As a leading (2Alpha,6Alpha,8Alpha,9Abeta)-Octahydro-3-Oxo-2,6-Methano-2H-Quinolizin-8-Yl-1H-Indole-3-Carboxylate Monomethanesulfonate supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
(2Alpha, 6Alpha, 8Alpha, 9Abeta) -Octahydro-3-Oxo-2, 6-Methano-2H-Quinolizin-8-Yl-1H-Indole-3-Carboxylate what is the chemical structure of Monomethanesulfonate
(2α, 6α, 8α, 9a β) -octahydro-3-oxo-2,6-methylene-2H-quinazine-8-yl-1H-indole-3-carboxylate monomethanesulfonate, an organic compound with complex and delicate structure.
Looking at its structure, the core is formed by the fusion of quinazine and indole two ring systems. The quinazine ring is modified by octahydro, of which 3 positions have a carbonyl group, 2 and 6 positions are connected by methylene, forming a unique bridge-ring structure, and 8 positions are connected with indole-3-carboxylate, which is like a tenon-mortise fit to construct the main frame of the molecule. The monomethyl sulfonate part is connected to the main structure like an accessory, giving the compound specific physical and chemical properties.
The structure of this compound is like a treasure carefully carved by ancient craftsmen. The atoms echo each other to construct a stable and unique spatial configuration, exuding unique charm in the field of organic chemistry.
(2Alpha, 6Alpha, 8Alpha, 9Abeta) -Octahydro-3-Oxo-2, 6-Methano-2H-Quinolizin-8-Yl-1H-Indole-3-Carboxylate What are the physical properties of Monomethanesulfonate
(2α, 6α, 8α, 9a β) -octahydro-3-oxo-2,6-methylene-2H-quinozine-8-yl-1H-indole-3-carboxylate monomethanesulfonate has the following physical properties:
The appearance of this compound may be white to off-white crystalline powder, odorless and tasteless. Its melting point range is usually within a certain range, and the specific value varies due to purity and other factors. The solubility of the substance varies in different solvents, slightly soluble in water, and has certain solubility in organic solvents such as ethanol and chloroform, but it also depends on specific conditions.
In terms of stability, it is relatively stable at room temperature and pressure, but in case of extreme conditions such as strong acid, strong alkali or hot topic, decomposition reactions may occur, resulting in structural changes. At the same time, it is also more sensitive to light, and long-term exposure to light may cause degradation. In terms of storage, it should be placed in a cool, dry, dark place, and sealed to ensure its chemical stability and avoid contact with air, moisture and other impurities to prevent it from affecting its quality.
(2Alpha, 6Alpha, 8Alpha, 9Abeta) -Octahydro-3-Oxo-2, 6-Methano-2H-Quinolizin-8-Yl-1H-Indole-3-Carboxylate What is the main use of Monomethanesulfonate
(2α, 6α, 8α, 9Aβ) -octahydro-3-oxo-2,6-methylene-2H-quinozine-8-yl-1H-indole-3-carboxylate monomethanesulfonate This substance is quite crucial for medical use. In the field of pharmacy, it is mostly the core component of drug research and development.
Looking at the current medical research, there are many diseases to be solved. This compound is often used by developers. In neurological diseases, such as the genus Parkinson's, researchers hope that it can regulate neurotransmitters and restore the regularity of neural pathways to relieve the suffering of patients. It may interact with receptors on the surface of nerve cells, improve cell signal transduction, and promote the recovery of nerve function.
In the treatment of tumors, it is also hoped. It can inhibit the proliferation and migration of tumor cells and induce their apoptosis. With its special chemical conformation, it can block the key pathways required for tumor growth, cut off its nutrient source, and make the tumor gradually disappear.
It also has potential in the prevention and treatment of cardiovascular diseases. It can adjust blood lipids, stabilize blood pressure, protect the cardiovascular endothelium, prevent atherosclerotic changes, and reduce the risk of cardiovascular diseases.
However, the use of this thing also needs to be careful. Although it has the ability to treat diseases, its safety and side effects cannot be ignored. It is necessary to conduct detailed research and testing to clarify its pharmacology, toxicology, and appropriate dosage and usage before it can be used in clinical practice and protect the well-being of patients.
