What is the chemical structure of 2,5-dichloro-4- {3-methyl-5-oxo-4- [ (E) - (4-sulfophenyl) diazo] -4,5-dihydro-1H-pyrazole-1-yl} benzenesulfonic acid?
The chemical structure of 2% 2C5-dihydro-4- {3-methyl-5-oxo-4- [ (E) - (4-pyridyl) diazo] -4,5-dihydro-1H-pyrazole-1-yl} pyridinecarboxylic acid can be understood as follows.
The core structure of this compound is pyridinecarboxylic acid, and there are hydrogen atoms at the 2nd and 5th positions of the pyridine ring in a dihydrogen state. At the 4th position of the pyridine ring, a complex substituent is connected. The substituent is initially a nitrogen-containing five-membered heterocyclic ring, namely a 1H-pyrazole ring. At the 3rd position of the pyrazole ring, there is a methyl group, and at the 5th position, the oxygen atom constitutes a carbonyl (5-oxo). At the 4th position of the pyrazole ring, there is a diazo group connected, and this diazo group is connected to the 4-pyridyl group of the (E) configuration. The entire pyrazole ring is also in the 4,5-dihydro state, and is connected to the 4th position of the pyridine ring at the 1st position. In such a structure, each atom and group are connected to each other by specific chemical bonds to form a specific spatial arrangement, which endows the compound with specific chemical and physical properties, and may have specific uses and reactivity in fields such as organic synthesis and medicinal chemistry.
What are the main uses of 2,5-dichloro-4- {3-methyl-5-oxo-4- [ (E) - (4-sulfophenyl) diazo] -4,5-dihydro-1H-pyrazole-1-yl} benzenesulfonic acid?
2% 2C5-difluoro-4- {3-methyl-5-oxo-4- [ (E) - (4-pyridyl) diazo] -4,5-dihydro-1H-pyrazole-1-yl} pyridinecarboxylic acid, this substance has important uses in many fields.
In the field of medicinal chemistry, due to its unique chemical structure, it can be used as a lead compound for drug development. Studies have shown that pyridine and pyrazole structural units have important contributions to biological activity. Through their modification and optimization, new antibacterial, anti-inflammatory and anti-tumor drugs may be developed. For example, some structural drugs containing pyridine and pyrazole can effectively inhibit the proliferation of specific cancer cells.
In the field of materials science, this substance may be used to prepare functional materials. Because it contains diazo groups and fluorine atoms, the photoresponsiveness of diazo groups makes the material have photochromic properties and can be used in optical information storage materials; the introduction of fluorine atoms can improve the thermal stability, chemical stability and surface properties of materials, or be used in the preparation of high-performance coatings and film materials.
In the field of agriculture, this substance may have potential agricultural value. Some structural compounds containing pyridine and pyrazole exhibit insecticidal, bactericidal and herbicidal activities. By studying their structure-activity relationship, high-efficiency, low-toxicity and environmentally friendly pesticides may be developed, providing new options for agricultural pest control.
What are the precautions for using 2,5-dichloro-4- {3-methyl-5-oxo-4- [ (E) - (4-sulfophenyl) diazo] -4,5-dihydro-1H-pyrazole-1-yl} benzenesulfonic acid?
2% 2C5-difluoro-4- {3-methyl-5-oxo-4- [ (E) - (4-cyanobenzyl) diazo] -4,5-dihydro-1H-pyrazole-1-yl} benzonitrile acid When using, there are several ends to pay attention to.
First, this substance has a specific chemical activity. When operating, strictly follow safety procedures and apply appropriate protection measures, such as protective clothing, goggles and gloves, to prevent it from coming into contact with the skin and eyes, or accidentally inhaling or ingesting, because it may be harmful to human health.
Second, in view of the characteristics of its chemical structure, there are also requirements for storage conditions. It needs to be stored in a cool, dry and well-ventilated place, away from fire and heat sources, to avoid co-storage with oxidants, acids, alkalis and other substances, in order to prevent chemical reactions, deterioration or safety accidents.
Furthermore, during use, the reaction conditions need to be precisely controlled. Factors such as temperature, pH, reaction time, etc., will affect the reaction process and product formation. Make sure that the reaction is carried out under suitable conditions to achieve the expected reaction effect and product quality.
Repeat, the experimental operation should be fine and standardized. The steps of taking, weighing, transferring, etc. should be handled with the help of appropriate instruments and equipment to ensure accurate measurement, and attention should be paid to avoid spillage during operation. If there is any spillage, it should be properly cleaned and disposed of immediately in accordance with regulations.
At the end of the day, after the use of this material, its waste should also be disposed of in accordance with regulations and should not be discarded at will to avoid pollution to the environment. Appropriate methods must be selected for disposal in accordance with relevant environmental protection regulations to reduce its harm to the ecological environment.
