(1S)-Camphor-10-Sulfonic Acid

Lingxian Chemical

Specifications

HS Code	193730
Name	(1S)-Camphor-10-Sulfonic Acid
Chemical Formula	C10H16O4S
Molar Mass	232.297 g/mol
Appearance	White to off - white solid
Solubility In Water	Soluble
Melting Point	195 - 202 °C
Optical Rotation	Positive optical rotation due to chiral center
Acidity	Weakly acidic, contains a sulfonic acid group
Chirality	Chiral compound, has a single stereocenter at the 1 - position
Odor	Odorless or very faint odor

Packing & Storage

Packing	(1S)-Camphor - 10 - Sulfonic Acid in 100g pack, suitable for chemical use.
Storage	(1S)-Camphor - 10 - Sulfonic Acid should be stored in a cool, dry place, away from heat sources and direct sunlight. Keep it in a well - sealed container to prevent moisture absorption and contamination. Store it separately from incompatible substances, such as strong oxidizing agents or bases, to avoid chemical reactions that could compromise its quality.
Shipping	(1S)-Camphor - 10 - Sulfonic Acid is shipped in carefully sealed containers, safeguarded against moisture and physical damage. Shipment adheres to strict chemical transport regulations to ensure safe transit.

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General Information

Historical Development

(1S) -camphor-10-sulfonic acid has a unique history in the field of chemistry. Its initial appearance was derived from the study of natural substances by various sages. In the past, chemists studied the transformation of camphor, and in its derivation, they obtained this sulfonic acid.
At that time, although the method of exploration was simple, everyone worked tirelessly. With the passage of time, the technology has advanced, and the method of preparation has gradually refined. From the initial crude extraction to the delicate synthesis, the rise of chemical technology has been seen.
Its use has also increased with the depth of understanding. At the beginning or only an experimental product, it emerged in the field of catalysis, helping many reactions to proceed smoothly. Looking at its development, it is one of the examples of chemical evolution, from ignorance to clarity, step by step to consolidate the wisdom and hard work of predecessors.

Product Overview

(1S) -camphor-10-sulfonic acid is an important compound in organic synthesis. Its properties are white crystalline powder with good solubility.
This compound plays a key role in many chemical reactions. In the field of asymmetric synthesis, it can be used as a chiral catalyst to guide the reaction in a specific chiral direction, greatly improving the optical purity of the target product.
The preparation method, often using natural camphor as the starting material, is prepared by sulfonation and other series of reactions. The reaction process requires precise control of conditions, such as temperature, ratio of reactants, etc., to ensure the purity and yield of the product.
Because of its unique role in organic synthesis, it is widely used in medicine, materials science and many other fields. In pharmaceutical research and development, it helps to synthesize chiral drugs with specific activities, making significant contributions to human health.

Physical & Chemical Properties

(1S) -Camphor-10 - Sulfonic Acid ((1S) -Camphor-10-Sulfonic Acid) is also a chemical compound. Its properties are both physical and chemical. In terms of physical properties, it is often white crystalline powder powder, with a certain degree of melting, which can be determined by its substance. And it has a certain solubility in water, which is the surface of its physical dispersion.
For its chemical properties, its sulfonic acid group is acidic and can react to polyacids. Neutralization of the material can generate a phase. And the specific basis in its structure makes it capable of chiral synthesis in the field of synthesis, and does not cause synthesis to reverse, exhibiting unique chemical activity, which is important for chemical research and engineering.

Technical Specifications & Labeling

(1S) -camphor-10-sulfonic acid is also the essence of transformation. Its technical regulations and identification (commodity parameters) are the focus of the researcher. Looking at this substance, it is unique. The technical regulations are related to the preparation method, from the selection of materials to the control of the process. The material must be pure, and the process must be careful, in order to become a high-quality product.
The identification (commodity parameters) is also critical, such as shape, taste, degree, etc. All need to be clear. The color should be pure, the taste should be correct, and the degree must be standard. The two, the technical regulations and the identification (commodity parameters), complement each other, and are the quality assurance of (1S) -camphor-10-sulfonic acid. The researcher keeps studying it, in order to make the technique better and the logo (product parameters) more accurate, so that this product can be more effective in the world and benefit the public.

Preparation Method

The method of making (1S) -Camphor-10 -Sulfonic Acid is related to the raw materials and production process, reaction steps and catalytic mechanism, as follows.
First take natural camphor as raw material, this is the base of the preparation. React with appropriate sulfating reagents, such as concentrated sulfuric acid, etc. During the reaction, control its temperature, time and reagent dosage. Initially, mix the two, slowly heat up to a moderate level, so that the sulfonic acid group is gradually connected to a specific position of camphor.
In this reaction step, the activity and amount of the sulfating reagent are the key. If the amount is small, the reaction is not complete; if the amount is large, it may cause side reactions. The temperature also needs to be precise. If it is too high, the product will decompose, and if it is too low, the reaction will be slow.
In the catalytic mechanism, a little specific catalyst can be added to help the reaction speed reach equilibrium and improve the yield. And the reaction process must be suitably stirred to make the materials mix evenly and the reaction is uniform. In this way, (1S) -Camphor-10 - Sulfonic Acid can be obtained by this process.

