(1R,2S)-1-Amino-N-(Cyclopropylsulfonyl)-2-Ethenylcyclopropanecarboxamide 4-Methylbenzenesulfonate (1:1)

This is the chemical structure of (1R, 2S) -1 -amino-N - (cyclopropylsulfonyl) -2 -vinylcyclopropane formamide 4 -methylbenzene sulfonate (1:1). To clarify its structure, first analyze the names of each part. " ( 1R, 2S) "The configuration of chiral carbon," 1-amino "epicyclopropane at 1-position hydrazine," N- (cyclopropylsulfonyl) "epicynitrogen atom-linked cyclopropylsulfonyl group," 2-vinyl "shows cyclopropane at 2-position-linked vinyl," cyclopropane formamide "is the main structure, which is a cyclopropane-derived formamide." 4-methylbenzene sulfonate (1:1) "table and 4-methylbenzene sulfonate are salts in a 1:1 ratio. Its chemical structure is roughly, with cyclopropane formamide as the core, 1-position amino group, 2-position vinyl group, nitrogen atom-linked cyclopropyl sulfonyl group, and salt with 4-methylbenzenesulfonic acid. In this structure, cyclopropane has unique tension, and amino group, vinyl group, and cyclopropyl sulfonyl group have their own characteristics, which may affect its physicochemical properties and activities after being salted.

(1R, 2S) -1 -amino-N - (cyclopropylsulfonyl) -2 -vinylcyclopropane formamide 4 -methylbenzenesulfonate (1:1) is an organic compound. Its physical properties are quite characteristic.
Looking at its morphology, it is often in the shape of white to quasi-white crystalline powder. This morphology is easy to store and use, and reflects the order of its molecular arrangement.
When it comes to the melting point, it is about a specific temperature range. This temperature is the critical value for the transformation of a substance from a solid state to a liquid state, reflecting the strength of intermolecular forces. The determination of the melting point is of great significance for identification and purity judgment.
In terms of solubility, it has a certain solubility in common organic solvents such as methanol and ethanol. This property is crucial in chemical synthesis and preparation, and is related to the reaction process and drug dosage form design.
In addition, its stability is also an important physical property. In a normal temperature and pressure, dark and dry environment, it can maintain a relatively stable chemical structure. In case of high temperature, high humidity or strong light, the structure may change, resulting in changes in its properties.
The physical properties of this compound play a significant role in chemical research, drug development and other fields, laying the foundation for subsequent reaction exploration and product development.

To prepare (1R, 2S) -1 -amino-N - (cyclopropylsulfonyl) -2 -vinylcyclopropane formamide 4 -methylbenzenesulfonate (1:1), the method is as follows:
Take the appropriate starting material first, and use the cyclopropane derivative as the base. This derivative needs to have a modifiable group for subsequent introduction of amino, cyclopropylsulfonyl and vinyl functional groups.
The first step is to perform a substitution reaction on the cyclopropane derivative. Select a suitable halogenated reagent to introduce a halogen atom at a specific position on cyclopropane. This halogen atom is a key check point for subsequent reactions and can promote the nucleophilic substitution reaction. After careful control of the reaction temperature, time and the proportion of reactants, the halogenated reaction can achieve high yield and selectivity.
Next step, introduce an amino group. Select a suitable amination reagent, common derivatives such as ammonia, under basic conditions and with the help of a phase transfer catalyst, nucleophilic substitution occurs with the halogenated cyclopropane derivative, so that the halogen atom is replaced by an amino group to form an amino-containing cyclopropane intermediate. This process needs to pay attention to the mildness of the reaction conditions to avoid side reactions caused by excessive influence of the amino group.
Furthermore, add a cyclopropylsulfonyl group. Cyclopropyl sulfonyl chloride is used as a raw material, and in the presence of an organic base, it reacts with an intermediate containing an amino group. The organic base can neutralize the hydrogen chloride generated by the reaction and promote the forward reaction. The cyclopropyl sulfonyl group is successfully attached to the amino nitrogen atom to obtain an important intermediate.
Then, the vinyl group is constructed. Through a suitable alkenylation reaction, such as the Wittig reaction or the Heck reaction. If the Wittig reaction is used, a suitable phosphorus ylide reagent needs to be prepared, which reacts with the intermediate containing a specific functional group under mild conditions to generate a product with a vinyl group. In this step, the reaction conditions are precisely controlled to ensure the correct configuration of the vinyl and the high efficiency of the reaction.
Finally, 4-methylbenzenesulfonate is formed. The above product is taken and reacted with 4-methylbenzenesulfonyl chloride under alkali catalysis and carried out in a suitable solvent. The alkali can activate specific hydroxyl or amino groups in the product, so that it undergoes nucleophilic substitution with 4-methylbenzenesulfonyl chloride to form the target product (1R, 2S) - 1-amino-N - (cyclopropylsulfonyl) - 2-vinylcyclopropane formamide 4-methylbenzenesulfonate (1:1). After the reaction, the high-purity product was obtained by extraction, column chromatography and other separation and purification methods.

(1R, 2S) -1 -Amino-N - (cyclopropylsulfonyl) -2 -vinyl cyclopropane formamide 4 -methylbenzenesulfonate (1:1) This substance has a rather specific use. It is often a key material in the process of pharmaceutical creation. When developing new antibacterial agents, it may be able to use its unique molecular structure to precisely fit with specific targets in pathogens and prevent their reproduction to achieve antibacterial effects.
In the field of organic synthesis, it is like a smart "masonry". With its diverse active groups, it paves the way for the construction of complex and delicate organic molecular structures. With carefully designed reaction paths, it can be integrated into macromolecular systems to shape novel compounds and contribute to the development of organic chemistry.
In the field of materials science, or because of its special chemical properties, it can give materials unique properties. Or it can improve the stability of materials, making them durable in complex environments; or it can enhance the affinity of materials, optimize their interaction with other substances, and emerge in the research and development of high-end materials, providing new ideas and opportunities for material innovation.

(1R, 2S) - 1 - amino - N - (cyclopropyl sulfonyl) - 2 - vinyl cyclopropane formamide 4 - methylbenzene sulfonate (1:1) is related to personal safety, the following things should be noted.
This is a chemical compound with specific chemical structures and properties. Many safety points must not be ignored during its production and preparation. Raw materials and reagents have dangerous properties, such as flammable, explosive, toxic or corrosive. Raw materials such as cyclopropyl sulfonyl chloride, contact with the skin, inhalation or ingestion, can seriously damage health. The operation must be in a well-ventilated environment, equipped with protective equipment, such as gas masks, protective gloves and goggles, etc., and strictly follow the standard procedures.
The reaction process also requires caution. Improper control of temperature, pressure, reaction time, or uneven stirring may cause the reaction to go out of control, causing explosion or toxic gas leakage. It is necessary to accurately monitor and regulate the reaction conditions, and equip emergency treatment devices.
Product storage should also not be ignored. It should be placed in a cool, dry and well-ventilated place, away from fire sources, heat sources and oxidants. Because of its chemical activity, improper storage is prone to deterioration or dangerous reactions.
During use, operators must undergo professional training and be familiar with its nature and safety precautions. Avoid contact with incompatible substances to prevent dangerous reactions. In case of inadvertent contact, emergency treatment measures should be taken immediately. If skin contact is immediately rinsed with plenty of water, and serious cases should be taken to the hospital.
When transporting, follow the transportation specifications of hazardous chemicals to ensure that the packaging is intact and the identification is clear to prevent leakage and accidents. The safety of this compound is interlinked, and any mistake in any link may lead to a big disaster, and it must not be slack.