What are the main uses of 2-Amino-5-Naphthalenesulfonic Acid?
2-Amino-5-naphthalenesulfonic acid, this is an organic compound. It has a wide range of uses and plays an important role in the dye industry.
The cover provides a key raw material for dye synthesis due to its unique structure, containing amino and sulfonic acid groups, which endows it with many properties. Through a series of chemical reactions, it can be cleverly combined with other compounds to create colorful and excellent dyes. The preparation of many types of dyes such as acid dyes and direct dyes often relies on this substance.
In the field of medicine, it also has certain applications. Due to its specific chemical properties, it may participate in the synthesis of some pharmaceutical intermediates. Drug intermediates are key links in drug synthesis. After further reaction and modification, they can be converted into drugs with specific pharmacological activities.
In addition, in the field of organic synthesis, 2-amino-5-naphthalenesulfonic acid is an important raw material for organic synthesis, which can be used to synthesize many organic compounds with special structures and functions. Its sulfonic acid groups and amino groups can participate in a variety of reactions, such as substitution reactions, condensation reactions, etc., providing organic synthesis chemists with rich strategies and paths to construct complex and novel organic molecular structures to meet the needs of different fields for special organic compounds.
What are the physical properties of 2-Amino-5-Naphthalenesulfonic Acid?
2-Amino-5-naphthalenesulfonic acid, its shape is white to light gray powder, slightly soluble in cold water, easily soluble in hot water. When its aqueous solution encounters ferric chloride test solution, it is dark purple. The melting point is about 300 ° C, and toxic gases are liberated when heated. The substance is relatively stable in acidic media, and may react accordingly under alkaline conditions. Because its molecule contains amino and sulfonic acid groups, it has a certain acid-base amphoteric, and can interact with acids and bases respectively. In organic solvents, its solubility is relatively limited, and it mostly exhibits hydrophilicity. This substance is widely used in chemical fields such as dyes and medicine, and is an important intermediate in organic synthesis.
What are the chemical properties of 2-Amino-5-Naphthalenesulfonic Acid?
2-Amino-5-naphthalenesulfonic acid is a class of organic compounds. Its chemical properties are unique, so let me tell you in detail.
This compound is acidic, due to the sulfonic acid group (-SO-H). The sulfonic acid group can dissociate hydrogen ions in water, thus exhibiting acidic properties, and can neutralize with bases to form corresponding salts. If reacted with sodium hydroxide, hydrogen ions in the sulfonic acid group combine with hydroxyl ions to form water, and then form 2-amino-5-naphthalenesulfonic acid sodium.
The amino group of 2-amino-5-naphthalenesulfonic acid (-NH _ 2) has a certain alkalinity. Although the alkalinity of amino groups is weaker than that of common inorganic bases, they can react with acids under certain conditions. For example, when interacting with hydrochloric acid, amino nitrogen atoms can bind hydrogen ions to form a positively charged ammonium salt structure.
There is a conjugate system in its molecules, and the electron cloud between the naphthalene ring and the amino group and the sulfonic acid group affects each other. This conjugate structure has a significant effect on the stability and spectral properties of the compound. Due to the conjugate effect, the compound is relatively stable, and there is a specific absorption peak in the ultraviolet-visible spectrum, which is conducive to its qualitative and quantitative analysis.
2-amino-5-naphthalenesulfonic acid can also undergo substitution reactions. The amino group and the sulfonic acid group are both activating groups, which can increase the electron cloud density on the naphthalene ring and make the naphthalene ring more susceptible to attack by electrophilic reagents. Under appropriate conditions, electrophilic reagents can replace the hydrogen atoms on the naphthalene ring to form various substituted derivatives.
In terms of redox reaction, 2-amino-5-naphthalenesulfonic acid also has certain characteristics. The structure of the naphthalene ring connected to the amino group and the sulfonic acid group may undergo oxidation reaction under the action of a specific oxidant, resulting in the change of the structure of the naphthalene ring or the transformation of functional groups; in the case of strong reducing agents, reduction reactions may also occur, such as hydrogenation and reduction of the naphthalene ring. The chemical properties of 2-amino-5-naphthalenesulfonic acid are rich and diverse, and it has important application value in many fields such as organic synthesis, dye preparation, and drug development.
What is the production method of 2-Amino-5-Naphthalenesulfonic Acid?
2-Amino-5-naphthalenesulfonic acid, formerly known as turnionic acid, was prepared by the following steps in the past.
First, naphthalene was used as the starting material and was sulfonated. In a specific reactor, naphthalene was injected and sulfuric acid was used as the sulfonating agent, and the temperature was controlled at a certain range, such as 160-165 ° C. After a few hours, the sulfonation of naphthalene was reacted into 1-naphthalenesulfonic acid. In this reaction, the concentration of sulfuric acid, the reaction temperature and time are all key factors, and a slight difference in the pool affects the purity and yield of the product.
The reaction of nitrification of 1-naphthalenesulfonic acid under the catalysis of mercury salt Usually, mixed acid (a mixture of nitric acid and sulfuric acid) is used as a nitrifying agent. At an appropriate low temperature, such as 0-5 ° C, the mixed acid is slowly added dropwise to obtain 1-nitro-2-naphthalenesulfonic acid. The dosage of mercury salt, the ratio of mixed acid and the speed of dropwise addition all need to be precisely controlled, otherwise it is prone to side reactions and the product is complicated and difficult to purify.
Next, 1-nitro-2-naphthalenesulfonic acid is reduced. Iron powder and hydrochloric acid are often used as a reduction system, heated and refluxed to convert the nitro group into an amino group, and then 2-amino-5-naphthalenesulfonic acid is obtained. The fineness of iron powder, the concentration of hydrochloric acid, and the temperature and time of the reaction have a great influence on the reduction effect.
Finally, the product is separated and purified. First, the pH value of the reaction solution is adjusted by neutralization, so that the product precipitates and precipitates, and then filtration, washing, recrystallization and other means are used to improve the purity of the product to meet the standards of industrial applications or other uses. Each step of the reaction is related to the quality and output of the product. Fine operation is required to obtain the ideal 2-amino-5-naphthalenesulfonic acid.
What is the price range of 2-Amino-5-Naphthalenesulfonic Acid in the market?
In today's market, the price of 2-amino-5-naphthalenesulfonic acid often varies due to quality, supply and demand. In the past, "Tiangong Kaiwu" was written in the Ming Dynasty, and the price of this product was not stated at that time, because the chemical process at that time was not in this state.
In today's world, 2-amino-5-naphthalenesulfonic acid in the city, if it is an ordinary industrial grade, the price per kilogram may be in the tens of yuan. However, if its purity is quite good, it is suitable for high-end fields such as fine chemicals and pharmaceutical research and development, and the price is high. For high purity, it may reach hundreds of yuan per kilogram.
In addition, the supply and demand situation has a huge impact on the price. If there are many people in the market, but there are few products, the price will rise; on the contrary, if there is excess capacity and weak demand, the price will also fall. And in different places, due to different logistics, taxation, etc., the price is also different. Basically speaking, in prosperous commercial ports, due to convenient circulation and fierce competition, the price may be relatively easy; in remote places, due to difficult transportation, the price may be slightly higher. Therefore, if you want to know the exact price, you should carefully study the market conditions and visit merchants and business people before you can get it.