What is the chemical structure of (2S) -3Beta- [2- (2-aminothiazole-4-yl) -2 (Z) - (carboxymethoxylamino) acetamide] -2Beta- (carbamoxymethyl) -4-oxo-azacyclobutane-1-sulfonate disodium salt?
(2S) -3 β - [2- (2-hydroxybenzene-4-yl) -2 (Z) - (carbonomethoxy hydroxy) ethyl] oxide-2 β - (hydroxyethoxy methyl) -4-oxo-heterocycloheptane-1-carboxylic acid diethyl ester, which is a rather complex organic compound. Its structure is formed by connecting many specific groups in a specific way.
Looking at its structure, the first chiral center (2S) is one of the key elements of the three-dimensional configuration of the fixed molecule. The 3 β position is connected with a long chain substituent, which contains a benzene ring, and the benzene ring has a hydroxyl group, and also contains a (carbonomethoxy hydroxylene) ethyl structure. There are functional groups such as carbon and oxygen double bonds in this structure, which have a profound impact on the properties of the compound. The 2 β position is connected with a (hydroxyethoxy methyl) group, which adds hydrophilicity to the molecule. The 4-oxo heterocyclic heptane is the core cyclic structure of the compound, and the oxygen atom in the ring plays a role in its stability and reactivity. The diethyl carboxylate attached to the 1-position gives the molecule specific reactive characteristics and physical properties.
Compounds with complex structures often have key applications in the fields of organic synthesis, medicinal chemistry, etc., or can be used as potential drug intermediates, chemically modified to obtain compounds with specific pharmacological activities, providing an important basis for pharmaceutical research and development.
What is the main use of (2S) -3Beta- [2- (2-aminothiazole-4-yl) -2 (Z) - (carboxymethoxylamino) acetamide] -2Beta- (carbamoxymethyl) -4-oxo-azacyclobutane-1-sulfonate disodium salt?
(2S) -3 β - [2- (2-hydroxyethoxy) -2 (Z) - (phosphoryloxyamino) ethyl] thio-2 β - (ethylthiomethoxy) -4-oxo-heterocyclic butane-1-carboxylic acid diphenyl ester, which is a rather complex organic compound. Its main use is described in the text according to the idea of "Tiangong Kaiji":
To view the structure of this compound, it may be useful in the field of medicine. Organic compounds are often the cornerstones of pharmaceutical creation, and their specific chemical structures or endow unique biological activities. For example, the heterocyclic butane structure is common in many drug molecules, or has the ability to regulate specific physiological processes in organisms.
It also contains functional groups such as phosphoryl hydroxylamino, or can interact with proteins, enzymes and other macromolecules in vivo. Or it can be used as an inhibitor of enzymes to intervene in specific biochemical reactions, such as enzymatic reactions of some key metabolic pathways, in order to regulate the physiological functions of organisms and have potential value in the treatment of diseases.
Furthermore, in the field of chemical synthesis, it may be an important intermediate. With this compound as a starting material, more complex organic molecules can be constructed by organic synthesis. Because of its polyfunctional groups, it can be derived through various reactions, such as substitution, addition, etc., to derive a series of compounds with different properties, providing possibilities for the research and development of new materials and the preparation of fine chemicals.
Although the "Tiangong Kaiwu" does not provide details of such compounds, it is inferred from the spirit of ancient artisans exploring material properties and uses. Under the development of today's science and technology, such complex organic compounds have important uses in fields such as medicine and chemical industry, which can benefit human health and life.
(2S) -3Beta- [2- (2-aminothiazole-4-yl) -2 (Z) - (carboxymethoxylamino) acetamide] -2Beta- (carbamoxymethyl) -4-oxoazaheterocyclobutane-1-sulfonate disodium salt What are the precautions in the use process
(2S) -3 β - [2- (2-hydroxyethoxy) -2 (Z) - (carboxyethoxy carbonyl) vinyl] -2 β - (hydroxyethoxy methyl) -4-oxo-heterocyclic butane-1-carboxylic acid di-tert-butyl ester, this is a complex organic compound. During use, many precautions must be kept in mind.
One is related to storage. Because of its chemical properties or relatively active, it should be stored in a cool, dry and well-ventilated place, away from fire and heat sources, to prevent it from deteriorating due to environmental factors such as temperature and humidity or causing dangerous reactions. If stored improperly, or the structure of the compound is changed, it will lose its due activity or produce harmful by-products.
Second, the operation specification is very critical. Be sure to wear appropriate protective equipment when operating, such as laboratory clothes, gloves and goggles. Due to its specific characteristics or unknown, direct contact or inhalation of its dust, vapor, or irritation and damage to the skin, eyes and respiratory tract. And the operation should be carried out in a well-ventilated place, such as a fume hood, to reduce the risk of harmful gas accumulation.
Third, the dosage needs to be precisely controlled. In view of the specific biological activity or pharmacological effect of the compound, dose deviation or deviation of experimental results will have a significant impact on subsequent research and application in application scenarios such as drug development. Or due to improper dosage, the desired effect cannot be achieved, or adverse reactions may be caused.
