What is the main use of this '2-anthracenesulfonic acid, 1-amino-9,10-dihydro-9,10-dioxo-4- (2,4,6-trimethylphenyl) amino-, monosodium salt '?
"This '2-aminobenzoic acid, 1-hydroxy-9,10-dioxo-9,10-dioxo-4- (2,4,6-trimethylphenyl) hydroxy-monosodium salt ', its main use is as an intermediate for pharmaceutical synthesis. Among the uses of many things involved in" Tiangong Kaiwu ", although there is no direct description of this thing, it can be deduced from the ancient pharmaceutical and technological ideas, and it can probably be considered from the ideas of drug processing and chemical synthesis.
In ancient pharmacy, plants, wood, gold and stone were often used as raw materials, and they were processed and compatible to make medicines. If this compound is involved in medicine, it may be a key starting material for the synthesis of specific medicinal components. The amino groups, hydroxyl groups and other functional groups it contains can participate in the construction of complex drug molecules by borrowing the "medicinal properties" interaction principle understood by ancient processes.
From the perspective of chemical synthesis, although "Tiangong Kaiwu" does not describe the synthesis of such complex compounds in detail, its records of the transformation of various substances, such as metal smelting, ceramic firing, etc., contain the idea of reaction and transformation between substances. The preparation of this compound may be analogous to the idea of controlling raw material processing and reaction conditions in ancient processes. The form of monosodium salt, or in order to adjust its solubility and stability in a specific environment, is similar to the adjustment of the form and properties of drugs in ancient medicine to achieve better medicinal effects. In general, this substance is mainly used as an important intermediate in the synthesis of more complex and effective drugs in the field of medicine. "
What are the chemical characteristics of '2-anthracenesulfonic acid, 1-amino-9,10-dihydro-9,10-dioxo-4- (2,4,6-trimethylphenyl) amino-, monosodium salt '?
"2-Naphthalenesulfonic acid, 1-amino-9,10-dihydro-9,10-dioxo-4- (2,4,6-trimethylphenyl) amino-, monosodium salt" This substance has acid-base characteristics. The naphthalenesulfonic acid structure has a sulfonic acid group, which can ionize hydrogen ions in water, is acidic, and can react with bases to form salts. This monosodium salt is the result of its reaction with bases.
From the perspective of electronic effects, the naphthalene ring is a large conjugated system, which will affect the electron cloud distribution and activity of groups such as sulfonic acid groups and amino groups. The structures of amino groups and dioxides give molecules a certain polarity, which affects their solubility and reactivity.
Due to the presence of multiple aromatic rings and conjugated structures, this substance has certain stability and can resist some common chemical reactions. However, amino groups are easily oxidized, and under the action of strong oxidants, amino groups may be oxidized to other groups such as nitro groups.
Its conjugated structure makes it absorb specific wavelengths of light, or has certain optical properties, which can be used in photochemical related fields. And contains multiple substituents, different substituents interact, or can participate in a variety of organic reactions, such as nucleophilic substitution, electrophilic substitution, etc. It can be used as a key intermediate in organic synthesis to construct more complex organic molecular structures.
'2-Anthracenesulfonic acid, 1-amino-9,10-dihydro-9,10-dioxo-4- (2,4,6-trimethylphenyl) amino-, monosodium salt 'is used in which industries
"2-Naphthalenesulfonic acid, 1-amino-9,10-dioxy-9,10-dihydro-4- (2,4,6-trimethylphenyl) amino-, monosodium salt" This product is used in many industries. Although it is not directly recorded in Tiangong Kaiwu, from an ancient perspective, combined with the description of various process materials in the book, it can be used in the industry.
In the dyeing and weaving industry, the preparation of many dyes requires fine chemicals as raw materials or intermediates. This compound contains groups such as naphthalenesulfonic acid and amino group, or can be chemically converted to produce dyes with bright color and good fastness. It is used for fabric dyeing to make fabrics rich and lasting. Just like the emphasis on various dyeing processes in "Tiangong Kaiwu", the pursuit of exquisite and lasting color.
In the papermaking industry, chemicals are often used to improve the performance of paper. The sodium salt form of this compound can be used as a dispersant, retention aid, etc. For example, the dispersant can make the fibers evenly dispersed, avoid agglomeration, and improve the uniformity of the paper; the retention aid helps the fibers and fillers remain in the paper, improving the strength of the paper and other properties, just like the description of the paper quality process in the papermaking chapter of "Tiangong Kaiwu".
In the field of pharmaceutical synthesis, the complex structure of this compound contains a variety of active groups, or is a key intermediate for the synthesis of specific drugs. By modifying its structure through chemical reactions, drugs with specific pharmacological activities can be obtained, which is in line with the spirit of ancient medicine's exploration of natural and synthetic drugs. Although "Tiangong Kaiwu" does not involve the details of medical chemistry, the concept of exploration and creation is the same.