(2Alpha, 6Alpha, 8Alpha, 9Abeta) -Octahydro-3-Oxo-2, 6-Methano-2H-Quinolizin-8-Yl-1H-Indole-3-Carboxylate What is the synthesis method of Monomethanesulfonate
The synthesis of (2α, 6α, 8α, 9a β) -octahydro-3-oxo-2,6-methylene-2H-quinozine-8-yl-1H-indole-3-carboxylate monomethanesulfonate is an important matter for chemical preparation. To form this compound, its structure and properties should be clarified first. This substance has a specific spatial configuration and functional group, and each part affects each other. It needs to be carefully controlled in the synthesis.
Initial steps often involve the selection of raw materials and pretreatment. Compounds with suitable activity and reaction check points should be selected as starting materials. Or starting from indole derivatives, because they contain indole rings, are the key structural units of the target product. Make necessary modifications to it, such as introducing suitable substituents at specific positions, to facilitate subsequent reactions.
Subsequently, it is extremely important to construct key carbon-carbon bonds and functional group conversion. Or through condensation reaction, the quinazine-containing structure fragment is connected to the indole derivative. During the process, precise control of reaction conditions, such as temperature, solvent, catalyst, etc. Too high or too low temperature may cause side reactions to occur or inappropriate reaction rates.
Furthermore, forming the desired stereoconfiguration is also challenging. Or use a chiral catalyst or a specific reaction path to guide the reaction in the target stereochemical direction to ensure that (2α, 6α, 8α, 9a β) specific configuration products are obtained.
For the formation of monomethanesulfonate, methanesulfonic acid is added at an appropriate stage to react with the corresponding base or activity check point to generate the target monomethanesulfonate product.
The whole synthesis process requires fine planning of each step of the reaction, close monitoring of the reaction process, and timely adjustment of conditions to obtain the target product (2α, 6α, 8α, 9aβ) -octahydro-3-oxo-2,6-methylene-2H-quinozine-8-yl-1H-indole-3-carboxylate monomethanesulfonate.
(2Alpha, 6Alpha, 8Alpha, 9Abeta) -Octahydro-3-Oxo-2, 6-Methano-2H-Quinolizin-8-Yl-1H-Indole-3-Carboxylate Monomethanesulfonate What are the precautions during use
(2α, 6α, 8α, 9a β) -octahydro-3-oxo-2,6-methylene-2H-quinozine-8-yl-1H-indole-3-carboxylate monomethanesulfonate This product, when using, many matters must be observed.
First, be sure to read the accompanying instructions carefully. In this manual, the key reasons for use, dosage preparation, applicable diseases, and contraindications are comprehensively prepared. If you have a little doubt about what is said in it, you must not make an assertion without authorization. Please consult a professional doctor or pharmacist for clarity.
Second, pay attention to the precise control of dosage. If used in excess, it may cause a lot of adverse reactions, such as nausea, vomiting, dizziness, heart palpitations, etc., or even endanger health; if the dosage is insufficient, it will be difficult to achieve the expected effect. It must be taken according to the doctor's instructions, on time and in accordance with the amount, and should not increase or decrease on its own.
Third, pay attention to possible adverse reactions. During the medication period, if the body is suddenly abnormal, such as skin rash, itching, poor breathing, or other discomfort, you should immediately stop the medication and seek treatment at a medical office, and describe the medication situation and physical reaction in detail for the doctor to accurately judge.
Fourth, know the drug interaction. This drug may conflict with other drugs, affect the efficacy of the drug, or even breed danger. When seeking medical treatment, you must inform the doctor of all other medicines you are taking, including traditional Chinese medicine, western medicine, health products, etc., to prevent accidents.
Fifth, store properly. Store according to the conditions indicated in the instructions, or need to be protected from light and cool, or need to be refrigerated, etc. Improper storage can easily cause drug deterioration and drug efficacy loss. In this way, only when using (2α, 6α, 8α, 9aβ) -octahydro-3-oxo-2,6-methylene-2H-quinazine-8-yl-1H-indole-3-carboxylate monomethanesulfonate, seek advantages and avoid disadvantages, and protect your health.