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Sulfonic Acid Series Sulfamic Acid Series Guanidine Series

Sulfonic Acid Series

Sulfamic Acid Series

Guanidine Series

2-Chloroethyl 4-Toluenesulfonate

Specifications

HS Code	513403
Chemical Formula	C9H11ClO3S
Molar Mass	234.70 g/mol
Appearance	Colorless to pale yellow liquid
Density	1.28 g/cm³
Boiling Point	~130 - 132 °C at 2 mmHg
Flash Point	152 °C
Solubility In Water	Insoluble
Solubility In Organic Solvents	Soluble in common organic solvents like dichloromethane, toluene
Pungency	Has a pungent odor
Hazard Class	Corrosive, harmful if swallowed, inhaled or in contact with skin

As an accredited 2-Chloroethyl 4-Toluenesulfonate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	500g of 2 - Chloroethyl 4 - Toluenesulfonate in a well - sealed chemical - resistant bottle.
Storage	2 - Chloroethyl 4 - Toluenesulfonate should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition sources. Keep it in a tightly closed container, preferably in a corrosion - resistant cabinet due to its potential reactivity. Store separately from incompatible substances like oxidizing agents, bases and moisture - sensitive materials to prevent chemical reactions.
Shipping	2 - Chloroethyl 4 - Toluenesulfonate is shipped in accordance with strict chemical transportation regulations. It is carefully packaged to prevent leakage, typically in corrosion - resistant containers, and transported by carriers with chemical - handling expertise for safe conveyance.

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General Information

Historical Development

Wenfu 2 - Chloroethyl 4 - Toluenesulfonate this product, and there is also a reason for its rise. In the past, the chemists were diligent in exploring the field of organic synthesis. At the beginning, everyone was eager for knowledge and studied various reaction mechanisms, hoping to obtain new products to expand the boundaries of chemistry.
At that time, the public paid attention to the fusion of sulfonylation and halogenation reactions. After years of trial and error, the proportion, temperature and duration of the reactants were carefully prepared. There was a small success, but there were a lot of impurities, and the yield was not as expected.
However, Zhu Xian was not discouraged and continued to improve. Or change the solvent, or change the catalyst, and repeatedly consider. Finally, the preparation of 2 - Chloroethyl 4 - Toluenesulfonate has been perfected. Since then, this product has emerged in the fields of medicine, materials and other fields, contributing to the advancement of science and technology.

Product Overview

2-Chloroethyl-4-toluenesulfonate is an important chemical compound in chemical research. This compound has a unique structure, and its molecules are composed of chloroethyl and 4-toluenesulfonate radical groups. Its appearance is often white to white crystalline powder, with certain physical and chemical properties. In the field of chemical synthesis, it is often used as a key intermediate. With its specific chemical activity, it can participate in many organic reactions and provide a way for the synthesis of complex organic compounds. Its reactivity is derived from the synergistic effect of chlorine atoms and sulfonic acid radical groups, which makes it possible to undergo nucleophilic substitution reactions with various nucleophiles, thereby forming new carbon-carbon and carbon-heteroatomic bonds. Due to its significant role in organic synthesis, it has received extensive attention and application in both chemical research and industrial production.

Physical & Chemical Properties

2-Chloroethyl 4-Toluenesulfonate is a unique chemical product. Its physical properties are unique. At room temperature, it is a colorless to slightly yellow liquid, and it looks clear and translucent. Smell, slightly pungent odor. Its boiling point is quite high, about [X] ° C, which makes it stable in a specific temperature environment.
When it comes to chemical properties, this substance has active reactivity. Its molecular structure contains chlorine atoms and sulfonate groups. Chlorine atoms give it a tendency to nucleophilic substitution reactions, and sulfonate groups make it play a key role in many organic reactions. When encountering nucleophiles, chlorine atoms are easily replaced, and various organic compounds are derived, which are widely used in the field of organic synthesis. However, due to its liveliness, it is necessary to store it with caution to prevent accidental chemical reactions and ensure the stability of its chemical properties, so that it can be better used for scientific research and production.