Chemical Reactions & Modifications

There is now a chemical substance, named (1S) - Camphor - 10 - Sulfonic Acid. Its chemical reaction and modification are related to the importance of our research.
This compound has a changeable nature in the reaction environment. At the beginning, it was applied according to the usual method, and the reaction was slow and ineffective. We then thought about changing it, adjusting its temperature and pressure, and making it easy for its solvent.
After a while, it changed. The reaction rate gradually increased, and the quality of the product was also excellent. The reason is that the adjustment of temperature and pressure makes the molecular movement more active, and the ease of solvent promotes the smooth reaction.
From this point of view, chemical reactions are not static, and their conditions are adjusted, their properties are changed, and their products are optimized. This can be evidenced by the study of (1S) -Camphor-10 -Sulfonic Acid, and it is also a lesson for the study of other things.

Synonyms & Product Names

(1S) -camphor-10-sulfonic acid, its name is also unique and the quality is the same. In the transformation environment, this agent is often known by a different name. Or L-camphor sulfonic acid, or called natural camphor sulfonic acid, although the names are different, they all refer to this thing.
It is widely used and widely used in various reactions of transformation, often used as a catalyst to promote its action. Looking at ancient books, although this thing is not directly described, today's people study its practicality, explore its origin, and know its importance in the process of transformation.
Merchants sell it under different names, or take a good name to show its superiority, but it is originally (1S) -camphor-10-sulfonic acid. Those who use it should be clear about its nature, and should not be confused by different names, so as to achieve the wonders of use, which will benefit both the research and the industry.

Safety & Operational Standards

(1S) -Camphor-10-sulfonic acid is an important chemical substance. During its production and use, safety and operating practices are of paramount importance.
In terms of safety, this substance has certain chemical activity. When storing, be sure to store in a cool, dry and well-ventilated place, away from fire and heat sources to prevent accidents. Due to its irritation to the skin, eyes and respiratory tract, operators should wear appropriate protective equipment, such as protective gloves, goggles and masks, to ensure their own safety. If accidentally touching the skin, rinse with plenty of water immediately; if entering the eyes, rinse with running water immediately and seek medical attention.
In terms of operating specifications, accurate weighing and configuration are indispensable in the experiment or production process. The reaction needs to be carried out according to a specific ratio and process, and the reaction conditions such as temperature, pressure and reaction time should be strictly controlled. During the reaction process, close attention should be paid to the reaction phenomenon. If there is any abnormality, immediate corresponding measures should be taken. After the experiment is completed, properly dispose of the remaining substances, follow the environmental protection requirements, and do not discard them at will to avoid polluting the environment.
When using (1S) -camphor-10 -sulfonic acid, strictly abide by the safety and operating standards to ensure the safety of personnel, the smooth operation of the experiment and the environment are not damaged. This is the principle that chemical workers should uphold, and it is also the basis for ensuring the sustainable development of chemical research and production.

Application Area

(1S) -camphor-10-sulfonic acid is also a chemical compound. Its use is useful in all fields. In the context of synthesis, it can be used as a highly efficient catalyst. It can promote the reaction rate, increase its rate, and has high performance, so that the quality of the material can be improved.
In the field of synthesis, it also has its work. Or it can be used as a raw material for the synthesis of materials to assist in the research of new materials. With its unique properties, or it can affect the activity and solubility of the material.
In the field of material science, it also works. Or it can be used as a special material, and the material can be used with new characteristics, such as improving the quality and performance of the material. In addition, (1S) -Camphor-10 - Sulfonic Acid has its unnegligible value in all multi-purpose domains, and the development of each domain is deduced.

Research & Development

In recent years, I -Camphor-10-Sulfonic Acid in (1S) and devoted myself to the research. Its unique nature, wide range of uses, and promising in various fields.
At the beginning, the method of preparing it encountered various problems. The choice of raw materials and the control of the proportion need to be cautious. After repeated tests, a better method can be obtained, and the yield gradually increases.
Then, explore its application. In organic synthesis, it can be used as a catalyst to promote the progress of the reaction and increase the purity of the product. In drug research and development, it also has potential ability, or can help the stability of active ingredients.
Looking to the future, I want to explore its use and study its novelty. We hope to work together with our colleagues to make it shine in more fields, contribute to the progress of research and development, and promote the long-term development of this product.

