What is the chemical structure of 2- (4-Pyridyl) Ethanesulfonic Acid?
2-%284-Pyridyl%29Ethanesulfonic Acid is 2- (4 -pyridyl) ethanesulfonic acid, and its chemical structure is described as follows:
The core of this compound is a pyridine ring, and pyridine is a nitrogen-containing hexamembered heterocycle. Five carbon atoms in the ring are connected to one nitrogen atom by a conjugated double bond, showing a planar structure that endows pyridine with a certain aromaticity. At position 4 of the pyridine ring, an ethyl group is connected by a carbon-carbon single bond. Ethyl is a group composed of two saturated carbon atoms connected by a single bond. The carbon atom at the end of the ethyl group is connected to the sulfonic acid group (-SO-H), and the sulfur atom in the sulfonic acid group is connected to three oxygen atoms, one of which is connected to the sulfur by a double bond, and the other two oxygen atoms each have a negative charge, forming an -OH structure with hydrogen. This structure makes 2- (4-pyridyl) ethanesulfonic acid have a certain acidity. In chemical reactions and related applications, the pyridine ring, ethyl group and sulfonic acid group each play a unique role, and their structural characteristics determine the physical, chemical properties and related uses of the compound.
What are the main uses of 2- (4-Pyridyl) Ethanesulfonic Acid?
2-%284-Pyridyl%29Ethanesulfonic Acid, that is, 2- (4-pyridyl) ethanesulfonic acid, this substance has a wide range of uses.
In the field of pharmaceutical and chemical industry, it can be used as an important intermediate. The special structure of geinpyridyl and sulfonic acid groups endows it with specific chemical activities and pharmacological properties. Based on this, it can undergo a series of chemical reactions to construct complex drug molecules with specific physiological activities, or to develop new drugs for the treatment of specific diseases.
In the field of materials science, it can participate in the surface modification of materials. With the strong hydrophilicity and reactivity of sulfonic acid groups, the surface properties of materials can be optimized, such as improving the hydrophilicity and stain resistance of materials, or enhancing the compatibility with other substances, which plays a significant role in the preparation of high-performance composites and biomedical materials.
In the field of chemical analysis, it also has important functions. Because of its specific acid-base properties and structure, it can be used as a buffer to maintain a stable pH value of the solution, ensure that the chemical reaction is carried out at a suitable pH during the analysis process, and improve the accuracy of the analysis results. It can also be used as a ligand to complex with metal ions, and is used in the detection and separation of metal ions, providing a powerful tool for chemical analysis.
In biochemical research, 2- (4-pyridyl) ethanesulfonic acid can be used for the study of biological macromolecules such as proteins and nucleic acids. Because its specific structure can interact with biological macromolecules, or affect the structure and function of biological macromolecules, it is helpful to explore the mechanism of action of biological macromolecules and promote the development of the field of biochemistry.
What are the physical properties of 2- (4-Pyridyl) Ethanesulfonic Acid?
2-%284-Pyridyl%29Ethanesulfonic Acid is 2- (4-pyridyl) ethanesulfonic acid, which is related to its physical properties.
Its appearance is often white to off-white crystalline powder, which is easy to identify. In terms of solubility, it is soluble in water. This property makes it beneficial in the reaction or application of many aqueous phase systems. It can be evenly dispersed and is conducive to participating in various chemical processes.
From the perspective of stability, it is quite stable under conventional environmental conditions. However, under extreme conditions such as strong acid, strong base or high temperature, chemical changes may occur, resulting in changes in structure and properties. Its melting point is also an important physical property, and a specific value can be obtained by measurement. This melting point information is of great significance in the purity identification, separation and purification of substances.
In addition, 2 - (4 - pyridyl) ethanesulfonic acid has a certain acidity. Because it contains sulfonic acid groups, it can release protons under appropriate conditions. This acidic property can play a key role in some acid-base catalyzed reactions, which can affect the reaction rate and direction. It also has a certain dissolution behavior in organic solvents, and different organic solvents have different solubility. This difference is of guiding value in the extraction, crystallization and other operations of substances. In short, various physical properties are interrelated and jointly determine the application of 2 - (4 - pyridyl) ethanesulfonic acid in chemistry, biochemistry and other fields.
What are the synthesis methods of 2- (4-Pyridyl) Ethanesulfonic Acid?
To prepare 2 - (4 - pyridyl) ethanesulfonic acid, it can be obtained by the addition reaction of 4 - vinylpyridine with sodium bisulfite. The method is as follows: In a reaction bottle equipped with a stirrer, a thermometer, and a reflux condenser, add an appropriate amount of water, and then put in 4 - vinylpyridine and sodium bisulfite in turn. The ratio of the two substances should be 1:1.2. Turn on stirring, heat up to 80 - 90 ° C, and the reaction lasts for 4 - 6 hours. During the reaction, pay close attention to the temperature of the system and the reaction process. After the reaction is completed, the reaction solution is cooled to room temperature, and distilled under reduced pressure to remove water, and the crude product can be obtained. The crude product is recrystallized by ethanol to obtain pure 2- (4-pyridyl) ethanesulfonic acid.
Another method is to use 4-pyridyl ethanol as the starting material and react with chlorosulfonic acid. Under the cooling of an ice bath, 4-pyridyl ethanol is slowly dropped into the reaction vessel containing chlorosulfonic acid, and the ratio of the two substances is about 1:1.5. The dropwise process must be slow to prevent the reaction from being too violent. After dripping, remove the ice bath and stir at room temperature for 2-3 hours. Then, the reaction mixture is poured into ice water, neutralized with sodium hydroxide solution to neutral, and then extracted, dried, and distilled under reduced pressure to obtain the target product. However, this process requires attention to the strong corrosiveness of chlorosulfonic acid, and the operation must be cautious.
What is the price range of 2- (4-Pyridyl) Ethanesulfonic Acid in the market?
In today's world, it is not easy to know the price range of 2- (4-pyridyl) ethanesulfonic acid in the market. The price of this chemical often changes due to multiple reasons.
First, the source of the goods is different, and the price is different. If it is produced in a famous factory with excellent craftsmanship and excellent quality, the price will be high; if it is out of an ordinary workshop, although it can be used, the price may be slightly lower.
Second, the amount is also the main reason. If the buyer asks for a large amount, the merchant may give a discount in order to promote the sale, and the unit price will drop; if only a little is needed, in order to meet the small use, the price may be high.
Third, the supply and demand of the city will determine the price. If there are many customers, but the production is insufficient, the price will rise; if the supply exceeds the demand, the merchant will sell the goods, or reduce the price.
However, according to past transactions and market observations, the price of 2- (4-pyridyl) ethanesulfonic acid is between a few and ten yuan per gram. This is only an approximate number, and it is not an exact value. To know the true price, you must consult the chemical supplier in detail and compare the quotation. And the market situation is changing rapidly. When inquiring about the price, you should also pay attention to the current market situation to avoid mistakes.