if the quality is high and specially refined, the price should also be higher than that of ordinary ones.
The difference in origin also has an impact. Shipped from a distance, with the addition of freight, taxes, etc., the price may be higher than that of nearby products. And the market conditions are changing rapidly, the economic situation, policies and regulations, etc., can cause fluctuations in prices.
To know the exact price range, check the chemical raw material trading platform, inquire from suppliers or refer to recent market transaction records to get a more accurate price.