What is the chemical structure of 2,2 '- (E) -Ethene-1,2-Diylbis [5- (4-Phenyl-2H-1,2,3-Triazol-2-Yl) Benzenesulfonic Acid]?
This is a compound named 2,2 '- (E) -Ethene-1,2-Diylbis [5- (4-Phenyl-2H-1,2,3-Triazol-2-Yl) Benzenesulfonic Acid]. To understand its chemical structure, let me tell you in detail.
"2,2' - (E) -Ethene-1,2-Diylbis" indicates that this compound has an ethylene-1,2-diyl group in the (E) configuration as a connecting group. The double bond configuration of this vinyl group is trans (E type), just like the ancient mortise and tenon, which is cleverly connected to other parts.
"[5- (4 - Phenyl - 2H - 1,2,3 - Triazol - 2 - Yl) Benzenesulfonic Acid]" reveals that the compound has a benzenesulfonic acid structure connected at both ends. At the 5th position of the benzene ring, there is 4 - phenyl - 2H - 1,2,3 - triazole - 2 - group connected. The benzene ring is as stable as a cornerstone, and the phenyl and triazole groups connected to it each have unique chemical properties. Phenyl has aromatic properties, similar to ancient elegance, and exudes a unique charm; the triazole ring also has special reactivity. The sulfonic acid group (-SOH) imparts hydrophilicity to the compound, as if it can divert water, giving it a unique performance in water.
Overall, in this compound structure, trans vinyl is used as a bridge, and there are benzene sulfonic acid structures containing phenyl and triazolyl at both ends. Each part is related to each other to form a unique chemical structure, which is just like a well-constructed ancient building. All parts are indispensable and cooperate to show unique chemical properties.
What are the main physical properties of 2,2 '- (E) -Ethene-1,2-Diylbis [5- (4-Phenyl-2H-1,2,3-Triazol-2-Yl) Benzenesulfonic Acid]?
This is called 2,2 '- (E) -Ethene-1,2-Diylbis [5- (4-Phenyl-2H-1,2,3-Triazol-2-Yl) Benzenesulfonic Acid], its main physical properties are as follows:
This product may have specific solubility. In polar solvents, because it contains sulfonic acid groups, which are strong polar groups, it may exhibit good solubility and can be dissolved in polar solvents such as water. The Gain sulfonic acid group can interact with water molecules to form hydrogen bonds, etc., thereby promoting dissolution.
When it comes to the melting point, given that its molecular structure contains rigid structural units such as benzene rings and triazole rings, and the intermolecular interaction force is strong, the melting point is expected to be quite high. The rigid structure restricts the movement of molecules, and requires high energy to destroy the lattice and cause the melting point to rise.
In terms of appearance, the conjugate system based on the many aromatic rings in its structure, or a white to light yellow solid powder. The conjugate system affects the absorption and reflection of light, which makes the appearance characteristic.
The density of this substance is relatively large due to the large number of atoms in the molecule and the close arrangement. The complex structure composed of many atoms has a high mass per unit volume, resulting in a high density. In terms of stability, the conjugate system of benzene ring and triazole ring confers certain stability to the structure, and the sulfonic acid group is relatively stable. Without special chemical environment or conditions, this substance may remain stable under normal conditions and is not prone to self-decomposition and other reactions.
What are the synthesis methods of 2,2 '- (E) -Ethene-1,2-Diylbis [5- (4-Phenyl-2H-1,2,3-Triazol-2-Yl) Benzenesulfonic Acid]?
To prepare 2%2C2%27-%28E%29-Ethene-1%2C2-Diylbis%5B5-%284-Phenyl-2H-1%2C2%2C3-Triazol-2-Yl%29Benzenesulfonic Acid% 5D, the following method can be followed.
First, the appropriate raw materials are obtained, which contain benzenesulfonic acids, phenyl triazoles and compounds with vinyl bis-functional groups. By organic synthesis, in order to form bonds between the raw materials, the appropriate reaction conditions should be selected.
The reaction can be catalyzed by transition metals first, such as the copper-catalyzed azide-alkynyl cycloaddition reaction (CuAAC). In this reaction, the alkynyl-containing benzenesulfonic acid derivative and the azido-containing phenyltriazole derivative are used as reactants, and the copper salt is used as the catalyst, and the ligand is assisted. In a suitable solvent, such as dimethylformamide (DMF) or dichloromethane, etc., the temperature is controlled between room temperature and 50 ° C. The reaction number. This step aims to form a 1,2,3-triazole ring structure.
