Products

(1S)-(+)-Camphor-10-Sulfonic Acid

Lingxian Chemical

Specifications

HS Code

580834

Chemical Formula C10H16O4S
Molar Mass 232.297 g/mol
Appearance white to off - white crystalline powder
Solubility In Water soluble
Optical Rotation +192° to +198° (c = 4, ethanol)
Melting Point 195 - 200 °C
Pka Value 1.61
Density 1.31 g/cm³
Flash Point 193.2 °C
Odor odorless
Packing & Storage
Packing 100g of (1S)-(+)-Camphor - 10 - Sulfonic Acid in a sealed, labeled chemical - grade package.
Storage (1S)-(+)-Camphor - 10 - Sulfonic Acid should be stored in a cool, dry place, away from direct sunlight. Keep it in a tightly - sealed container to prevent moisture absorption and contact with air, which could potentially affect its purity and stability. Store it separately from incompatible substances, such as strong bases, to avoid chemical reactions.
Shipping (1S)-(+)-Camphor - 10 - Sulfonic Acid is shipped in well - sealed containers, ensuring protection from moisture and contamination. It adheres to chemical shipping regulations for safe transportation.
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(1S)-(+)-Camphor-10-Sulfonic Acid
General Information
Historical Development
(1S) - (+) -camphor-10-sulfonic acid is also a product of chemical refining. The historical evolution of its substances is very interesting. In the past, chemical research was not as detailed as it is today, and it was difficult to explore such substances. At the beginning, I only knew its properties a little, but after unremitting study by various sages, I gradually understood its rationale. Since the beginning of observing its shape and quality, to knowing its chemical structure, generations of scholars have devoted themselves to it. Or I have occasionally found clues in experiments, or I have obtained its true meaning through repeated deduction. As time passes, technology advances, and the preparation method becomes more and more exquisite. Therefore, the cognition and application of (1S) - (+) -camphor-10 -sulfonic acid has been expanded unprecedented, and it has gradually become more important in various fields of chemistry, laying a foundation for future research and seeking new paths.
Product Overview
(1S) - (+) -camphor-10-sulfonic acid is a compound that has attracted much attention in the field of organic synthesis. Its shape is mostly white crystalline powder with unique optical rotation, which is of great significance in many asymmetric synthesis reactions.
This compound has a wide range of uses in chemical research and is often used as a chiral catalyst to assist in asymmetric reactions, which can effectively improve the optical purity of the product. In the field of medicinal chemistry, it helps in the synthesis of chiral drugs and provides key support for the development of new drugs with high efficiency and low toxicity.
The preparation method is obtained by a series of reactions such as sulfonation with camphor as the starting material through specific chemical transformation. The preparation process requires fine control of the reaction conditions to ensure the purity and optical activity of the product.
(1S) - (+) -camphor-10-sulfonic acid continues to play an important role in the process of chemical research, contributing to the development of organic synthesis and related fields.
Physical & Chemical Properties
(1S ) -( + ) - camphor-10-sulfonic acid is also a chemical substance. Its physical and chemical properties can be investigated. Looking at its color, it is often pure, or crystalline, pure and transparent. On its melting point, there is a certain number inherent, which is the key to identification. Solubility also has its own rules, soluble in some solvents, not in others, all of which are related to the molecular structure. Its unique optical rotation, (1S ) -( + ) state, gives it optical activity, in many chemical processes, this characteristic may lead to different reaction paths. And its stability, in different temperatures and humid environments, or changes, this is the weight of chemical research, to clarify its nature, can make good use of it.
Technical Specifications & Labeling
(1S ) - ( + ) - Camphor - 10 - Sulfonic Acid is a chemical product we have painstakingly studied. Its process specifications and identification (commodity parameters) are related to the quality and application of this product.
In terms of process specifications, from the selection of raw materials, pure and good products must be obtained to maintain the foundation. The preparation method needs to follow the precise process, temperature control, speed regulation, timing, and no difference in the pool. If in the reactor, high or low temperature affects the purity of the product.
In terms of identification (commodity parameters), the purity needs to be marked in detail, which is the key. There is also an appearance description, the color should be pure, and the state must be uniform. And its physical and chemical properties parameters, such as melting point, boiling point, etc., should also be clear to help users make good use of it. In this way, (1S ) - ( + ) - Camphor - 10 - Sulfonic Acid can achieve excellent performance and develop its effectiveness in various fields.
