What are the chemical properties of [ (1R) -7,7-dimethyl-2-oxobicyclo [2.2.1] heptyl-1-yl] methanesulfonic acid
(1R) -7,7-dimethyl-2-oxobicyclic [2.2.1] heptyl-1-ylacetic acid, this compound has unique chemical properties. Its chemical properties are derived from the synergistic effect of the bicyclic [2.2.1] heptane skeleton, the dimethyl group, and the carbonyl and carboxyl groups in the structure.
From the perspective of spatial structure, the bicyclic [2.2.1] heptane skeleton endows it with a rigid structure, restricts the intramolecular rotation, and affects the intermolecular interaction. The dimethyl group gives the molecule a certain local spatial resistance, which changes the physical and chemical properties of the compound, such as affecting the physical parameters such as boiling point and melting point, and also has an effect on the chemical reaction activity and selectivity. The carbon-oxygen double bond in carbonyl (C = O) has strong polarity, and the carbon is partially positively charged. It is easily attacked by nucleophiles and occurs nucleophilic addition reactions. For example, acetals are formed with alcohols under acid catalysis, and new carbon-carbon bonds are formed by reacting with Grignard reagents. Carboxyl (-COOH) is acidic and can dissociate hydrogen ions in water and react with bases to form salts. Esterification reactions can also occur, and esters are formed with alcohols under the catalysis of concentrated sulfuric acid.
Due to these chemical properties, this compound is used in the field of organic synthesis to construct complex cyclic structures. As a key intermediate to synthesize biologically active natural products or drug molecules, it has great potential for application in medical chemistry, materials science and other fields.
[ (1R) -7,7-dimethyl-2-oxobicyclo [2.2.1] heptyl-1-yl] methanesulfonic acid in which applications
(1R) -7,7-dimethyl-2-oxobicyclic [2.2.1] heptyl-1-ylacetic acid, which is widely used.
In the field of medicine, it can be used as a key intermediate to create a variety of drugs. For example, in the synthesis process of some anti-inflammatory drugs, its structural properties can impart specific activity and targeting to drugs, help improve drug efficacy, and reduce adverse reactions at the same time. It is like the cornerstone of Seiko craftsmanship and adds to the building of medicine.
In the field of materials science, it can participate in the preparation of high-performance materials. Due to its unique molecular structure, it can improve some properties of materials, such as enhancing the stability and toughness of materials. It is like a magical reagent, injecting extraordinary characteristics into materials, so that materials can show excellent performance in different environments.
In the field of organic synthesis, it is like a master key and an important starting material for the construction of complex organic compounds. With its special structure, chemists can use various reactions to derive a rich variety of organic molecules, greatly expanding the boundaries of organic synthesis and opening up a broader world for the development of organic chemistry.
What is the synthesis method of [ (1R) -7,7-dimethyl-2-oxobicyclic [2.2.1] heptyl-1-yl] methanesulfonic acid
To prepare\ ([ (1R) -7,7-dimethyl-2-oxobicyclic [2.2.1] heptyl-1-yl] acetic acid, it can be done according to the following ancient method.
First take a suitable starting material, based on a dicyclic [2.2.1] heptane derivative. This derivative undergoes the transformation of functional groups under specific reaction conditions.
In the first step, it is often necessary to introduce a suitable substituent, and a nucleophilic substitution reaction can be used. Choose a suitable nucleophilic reagent, react with the dicyclic [2.2.1] heptane derivative in a suitable solvent and temperature, and introduce a group that can be subsequently converted at a specific position.
Next step, the introduced group is oxidized. With a suitable oxidizing agent, such as some high-valent metal salts, the group is oxidized to a carbonyl group in a mild reaction environment to construct a 2-oxo structure.
Furthermore, dimethyl is introduced. A dimethyl-containing reagent can be selected. A reaction involving an organometallic reagent, such as a Grignard reagent reaction or a lithium reagent reaction, is connected to dimethyl at a suitable reaction check point to obtain a 7,7-dimethyl structure.
Finally, an acetic acid group is introduced through a carboxylation reaction. Carbon dioxide is used as the carboxyl source to react with the compounds with the above structures under a specific catalytic system to achieve the synthesis of [ (1R) -7,7-dimethyl-2-oxobicyclic [2.2.1] heptyl-1-yl] acetic acid. The reaction process requires fine control of reaction conditions, such as temperature, pH, reaction time, etc., to ensure the smooth progress of the reaction and the purity and yield of the product.
What is the market price of [ (1R) -7,7-dimethyl-2-oxobicyclo [2.2.1] heptyl-1-yl] methanesulfonic acid
I look at what you said about " (1R) -7,7-dimethyl-2-oxobicyclic [2.2.1] heptyl-1-ylacetic acid", which is a chemical substance. As for its market price, it is difficult to determine. The fluctuation of its price is related to various factors.
First, the difficulty of preparation is also. If the preparation process is complicated, many steps are required, and the yield of each step is not ideal, or the required raw materials are rare and difficult to find, and the price is high, the cost of this substance will be high, and the market price will also rise.
Second, the supply and demand situation of the market is important. If there is a strong demand for this product in the fields of medicine, chemical industry, etc., but there are few suppliers, the supply is in short supply, the price will rise; on the contrary, if there is little demand and excess supply, the price will fall.
Furthermore, the scale of production also has an impact. In large-scale production, due to the scale effect, the unit cost may be reduced, and the price may be more competitive; if it is only a small-scale production, the cost will not be reduced, and the price will be difficult to reach the people.
In addition, the situation of industry competition, changes in policies and regulations, etc., will affect its price. Therefore, in order to know the exact market price of this product, it is necessary to carefully investigate the market conditions of chemical raw materials, or consult professional chemical product suppliers and distributors to obtain a more accurate figure.
What are the storage conditions for [ (1R) -7,7-dimethyl-2-oxobicyclic [2.2.1] heptyl-1-yl] methanesulfonic acid?
(1R) -7,7-dimethyl-2-oxobicyclic [2.2.1] heptyl-1-ylacetic acid. The storage conditions for this substance are as follows:
This compound usually needs to be stored in a cool, dry and well-ventilated place. Due to its chemical properties or sensitivity to temperature and humidity, high temperature and humid environment may cause its deterioration or chemical reaction. The temperature should be controlled in a cool range of 2-8 ° C, which can effectively maintain its chemical stability and reduce the risk of molecular structure changes.
The storage place must be kept dry and the humidity should be maintained at a low level to prevent deliquescence or hydrolysis due to moisture absorption, which will adversely affect its quality and purity. In addition, it should be placed in a well-ventilated place to avoid potential safety hazards due to local accumulation of volatile gases.
At the same time, this compound may have certain chemical activity and danger. When storing, it should be kept away from fire sources, heat sources, and strong oxidants, reducing agents and other substances that may react violently with it to prevent dangerous accidents such as fire and explosion. The storage area should also be clearly marked to remind operators to pay attention to its characteristics and safety operation points.
In the process of taking and storing this compound, relevant personnel must strictly follow the safety regulations of laboratories or industrial sites, and take personal protective measures to ensure personal safety and environmental safety.