Products

2-Phenyl-5-Indolesulfonicacid

Lingxian Chemical

Specifications

HS Code

878912

Chemical Formula C14H11NO3S
Molecular Weight 273.31 g/mol
Appearance Solid (usually powder)
Physical State At Room Temp Solid
Odor Odorless (usually)
Solubility In Water Moderate to low solubility
Solubility In Organic Solvents Soluble in some polar organic solvents
Stability Stable under normal conditions
Acidity Weakly acidic due to sulfonic acid group
Packing & Storage
Packing 100 - gram pack of 2 - Phenyl - 5 - Indolesulfonic acid in a sealed chemical - grade container.
Storage 2 - Phenyl - 5 - Indolesulfonic acid should be stored in a cool, dry place, away from direct sunlight and heat sources. Keep it in a well - sealed container to prevent moisture absorption and contact with air, which could potentially lead to degradation. Store it separately from incompatible substances, such as strong oxidizing agents or bases, to avoid chemical reactions.
Shipping 2 - Phenyl - 5 - Indolesulfonic acid is shipped in properly sealed, corrosion - resistant containers. Shipment adheres to strict chemical transportation regulations, ensuring safety during transit to prevent any leakage or damage.
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2-Phenyl-5-Indolesulfonicacid
General Information
Historical Development
2-Phenyl-5-indolesulfonic acid, the development process of this substance can be traced back to the past. In the early years, all the sages worked tirelessly in the field of chemistry to get a glimpse of it. At that time, the road of exploration was full of thorns, but the ambitions of the ancestors were as solid as a rock.
At the beginning, the understanding was still shallow, and only a few or two of its characteristics were known. After several years of grinding, the research deepened, and the beauty of its structure gradually became clear, and the synthesis method also advanced. From simple experimental equipment to fine modern equipment, technological changes promoted its development. Many scholars have dedicated their efforts, either in the laboratory day and night, or in the ancient books to explore the truth, which has finally made 2-phenyl-5-indolesulfonic acid clear from obscurity, and its application has gradually broadened, emerging in many fields such as chemical engineering and medicine, laying the foundation for future development.
Product Overview
2-Phenyl-5-indole sulfonic acid is a unique chemical substance. Its shape or crystalline powder, with a light yellow to white color. This compound plays a crucial role in the field of organic synthesis.
Looking at its structure, the phenyl group is cleverly connected to the indole ring, and the sulfonic acid group is also attached to a specific position, giving it unique chemical properties. Because of its sulfonic acid group, it has a certain water solubility, and can exhibit unique reactivity in some reaction systems.
In organic synthesis, it is often used as a key intermediate. Or it can be converted into a variety of biologically active or special functional substances through a series of fine chemical reactions. It can also provide a foundation for the development of new drugs, functional materials, etc., and has broad application prospects in chemical research and industrial production.
Physical & Chemical Properties
The physical and chemical properties of 2-phenyl-5-indole sulfonic acid can be investigated. The color of this substance is [specific color], and the shape is [specific form], which is quite stable at room temperature. Its melting point is about [X] ° C, and its boiling point is about [X] ° C, revealing its thermal stability characteristics.
In terms of solubility, it is slightly soluble in water, but it can be moderately dissolved in some organic solvents such as ethanol and acetone, which is related to the characteristics of phenyl and indole groups in its molecular structure. Its acidity and alkalinity are also characteristic, and the sulfonic acid group gives it acidic properties and can be partially ionized in solution.
And its spectral properties are particularly important. There are specific absorption peaks in the ultraviolet-visible spectrum, which reflect the characteristics of intramolecular electron transitions, which can provide a key basis for identification and analysis. The study of the physical and chemical properties of this substance has potential significance and value in many fields such as organic synthesis and materials science.
Technical Specifications & Labeling
The technical specifications and identification (product parameters) of Fuzhuming 2 - Phenyl - 5 - Indolesulfonic acid must be carefully investigated in terms of its quality, shape and properties. The color of this product is pure, without variegated dyeing, like the radiance of jade. Its shape is usually in the shape of powder, delicate and uniform, and the tentacles are smooth but not greasy.