Preparation Method
(1S) - (+) -camphor-10-sulfonic acid, the method of preparation, is related to the raw materials and production process, reaction steps, and catalytic mechanism. The raw material is well-selected camphor, supplemented by suitable reagents. In the production process, temperature, pressure and other conditions are controlled according to the appropriate process. The reaction steps are rigorous, and the specific reagents and camphor co-react first, following the established order, so that the molecules can be cleverly rearranged and converted. In the catalytic mechanism, an efficient catalyst is selected to promote the reaction speed, increase the yield and purity. In this way, high-quality (1S) - (+) -camphor-10-sulfonic acid can be obtained, which is used in various fields.
Chemical Reactions & Modifications
Taste the wonders of chemical industry, with endless changes. In (1S) - (+) -Camphor - 10 - Sulfonic Acid, the chemical reaction and variability of this compound are the essence of research.
In the past, many discoveries have been made to explore the reaction of this acid. In a specific medium, it can combine with various reagents and undergo unique chemical changes. The speed of reaction varies depending on temperature, pressure and catalysis.
And its variability is amazing. After different processes, the molecular structure can be fine-tuned and the properties can be changed. Or enhance its stability, or change its solubility, opening up new avenues for chemical applications.
Today, we should continue the wisdom of our predecessors, further study its reaction mechanism, and optimize the method of variability, so as to make this compound play a greater role in the fields of medicine, materials, etc., and contribute to the progress of chemistry.
Synonyms & Product Names
(1S) - (+) -camphor-10-sulfonic acid is an important material for chemical research. Its aliases are many, all related to camphor sulfonic acid. This compound is widely used in the field of organic synthesis, often as a chiral catalyst to assist asymmetric synthesis reactions and obtain products of specific configurations.
It is also sold in the market under the name of (1S) - (+) -camphor-10-sulfonic acid and is used by many scientific researchers. It plays a key role in many fields such as medicinal chemistry and materials science. Through delicate chemical reactions, it can be converted into various derivatives to meet different scientific research needs. Therefore, the aliases and trade names of (1S) - (+) -camphor-10-sulfonic acid, although expressed differently, actually refer to the same substance, which plays an indispensable role in the process of chemical research.
Safety & Operational Standards
(1S) - (+) -camphor-10-sulfonic acid is an important chemical substance. During its production and use, safety and operating practices are of paramount importance.
In terms of safety, this substance has specific chemical properties or has potential effects on the human body and the environment. When in contact, avoid direct contact with the skin and eyes. If it accidentally touches the skin, rinse with plenty of water immediately. If it enters the eyes, rinse quickly and seek medical treatment. Inhalation of dust or vapor may also be harmful. The working environment should be well ventilated. If necessary, wear appropriate protective equipment, such as masks.
In terms of operating instructions, store in a cool, dry and ventilated place, away from fire sources and oxidants. The use process must be precisely operated, and the dosage must be strictly controlled according to the experimental or production requirements. In the synthesis reaction, the established reaction conditions and procedures must be followed to ensure a smooth and efficient reaction. The treatment of reaction products must also meet environmental protection requirements to avoid pollution to the environment. In short, only by strictly following safety and operating standards can the effective use of (1S) - (+) - camphor-10-sulfonic acid be ensured, while ensuring the safety of personnel and the friendliness of the environment.
Application Area
(1S) - (+) -camphor-10-sulfonic acid has its own extraordinary properties in many application fields. In the field of chemical synthesis, it can be used as an efficient chiral catalyst to assist asymmetric synthesis reactions and obtain products with high optical purity. In the process of drug research and development, it can participate in the preparation of specific drug intermediates, which can affect the drug activity and efficacy with its unique chiral structure. In the field of materials science, it can be used to prepare chiral materials, endowing materials with specific optical and electrical properties. All these applications demonstrate the key value of (1S) - (+) -camphor-10-sulfonic acid in various fields, and it is an indispensable chemical substance.
Research & Development
Modern chemistry is advanced, and all kinds of substances are studied by scholars. (1S) - (+) -Camphor - 10 - Sulfonic Acid This compound is also the focus of our research.
The preparation method requires fine operation, and the reaction conditions at each step need to be carefully regulated. From the selection of raw materials to the temperature and time of the reaction, the quality and quantity of the product are all related.
During the research process, we also observed its characteristics, and recorded the changes in different environments in detail. We hope to clarify its mechanism and optimize the production method.
And this compound has a wide range of applications and has potential in various fields such as medicine and chemical industry. We should make unremitting efforts to promote its development, with the hope that it can be used by the world and benefit people.