Technical Specifications & Labeling

Today there is a product called 2 - Chloroethyl 4 - Toluenesulfonate. The preparation technique is related to the process specification and identification (product parameters), which is the most important thing.
If you want to make this product, you should understand the method first. According to the rules of craftsmanship, the quantity, temperature and time of each product need to be precisely controlled. The raw materials used must be suitable for their specifications, and the weighing must be accurate. This is the foundation for making good products. When reacting, the temperature and duration all affect the quality of the product.
In terms of identification, the product parameters must be detailed. Such as purity geometry and impurities, they should be marked one by one. This is not only about quality, but also for the convenience of users. In accordance with this process specification and marking, the preparation of 2-Chloroethyl 4-Toluenesulfonate can be obtained by its method, and the quality can also be guaranteed.

Preparation Method

The raw materials and production process, reaction steps and catalytic mechanism of 2-chloroethyl 4-toluenesulfonate made today are the key.
Take p-toluenesulfonyl chloride first, which is one of the important raw materials, and prepare it in an appropriate amount. Then take chloroethanol and mix the two according to a specific ratio. In the reaction vessel, add a suitable catalyst, such as an organic base, to promote the smooth progress of the reaction.
The reaction steps are as follows: Under gentle stirring of the raw material and the catalyst, gradually heat up to a certain temperature, and maintain this temperature to make the reaction fully occur. This process requires precise control of temperature and time to prevent side reactions. During the reaction, the reaction process is closely monitored, and the degree of reaction is carefully observed by modern analytical methods, such as chromatography.
The catalytic mechanism depends on the activity check point of the catalyst, which interacts with the raw material to reduce the activation energy of the reaction and accelerate the reaction rate, so that the two can be efficiently combined, and the final product is 2-chloroethyl 4-toluenesulfonate. In this way, according to this complete preparation method, the desired product can be obtained.

Chemical Reactions & Modifications

Nowadays, there is something called 2 - Chloroethyl 4 - Toluenesulfonate. In the field of chemistry, its reaction and modification are the key. Looking at its reaction, it often involves nucleophilic substitution. Halogen atoms are active and easy to be attacked by nucleophilic reagents, resulting in structural changes.
To modify this product, you can choose an adaptable method. Or introduce special groups to change its physical and chemical properties. If a reagent encounters it, the sulfonate group will change, increase its water solubility or change its reactivity.
Or adjust the conditions of the reaction, temperature, pressure and catalyst can be variables. Temperature can promote the speed of the reaction, and the best catalyst can lead the reaction to the expected direction. Through all these, the properties of 2 - Chloroethyl 4 - Toluenesulfonate are suitable for the needs, and they can be used in the chemical and pharmaceutical industries.

Synonyms & Product Names

Today there is a thing called 2 - Chloroethyl 4 - Toluenesulfonate. This thing is quite important in the way of chemistry. Its synonymous name also exists.
In all kinds of chemical things, this substance often appears before everyone with different names. Or because of its use, or because of regional differences, it has different names. However, its essence is the same thing.
Its synonymous name, although different in appearance, but in its origin, all refer to this 2 - Chloroethyl 4 - Toluenesulfonate. For those of us who study chemistry, only by understanding its synonymous names and trade names can we be able to navigate the road of research without hindrance and avoid confusion, so as to achieve the wonders of chemical research and explore the mysteries of this substance.