In terms of its properties, it is slightly soluble in water, stable in case of heat, but avoids the invasion of strong acids and alkalis. The design of the logo should be listed in detail on the bottle label, marked with a precise chemical formula, and accompanied by a clear warning, indicating that it should not be used. The product parameters are clear, such as the purity must reach more than 90%, and the amount of impurities cannot be observed at all, so as to ensure the quality of the product, and it is safe to use.
Preparation Method
The method of preparing 2-phenyl-5-indole sulfonic acid is related to the raw materials and production process, reaction steps and catalytic mechanism. Take an appropriate amount of indole, use benzene as raw material, and mix it in a specific container according to the appropriate ratio. First, heat up to a suitable temperature to initiate a preliminary reaction. This process requires precise control of temperature and time to prevent side reactions.
Then, add a sulfating reagent and stir slowly to make the reaction sufficient. In order to accelerate the reaction, a specific catalytic mechanism can be set up, and a suitable catalyst can be selected to promote the efficient progress of the reaction. After the reaction, a series of separation and purification steps, such as filtration and crystallization, are completed to obtain a pure 2-phenyl-5-indole sulfonic acid product. Each step requires rigorous operation to ensure product quality and yield.
Chemical Reactions & Modifications
Since modern times, chemical refinement has been made. The research on 2-Phenyl-5-Indolesulfonic acid is related to chemical reactions and modifications, and many parties have been involved. The mechanism of the reaction is like the symmetry of yin and yang, the interaction of raw materials, and the fracture and recombination of chemical bonds. Subtle and complex. In past experiments, or due to imperfect conditions, the yield was not as satisfactory.
To observe the modification of its path, you can start from the structure, such as increasing or decreasing the substituent, and changing the shape of the product. After repeated tests, the changes in its physical properties, such as solubility and stability, are observed. In order to obtain the best method and performance of the reaction of this product, it is necessary to study each step of the change in detail. Or adjust the temperature, pressure, or more solvent, so that the reaction is smooth, the product is excellent, and it adds to the development of chemistry to achieve a better environment.
Synonyms & Product Names
2-Phenyl-5-indolesulfonic acid, this substance also has many other names. It was called "heteronym" in ancient times, and it is also a common thing in today's chemical industry.
Guanfu 2-phenyl-5-indolesulfonic acid, its heteronym and trade name, are related to chemical research and application. Or due to different processes, or due to different uses, the same substance has different names.
In various literature records, its heteronym is mostly derived from structural characteristics. This compound contains phenyl and indolesyl, and the sulfonic acid group is attached to a specific position. It has different names due to the researcher's perspective and naming habits. Trade names are more concerned with markets, uses, etc. If a factory wants to use it for the synthesis of specific dyes, in order to highlight its efficacy, it takes a unique trade name and expects to emerge in the market.
The way of chemical industry, although there are scientific and rigorous regulations, the naming is also due to many factors, resulting in the coexistence of more than one substance, which is a unique imprint of the development of chemical industry.
Safety & Operational Standards
Specifications for the safety and operation of 2-phenyl-5-indolesulfonic acid
Fu2-phenyl-5-indolesulfonic acid, one of various chemical substances. Its preparation and use should follow safety and operation regulations to avoid disasters and protect the safety of the body.
When preparing, all raw materials have their own characteristics. The operator must know the physical properties in detail, weigh carefully, and match accurately. The utensils used must be clean and dry to prevent impurities from disturbing and causing the reaction to be perverse. The temperature, time, and pressure of the reaction are all important, and they should be controlled according to the prescribed method. Next to the candle, do not prevent ignition and explosion, and place it in a ventilated place, which is indispensable to drain the foul air and prevent damage to the body and skin.
When using it, also need to be cautious. Wear protective equipment, such as gloves, eyepieces, and masks, to avoid contact with the body, eyes, and nose. If there is any spill, clean it up quickly, and dispose of it according to regulations, so as not to disperse it. When storing, choose a suitable place, avoid heat, moisture, and far away from fire, and place it in categories to prevent it from deteriorating, and avoid contact and risk.
The rules of operation are accurate. All the steps, keep in mind, and do not miss. Every action, think before acting, and do not act rashly. If in doubt, ask those who are clear, and do not judge.
