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What is the chemical structure of (2R, 6R, 8R, 9As) -3-Oxooctahydro-2H-2, 6-Methanoquinolizin-8-Yl 1H-Indole-3-Carboxylate Methanesulfonate (1:1)
This is the name of the chemical substance. According to it, (2R, 6R, 8R, 9As) -3-oxo-octahydro-2H-2,6-methylenequinazine-8-yl 1H-indole-3-carboxylate methanesulfonate (1:1). To know its chemical structure, please listen to me in detail.
In the structure of this compound, the main part contains the skeleton of octahydro-2H-2,6-methylenequinazine, which has a carbonyl oxygen atom at position 3, that is, it presents a 3-oxo state. 1H-indole-3-carboxylic acid ester groups are connected at position 8, among which 1H-indole is a nitrogen-containing heterocyclic structure, and position 3 is connected to the main quinazine skeleton at position 8, and is connected by carboxylic acid ester bonds. Furthermore, the compound forms a 1:1 salt with methanesulfonic acid, that is, there is a methanesulfonate ion that interacts with the main cationic part to form this specific chemical structure. The overall structure is complex and delicate, and the various partial groups are connected to each other, giving this compound unique chemical properties and possible biological activities.
What are the main uses of (2R, 6R, 8R, 9As) -3-Oxooctahydro-2H-2, 6-Methanoquinolizin-8-Yl 1H-Indole-3-Carboxylate Methanesulfonate (1:1)
(2R, 6R, 8R, 9As) -3-oxoctahydro-2H-2,6-methylenaquinazine-8-yl 1H-indole-3-carboxylate methanesulfonate (1:1), this is a rather complex chemical substance. Its main uses are mostly in the field of medical research and development.
In the journey of medical exploration, such compounds may show the potential to treat specific diseases due to their unique chemical structures and properties. For example, in the study of neurological diseases, it may bring hope for the treatment of related diseases by targeting specific targets of the nervous system; in the field of anti-tumor drug development, it may also intervene in key links such as the proliferation and metastasis of tumor cells, becoming a powerful "weapon" against cancer.
In addition, in scientific research experiments, as an important reagent, it can help scientists to deeply explore specific physiological and pathological processes in organisms, providing key support for revealing the mysteries of life and disease mechanisms. However, due to its complex chemical structure, exquisite skills and rigorous processes are required in synthesis, purification and application in order to give full play to its potential effectiveness.
What are the physical properties of (2R, 6R, 8R, 9As) -3-Oxooctahydro-2H-2, 6-Methanoquinolizin-8-Yl 1H-Indole-3-Carboxylate Methanesulfonate (1:1)
(2R, 6R, 8R, 9As) -3-oxo-octahydro-2H-2,6-methylenequinazine-8-yl-1H-indole-3-carboxylate methanesulfonate (1:1) is an organic compound. It has specific physical properties.
This compound is in a solid state at room temperature, and its molecular structure is closely connected by covalent bonds between atoms to form a stable structure, resulting in a relatively high melting point. When it reaches a certain temperature, it melts into a liquid state. Its appearance may be white or off-white powder, due to the orderly arrangement of molecules and the scattering of light on its surface, presenting such visual effects.
In terms of solubility, because there are polar groups in the molecule, such as carboxyl groups and sulfonic acid groups, it may have certain solubility in polar solvents, such as water. However, because the molecule also contains large non-polar parts, such as indole rings, quinazine rings, etc., its solubility is not excellent. In organic solvents such as ethanol and acetone, the solubility is better than that of water. Because the polarity of the organic solvent matches the polarity of the compound molecule better, the intermolecular force is conducive to its dispersion and dissolution.
In addition, the compound may have a certain hygroscopicity. Because its polar groups can form hydrogen bonds with water molecules in the air, adsorb water molecules, and cause their mass to increase in humid environments.
As for the density, due to the relatively compact molecular structure and the large sum of the relative mass of atoms, the density may be relatively high, which is higher than that of common organic solvents. When storing, it is necessary to consider its physical properties and place it in a dry and cool place to prevent its properties from changing due to moisture absorption and temperature changes.
What is the synthesis method of (2R, 6R, 8R, 9As) -3-Oxooctahydro-2H-2, 6-Methanoquinolizin-8-Yl 1H-Indole-3-Carboxylate Methanesulfonate (1:1)
(The method of synthesis of this compound is quite complicated, and it needs to be achieved through a multi-step and delicate reaction. At the beginning, the appropriate starting materials need to be taken, and the fine ratio and ingenious treatment are required.)
First, the (2R, 6R, 8R, 9As) related cyclic structure material with a specific configuration needs to be purified and refined many times to ensure that its configuration is accurate. Then, it is condensed with 1H-indole-3-carboxylic acid under suitable reaction conditions. In this step, the reaction solvent, such as anhydrous organic solvents, such as dichloromethane, tetrahydrofuran, etc., needs to be carefully selected to create an environment conducive to the reaction. At the same time, it is necessary to add suitable catalysts, such as organic base catalysts, to promote the condensation between the two and form the key ester bond structure, to obtain (2R, 6R, 8R, 9As) -3-oxo-octahydro-2H-2,6-methylenaquinazine-8-yl 1H-indole-3-carboxylate intermediates.
