[1R- (Endo, Anti) ] What is the chemical structure of -3-Bromo-2-Oxobornane-8-Sulphonic Acid?
%5B1R-%28Endo%2CAnti%29%5D-3-Bromo-2-oxybornane-8-sulfonic acid, this is an organic compound. According to the naming rules of organic chemistry, the approximate outline of its structure can be known.
"%5B1R-%28Endo%2CAnti%29%5D" part reveals its stereochemical configuration. "1R" indicates that the configuration of a specific chiral center is R-type. "Endo" and "Anti" describe the spatial relative positional relationship of intramolecular groups, which is a key clue to understand its three-dimensional structure.
"3-Bromo" is shown at position 3 of the parent structure of the compound, which is connected with a bromine atom. Bromine atoms have unique chemical properties. Due to their electronegativity, they can have a significant impact on molecular reactivity and physical properties.
"2-oxo" Table 2 has a monocarbonyl (C = O) at position 2. The carbonyl group is a strong electron-absorbing group, which not only affects molecular polarity, but also acts as an active check point in many chemical reactions, and can undergo reactions such as nucleophilic addition.
"Bornane" determines its parent carbon skeleton structure. Bornane has a bridge-ring structure, which is connected by multiple carbon atoms in a specific way to form a unique ring system, endowing the molecule with rigidity and stability.
"8-sulfonic acid" indicates that there is a sulfonic acid group (-SO-H) at position 8. The sulfonic acid group is strongly acidic, which can make the compound soluble in water or polar solvents, and has special properties and applications in catalysis, ion exchange and other fields.
In summary, the chemical structure of %5B1R-%28Endo%2CAnti%29%5D-3-bromo-2-oxybornane-8-sulfonic acid fuses a variety of functional groups and specific three-dimensional configurations, and the interaction of each part determines its unique chemical and physical properties.
[1R- (Endo, Anti) ] What are the main uses of -3-Bromo-2-Oxobornane-8-Sulphonic Acid?
[1R- (internal type, trans) ] -3-bromo-2-oxybornane-8-sulfonic acid, which has a wide range of uses.
In the field of medicine, it can be used as a key intermediate to help synthesize many specific drugs. In the field of organic synthesis chemistry, it can be used to construct complex organic molecular structures due to its unique structure and reactivity. Because of its chiral characteristics, it is of great significance in asymmetric synthesis. It can induce reactions to generate products of a specific configuration, improve the optical purity and stereoselectivity of the products, which is of great significance for the preparation of biologically active compounds and the total synthesis of natural products.
can be used in the field of materials science, or can be used to prepare chiral functional materials, which are useful in nonlinear optics, chiral recognition and separation. For example, in the preparation of optical materials, special optical properties can be given to the material, such as circularly polarized luminescence properties, and then applied to frontier fields such as optical display and optical information storage. In the preparation of chiral recognition and separation materials, it can accurately identify and separate enantiomers, and has important applications in drug purification, environmental monitoring, food analysis and other fields.
With its unique chemical structure and properties, this compound plays an important role in many scientific research and industrial production fields, acting as a key to open the door to exploration and application in many frontier fields.
[1R- (Endo, Anti) ] What is the synthesis method of -3-Bromo-2-Oxobornane-8-Sulphonic Acid?
To prepare [1R- (internal type, trans) ] - 3-bromo-2-oxybornane-8-sulfonic acid, the synthesis method needs to be based on the principle of fine organic synthesis and step by step.
First, choose bornane as the initial raw material. Bornane is easy to obtain and inexpensive, and its structure is similar to the skeleton of the target product, which can lay the foundation for subsequent reactions. The bornane is oxidized to carbonyl group by oxidizing the hydroxyl group of the bornane to carbonyl group at a suitable temperature, reaction time and solvent environment, and 2-oxybornane is obtained. The key to this step is to precisely control the degree of oxidation to prevent the product from being impure due to excessive oxidation.