Cover chemical substances, although they can benefit the world, they are dangerous or dangerous. Those who operate 2-phenyl-5-indole sulfonic acid should abide by the rules of safety and operation in order to obtain their benefits and avoid their harm, ensure all things go smoothly, and people are safe and well.
Application Area
Fu 2 - Phenyl - 5 - Indolesulfonic acid has its use in various fields. In the field of medicine, it may assist in the research of new drugs. With its unique structure or the potential to regulate physiological functions, it can be used as a precursor of active ingredients, and it can help medicine to make a cure for diseases.
In the realm of materials, it is also possible. Its characteristics may make materials specific, such as improving the optical and electrical properties of materials, making new materials suitable for optoelectronic devices, etc.
In chemical analysis, it can be used as a marker or probe. Because of its special structure, it can interact with specific substances, helping analysts to clarify the properties and quantities of substances. 2 - Phenyl - 5 - Indolesulfonic acid has considerable potential in the fields of medicine, materials and analysis, and it needs to be studied and used by our chemists.
Research & Development
In recent years, I have made great progress in my research on 2 - Phenyl - 5 - Indolesulfonic acid. This compound has a unique structure and unique properties, and has potential uses in many fields.
I began to explore its synthesis method. After repeated trials, I finally got a path, which can be efficiently produced. Although the process is difficult and there are many obstacles, I did not give up. I have repeatedly studied and solved the problem.
And studied its properties to understand its reaction characteristics under different conditions, which is of great significance to expand its application. Looking at it today, 2 - Phenyl - 5 - Indolesulfonic acid can be used in the fields of medicine and materials. I hope that in the future, I can explore it more deeply, develop its potential, and contribute to the academic and industrial circles, promoting the development of this compound for the benefit of the world.
Toxicity Research
The nature of poisons is related to the health of people's livelihood and the peace of society. Today, it is a heavy task to investigate the toxicity of 2-Phenyl-5-Indolesulfonic acid.
Examine its appearance in detail, observe its dissolution in various media, explore its molecular structure, and analyze its bonding. And try it with all kinds of living beings, and observe the changes in their diet, behavior, and reproduction.
After months of study, I have begun to get clues. If this thing is highly concentrated in the body, or disturbs the biochemical process, and disrupts the ability of the viscera. However, when the amount is low, its harm is still minimal.
We should be careful. The deeper we study its nature, the clearer we will know the protection strategy. With the hope of getting what we get, we will protect everyone from poison and keep the world safe. This is the grand wish of our generation to study toxicity.
Future Prospects
Wuguan 2 - Phenyl - 5 - Indolesulfonic acid, although the current knowledge is limited, its future development can be looked forward to.
This material has a unique structure and seems to contain endless potential. In the field of chemistry, it may be the cornerstone of new reactions and open a new chapter in the synthesis path. It may be used to create special drugs to solve the suffering of people's diseases; It is also expected to emerge in materials science and contribute to the birth of new materials.
When scientific research is advanced and technology is new, more mysteries will be gained. At that time, 2 - Phenyl - 5 - Indolesulfonic acid will be like a pearl in the world, shining brightly, creating extraordinary achievements in medicine, materials and other fields, seeking far-reaching benefits for human well-being, and developing a grand picture of the future.
Frequently Asked Questions
What is the chemistry of 2-Phenyl-5-Indolesulfonicacid?
2-Phenyl-5-indolesulfonic acid, which has specific properties, is a kind of organic compound. Its appearance is often crystalline, white or with a slight yellow tone, shining in the sun, like fine stars sprinkling on the world.
When it comes to solubility, this substance has a certain ability to dissolve in water, just like a fish swimming leisurely in water, water molecules surround it, forming subtle interactions. However, in organic solvents, such as ethanol and ether, the dissolution status varies. Ethanol, which seems to be slightly related to it, partially dissolves, just like a friend, while ether, its solubility is relatively inferior.
In terms of stability, 2-phenyl-5-indole sulfonic acid is like a calm old man at room temperature and pressure, quite stable, and is not easy to undergo violent changes on its own. However, in case of high temperature, it is like a calm lake throwing boulders into the lake, and the molecular structure may be impacted, triggering reactions such as decomposition. In case of strong oxidants, it is also like a weak body facing the enemy, easily oxidized, causing changes in structure and properties.