Then, a vinyl bis-functional group compound is used to react with the obtained triazole-containing benzenesulfonic acid derivative. This reaction can be achieved by a coupling reaction, such as a palladium-catalyzed coupling reaction. Select an appropriate palladium catalyst, such as tetra (triphenylphosphine) palladium (0), ligand-assisted, in an alkaline environment, with toluene or dioxane as a solvent, heat up to 80-100 ° C, and react for several times, so that the vinyl group and the benzene ring are bonded to obtain the target product 2%2C2%27-%28E%29-Ethene-1%2C2-Diylbis%5B5-%284-Phenyl-2H-1%2C2%2C3-Triazol-2-Yl%29Benzenesulfonic Acid% 5D.
After each step of the reaction, the product needs to be purified by column chromatography or recrystallization to remove impurities and obtain a high-purity product. In this way, after multi-step reaction and purification, the desired target compound can be obtained.
In what fields is 2,2 '- (E) -Ethene-1,2-Diylbis [5- (4-Phenyl-2H-1,2,3-Triazol-2-Yl) Benzenesulfonic Acid] used?
There is a product called 2,2 '- (E) -Ethene-1,2-Diylbis [5- (4-Phenyl-2H-1,2,3-Triazol-2-Yl) Benzenesulfonic Acid]. This product is useful in many fields.
In the context of materials science, it can be used as a key component in the construction of materials with special properties. Due to its unique molecular structure, it may endow materials with specific optical and electrical properties. For example, it can be used to prepare materials with special photochromic or electrical conductivity properties, which can contribute to the manufacture of new display devices, electronic components, etc.
In the field of biomedicine, it can also be used. Because its structure contains specific groups, it can be specifically bound to biomolecules. Or it can be used as a biological probe to accurately identify specific biomarkers and help early diagnosis of diseases; or it can participate in the construction of drug delivery systems, so that drugs can act more accurately on the lesion site and improve the therapeutic effect.
In the realm of chemical synthesis, it is often an important intermediate in organic synthesis. With its complex and orderly structure, chemists can use it to build more complex and delicate organic molecules, expand the boundaries of organic synthesis chemistry, and create more compounds with novel structures and functions, providing a rich material basis for new drug development and material innovation. In short, this substance shows great potential in many fields, and it is an important substance that cannot be underestimated.
What are the precautions in the preparation of 2,2 '- (E) -Ethene-1,2-Diylbis [5- (4-Phenyl-2H-1,2,3-Triazol-2-Yl) Benzenesulfonic Acid]?
When preparing 2,2 '- (E) -Ethene-1,2-Diylbis [5- (4-Phenyl-2H-1,2,3-Triazol-2-Yl) Benzenesulfonic Acid], many things need to be paid attention to. The purity of the first raw material must be excellent. If impurities exist, the reaction process will be disrupted and the product will be impure. The selection of materials should also be cautious. If the quality is not good, the longitudinal reaction will be correct, and the product will not meet expectations.
The reaction conditions are extremely critical. Temperature should be precisely controlled, whether high or low, which affects the reaction rate and yield. From the ancient perspective, the mastery of the heat is related to success or failure, and the same is true. The pH value should not be underestimated. At different stages, the suitable pH is different, and the deviation will block the reaction.
The choice of catalyst is also important. It can promote the reaction, but the type and dosage need to be considered, more is too much, and less is insufficient catalysis. The reaction time should also be paid attention to. If it is too short, the reaction will not be completed, and if it is too long or side reactions will occur.
The operation process should be rigorous. Mixing raw materials needs to be uniform, and the stirring rate affects mass transfer and heat transfer, which is related to the reaction effect. When separating and purifying, the method can be used properly to obtain pure products. Extraction, crystallization and other methods have their own suitability, and if they are used incorrectly, all efforts will be wasted.
The experimental environment is also affected. It is appropriate to clean and dry, and moisture and impurities can disturb the reaction. From beginning to end, you need to be careful. If you make a mistake, you will lose everything. Only in this way can you make a good product.