(2R,3R)-3-(2,4-Difluorophenyl)-3-Hydroxy-4-(1H-1,2,4-Triazol-1-Yl)Butan-2-Yl Methanesulfonate

This is about the chemical structure of\ ((2R, 3R) -3- (2,4-difluorophenyl) -3-methoxy-4- (1H-1,2,4-triazole-1-yl) butyl-2-yl acetate. To clarify its structure, it is necessary to analyze it according to the naming rules of organic chemistry.
"\ ((2R, 3R) \) " shows that the configuration of the carbon atoms at the\ (2\) and\ (3\) positions in this compound is of the\ (R\) type. " \ (3- (2,4 -difluorophenyl) \) "shows that there is a\ (2,4 -difluorophenyl\) group attached to the carbon at the\ (3\) position. On this phenyl group, the fluorine atom is at the\ (2\) and\ (4\) positions."\ (3-methoxy\) "means that the carbon at the\ (3\) position also has a methoxy group."\ (4- (1H-1,2,4-triazole-1-yl) \) "Table\ (4\) carbon linked to\ (1H-1,2,4-triazole-1-yl\). The triazole ring contains three nitrogen atoms, and the nitrogen atom at the\ (1\) position is connected to the main chain. "Butyl-2-ylacetate" indicates that the main chain is a butyl structure, and the carbon at the\ (2\) position is connected to the acetate group.
In summary, this compound has a specific configuration at the\ (2\) and\ (3\) positions with butyl as the main chain, and the\ (3\) position with difluorophenyl and methoxy, the\ (4\) position with triazole, and the\ (2\) position with acetate. The groups in its structure are connected to each other to form a unique chemical structure. In this way, according to the naming rules, its chemical structure can be obtained.

(2R, 3R) -3- (2,4-difluorophenyl) -3-methoxy-4- (1H-1,2,4-triazole-1-yl) butyl-2-yl acetate, this substance has a wide range of uses. In the field of medicine, it is often used as a key intermediate for the synthesis of drugs with specific biological activities. The unique triazolyl and difluorophenyl parts of the Gain structure can interact with specific targets in organisms, helping to develop antibacterial and antiviral drugs to resist related diseases.
In pesticides, this substance also has important value. With its structural characteristics, pesticide products with high insecticidal and bactericidal properties can be developed. Because of its structure, it can precisely act on the specific physiological links of pests or pathogens, thereby effectively inhibiting their growth and reproduction, ensuring the healthy growth of crops and improving agricultural yield.
Furthermore, in the field of organic synthetic chemistry, it can be used as a synthetic building block with unique structures. Chemists can use various chemical reactions to construct more complex and special functional organic compounds, expand the boundaries of organic synthetic chemistry, and promote the research and development process of new materials and compounds. In short, this compound plays an indispensable role in many fields and is of great significance to the development of related industries.

In the synthesis of (2R, 3R) -3- (2,4-difluorophenyl) -3-methoxy-4- (1H-1,2,4-triazole-1-yl) butyl-2-yl acetate, there are three key steps.
The first is the nucleophilic substitution of halogenated aromatic hydrocarbons. The reaction of 2,4-difluorohalobenzene with an alcohol containing a specific substituent is heated in a suitable organic solvent such as N, N-dimethylformamide under alkali catalysis. The base can be selected from potassium carbonate or sodium hydride. The halogen atom of halobenzene reacts with the active hydrogen of the alcohol to form an ether bond, and an ether intermediate containing 2,4-difluorophenyl is obtained. In this step, the main points are to control the amount of alkali, reaction temperature and time. If the temperature is too high or the time is too long, side reactions will occur and the yield will decrease.
The second time is the introduction of triazole. With 1,2,4-triazole as raw material, in the presence of base, react with halogenated hydrocarbons or sulfonates containing suitable leaving groups. The base activates the triazole nitrogen atom to enhance its nucleophilicity, attack the carbon of halogenated hydrocarbons or sulfonates, form a C-N bond, and obtain an intermediate containing 1,2,4-triazole. The key to this step is the ratio of base to reactant, improper ratio, triazole self-coupling and other side reactions, which affect the purity and yield of the product.
The last is esterification reaction. The hydroxyl-containing intermediate is reacted with acetyl halide or acetic anhydride in an organic solvent such as dichloromethane in the presence of a catalyst such as 4-dimethylaminopyridine. The catalyst promotes the reaction, and the hydroxyl group forms an ester bond with the acyl group to obtain the target product (2R, 3R) -3- (2,4-difluorophenyl) -3-methoxy-4- (1H-1,2,4-triazole-1-yl) butyl-2-ylacetate. This step pays attention to the mild reaction conditions and prevents hydrolysis of ester groups or other side reactions.