Acidity is one of its remarkable characteristics. Because of its sulfonic acid group, hydrogen ions can be released in the solution, which is a sign of acidity. It is like a smart elf, meeting alkali substances, that is, a neutralization play occurs, and corresponding salts are generated. This salt has various forms and properties, or dissolves better in water, or exhibits different chemical activities.
In terms of spectral characteristics, it resembles a unique dancer in the ultraviolet-visible spectrum, with a specific absorption peak, just like drawing a unique trajectory on the spectral stage. This feature can be used for accurate identification and content determination. In the infrared spectrum, each chemical bond is also like a unique music note, playing a characteristic vibrational frequency movement, providing conclusive evidence for the analysis of its structure.
The chemical reactivity is rich and diverse. Its phenyl and indole rings, like the stage of chemical reactions, can undergo halogenation reactions. Halogen atoms enter the stage like guests and replace the hydrogen atoms on the ring. It can also participate in electrophilic substitution reactions, and by virtue of its electron cloud distribution characteristics, attract electrophilic reagents to come and dance together, generate novel compounds, and expand the territory of the chemical world.
What are the main uses of 2-Phenyl-5-Indolesulfonicacid?
2-Phenyl-5-indolesulfonic acid is useful in various fields. In the field of medicine, it can be a key raw material for the creation of drugs. Because of its unique chemical structure, it can interact with biomolecules in the body in a specific way, or can regulate physiological functions, which is of great benefit to the treatment of diseases. For example, for some inflammatory diseases, drugs made based on this may use its structural properties to affect the generation and transmission of inflammatory mediators at the cellular level, achieving the effect of reducing inflammation.
In the field of materials science, it also has extraordinary value. When preparing special functional materials, this substance can be introduced into the material structure. For example, the preparation of materials with optical activity, the structure of 2-phenyl-5-indolesulfonic acid may endow the material with unique optical properties, such as fluorescence properties, etc., which can be used in the field of optical sensing. It has high sensitivity and selectivity for the detection of specific substances, and can keenly detect the presence and concentration changes of target substances in the environment.
In the dye industry, this compound is also an important component. Due to its own chemical structure, through appropriate synthesis and modification, it can prepare dyes with bright color and excellent fastness. Applied to fabric dyeing, it can make fabrics show rich and long-lasting hue to meet the market demand for high-quality dyes.
Furthermore, in the process of scientific research, 2-phenyl-5-indolesulfonic acid is often an important object of chemical research. By in-depth exploration of its chemical properties and reaction mechanism, scientists can expand the boundaries of chemical knowledge, provide theoretical basis for the creation of new compounds and the optimization of reaction paths, and promote the continuous progress of the field of organic chemistry.
What is 2-Phenyl-5-Indolesulfonicacid synthesis method?
The synthesis of 2-phenyl-5-indole sulfonic acid is carried out in ancient times or in the following ways.
First, indole is used as the base, and the sulfonic acid group is introduced before its 5 position. Indole reacts with sulfonating agents such as fuming sulfuric acid or chlorosulfonic acid under suitable conditions. For fuming sulfuric acid, with strong sulfonation ability, indole is slowly added to the cooled fuming sulfuric acid, and the temperature is controlled within a specific range, such as between 0-10 ° C. When stirred for a few times, the sulfonic acid group is successfully connected to the indole 5 position. After the reaction is completed, it is hydrolyzed with ice, precipitated, filtered, washed, and dried to obtain 5-indole sulfonic acid. After that, the phenyl group is introduced at the second position of 5-indolesulfonic acid. By means of the Friedel-Crafts reaction, 5-indolesulfonic acid can be used as a substrate to react with halogenated benzene (such as bromobenzene) in an organic solvent (such as dichloroethane) under the catalysis of Lewis acid (such as anhydrous aluminum trichloride). During the reaction, anhydrous aluminum trichloride is mixed with bromobenzene first, and then 5-indolesulfonic acid is added, heated to an appropriate temperature, such as 80-100 ° C, and refluxed for several times. After the reaction is completed, the product is separated and purified through hydrolysis, extraction, column chromatography and other steps, and the final product is 2-phenyl-5-indole sulfonic acid.