Toxicity Research

Today, there is a thing named (1S) -Camphor-10 - Sulfonic Acid, and our generation focuses on the study of poisons. The investigation of this substance's toxicity is also related to the health of everyone and the safety of the environment.
Examine this agent in detail, and it is necessary to clarify its solubility in different media, the speed of diffusion, and the changes caused by contact with other substances. Observe its entry into the living body, observe the changes in the functions of the viscera, and the differences in physiological signs.
Also explore its circulation in the environment, soil, water flow, and atmosphere, all of which cannot be ignored. Only by studying the way of transmission of this poison and the law of transformation can we determine preventive measures to reduce its harm to the invisible. Poison research is a long way to go, and we must devote all our efforts to protect the safety of all kinds.

Future Prospects

In today's view (1S) -Camphor-10-Sulfonic Acid, this product has extraordinary potential. In the field of chemical industry, it may be a new path. The unique characteristics of this material can help to synthesize exquisite materials, and it is expected to emerge in the future of material innovation.
At the level of medical research, its pharmacological activity may need to be further explored. With time, after careful research, it may become a cure for new diseases and a good medicine for the well-being of patients. The way of scientific research, although full of thorns, but we chemical researchers, should have tenacity. With unremitting exploration, the (1S) -Camphor-10-Sulfonic Acid will bloom brilliantly, and in the unfinished scientific journey, it will pave the way for prosperity, benefit future generations, live up to the trust of the times, and light up the light of hope for the unknown domain. This is our grand wish for the future.

Frequently Asked Questions

What is the chemical structure of -Camphor-10-Sulfonic Acid?

(1S) -camphor-10-sulfonic acid, its chemical structure is quite unique. This is a chiral compound, closely related to camphor.
From its structural view, it is based on the skeleton of camphor. The skeleton of camphor is presented as a rigid double-ring structure, just like the exquisite ring jade pendant in ancient times. It is cleverly spliced by two connected six-membered rings and a five-membered ring, and the configuration is stable, just like heaven.
In this structure, a sulfonic acid group (-SO 🥰 H) is introduced at position 10, which is like a delicate accessory attached to the jade pendant, giving the whole molecule special chemical properties. In the sulfonic acid group, the sulfur atom is connected to three oxygen atoms by a special chemical bond, and one of the oxygen atoms is bonded to the hydrogen atom, which makes the group acidic and can dissociate hydrogen ions under suitable conditions, as if it can release flexible energy.
Furthermore, " (1S) " indicates that the carbon atom of the compound at position 1 has a specific three-dimensional configuration, just like the unique texture carefully carved at a specific location, which determines its arrangement in space. This three-dimensional configuration has a profound impact on its chemical and physical properties and plays a key role in many chemical reactions and biological activities. Such a unique chemical structure makes (1S) -camphor-10-sulfonic acid play an important role in the fields of asymmetric synthesis and chiral catalysis.

(1S) -Camphor-10-Sulfonic Acid is commonly used in which chemical reactions

(1S) -camphor-10-sulfonic acid is often a key agent in many organic reactions. This is a chiral sulfonic acid compound with unique spatial structure and acidic characteristics, so it has made outstanding contributions to the field of asymmetric synthesis.
In asymmetric catalytic reactions, (1S) -camphor-10-sulfonic acid often acts as a chiral adjuvant or chiral catalyst. For example, in asymmetric Foucault reactions, it can cooperate with metal catalysts to create an asymmetric reaction environment and induce the reaction to proceed in a specific chiral direction, so that high-optical purity products can be efficiently obtained, which is of great significance in the fields of drug synthesis and total synthesis of natural products. Because many active pharmaceutical ingredients require specific chiral configurations to exhibit the best pharmacological activity.
Furthermore, in the esterification reaction, (1S) -camphor-10-sulfonic acid is also useful. Its acidic properties can catalyze the esterification of alcohols and carboxylic acids. Compared with traditional inorganic acid catalysts, its chiral environment may affect the stereochemistry of esterification products, especially when preparing chiral esters.
In addition, in some nucleophilic substitution reactions, (1S) -camphor-10-sulfonic acid can activate the substrate, promote the reaction to occur more easily, and because of its chirality, or guide the nucleophilic reagents to attack from a specific direction, achieve stereoselectivity control.
In conclusion, (1S) -camphor-10-sulfonic acid provides a powerful means for chemists to prepare high-purity chiral compounds due to its chiral and acidic properties in many reactions in organic synthesis, and plays an important role in the field of modern organic synthetic chemistry.

(1S) What are the physical properties of -Camphor-10-Sulfonic Acid?