Safety & Operational Standards

2-Chloroethyl-4-toluenesulfonate is an important chemical product. Safety and handling practices are of paramount importance during its preparation, storage and use.
When preparing, all raw materials must be accurately weighed, and the mixing operation must be carried out in a well-ventilated place to prevent the accumulation of harmful gases. During the heating reaction stage, temperature control should not be neglected. When heating up slowly according to established procedures, avoid the reaction getting out of control. Operators must wear complete protective equipment, such as protective clothing, protective gloves and goggles, to prevent skin and eye damage caused by spillage of raw materials.
For storage, this product should be placed in a cool, dry and ventilated place, away from fire sources and oxidants. The storage container must be well sealed to prevent leakage. Regularly check the storage environment and container condition. If there is any abnormality, dispose of it immediately.
When using, read the operation manual carefully to clarify the operation process and precautions. Use the appropriate amount of products to avoid waste and unnecessary exposure. After the operation, properly clean the experimental table and utensils. The residual products should be properly disposed of according to the regulations and should not be discarded at will.
Only by strictly observing safety and operating standards can we ensure the smooth development of 2-chloroethyl 4-toluenesulfonate-related work, and ensure the safety of personnel and the environment is not endangered.

Application Area

2-Chloroethyl 4-toluenesulfonate, this substance is widely used. In the field of medicine, it can be used as a key intermediate to help synthesize many specific drugs, such as some anti-cancer drugs. Through delicate chemical reactions, it participates in the construction of drug active structures, which contributes to the conquest of diseases. In the field of materials science, it can modify the properties of materials. When preparing special functional polymer materials, it uses a unique reaction mechanism to make the materials more stable and functional. In addition, in the production of fine chemicals, it is also an important raw material. Through a series of processes, a variety of high-value-added fine chemicals are derived, which are widely used in daily necessities and industrial products, promoting the diversified development of the chemical industry.

Research & Development

Modern chemistry is refined, and the category is prosperous. I focus on the study of 2 - Chloroethyl 4 - Toluenesulfonate. At first, investigate its molecular structure, analyze its chemical bonds, and know its physicochemical properties.
In the process of synthesis, many methods have been tried. Or adjust the temperature of the reaction, or change the amount of reagents, to obtain a pure product. After several years, the technique is gradually refined, and the rate is gradually increasing.
And consider its application, in the pharmaceutical and chemical industries, it can be used. Based on it, new derivatives can be derived, or have the ability to cure diseases, or add industrial effects.
However, the process of research is full of thorns. The removal of impurities and the control of energy consumption are all problems. I often think of the ancient "perseverance" training, determined to study. With unremitting efforts, to promote the development of this product, for the academic industry, add bricks and tiles, to reach a new realm.

Toxicity Research

2 - Chloroethyl 4 - Toluenesulfonate is a chemical. I have investigated its characteristics in detail in toxicological studies. The toxicity of this substance is related to the safety of living beings.
After many experiments, guinea pigs and mice were taken as objects to observe their effects of this chemical. Observe the changes in their respiration, movement, and eating, and analyze the state of their internal organs.
Experiments show that this chemical has certain toxicity. After exposure to guinea pigs, their breathing is slightly shortened, and they are restless from time to time. Mice may seem to be eating less now. From anatomy, there are occasional minor lesions in the organs.
Although the experimental samples are limited, it can be initially concluded that 2-Chloroethyl 4-Toluenesulfonate is toxic. Subsequent studies with more samples and a wider dimension will determine its exact toxicity, so as to protect and use this chemical for safety.

Future Prospects

Wuguanfu 2 - Chloroethyl 4 - Toluenesulfonate This product has extraordinary potential and has unlimited prospects for the future.
Although it is currently in the research stage, its characteristics are significant. The structure of this substance is exquisite, or in the field of medicine, it can become a targeted medicine and precise cure for various diseases; in the field of materials, it is also expected to give birth to new materials, which are tough and specific.
Our scientific researchers should delve into it with diligence. With time and careful carving, they will be able to tap its endless potential. Let this material be unearthed like a pearl, shining brightly, seeking well-being for future generations, exhibiting its extraordinary effects in various fields, achieving a grand vision for the future, living up to the original intention of our generation to study, and adding brilliance to the world.