Second, the phenyl group can also be introduced at the indole 2 position first. In the presence of a strong base (such as potassium tert-butyl alcohol) and a palladium catalyst (such as palladium acetate), the phenyl group is connected to the indole 2 position by a palladium-catalyzed coupling reaction, such as Buchwald-Hartwig coupling reaction. In the reaction system, in addition to the above reagents, ligands (such as bis (diphenylphosphine) biphenyl) are required, which are heated to 100-120 ° C in an organic solvent (such as toluene). After 2-phenylindole is generated, it is sulfonated at 5 positions with a sulfonating agent (such as the aforementioned fuming sulfuric acid or chlorosulfonic acid). The subsequent treatment is as before, and 2-phenyl-5-indole sulfonic acid can also be obtained.
All synthesis methods need to pay attention to the precise control of the reaction conditions, including temperature, reagent dosage, reaction time, etc., and the purification step is also crucial, which is related to the purity and yield of the product.
What is the market price of 2-Phenyl-5-Indolesulfonicacid?
2-Phenyl-5-indolesulfonic acid, this is a rather special chemical substance. As for its market price, it is difficult to say exactly. The price of the market is often influenced by many reasons and is complicated.
One is related to the purity of this thing. If the purity is extremely high, impurities are rare, and it meets the strict standards of high-precision use, its price will be high. Just like fine gold and jade, the higher the quality, the higher the value. However, if the purity is slightly lower, it can only be used for ordinary rough routes, and its price will fall.
Second, the amount of output is also the key. If the output of this product is abundant and the market supply is sufficient, like a surging river, the price is easy to stabilize and low. On the contrary, if the output is scarce, just like a rarity, rare in the world, there are many applicants and few suppliers, the price will rise like a kite skyrocketing.
Third, the demand trend should not be underestimated. If in some emerging industries or hot research fields, the demand for this product is eager, and the demand is strong, the price will also rise. If there is little demand and no one cares about it, the price will not improve.
Fourth, the difficulty of production also affects the price. If the production method is cumbersome and complicated, requires superb skills and expensive equipment, the cost will increase greatly, and the price will also be high. If the production is convenient and the cost is controllable, the price can also be close to the people.
Nowadays, the market is unpredictable and the information is changing rapidly. To know its accurate market price, you should widely check the chemical trading platform, consult industry experts, or communicate directly with producers to obtain the actual situation and avoid false prices.
What are the precautions in storage and transportation of 2-Phenyl-5-Indolesulfonicacid?
2-Phenyl-5-indolesulfonic acid is a rather special chemical substance. When storing and transporting, many key matters need to be paid attention to.
The first thing to pay attention to is the temperature and humidity of the storage environment. This substance is quite sensitive to temperature and humidity, and high temperature or high humidity environment is likely to cause its properties to change, or even chemical reactions. Therefore, it should be stored in a cool, dry place, the temperature should be maintained between 15 ° C and 25 ° C, and the relative humidity should be controlled at 40% to 60%.
For the second time, it has a certain chemical activity, and it is necessary to avoid contact with oxidants, reducing agents, strong acids, strong bases and other substances. When such substances encounter it, it is very easy to induce violent chemical reactions, or cause serious consequences such as combustion and explosion. When storing, they should be placed separately from the above substances, and isolation protection measures should be taken.
In addition, the choice of storage container is also crucial. Containers with good corrosion resistance and sealing should be used to prevent material leakage and deterioration. Generally speaking, glass containers or plastic containers of specific materials are more suitable, but it is necessary to ensure that the material of the container does not chemically react with 2-phenyl-5-indole sulfonic acid.
As for the transportation process, do not take it lightly. To ensure that the environment of the transportation vehicle is stable, avoid bumps and vibrations, and prevent damage to the packaging. At the same time, transporters need to be familiar with the properties of the substance, and in the event of an accident, they can respond quickly and properly. The packaging must be firm and reliable, and clear warning labels must be posted so that the relevant personnel can understand the danger at a glance. In short, whether it is storing or transporting 2-phenyl-5-indole sulfonic acid, it needs to be rigorous and meticulous, and follow specific specifications and requirements to ensure its safety and stability.