There is now a product named (2R, 3R) -3- (2,4-difluorophenyl) -3-hydroxy-4- (1H-1,2,4-triazole-1-yl) butyl-2-ylacetate. Looking at its market prospects, this is an important compound in the field of fine chemicals.
At the end of pharmaceutical research and development, the synthesis of many antifungal drugs is often used as a key intermediate. The special structure of Gain 1,2,4-triazole group and fluorophenyl gives it excellent antifungal activity. At present, fungal infectious diseases are frequent, whether superficial infections or deep invasive infections, there is a strong demand for high-efficiency antifungal drugs. The drug research and development involved in this compound is in line with this trend, and the market demand is expected to rise steadily.
The agricultural field cannot be ignored either. With the rise of green agriculture, there is a growing demand for high-efficiency, low-toxicity and environmentally friendly pesticides. Compounds containing fluoride and triazole structures often exhibit good bactericidal and antibacterial effects, and can be used for the prevention and treatment of various crop diseases. Therefore, new pesticides developed on this basis are likely to gain a place in the future pesticide market.
Furthermore, the progress of chemical synthesis technology has laid the foundation for its large-scale production. Although the current synthesis process may have room for optimization, with the increase in scientific research investment, it is expected to achieve cost reduction and yield improvement. This will further enhance its market competitiveness and broaden its application scope.
In summary, (2R, 3R) -3- (2,4-difluorophenyl) -3-hydroxy-4- (1H-1,2,4-triazole-1-yl) butyl-2-yl acetate is used in the fields of medicine, agriculture and other fields. It has broad market prospects and great development potential. It is a category worthy of attention and investment in the chemical industry.

(2R, 3R) -3- (2,4-difluorophenyl) -3-hydroxy-4- (1H-1,2,4-triazole-1-yl) butyl-2-yl acetate is an organic compound, and its Quality Standards cover many aspects.
Looking at its properties, whether it is a specific appearance or a crystalline powder, with a white color and uniform texture, and no impurities visible to the naked eye, this is a preliminary characterization of its quality. In terms of purity, it is crucial to determine it by precise means such as high-performance liquid chromatography. The purity should reach a very high level, usually not less than 98% or even higher, to ensure the stability of its chemical properties and the reliability of the reaction results.
Regarding impurities, the content of various impurities is strictly limited. Such as organic impurities, which are generated from side reactions during the synthesis process, the content of each specific organic impurity shall not exceed 0.1%. The content of total organic impurities must also be controlled in a very low range to prevent it from adversely affecting the performance and safety of the product; inorganic impurities, such as residual metal ions, must also be strictly controlled to ensure product quality and safety.
Moisture content cannot be ignored. Generally, it is determined by the Karl Fischer method and should be maintained at a low level, usually no more than 0.5%. Excessive moisture or reactions such as hydrolysis of compounds will damage its structure and properties.
Melting point, as an important physical indicator, needs to be within a specific range, such as [specific melting point range], which can be accurately determined by melting point meter, which can reflect the purity and crystallization degree of the compound.
In addition, the residual solvent content also needs to follow relevant standards. All kinds of organic solvents used in the synthesis process, such as methanol, ethanol, etc., must be strictly controlled to prevent harm to the environment and users, and the residual amount of each solvent should meet the established safety standards.
These many Quality Standards are interrelated to ensure that (2R, 3R) -3- (2,4-difluorophenyl) -3-hydroxy-4- (1H-1,2,4-triazole-1-yl) butyl-2-yl acetate is of high quality and stable performance, which can meet the application needs of different fields.