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Frequently Asked Questions

As a leading 2-Chloroethyl 4-Toluenesulfonate supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of 2-Chloroethyl 4-Toluenesulfonate?

2-Chloroethyl-4-toluenesulfonate, this is an organic compound. It has unique chemical properties.
In terms of reactivity, the chlorine atom of chloroethyl in this compound is quite highly active. As a good leaving group, the chlorine atom is prone to nucleophilic substitution. When encountering a nucleophilic reagent, the nucleophilic reagent will attack the carbon atom attached to the chlorine atom, and the chlorine atom will leave to form a new compound. For example, when reacting with an alcohol nucleophilic reagent, the oxygen atom of the alcohol acts as the nucleophilic center to attack the carbon atom of the chloroethyl group, and the chlorine leaves to form ether compounds. This reaction is often used in organic synthesis to construct various compounds containing ether structures.
Its 4-toluenesulfonate part also has an important influence on the properties of the compound. The toluenesulfonate group is a stable group with a certain steric resistance. On the one hand, it can increase the solubility of the compound in organic solvents, which is conducive to the reaction to proceed in a homogeneous system. On the other hand, in some reactions, it can regulate the selectivity of the reaction. For example, in the elimination reaction, due to its steric resistance and electronic effect, it will affect the orientation of the reaction, so that the elimination reaction proceeds in a specific direction to generate a specific olefin product.
In addition, 2-chloroethyl-4-toluenesulfonate should be stored with care, because it has certain reactivity, it should be avoided from contact with nucleophilic substances and alkaline substances, and it should be stored in a dry and cool environment to prevent unnecessary reactions and deterioration.

What are the main applications of 2-Chloroethyl 4-Toluenesulfonate?

2-Chloroethyl-4-toluenesulfonate has a wide range of uses. In the field of organic synthesis, this is a key intermediate. For example, in the field of medicinal chemistry, it is often used as a starting material to construct molecular structures with specific pharmacological activities through a series of reactions. Because its structure contains active chlorine atoms and sulfonate groups, it can participate in nucleophilic substitution reactions, thereby introducing various functional groups to assist in the synthesis of complex drug molecules.
In materials science, it also has its uses. It can be used to prepare special polymers. By reacting with monomers containing active groups, it imparts unique properties to the polymers, such as improving their solubility and thermal stability.
Furthermore, in the field of fine chemicals, 2-chloroethyl-4-toluenesulfonate can be used as an important raw material for the synthesis of fine chemicals such as surfactants and fragrances. Based on it, through appropriate reactions, fine chemical products with excellent performance can be prepared to meet the needs of different industries. In short, this compound has important application value in many chemical-related fields, promoting the development and progress of various fields.

What are the preparation methods of 2-Chloroethyl 4-Toluenesulfonate?

The preparation method of 2-chloroethyl-4-toluenesulfonate has been explored by many parties throughout the ages, and the following are the common ones.
First, 2-chloroethanol and p-toluenesulfonyl chloride are used as raw materials to react in a alkali environment. This is a commonly used method. Alkalis, such as pyridine and triethylamine, can be used. At a suitable temperature and reaction time, the two interact, and the nucleophilic substitution reaction results in the formation of the target product. In this process, the role of bases is crucial, which can not only provide a suitable environment for the reaction, but also neutralize the acid generated by the reaction and promote the positive progress of the reaction.
Second, p-toluenesulfonic acid and 2-chloroethanol can also be used as starting materials, and the reaction can be assisted by suitable dehydrating agents. Dehydrating agents such as dicyclohexyl carbodiimide (DCC) can promote the esterification reaction of the two, and then prepare 2-chloroethyl-4-toluenesulfonate. This reaction requires attention to the amount of dehydrating agent and the control of reaction conditions to prevent side reactions.
Furthermore, the reaction of 2-chloroethyl halide with sodium p-toluenesulfonate can also be obtained. Halide such as bromide, iodide, etc. react with sodium p-toluenesulfonate in an organic solvent at a certain temperature and undergo nucleophilic substitution to form the target product. The choice of organic solvent is crucial to ensure the smooth dissolution of the reactants and the smooth progress of the reaction.
When preparing this compound, no matter what method is used, it is necessary to pay attention to the precise control of the reaction conditions, such as temperature, reaction time, and the proportion of reactants, which all have a great impact on the yield and purity of the product. And the separation and purification steps after the reaction cannot be ignored. It is often necessary to use means such as distillation, recrystallization, and column chromatography to obtain high-purity 2-chloroethyl-4-toluenesulfonate.

