2-Deoxy-2,2-Difluoro-D-Erythro-Ribofuranose-3,5-Dibenzoate 1-Methanesulfonate

This is related to the chemical structure of 2-deoxy-2,2-difluoro-D-erythrofuran-3,5-dibenzoate-1-methanesulfonate. In its structure, the nucleus of the furan is a five-membered ring structure, and the oxygen atom is located in one corner of the ring. On the 2nd carbon, two fluorine atoms replace the conventional hydroxyl and hydrogen atoms, resulting in deoxygenation and difluorination. The 3rd and 5th carbon are respectively connected to the benzoate group, which is composed of a benzene ring and an ester group, giving the molecule specific chemical properties and steric resistance. The 1-bit carbon is connected to the methanesulfonate group. The methanesulfonate part contains sulfur-oxygen double bonds and methyl groups, which has a great impact on molecular reactivity. The unique combination of this structure gives the compound unique physical and chemical properties. It may have specific uses in organic synthesis, pharmaceutical chemistry and other fields. The interaction and spatial arrangement of its groups determine its ability and way to participate in various chemical reactions.

2-Deoxy-2,2-difluoro-D-red-furan-ribose-3,5-dibenzoate-1-methanesulfonate, which is widely used in the field of medicinal chemistry, is often the key intermediate for the synthesis of characteristic nucleoside compounds. Nucleoside drugs have extraordinary effects in many therapeutic fields such as antivirus and anti-tumor. Due to their unique chemical structure, this compound can introduce special groups into nucleoside drug molecules, enhance the affinity between drugs and targets, improve stability, and optimize pharmacokinetic properties, so it plays an important role in the process of creating new high-efficiency nucleoside drugs.
In the field of organic synthesis, it is also an important building block for the construction of complex carbon rings and heterocyclic systems. Because its structure is rich in modifiable check points, chemists can use a variety of organic reactions to derive and construct a variety of novel and potentially bioactive compound skeletons, which help explore and innovate in the fields of new drug development and materials science.
In the study of carbohydrate chemistry, it helps to deeply understand the relationship between carbohydrate structure and function. Through the study of the structural modification and reaction characteristics of this compound, the secrets of carbohydrate metabolism pathways and identification mechanisms in organisms can be revealed, which lays a theoretical foundation for the development of carbohydrate-related drugs and the design of bioactive molecules, and promotes the continuous development of carbohydrate chemistry.

To prepare 2-deoxy-2,2-difluoro-D-erythrofuran-3,5-dibenzoate-1-methanesulfonate, the method of synthesis is very delicate. First of all, suitable starting materials, such as sugar derivatives with specific configurations, are the basis for synthesis.
First, take the sugar body, use benzoic anhydride and suitable base as the medium, under mild reaction conditions, such as in an inert solvent, moderate temperature control, so that the hydroxy groups of the sugar body at the 3rd and 5th positions are esterified with benzoic anhydride, and 3,5-dibenzoic acid ester-modified sugar derivatives can be obtained. In this step, it is necessary to pay attention to the reaction process to ensure the complete reaction and avoid the growth of by-products due to excessive reaction.
Second, esterification of methanesulfonate is carried out on the 1-position hydroxyl group. Take the above product and react with methanesulfonyl chloride in the presence of a base. The choice of base is very important, which needs to effectively promote the reaction without damaging other parts of the molecule. The reaction solvent should also be carefully selected to facilitate the homogeneity of the reaction. At this step, the reaction temperature and time are strictly controlled to prevent side reactions.
Furthermore, the 2-deoxy-2,2-difluoro structure is introduced under specific conditions. Fluoride-containing reagents are often used to introduce this special structure into the second position of the sugar ring through delicate reaction mechanisms, such as nucleophilic substitution. The reaction conditions in this step are harsh, and factors such as temperature and reagent ratio need to be precisely adjusted to obtain the target product.
After each step of the reaction, it needs to be carefully separated and purified, such as column chromatography, recrystallization, etc., to remove impurities and obtain a pure product. In this way, the steps are interlocked and delicately coordinated to obtain 2-deoxy-2,2-difluoro-D-red-furan-ribose-3,5-dibenzoate-1-methanesulfonate.

2-Deoxy-2,2-difluoro-D-red-furan-ribose-3,5-dibenzoate-1-methanesulfonate, is an organic compound. It has unique physical properties.
Looking at its appearance, it is often in the form of white to off-white crystalline powder, which is easy to observe and handle. Regarding the melting point, it is in a specific temperature range, which can be used for identification and purity determination. The solubility of this compound in organic solvents is considerable. For example, in common organic solvents such as dichloromethane and chloroform, it can exhibit good solubility. This is very critical for its operation in organic synthesis reactions, because it can fully mix the reactants and promote the smooth progress of the reaction.
However, its solubility in water is poor, which limits its application in systems involving aqueous phases. Furthermore, the stability of the compound is also an important property. Under normal temperature and humidity conditions, it can maintain a relatively stable chemical structure. However, when exposed to strong acids, strong bases or high temperature environments, its structure may change, resulting in changes in chemical properties.
Its density is also a specific value, this physical parameter is of great significance in some processes involving precise measurement or separation. And it has a certain refractive index, which can be used as an important reference in the analysis and identification process. In summary, the physical properties of 2-deoxy-2,2-difluoro-D-red-furan-ribose-3,5-dibenzoate-1-methanesulfonate have far-reaching implications for its applications in organic synthesis, drug development and other fields.

There are currently 2-deoxy-2,2-difluoro-D-erythrofuran-3,5-dibenzoate-1-methanesulfonate compounds, and their market prospects are related to many aspects.
From the perspective of the pharmaceutical field, due to its unique chemical structure, it may have potential value in the development of new antiviral and antitumor drugs. In today's pharmaceutical industry, there is a strong demand for antiviral and antitumor drugs. If this compound can exhibit unique pharmacological activities through in-depth research and development, it may open the door to new drug categories and gain a place in the market.
In the chemical industry, it can be used as a special organic synthesis intermediate. With the vigorous development of the fine chemical industry, there is a growing demand for high-purity, special-structured intermediates. The structural characteristics of this compound may make it a key raw material for the synthesis of many high-end chemicals. If large-scale production can be achieved and meet the needs of the chemical industry to upgrade, the market prospect is also promising.
However, its marketing activities also pose challenges. The synthesis process may be complex and expensive, limiting large-scale production and application. And the research and development of new drugs requires a long cycle and huge investment. From the discovery of compounds to the launch of new drugs, it requires multiple rounds of experiments and approval, which is quite risky.
Overall, 2-deoxy-2,2-difluoro-d-erythrofuran-3,5-dibenzoate-1-mesylate has an addressable market opportunity, but also needs to overcome the synthesis and R & D problems in order to shine in the market.