Second, the bromine atom is introduced at the 3-position of 2-oxybornane. A brominating agent such as bromine or N-bromosuccinimide (NBS) can be selected. If bromine is used, the bromine atom needs to be connected to the 3-position through a free radical substitution reaction at low temperature and in the presence of light or an initiator. If NBS is used, because of its mild reaction and good controllability, it is often used in organic solvents with benzoyl peroxide as the initiator to achieve the synthesis of 3-bromo-2-oxybornane. This step requires attention to the reaction conditions to prevent side reactions, such as the formation of polybrominates.
Furthermore, the sulfonic acid group is introduced at the 8-position. Concentrated sulfuric acid or fuming sulfuric acid is often used as a sulfonating agent, and under heating conditions, 3-bromo-2-oxybornane is reacted with the sulfonating agent. This step requires close attention to the reaction temperature and time. Because the sulfonation reaction is easy to be excessive, the introduction of too many sulfonic acid groups or other side reactions will affect the purity and yield of the target product.
Finally, after separation and purification, such as column chromatography, recrystallization, etc., to remove unreacted raw materials, by-products and impurities, pure [1R- (internal type, trans) ] -3-bromo-2-oxybornane-8-sulfonic acid is obtained. Throughout the synthesis process, the reaction conditions of each step need to be carefully controlled, and the products of each step need to be strictly tested to ensure the quality and yield of the final product.
[1R- (Endo, Anti) ] What are the physicochemical properties of -3-Bromo-2-Oxobornane-8-Sulphonic Acid?
[1R- (internal type, trans) ] -3-bromo-2-oxybornane-8-sulfonic acid has unique physical and chemical properties, which is quite attractive to explore.
In terms of appearance, it is often in the state of white to off-white crystalline powder, which is easy to observe and operate, and is easy to distinguish and use in many experimental scenarios. Its melting point is in a specific range, about [specific melting point value]. This melting point is of great significance to the determination of its purity and is one of the key indicators to measure the quality of this product.
In terms of solubility, it shows a certain solubility in common organic solvents such as ethanol and acetone, which can be understood according to the principle of similar compatibility. In water, it also has a certain solubility, which makes it able to participate in related reactions or processes in different systems, and is widely used in the chemical and pharmaceutical fields.
In terms of stability, under normal temperature and pressure, if there are no special interference factors, the properties of this compound are relatively stable. In case of high temperature, strong oxidizing agent or reducing agent, the structure is easily affected, and the chemical properties may change, so special attention should be paid to environmental factors when storing and using.
Its acidity is derived from sulfonic acid groups, and it has the general properties of acidic substances. It can neutralize and react with bases to form corresponding salts. And because of the special bridge ring and bromine, carbonyl and other functional groups in the structure, it has unique chemical reactivity and can participate in many organic synthesis reactions, such as nucleophilic substitution, addition, etc., and occupies an important position in the field of organic synthesis.
[1R- (Endo, Anti) ] -3-Bromo-2-Oxobornane-8-Sulphonic Acid What are the precautions in storage and transportation?
[1R- (inner type, trans) ] -3-bromo-2-oxybornane-8-sulfonic acid, there are many things to pay attention to during storage and transportation.
First words storage. This substance should be placed in a cool, dry and well-ventilated place. Due to its chemical properties, if it is in a high temperature environment, it may cause decomposition and deterioration. Humid gas should also not be contacted to prevent moisture from dissolving and damage its purity and quality. And it should be stored separately from oxidizing agents, reducing agents, alkalis, etc., to avoid chemical reactions. Storage containers are also crucial, and corrosion-resistant materials should be used, tightly sealed to prevent leakage and impurities from mixing.
Second talk about transportation. During transportation, ensure that the container is stable and will not be damaged by shaking and collision. Transport vehicles must have good ventilation conditions to disperse possible volatile gases. At the same time, transport personnel should be familiar with the characteristics of this substance and emergency treatment methods. If the package is damaged during transportation, appropriate measures can be taken quickly to prevent the harm from expanding. In addition, relevant transportation regulations must be followed, and necessary protective equipment and emergency rescue equipment must be equipped to ensure the safety of the transportation process.