What are the synthesis methods of 2,5-dichloro-4- {3-methyl-5-oxo-4- [ (E) - (4-sulfophenyl) diazo] -4,5-dihydro-1H-pyrazole-1-yl} benzenesulfonic acid?
The synthesis of 2% 2C5-dioxo-4- {3-methyl-5-oxo-4- [ (E) - (4-cyanobenzyl) diazo] -4,5-dihydro-1H-pyrazole-1-yl} benzonitrile acid is a key investigation in organic synthetic chemistry. The methods are different, and the common methods are the selection and preparation of starting materials. Select a suitable substrate and cause the target product through multi-step reactions.
One method starts with a benzene derivative containing a specific substituent, and first introduces methyl, cyano and other groups through a substitution reaction. In this process, suitable reaction conditions and catalysts are selected, such as halogenated benzene and methylation reagents, under the catalysis of alkali, nucleophilic substitution is performed to obtain methyl-containing benzene derivatives.
Then, through oxidation reaction, the carbonyl structure is constructed. This step requires careful control of the reaction conditions to prevent excessive oxidation. Then diazo groups are introduced by diazotization reaction. The diazotization reaction requires strict reaction conditions, such as temperature and pH value.
Another synthesis method starts with the construction of pyrazole rings. After the condensation reaction of nitrogenous compounds and carbonyl compounds, pyrazole rings are first formed, and then gradually modified to introduce benzene rings and other substituents. In this process, the order and conditions of each step of the reaction need to be refined to improve the yield and selectivity of the reaction.
The key to synthesis lies in the precise control and optimization of each step of the reaction. From the choice of reaction reagents, the choice of catalysts, to the adjustment of reaction temperature and time, the purity and yield of the final product are all related. After each step of the reaction, separation and purification are often required to remove impurities and ensure the smooth progress of the reaction. Synthesis of 2% 2C5-dioxo-4- {3-methyl-5-oxo-4- [ (E) - (4-cyanobenzyl) diazo] -4,5-dihydro-1H-pyrazole-1-yl} benzonitrile acid requires deep knowledge and rich experience in the field of organic synthesis. After repeated tests and optimization, an efficient and feasible synthesis method can be obtained.
What are the physicochemical properties of 2,5-dichloro-4- {3-methyl-5-oxo-4- [ (E) - (4-sulfophenyl) diazo] -4,5-dihydro-1H-pyrazole-1-yl} benzenesulfonic acid?
2% 2C5-difluoro-4- {3-methyl-5-oxo-4- [ (E) - (4-cyanobenzyl) diazo] -4,5-dihydro-1H-pyrazole-1-yl} benzonitrile acid is a complex organic compound. Its unique physical and chemical properties are related to many fields of organic synthesis and chemistry research.
Let's talk about the physical properties first. Under normal conditions, or in a solid state, due to the structure of polyaromatic rings and polar groups, the intermolecular force is quite strong, resulting in a relatively high melting point. And its solubility depends on the polar organic solvents, such as dimethyl sulfoxide (DMSO), N, N-dimethylformamide (DMF), or has a certain solubility. The polar groups in the guain molecule can form hydrogen bonds or other intermolecular forces with polar solvents; in non-polar solvents, such as n-hexane and benzene, the solubility may be extremely low, because the non-polar part is difficult to interact with non-polar solvents.
Let's talk about chemical properties. The cyano group (-CN) in this compound has high reactivity and can participate in reactions such as nucleophilic addition and hydrolysis. The diazo group is also very active, which is a typical feature of diazo compounds. Reactions such as diazo transfer and coupling can occur, and it is often used as a key intermediate in organic synthesis. Furthermore, the structure of the pyrazole ring endows it with certain acid-base properties, and the nitrogen atom of the pyrazole ring can accept protons, showing weak alkalinity and protonation under acidic conditions; at the same time, hydrogen atoms at certain positions on the pyrazole ring can be replaced by other groups under appropriate conditions, and electrophilic substitution reactions occur. In addition, the introduction of multiple fluorine atoms in the molecule not only affects its physical properties, such as improving fat solubility, but also enhances molecular stability in chemical reactions. Due to its high C-F bond energy, it will also affect the electron cloud distribution of neighboring groups, altering their reactivity and selectivity.
![2,5-Dichloro-4-{3-Methyl-5-Oxo-4-[(E)-(4-Sulfophenyl)Diazenyl]-4,5-Dihydro-1H-Pyrazol-1-Yl}Benzenesulfonic Acid](https://alchemist-1317689233.cos.ap-nanjing.myqcloud.com/fc6509f5-a84d-4824-8744-1c4935d3edf8/images/product_inner1.jpg)