Subsequently, this intermediate is reacted with methanesulfonic acid at a suitable temperature and reaction time. This step aims to form the final product of (2R, 6R, 8R, 9As) -3-oxo-octahydro-2H-2,6-methylenaquinazine-8-yl 1H-indole-3-carboxylate methanesulfonate (1:1). During the reaction, the reaction process needs to be closely monitored. The degree of reaction and the purity of the product can be observed by means of thin layer chromatography and liquid chromatography. After the reaction is completed, the target product with high purity can be obtained through multiple separation and purification processes such as extraction, washing, drying, column chromatography, etc. The entire synthesis process has strict requirements on the control of reaction conditions, the purity of raw materials, and the fineness of operation.
What is the market outlook for (2R, 6R, 8R, 9As) -3-Oxooctahydro-2H-2, 6-Methanoquinolizin-8-Yl 1H-Indole-3-Carboxylate Methanesulfonate (1:1)?
(2R, 6R, 8R, 9As) - 3-oxo-octahydro-2H-2,6-methylenequinazine-8-yl-1H-indole-3-carboxylate methanesulfonate (1:1), which is of great value to explore in the current market prospects.
Looking at its past, although there is no detailed history of its initial appearance, it has gradually emerged in the field of pharmaceutical chemistry. In recent years, medical research has advanced, and many studies have focused on the efficacy of new compounds on diseases. This compound has attracted the attention of scholars because of its unique chemical structure.
In the current market, with the increasing need to overcome complex diseases, this compound may be a key component in drug research and development, and it is expected to be made into a good drug against difficult diseases. It has shown active activity in the laboratory stage, paving the way for subsequent preclinical and clinical trials.
However, the market prospect is not smooth. Manufacturing costs are a major obstacle. Complex synthetic processes keep costs high. If large-scale production is to be carried out, methods to reduce costs need to be further explored. Furthermore, competition is fierce, innovation in the pharmaceutical industry is emerging, and similar compounds are also emerging in an endless stream. To stand out, quality and efficacy improvement are indispensable.
Despite challenges, opportunities coexist. With technological innovation and scientific research breakthroughs, costs may be reduced, and efficacy may be optimized. If we can seize the opportunity, this compound will definitely gain a place in the market, adding a bright color to the field of medicine and benefiting all living beings.
What is the chemical structure of (2R, 6R, 8R, 9As) -3-Oxooctahydro-2H-2, 6-Methanoquinolizin-8-Yl 1H-Indole-3-Carboxylate Methanesulfonate (1:1)
This is the chemical structure of (2R, 6R, 8R, 9As) -3-oxo-octahydro-2H-2,6-methylenequinazine-8-yl 1H-indole-3-carboxylate methanesulfonate (1:1). The structure of this compound is quite complex and is composed of many specific groups.
Its core part is the octahydro-2H-2,6-methylenequinazine structure. On the basis of this structure, 1H-indole-3-carboxylate groups are connected at 8 positions, and 3-oxo modifications are present. The methanesulfonate part is bound to the above main structure in a ratio of 1:1.
(2R, 6R, 8R, 9As) These symbols indicate the stereochemical configuration of a specific atom in a molecule. R stands for the clockwise configuration, and As may be a specific stereo labeling method. The uniqueness of this compound's structure determines that it may have specific physical, chemical and biological activities. Compounds with such complex structures may have unique uses in fields such as drug development, because of their structural characteristics or their ability to precisely bind to specific biological targets, showing specific pharmacological effects.
What are the main uses of (2R, 6R, 8R, 9As) -3-Oxooctahydro-2H-2, 6-Methanoquinolizin-8-Yl 1H-Indole-3-Carboxylate Methanesulfonate (1:1)
(2R, 6R, 8R, 9As) -3-oxoctahydro-2H-2,6-methylenequinazine-8-yl 1H-indole-3-carboxylate methanesulfonate (1:1), this substance is widely used. It can be used in the field of medicine or as an active pharmaceutical ingredient for the treatment of diseases. It interacts with human biological targets by virtue of its specific chemical structure to regulate physiological functions and relieve diseases. In the process of drug development, as a key compound, researchers can further explore its mechanism of action and pharmacokinetic properties, and then promote the birth of innovative drugs.
In the field of chemical synthesis, it is an important intermediate, providing the basis for organic synthesis chemists to build complex molecular structures. Through specific reactions, it can derive many compounds with unique properties and functions, expanding the boundaries of organic synthesis chemistry. In the field of materials science, or because of its unique physical and chemical properties, it can be used to develop new materials, such as materials with special optical, electrical or mechanical properties, injecting new vitality into the development of materials science. In short, this compound has important potential value in many fields and is of great significance to scientific progress and technological development.
What is the preparation method of (2R, 6R, 8R, 9As) -3-Oxooctahydro-2H-2, 6-Methanoquinolizin-8-Yl 1H-Indole-3-Carboxylate Methanesulfonate (1:1)
The preparation method of (2R, 6R, 8R, 9As) -3-oxo-octahydro-2H-2,6-methylenequinazine-8-yl 1H-indole-3-carboxylate methanesulfonate (1:1) is a delicate and rigorous process.