Fourth, waste disposal should not be underestimated. The used residue should not be discarded at will. It needs to be properly disposed of in accordance with relevant regulations and environmental protection requirements. Because it may contain special chemical structures and elements, it can be discharged at will or cause pollution to the environment, endangering the ecological balance. When following specific treatment procedures, ensure safety and environmental protection.
What are the pharmacological properties of (2S) -3Beta- [2- (2-aminothiazole-4-yl) -2 (Z) - (carboxymethoxylamino) acetamide] -2Beta- (carbamoxymethyl) -4-oxo-azaheterocyclobutane-1-sulfonate disodium salt
(2S) -3 β - [2- (2-hydroxyethoxy) -2 (Z) - (phosphoryloxycarboxylamino) ethyl] thio] -2 β - (ethylthiomethoxy) -4-oxo-heterocyclic butane-1-carboxylic acid diphenyl ester, this is a complex organic compound. Its pharmacological properties are quite critical, let me tell them one by one.
In terms of antibacterial activity, such heterocyclic butane structural compounds often have unique antibacterial properties. They may use specific mechanisms, such as inhibiting the synthesis of bacterial cell walls, to achieve antibacterial effect. Looking at the specific groups in their structure, or interact with key enzymes in bacteria, hinder the normal construction of cell walls, causing bacterial growth inhibition and even death.
Re-examine its pharmacokinetic properties. The fat solubility of the compound may be affected by groups such as benzyl ester, which in turn affects its absorption in the body. Those with good fat solubility may easily penetrate the biofilm and be well absorbed in the gastrointestinal tract. The distribution in the body, or selectively polymerize in specific tissues or organs due to the polar and non-polar parts of the structure. Metabolically, many groups in the structure may be metabolic check points, which are transformed by enzymes in the body to generate metabolites. Excretion routes, or through organs such as liver and kidney, are excreted in the form of prototypes or metabolites.
However, its pharmacological properties are also affected by many factors. Different bacteria have different sensitivities to it, or due to differences in bacterial cell wall structure and enzyme activity. And the stability of the compound in the body and external environment is also important. If the stability is not good, or it degrades before the drug effect is exerted. Its interaction with other drugs cannot be ignored, or it affects the absorption and metabolism of each other, and it needs to be carefully considered when using drugs.
What are the synthesis methods of (2S) -3Beta- [2- (2-aminothiazole-4-yl) -2 (Z) - (carboxymethoxylamino) acetamide] -2Beta- (carbamoxymethyl) -4-oxo-azaheterocyclobutane-1-sulfonate disodium salt?
The synthesis method of (2S) -3 β - [2- (2-hydroxyethoxy) -2 (Z) - (carboxyethoxy carbonyl) vinyl] -2 β - (hydroxyethoxy methoxy) -4-oxo-heterocyclic heptyl-1-enoic acid diethyl ester is a key investigation in the field of organic synthesis. Although the synthesis of this specific compound is not contained in "Tiangong Kaiji", the process idea contained in it can be used for reference.
To synthesize this compound, the selection of raw materials is quite important. Compounds with specific functional groups can be selected as starting materials, such as those containing hydroxyl groups, carboxyl groups, and alkenyl groups, just like those selected in the ancient method.
The reaction steps need to be step by step like the ancient process. First, the ester group structure is constructed by esterification reaction, which is the foundation for laying the skeleton of the compound, just like the foundation at the beginning of ancient creation. Under the action of catalysts, alcohol and carboxylic acid are heated and other conditions to promote esterification to form ester-containing intermediates.
Second, the olefin-related reaction is carried out. Using specific olefins as raw materials, with the help of addition and elimination reactions, the target olefin structure is introduced, just like the tenon-mortise fit of the parts in the ancient method, and it is precisely constructed.
Third, the steps of hydroxyl protection and deprotection are indispensable. The use of appropriate protective groups to protect the hydroxyl groups, and then deprotection after the specific reaction is completed to ensure that the hydroxyl groups play a role in the appropriate stage. This is the key to fine regulation, just like the clever treatment of material texture in the ancient method.
Fourth, the cyclization reaction builds a heterocyclic structure. Through intramolecular reactions, specific functional groups interact to form rings. This is the core step in shaping the unique structure of the target compound, just like the ancient method of shaping the unique shape of the artifact.
The control of reaction conditions is also the precise control of the temperature and season in the ancient method. Temperature needs to be precisely adjusted according to different reaction stages. Too high or too low will affect the reaction process and product purity. Catalyst selection and dosage are also crucial to accelerate the reaction and increase the yield. The reaction solvent also needs to be adapted to create a suitable reaction environment. In this way, many links are closely interlocked to achieve the effective synthesis of (2S) -3 β - [2- (2-hydroxyethoxy) -2 (Z) - (carboxethoxy carbonyl) vinyl] -2 β - (hydroxyethoxy methoxy) -4-oxo heterocyclic heptyl-1-enoic acid diethyl ester.