Toxicity Research
The toxicity of (1S ) -(+) - Camphor - 10 - Sulfonic Acid is related to people's health and cannot be ignored. We observe its impact on various organisms with a rigorous method. In experiments, we see that when it is applied to insects, the movement of insects gradually slows down and the vitality seems to decline; when it is used for plants and trees, its growth situation is also different, or the leaf color changes, or the stem length is blocked. From this point of view, (1S ) -(+) - Camphor - 10 - Sulfonic Acid is toxic. Although it may be useful in industry, when it is used, it is necessary to be cautious and carefully observe the harm it causes to the surrounding environment and people, so as to ensure that nothing goes wrong. Do not let poisons be a disaster to the world and cause endless harm.
Future Prospects
(1S) - (+) -camphor-10-sulfonic acid is becoming increasingly important in today's chemical research. In the past, our understanding of it was still shallow, but with the advance of science and technology, its potential is gradually revealed.
In today's world, chemical processes are becoming more and more exquisite, and (1S) - (+) -camphor-10-sulfonic acid has emerged in many fields. In the way of drug synthesis, it may be used as a key agent to assist in the development of new drugs and benefit patients. In the process of material science, it may be able to change the properties of materials and make them more widely used.
Looking to the future, we expect that (1S) - (+) -camphor-10-sulfonic acid will surely shine. Scientists may be able to take advantage of its uniqueness to open up new horizons. In the field of catalytic reactions, there may be deeper research to increase the efficiency of reactions and reduce energy consumption. In the industry of fine chemicals, it may become a key material and produce excellent quality products. In short, the prospect of (1S) - (+) - camphor-10-sulfonic acid is like the early morning light, full of hope, and the future development is really waiting to be seen.
Frequently Asked Questions
(1S) - (+) What are the main uses of -Camphor-10-Sulfonic Acid?
(1S) - (+) -camphor-10-sulfonic acid is an organic compound that has important uses in many fields.
In the field of organic synthesis, it often acts as a chiral catalyst. Due to its unique chiral structure, it can efficiently guide the reaction towards a specific chiral direction in asymmetric synthesis reactions, resulting in high optical purity products. For example, in catalytic asymmetric reduction, alkylation and other reactions, it can precisely regulate the stereochemistry of the reaction, greatly increase the enantiomer excess value of the product, and is of great significance for the preparation of drugs and natural products with specific chiral configurations.
In the pharmaceutical industry, (1S) - (+) -camphor-10-sulfonic acid is also very critical. In the pharmaceutical process, it is often necessary to obtain compounds with a single chiral configuration because of their different chiral isomers or very different physiological activities. This compound can catalyze specific reactions to assist in the synthesis of chiral pure pharmaceutical intermediates, thereby promoting the development and production of new drugs.
In addition, in the field of materials science, it may be involved in the preparation of some functional materials. By interacting with other substances, the material is endowed with specific chiral-related properties, such as chiral optical properties, to expand the application of materials in optical devices, sensors, etc.
In summary, (1S) - (+) -camphor-10-sulfonic acid, with its chiral properties, plays an important role in many fields such as organic synthesis, pharmaceuticals, and materials science, and is of great significance for promoting technological progress and innovation in related fields.
What are the physical properties of (1S) - (+) -Camphor-10-Sulfonic Acid
(1S ) - ( + ) - camphor-10-sulfonic acid is an organic compound with unique physical properties. Its properties are white crystalline powder, which is pure and fine in quality, just like the first snow in winter, delicate and pure.
This substance is very soluble in water, quietly dispersed in water, just like the ice and snow that melt in rivers, invisible and formless, into a uniform state. At the same time, it also has good solubility in organic solvents such as alcohols, and it fuses with alcohols, just like friends meet, and can quickly form a uniform and stable system.
Its melting point is quite critical, about 197-201 ℃. When the temperature gradually rises to this point, the substance is like a sleeping thing waking up, gradually transforming from a solid state to a liquid state, completing the phase transition. This melting point characteristic can be used to identify its purity. If the purity is extremely high, the melting point will accurately fall in this range. A little impurity is incorporated, and the melting point may be deviated.
Its optical rotation is also a significant feature. As a (1S ) - ( + ) configuration, it has positive optical rotation. Viewed under a polarized light microscope, the light rays rotate in a specific direction through their action, just like the dancer dancing on the stage according to a specific trajectory, showing the unique optical charm. This optical rotation property is of great significance in many fields, such as drug synthesis, which can be used to ensure the correct configuration of drug molecules, which may have different physiological activities due to different configurations.
In addition, (1S ) - ( + ) - camphor-10-sulfonic acid also has certain hygroscopicity. In humid air, it is like a sponge absorbing water, quietly absorbing water, causing its own weight to increase and appearance to change. When storing, pay attention to the ambient humidity to prevent moisture absorption from affecting its quality and performance.