First, the raw materials need to be carefully prepared to ensure that (2R, 6R, 8R, 9As) -3-oxo-octahydro-2H-2,6-methylenequinazine-8-ol, 1H-indole-3-carboxylic acid and methanesulfonic acid have high purity, which is the basis for the preparation of high-quality products.
Then, in a suitable reaction vessel, (2R, 6R, 8R, 9As) -3-oxo-octahydro-2H-2,6-methylenaquinazine-8-ol and 1H-indole-3-carboxylic acid are combined with (2R, 6R, 8R, 9As) -3-oxo-octahydro-2H-2,6-methylenaquinazine-8-alcohol and 1H-indole-3-carboxylic acid. Under the help of a suitable condensing agent such as dicyclohexyl carbodiimide (DCC), the esterification reaction of the two is promoted in an inert gas protective atmosphere, an appropriate temperature (about 40-60 ° C) and a specific organic solvent (such as dichloromethane, etc
When the esterification reaction reaches the desired level, carefully remove the by-products of the condensation agent in the reaction system, such as filtration to remove dicyclohexylurea. Subsequently, methanesulfonic acid is introduced into the reaction system, and it is fully reacted with the formed esteride at a moderate temperature (about 20-30 ° C) to form the target product (2R, 6R, 8R, 9As) -3-oxoctahydro-2H-2,6-methylenaquinazine-8-yl 1H-indole-3-carboxylate methanesulfonate (1:1).
Finally, through a series of separation and purification steps, such as column chromatography, using silica gel as the stationary phase and a suitable eluent (such as a mixture of ethyl acetate and petroleum ether), the target product was precisely separated. After further purification by recrystallization, high purity (2R, 6R, 8R, 9As) -3-oxo-octahydro-2H-2,6-methylenaquinazine-8-yl 1H-indole-3-carboxylate methanesulfonate (1:1) was obtained.
How safe is (2R, 6R, 8R, 9As) -3-Oxooctahydro-2H-2, 6-Methanoquinolizin-8-Yl 1H-Indole-3-Carboxylate Methanesulfonate (1:1)
Nowadays, there are (2R, 6R, 8R, 9As) -3-oxo-octahydro-2H-2,6-methylenequinazine-8-yl 1H-indole-3-carboxylate methanesulfonate (1:1). Its safety is related to human life and cannot be ignored. The safety of this drug requires detailed examination of pharmacology and toxicology.
Pharmacologists, observe its effect on the human body and observe its effect on the viscera and meridians. If it can accurately act on the lesion without disturbing other places, it is good. In terms of toxicology, it is necessary to know whether it is toxic and how strong it is. Whether taking it will cause damage to the body, such as damaging the liver and kidneys, disturbing the mind and distracting the mind.
However, if you want to know the details, you must study it with scientific methods. Test it on animals first to observe its reaction. Observe the changes in its diet, movement, and spirit. If there are any abnormalities, you need to study the reasons in detail. Later, in human trials, select different groups and divide them into different doses to observe its effects and harms.
Only after many rigorous tests, and carefully examine its advantages and disadvantages, can we know the safety of (2R, 6R, 8R, 9As) -3-oxo-octahydro-2H-2,6-methylenaquinazine-8-yl 1H-indole-3-carboxylate methanesulfonate (1:1), in order to determine whether it can be used to treat diseases and save people and ensure the well-being of everyone.
What is the market outlook for (2R, 6R, 8R, 9As) -3-Oxooctahydro-2H-2, 6-Methanoquinolizin-8-Yl 1H-Indole-3-Carboxylate Methanesulfonate (1:1)?
(2R, 6R, 8R, 9As) -3-oxo-octahydro-2H-2,6-methylenaquinazine-8-yl 1H-indole-3-carboxylate methanesulfonate (1:1), this product has unique market prospects.
Looking at its characteristics, it is an organic compound with a specific configuration, composed of complex structures. Such compounds often have potential in the field of medicine, or can become a key ingredient in the development of innovative drugs.
In the past, the advent of many new compounds has triggered changes in medicine. For example, in ancient times, doctors searched for new herbs and stones in nature, and every new discovery brought hope to patients. Today's (2R, 6R, 8R, 9As) -3-oxo-octahydro-2H-2,6-methylenaquinazine-8-yl 1H-indole-3-carboxylate methanesulfonate (1:1), or the same.
In the current market, the demand for innovative drugs is increasing. Difficult diseases plague many patients. If this compound can be proven to have therapeutic effect by research, such as against specific neurological or cardiovascular diseases, its market space will be extremely broad. Pharmaceutical companies must compete and invest resources in R & D and production.
However, there are challenges. The compound structure is complex, and the synthesis may require high technology and high cost. And drug research and development must undergo strict tests to ensure safety and effectiveness before it can be listed. But over time, if it can break through the difficulties, it will shine like a new star in the pharmaceutical market, adding to the cause of human health, and the prospects are limitless.