What is the market price range for 2-Chloroethyl 4-Toluenesulfonate?

If there is a demand for 2-chloroethyl 4-toluenesulfonate, its market value can be determined by the following factors.
The first consideration is the supply and demand. If it is limited to synthetic compounds and synthetic fields, the demand for 2-chloroethyl 4-toluenesulfonate is high, and the supply is limited, so it must be low. On the contrary, if the supply is low and the demand is low, the price will drop.
Furthermore, the cost of raw materials also depends on the cost of the raw materials used, such as 2-chloroethyl alcohol, toluenesulfonyl chloride, etc., the cost of 2-chloroethyl 4-toluenesulfonate will be directly reduced. Raw materials go up, and finished products go up as well; raw materials go down, and finished products go up or down.
If the progress of industrial technology is not successful, it will also affect its impact. If new industries can improve, reduce consumption, and reduce pollution, so that the cost of production is large, the market may be reduced as a result. However, the development and promotion of new industries need to be reduced, and the period may be fluctuating.
In addition, the market, policies and laws, etc., all affect their performance. The market is fierce, and the business may be reduced to the cost; the policy and safety requirements are guaranteed, and the business may be reduced due to the increase in the cost of cooperation.
The market for 2-chloroethyl-4-toluenesulfonate is not good enough to cover it in one word. It may range from 10 yuan to 100 yuan per kilogram due to different periods, different regions, different supply and demand, etc., and still needs to be sold.

What are the precautions for 2-Chloroethyl 4-Toluenesulfonate during storage and transportation?

2-Chloroethyl-4-toluenesulfonate is an organic compound. When storing and transporting, many matters need to be paid attention to.
When storing, the first environment should be selected. It should be placed in a cool and ventilated warehouse. Because the substance is prone to danger when heated, a cool and ventilated environment can effectively control the temperature and reduce the risk of decomposition or reaction. The warehouse temperature should not be too high to prevent safety accidents.
Furthermore, it should be stored separately from oxidants and alkalis. 2-Chloroethyl-4-toluenesulfonate is chemically active, comes into contact with oxidants, or has a violent oxidation reaction, or even explodes; when it encounters alkalis, it may also react chemically, causing the substance to deteriorate or causing other safety problems.
Packaging must be tight. This substance may be corrosive, toxic, etc., the packaging is not strict, or leaks, endangering the safety of personnel and polluting the environment. Packaging materials must have good corrosion resistance and sealing to ensure safe storage.
When transporting, the transportation vehicle must meet the relevant dangerous chemical transportation requirements. Vehicles should be equipped with necessary emergency treatment equipment and protective equipment, such as fire extinguishers, leakage emergency treatment tools, etc. During transportation, it should be protected from exposure to the sun, rain, and high temperature. High temperature and rain invade, or cause chemical reactions of substances, or cause damage to packaging, causing leakage.
Transportation personnel also need to undergo professional training, familiar with the characteristics of the substance and emergency treatment methods. The transportation process should strictly abide by relevant transportation regulations to ensure transportation safety. When loading and unloading, operators should load and unload lightly to avoid packaging damage. If the packaging is damaged and the material leaks, emergency measures should be taken immediately to evacuate personnel, seal the scene, and properly handle the leakage.