Applications of (1S) - (+) -Camphor-10-Sulfonic Acid in Synthesis
(1S) - (+) -camphor-10-sulfonic acid is widely used in organic synthesis.
First, in the field of chiral catalysts, it shows extraordinary utility. In many asymmetric synthesis reactions, this substance can act as a chiral catalyst, which greatly affects the stereochemical process of the reaction. Taking asymmetric reduction reactions as an example, (1S) - (+) -camphor-10-sulfonic acid can be combined with metal catalysts to construct chiral catalytic systems. In this way, ketones can be efficiently and selectively reduced to specific alcohols, providing key chiral intermediates for chiral drugs, total synthesis of natural products and other fields.
Second, in the field of chiral resolution, it also has important applications. Due to its unique chiral structure, (1S) - (+) -camphor-10-sulfonic acid can form a diastereomeric salt with the enantiomers in racemates. Due to differences in physical properties, such as different solubility, this salt can achieve enantiomer resolution by means of recrystallization. For example, by splitting some racemic amine compounds, high-purity single chiral amines can be obtained by this method, which can meet the needs of chiral compounds in the pharmaceutical, pesticide and other industries.
Third, in terms of organic synthesis reaction promoters, (1S) - (+) -camphor-10-sulfonic acid can also play a role. In some organic reactions, the addition of this substance can speed up the reaction rate and improve the reaction yield. Like esterification reaction, it can enhance the reactant activity and promote the reaction to proceed more smoothly, thereby increasing the output of ester compounds, which is of great significance in the synthesis of fine chemical products.
What are the storage conditions for (1S) - (+) -Camphor-10-Sulfonic Acid?
(1S ) - ( + ) - camphor-10-sulfonic acid is an important chemical substance. Its storage conditions are crucial to the quality and effectiveness of this substance.
This substance should be stored in a cool, dry and well-ventilated place. A cool environment can avoid changes in its properties due to high temperature. High temperature can easily lead to chemical reactions, or cause it to decompose and deteriorate, damaging its chemical properties. A dry environment is also indispensable, because moisture is easy to interact with the substance, or make it deliquescent, affecting the purity and stability. And good ventilation can disperse harmful gases that may be generated in time, and maintain the fresh air in the storage space to prevent local gas accumulation from causing danger.
In addition, when storing, keep away from fire and heat sources. Fire and heat sources may cause combustion or explosion. Because of their specific chemical activity, they can be exposed to open flames, hot topics or violent reactions. And should be stored separately from oxidizing agents and alkalis, etc., and cannot be mixed. Due to the contact of the substance with oxidizing agents, or oxidation reactions; encounters with alkalis, or reactions such as acid-base neutralization, its chemical structure and properties will change.
Where it is stored, suitable materials should also be prepared to contain the leakage. If it is accidentally leaked, it can be dealt with in time to avoid polluting the environment and preventing damage to personnel and equipment. In conclusion, following the above storage conditions can ensure the quality and safety of (1S ) - ( + ) - camphor-10-sulfonic acid, so that it can play its due role in various applications.
What are the preparation methods of (1S) - (+) -Camphor-10-Sulfonic Acid
The preparation method of (1S) - (+) -camphor-10-sulfonic acid has been known for a long time. The method is mostly based on the ancient books, and after many practices, the exquisite method can be obtained.
First, use natural camphor as the starting material, which is a gift from nature. Take an appropriate amount of camphor first and put it in a clean vessel. Mix with sulfuric acid and other reagents in an appropriate proportion. It is necessary to carefully control the temperature to make the reaction smooth and orderly. If the temperature is too high, it is easy to cause side reactions to cluster and damage the purity of the product. In the meantime, observe the reaction image, and wait for its color change and mass transfer to know the process of the reaction.
Second, other related compounds are also used as the starting point. By means of chemical techniques, molecules can be rearranged and transformed. After various reaction steps, such as esterification, hydrolysis, etc. Between each step, it is appropriate to wash in detail to remove its impurities. The purity of the solvent and reagent used is related to the quality of the product.
Third, when preparing, the technique of separation and purification is indispensable. Or use the method of crystallization to precipitate the product from the solution according to its solubility. Or use the technique of chromatography to precisely separate and obtain pure (1S) - (+) - camphor-10-sulfonic acid. This process requires patience and meticulousness, and there must be no slack.
Preparation of (1S) - (+) -camphor-10-sulfonic acid requires familiarity with chemical principles and adherence to operating regulations in order to achieve the purpose of preparing excellent products.