In addition, in the coating industry, it can be used as a coating additive to improve the film formation, adhesion, and weather resistance of coatings. Make the coating better protect the surface of the coated object, just like the development and application of various protective coatings in ancient times, so as to achieve the purpose of long-term protection of objects.
What is the production process of '2-anthracenesulfonic acid, 1-amino-9,10-dihydro-9,10-dioxo-4- (2,4,6-trimethylphenyl) amino-, monosodium salt '?
The production process of "2-bromobenzoic acid, 1-amino-9,10-dihydro-9,10-dioxo-4- (2,4,6-trimethylphenyl) amino-mono-potassium salt", according to the ancient classical style of "Tiangong Kaiwu", is described as follows:
The husband wants to make this "2-bromobenzoic acid, 1-amino-9,10-dihydro-9,10-dioxo-4- (2,4,6-trimethylphenyl) amino-mono-potassium salt", according to a certain order, using a specific method.
First, choose a pure starting material. In the preparation of "2-bromobenzoic acid", when bromine and benzoic acid are used as the basis, choose the appropriate reaction conditions. The amount of bromine, the temperature and pressure of the reaction need to be carefully controlled. Bromine, an active halogen element, reacts with benzoic acid in a mild environment. You can first place benzoic acid in a reactor, slowly add bromine, and at the same time, add a catalyst to promote the reaction speed, so that bromine can accurately replace the hydrogen atom at a specific position of benzoic acid to obtain pure "2-bromobenzoic acid".
times, it is the synthesis of "1-amino-9,10-dihydro-9,10-dioxo-4- (2,4,6-trimethylphenyl) amino-". Using related organic compounds as raw materials, it is formed through several steps of reaction. First, a compound containing an amino group reacts with another substance with a specific structure in an alkaline environment. The degree of alkalinity is related to the direction of the reaction. If the base is strong, it is easy to cause side reactions, and if the base is weak, the reaction is slow. When finding an appropriate degree, the two can be condensed smoothly, and then through oxidation and other steps, the structure of "9,10-dioxo" is formed. And when introducing "4- (2,4,6-trimethylphenyl) amino-", a suitable reaction path should be selected so that the phenyl group is accurately connected to the target position. After
, the above-obtained product is mixed with the potassium salt solution. The type and concentration of potassium salts also need to be carefully determined. The two are mixed, and after stirring and reacting for a certain period of time, potassium ions replace specific hydrogen atoms to form this "single potassium salt". Finally, after separation and purification, such as filtration, crystallization, washing and other steps, pure "2-bromobenzoic acid, 1-amino-9,10-dihydro-9,10-dioxo-4- (2,4,6-trimethylphenyl) amino-, monopotassium salt" are obtained. The whole process, the amount of material, the reaction environment, and the order of steps cannot be slightly different before this delicate product can be obtained.
What are the environmental effects of '2-anthracenesulfonic acid, 1-amino-9,10-dihydro-9,10-dioxo-4- (2,4,6-trimethylphenyl) amino-, monosodium salt '?
"2-Cyano-1-amino-9,10-dihydro-9,10-dioxo-4- (2,4,6-trimethylphenylamino) benzoic acid, mono-potassium salt" The impact of this substance on the environment is quite complex.
Looking at its chemical structure, cyanide-containing compounds, if released in the natural environment, may be significantly toxic to water and soil organisms. Cyanide can inhibit the activity of many enzymes in organisms, especially cytochrome oxidase, hinder biological respiration, and cause biological cells to be unable to use oxygen effectively, thus posing a threat to the survival and reproduction of aquatic organisms such as fish, plankton, and soil microbial communities.
It contains amino and dioxo structures, and can participate in various chemical reactions in the environment. Amino groups have certain hydrophilicity and reactivity, or affect the distribution of compounds between soil and water, and or react with other substances in the environment. The dioxo structure makes the molecule have a certain polarity, which affects its migration and diffusion characteristics in the environmental medium.
Furthermore, the existence of trimethylphenyl groups, due to the stability and hydrophobicity of the benzene ring, or makes the compound difficult to be degraded by microorganisms, and persists in the environment. The substitution of methyl groups on the benzene ring changes the distribution of the electron cloud of the benzene ring, which affects the chemical reactivity and bioavailability of the compound.
As for the single potassium salt form, although potassium ions are common ions and generally have low toxicity in the environment, they may change the ionic strength and acidity and alkalinity of compounds in soil and water, and indirectly affect the chemical balance and biological community structure of the surrounding environment. For example, after changing the pH of the soil, it affects the nutrient availability in the soil and the absorption of nutrients by plant roots.