(1S) -camphor-10-sulfonic acid is an organic compound. It has many physical properties and is hereby referred to as Jun Chenzhi.
First of all, its properties are often in the state of white crystalline powder. It is clean and uniform in appearance. Under sunlight, it may have a slight luster, like a fine pearl.
When it comes to melting point, the melting point of (1S) -camphor-10-sulfonic acid is quite specific, about 197-201 ° C. This temperature characteristic is like its unique "mark". When heated to this range, the substance gradually melts from solid to liquid, and the arrangement and interaction between its molecules also change accordingly.
As for solubility, it has a certain solubility in water. Water is the source of all things, and many substances go hand in hand with it. (1S) -camphor-10-sulfonic acid encounters water, and some molecules can be evenly dispersed to form a uniform solution. This property makes it able to play a corresponding role in many chemical reactions or applications involving the aqueous phase. And in some organic solvents, such as ethanol, acetone, etc., it also has a certain degree of dissolution, which can be miscible with these organic solvents and expand its application range in organic systems.
Its density is also an important physical property. Although the specific value or the measurement conditions are slightly different, it is roughly within a specific range. This density determines its settling and floating behavior in different media. In actual production and application scenarios, it affects the mixing and separation of materials.
(1S) -camphor-10-sulfonic acid has optical activity, which is due to the asymmetry of its molecular structure. Under polarized light, polarized light can rotate, which is a unique optical phenomenon that cannot be ignored in the fields of optical materials and chiral drug synthesis.

(1S) What is the market price range of -Camphor-10-Sulfonic Acid?

The price of (1S) -camphor-10-sulfonic acid in the market often varies depending on the purity of the product, the quantity, and the state of supply and demand. It is not easy to find its exact price.
Looking at the changing state of the city in the past, the price of this product fluctuates quite a lot. In terms of quality, those with high purity must be expensive than those with low purity. Cover high purity (1S) -camphor-10-sulfonic acid, which has better effects in the fields of medicine and fine chemicals, so the seeker is willing to pay a high price to buy it.
Furthermore, the size of the quantity also affects the price. If you buy in large quantities, the seller often gives discounts to promote more sales, and the price of the order volume is low at this time; if you buy in small quantities, the supplier will consider the cost of operation, and the price may be high.
And the market supply and demand situation is the key to the price. When supply exceeds demand, the seller will sell his goods, and the price will tend to drop; if the demand is too much, the buyer will compete for the purchase, and the price will rise.
In the past, the price per gram in the city ranged from a few yuan to tens of yuan. However, this is only a rough number. Today, due to the change in the price of chemical raw materials, the new revolution in technology, and the change in trade regulations, the price is no longer comparable to what it used to be. To know the current accurate price, consult chemical raw material suppliers and chemical trading platforms for details.

(1S) What are the common synthesis methods of -Camphor-10-Sulfonic Acid?

(1S) -camphor-10-sulfonic acid is an important compound in organic synthesis. There are several common synthesis methods.
First, natural camphor is used as the starting material. Natural camphor comes from a wide range of sources and is relatively convenient to take. First, natural camphor is reacted with fuming sulfuric acid under specific conditions. In this process, fuming sulfuric acid is used as a sulfonation reagent to make camphor molecules sulfonate, and then (1S) -camphor-10-sulfonic acid is formed. However, this method needs to pay attention to the control of the reaction conditions. Because fuming sulfuric acid is highly corrosive, if the conditions are not appropriate, it is easy to cause side reactions and affect the purity and yield of the product. The temperature during the reaction should be controlled in a moderate range, and the reaction time should also be precisely controlled to improve the quality of the product.
Second, through the chemical synthesis route. With a suitable organic compound as the starting material, the target molecule is constructed through a multi-step reaction. For example, a specific olefin compound can be added to a specific reagent to generate an intermediate product, followed by a series of reactions such as functional group conversion of the intermediate product, and finally (1S) -camphor-10-sulfonic acid is obtained. Although this method is complicated, the reaction can be precisely designed and regulated according to the needs, which helps to improve the optical purity and yield of the product. However, this method requires high reaction equipment and technology, and the reaction conditions at each step need to be strictly controlled during the synthesis process to ensure the smooth progress of the reaction.
Third, biosynthesis is also a way. The synthesis of (1S) -camphor-10-sulfonic acid is achieved by the catalytic action of specific microorganisms or enzymes. The biosynthesis method has the advantages of green environmental protection and high selectivity, and can react under milder conditions to reduce environmental pollution. However, it also faces challenges, such as harsh microbial culture conditions, the stability and activity of enzymes need to be carefully regulated, and the efficiency of biosynthesis needs to be further improved. In practical applications, the microbial culture conditions and enzyme catalytic reaction conditions need to be optimized to improve the effect of biosynthesis.