As a leading 2-Azabicyclo[3.1.0]Hexane-3-Carboxamide, (1S,3S,5S)-,Monomethanesulfonate supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
2-Azabicyclo [3.1.0] Hexane-3-Carboxamide, (1S, 3S, 5S) -, what is the chemical structure of Monomethanesulfonate
This is a difficult problem in organic chemistry, which needs to be solved with professional knowledge and prudence. 2 - Azabicyclo [3.1.0] Hexane - 3 - Carboxamide, (1S, 3S, 5S) -, Monomethanesulfonate, the name shows that the structure is complex.
Preface "2 - Azabicyclo [3.1.0] Hexane", this is a double ring structure, containing nitrogen atoms, and the number and connection of the rings are determined. "- 3 - Carboxamide" indicates that there is a formamide group at the 3rd position. And " (1S, 3S, 5S) " defines the configuration of the chiral center.
As for "Monomethanesulfonate", it refers to the salt formed with methanesulfonic acid.
Its chemical structure can be deduced as follows: Bicyclic [3.1.0] hexane is used as the parent nucleus, nitrogen-containing atoms are introduced at 2 positions, formamide groups are connected at 3 positions, and the three-dimensional configuration at 1, 3, and 5 positions is S-type. The methanesulfonate ion is connected to the parent structure by ionic bonds.
In this way, the chemical structure of this compound can be roughly obtained. Although the process is complicated, the laws of organic chemistry can also give insight into the delicacy of its structure.
2-Azabicyclo [3.1.0] Hexane-3-Carboxamide, (1S, 3S, 5S) -, What are the physical properties of Monomethanesulfonate
(1S, 3S, 5S) -2-azabicyclo [3.1.0] hexane-3-formamide monomethanesulfonate, which has many physical properties. Its appearance may be white to off-white crystalline powder, which is a common appearance of many organic salts. Due to the orderly arrangement of molecules and light scattering properties, it appears so.
The melting point is quite critical in the identification of organic compounds. The melting point of (1S, 3S, 5S) -2-azabicyclo [3.1.0] hexane-3-formamide monomethanesulfonate may be in a specific range, but the exact value needs to be determined by precise experiments. Due to factors such as subtle structural differences and impurities, the melting point fluctuates slightly.
Solubility is also an important property. It may have a certain solubility in water, and the methanesulfonic acid group can interact with water molecules to form hydrogen bonds, etc., to promote dissolution; in common organic solvents such as ethanol and acetone, the solubility may vary according to molecular polarity matching and solvation, and polar organic solvents may have better solubility.
Stability is related to its storage and application. In a dry environment at room temperature, the structure may be relatively stable, but when exposed to high temperature, high humidity or specific chemicals, or chemical reactions cause structural changes, storage requires appropriate conditions. These are all possible physical properties of (1S, 3S, 5S) -2-azabicyclo [3.1.0] hexane-3-formamide monomethanesulfonate, which need to be verified by detailed experiments.
2-Azabicyclo [3.1.0] Hexane-3-Carboxamide, (1S, 3S, 5S) -, What are the common uses of Monomethanesulfonate
2-Azabicyclic [3.1.0] hexane-3-formamide, (1S, 3S, 5S) -, monomethanesulfonate, what are the common uses of this compound? Let me tell you.
This compound may have important uses in the field of medicinal chemistry. In drug development, its unique structure gives it specific biological activities. For example, in some studies targeting specific disease targets, it may be used as a key active ingredient. Because of its special dicyclic structure and methanesulfonate modification, it can interact with specific biological macromolecules such as proteins and enzymes in organisms.
In the exploration of drugs for some neurological diseases, compounds with such structures may regulate the transmission of neurotransmitters or affect the function of related receptors, thus providing potential directions for the treatment of diseases such as Parkinson's disease and Alzheimer's disease. In the field of anti-tumor drug research, it may be able to interfere with the proliferation signaling pathway of tumor cells and inhibit the growth and spread of tumor cells.
Furthermore, it can be used as an important structural template in the study of structure-activity relationships in pharmaceutical chemistry. By modifying and modifying different check points on its structure, the effect of structural changes on activity can be systematically studied, and then new drug molecules with stronger activity, higher selectivity and fewer side effects can be optimized.
At the same time, in the field of organic synthetic chemistry, it can also be used as an important intermediate. With its unique functional groups, it can participate in a variety of organic reactions and be used to construct more complex organic compound structures, providing an important material basis for the development of organic synthetic chemistry.
What are the synthesis methods of 2-Azabicyclo [3.1.0] Hexane-3-Carboxamide, (1S, 3S, 5S) -, Monomethanesulfonate
The synthesis of (1S, 3S, 5S) -2-azabicyclo [3.1.0] hexane-3-formamide monomethanesulfonate is an important research direction in the field of organic synthesis. This synthesis requires delicate design and steps.
The starting material is quite critical, and the one with suitable activity and structure should be selected. Nitrogen-containing heterocycles and carboxyl groups or their derivatives can be found to lay the foundation for the construction of the core structure of the target molecule.
The cyclization reaction is a key step. Cyclization reactions, such as intramolecular nucleophilic substitution, can be used. In this process, the reaction conditions such as temperature, solvent, catalyst, etc. need to be precisely regulated. Taking nucleophilic substitution in molecules as an example, suitable bases are used as catalysts, and specific organic solvents create a suitable reaction environment. Precise temperature control makes the reaction move towards cyclization efficiently, and the 2-azabicyclic [3.1.0] hexane structure is successfully constructed. The conversion of carboxyl groups to formamide groups is also a challenge. The carboxyl group can be converted to acid chloride first by the acid chloride intermediate method, and then reacted with ammonia or amines to obtain formamide groups. Among them, the preparation of acid chloride needs to pay attention to the reactivity and stability to prevent side reactions.
As for the formation of monomethanesulfonate, (1S, 3S, 5S) -2 -azabicyclo [3.1.0] hexane-3 -formamide can be reacted with methanesulfonic acid in a suitable ratio under suitable conditions. It is necessary to pay attention to the effect of reaction conditions on salt purity and crystal form.
After each step of reaction, it is necessary to properly separate and purify, and obtain high-purity intermediates and target products by means of column chromatography and recrystallization to ensure the smooth progress of the synthesis route, and finally obtain high-purity (1S, 3S, 5S) -2 -azabicyclo [3.1.0] hexane-3 -formamide monomethanesulfonate.
2-Azabicyclo [3.1.0] Hexane-3-Carboxamide, (1S, 3S, 5S) -, Monomethanesulfonate presence of toxicity
I don't know what you said about 2 - Azabicyclo [3.1.0] Hexane - 3 - Carboxamide, (1S, 3S, 5S) -, Monomethanesulfonate. To determine whether it is toxic or not, it is necessary to carefully investigate the chemical properties, structure and past studies of this substance.
If this substance is a newly created compound, the ancients have not been involved, and it is difficult to judge by ancient theory. However, according to today's chemical common sense, the toxicity of many organic compounds may be due to the specific functional groups in the structure. Such as groups containing heavy metals, parts with strong oxidizing or reducing properties, or those that are easy to react with key molecules in organisms, are often toxic.
But it is difficult to determine its toxicity only according to the name you provided. It is necessary to use modern chemical analysis methods, such as experimental testing of its impact on biological cells, to see if it causes cell lesions and death; or in animal experiments, to observe its changes in animal physiology and behavior. Only in this way can we obtain conclusive proof of the toxicity of this substance, rather than just speculation.