(2S,3S)-3-Amino-2-Methyl-4-Oxo-1-Adetidinesulfonic Acid (Azetidine)

The chemical structure of (2S, 3S) -3-amino-2-methyl-4-oxo-1-azacyclobutanesulfonic acid (azacyclobutane) is a very important research object in the field of organic chemistry. This compound has a unique spatial configuration and functional group combination.
Its core structure is azacyclobutane, which is a quaternary nitrogen-containing heterocyclic ring. At the 2nd and 3rd positions of the ring, there are specific substituents, respectively. The 2nd position is methyl, which is connected to the ring by a single bond. The introduction of methyl groups has an effect on the steric resistance and hydrophobicity of the molecule. The third position is the amino group, which has a certain alkalinity and can participate in many chemical reactions, such as salt formation with acids, nucleophilic substitution, etc.
And the fourth position is a carbonyl group (oxo). The existence of the carbonyl group endows the molecule with certain polarity and reactivity, and reactions such as nucleophilic addition can occur. Furthermore, the first position is connected with a sulfonic acid group, which is a strong acidic group, making the compound have good water solubility and has a significant impact on its chemical properties and biological activities.
The stereoconfiguration (2S, 3S) of this compound indicates that the atomic space arrangement of its 2 and 3 positions follows specific rules, and this stereochemical feature plays a key role in the reactions it participates in, especially when interacting with biomacromolecules. Due to the high stereoselectivity of many reactions in organisms, the specific stereoconfiguration can fit the activity check point of biomolecules, and then exert the corresponding physiological functions or pharmacological activities.

(2S, 3S) -3-amino-2-methyl-4-oxo-1-azacyclobutane sulfonic acid (azacyclobutane), having various physical properties. Its shape or solid, color or white, shape or powder state is determined by its molecular structure and arrangement.
Its melting point also has characteristics. The melting point is the critical temperature at which a substance changes from solid state to liquid state. Based on the intermolecular forces and lattice energy of this compound, the melting point may be in a specific temperature range, which is determined by factors such as intermolecular hydrogen bonds and van der Waals forces. The boiling point is related to the transition from liquefaction to gaseous state, and is also restricted by intermolecular forces.
In terms of solubility, it may have certain solubility characteristics in water. Due to the hydrophilicity of the internal molecular groups, which can form hydrogen bonds with water molecules, it may be partially soluble in water, but its solubility is not infinite due to the hydrophobicity of some structures. In organic solvents, such as ethanol and acetone, the solubility varies due to the interaction between the solvent and the solute molecule. In ethanol, or due to the principle of similar miscibility, it is in line with the partial structure of the compound, and has a certain solubility; in acetone, it also varies depending on the degree of matching of its intermolecular forces.
The density is related to the mass per unit volume. The density of this compound depends on its molecular weight and the degree of packing compactness, reflecting the relationship between its microstructure and macroscopic physical quantities. And its stability cannot be ignored. Under specific environmental conditions, the molecular structure may remain relatively stable, but it may change under extreme conditions such as high temperature, strong acid and alkali, or due to the breaking and rearrangement of chemical bonds in the molecule.

(2S, 3S) - 3-amino-2-methyl-4-oxo-1-azacyclobutane sulfonic acid (azacyclobutane) has a wide range of main application fields. In the field of pharmaceutical and chemical industry, this compound is often the key intermediate for the synthesis of various special drugs. Because of its unique structure and properties, it can help create drugs with specific physiological activities, such as antibacterial and antiviral drugs, for the treatment of various diseases, solve the suffering of the world, and contribute greatly.
In the field of organic synthesis, (2S, 3S) -3 -amino-2-methyl-4-oxo-1-azacyclobutane sulfonic acid can be used as an extremely important building block. With its unique spatial configuration and reactivity, chemists can ingeniously build complex organic molecular structures, expand the boundaries of organic synthesis, and pave the way for the development of new materials and new compounds.
In biochemical research, this substance is also of great value. Due to its structure or similarity to some key molecules in living organisms, it can be used to explore the mechanism of specific biochemical reactions in living organisms, help researchers gain insight into the mysteries of life, and play an important guiding role in the field of basic biological research. In short, (2S, 3S) -3-amino-2-methyl-4-oxo-1-azacyclobutane sulfonic acid plays a crucial role in many important fields, with broad prospects and far-reaching influence.

The synthesis of (2S, 3S) -3 -amino-2-methyl-4-oxo-1-azacyclobutanesulfonic acid (azacyclobutane) has attracted much attention in the field of organic synthetic chemistry. To form this substance, multiple paths can be taken.
First, by using a suitable enol derivative as the starting material, the asymmetric catalytic cyclization reaction can form an intracellular ring to construct the core skeleton of azacyclobutane. In this process, it is crucial to select a catalyst with high efficiency and high enantioselectivity. The activity and selectivity of the catalyst are directly related to the yield and stereochemical purity of the target product.
Furthermore, amino acid derivatives are used as the starting materials, and this purpose can also be achieved through multi-step transformation. First, the functional groups of amino acids are properly protected and activated, and then the structure of the target molecule is gradually built through reactions such as condensation and cyclization. During this period, the conditions of each step of the reaction need to be carefully regulated, such as reaction temperature, reaction time, and reagent dosage, which will have a significant impact on the reaction process and product quality.
In addition, transition metal catalysis strategies can also be used. Using the unique electronic structure and catalytic properties of transition metal catalysts, the precise construction of key chemical bonds such as carbon-nitrogen bonds and carbon-oxygen bonds can be achieved. This method often exhibits excellent regioselectivity and stereoselectivity, providing an effective way for the synthesis of high-purity (2S, 3S) -3-amino-2-methyl-4-oxo-1-azacyclobutanesulfonic acid.
However, all synthesis methods have advantages and disadvantages. In practical application, it is necessary to weigh and choose according to specific requirements, such as product purity, production cost, difficulty of reaction conditions, etc. In this way, the most suitable synthesis path can be found and the desired target product can be efficiently prepared.

(2S, 3S) - 3-amino-2-methyl-4-oxo-1-azacyclobutane sulfonic acid (azacyclobutane) must pay attention to many matters during storage and transportation.
First, temperature control is essential. The properties of this compound may change due to temperature fluctuations, and high temperature can easily cause it to decompose or deteriorate, so it should be stored in a cool place, usually 2-8 ° C, so that its chemical structure and activity can be kept stable. Temperature control measures should also be taken during transportation to avoid direct sunlight and hot topic environments to prevent damage to its quality.
Second, the influence of humidity should not be underestimated. Humid environment or cause reactions such as hydrolysis, which pose a threat to its purity and quality. When storing, a dry place should be selected, and a desiccant can be used to maintain the dry environment. The packaging should be tightly waterproof during transportation to prevent moisture from invading.
Third, the packaging material must be selected carefully. Materials with stable chemical properties and no reaction with the compound should be used. Containers such as glass or specific plastic materials can provide good protection. The packaging should be strong to prevent damage and leakage due to collision and extrusion during transportation.
Fourth, the compound may have certain toxicity and irritation, and protective measures are essential during operation. Storage areas should be well ventilated, and transportation personnel should also be equipped with appropriate protective equipment, such as gloves, goggles, and protective clothing, to avoid exposure to health hazards.
Finally, clear labeling is essential. Storage containers and transportation packages should be clearly labeled with information such as the name, nature, and hazard warnings of the compound, so that relevant personnel can clarify its characteristics, follow correct operating practices, and ensure safe storage and transportation.