As a leading ({[(2S,5R,6R)-6-{[(2R)-2-Amino-2-Phenylacetyl]Amino}-3,3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Hept-2-Yl]Carbonyl}Oxy)Methyl (2S,5R)-3,3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylate 4,4-Dioxide 4-Methylbenzenesulfonate (1:1) supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
({[ (2S, 5R, 6R) -6- {[ (2R) -2-amino-2-phenylacetyl] amino} -3,3-dimethyl-7-oxo-4-thio-1-azabicyclo [3.2.0] heptyl-2-yl] carbonyl} oxy) methyl (2S, 5R) -3,3-dimethyl-7-oxo-4-thio-1-azabicyclo [3.2.0] heptane-2-carboxylate 4,4-methylbenzenesulfonate (1:1) What is it?
This is an extremely complex expression related to organic compounds. It consists of many specific chemical groups and structural descriptions. ({[ ( 2S, 5R, 6R) -6- {[ (2R) -2-hydroxy-2-phenylacetamido] hydroxy} -3,3-dimethyl-7-oxo-4-thio-1-azabicyclo [3.2.0] heptyl-2-yl] amino} hydroxy) methyl (2S, 5R) -3,3-dimethyl-7-oxo-4-thio-1-azabicyclo [3.2.0] heptane-2-carboxylic acid 4,4-dioxide 4-methylbenzenesulfonate (1:1), which is chemically structured This complex structure endows it with unique chemical properties and potential biological activities. In the field of organic chemistry, compounds with such structures are often the focus of drug research and development. Due to their structural complexity, they may have specific pharmacological functions, such as interacting with specific targets in organisms to exhibit antibacterial, antiviral or other therapeutic effects. However, based on this structural information alone, it is difficult to determine its specific properties and uses. Further experimental studies are required, such as measuring its physical and chemical parameters and conducting biological activity tests, in order to clarify its actual value and application prospects in the fields of medicine, chemical industry, etc.
({[ (2S, 5R, 6R) -6- {[ (2R) -2-amino-2-phenylacetyl] amino} -3,3-dimethyl-7-oxo-4-thio-1-azabicyclo [3.2.0] heptyl-2-yl] carbonyl} oxy) methyl (2S, 5R) -3,3-dimethyl-7-oxo-4-thio-1-azabicyclo [3.2.0] heptane-2-carboxylate 4,4-methylbenzene sulfonate (1:1) What are the uses?
({[ (2S, 5R, 6R) -6- {[ (2R) -2-hydroxy-2-phenylacetyl] hydroxy} -3,3-dimethyl-7-oxo-4-thio-1-azabicyclo [3.2.0] heptyl-2-yl] amino} hydroxy) methyl (2S, 5R) -3,3-dimethyl-7-oxo-4-thio-1-azabicyclo [3.2.0] heptane-2-carboxylic acid 4,4-methylbenzenesulfonate (1:1), this substance is called ceftriaxone sodium, is the third generation of cephalosporins antibiotics. It has a wide range of uses and mainly shows important value in the following aspects:
In the field of antibacterial, it has strong antibacterial activity against both Gram-positive and negative bacteria. Gram-positive bacteria such as Streptococcus pneumoniae and Streptococcus pyogenes, as well as negative bacteria such as Escherichia coli and Klebsiella pneumoniae, are inhibited by it. Clinically, it is often used to treat respiratory tract infections, such as pneumonia, bronchitis and other diseases, which can effectively relieve symptoms and promote patient recovery; it is also used to treat urinary and genital tract infections. For urethritis, cystitis, etc., it can significantly reduce inflammation and restore patient health; it is also effective for abdominal and pelvic infections, which can control the spread of infection and save patients' lives.
Ceftriaxone sodium plays a key role in surgical prevention of infection. Before some clean-contaminated surgeries or contaminated surgeries, rational use of this drug can greatly reduce the chance of postoperative infection, ensure the smooth progress of the surgery, and help patients recover well after surgery.
In addition, for serious infections, such as sepsis, ceftriaxone sodium is often used as an important treatment drug. When used in combination with other drugs, it works synergistically to enhance the therapeutic effect and provide a strong guarantee for the life and health of patients. Because of its wide antimicrobial spectrum and exact efficacy, it plays a pivotal role in clinical anti-infective treatment.
({[ (2S, 5R, 6R) -6- {[ (2R) -2-amino-2-phenylacetyl] amino} -3,3-dimethyl-7-oxo-4-thio-1-azabicyclo [3.2.0] heptyl-2-yl] carbonyl} oxy) methyl (2S, 5R) -3,3-dimethyl-7-oxo-4-thio-1-azabicyclo [3.2.0] What are the chemical properties of heptane-2-carboxylate 4,4-methylbenzenesulfonate (1:1)?
({[ (2S, 5R, 6R) -6- {[ (2R) -2 -hydroxy-2 -phenylacetyl] hydroxy} -3,3 -dimethyl-7 -oxo-4 -thio-1 -azabicyclo [3.2.0] heptyl-2 -yl] amino} hydroxy) methyl + (2S, 5R) -3,3 -dimethyl-7 -oxo-4 -thio-1 -azabicyclo [3.2.0] heptanoic acid + 4,4 -dioxide + 4 -methylbenzenesulfonate + (1:1) The chemical substance has various properties.
The spatial structure of this compound is determined by the chiral center. The configurations such as (2S, 5R, 6R) and (2R) indicate that its atoms are specifically arranged in space and affect the interaction between molecules. It contains a number of special functional groups, such as hydroxyl, acetyl, methyl, oxo, sulfur and nitrogen heterocycles. Hydroxyl groups are hydrophilic and can participate in the formation of hydrogen bonds, which affects solubility and reactivity; methyl is alkyl, which increases fat solubility; oxygen groups make the compound oxidizable to a certain extent; sulfur and nitrogen heterocycles affect the distribution of electron clouds and reaction check points.
From the perspective of reaction, due to its structure containing a variety of activity check points, nucleophilic substitution and redox reactions can occur. In organic synthesis, hydroxyl groups and benzenesulfonate groups can be used as reaction check points for substitution reactions to form new chemical bonds. And their presence in a (1:1) ratio with other substances has specific significance in the measurement and balance of the reaction, or affects the direction of the reaction and the ratio of the product. And the compound fuses multiple structural fragments. In the field of medicinal chemistry, or due to unique structures and activity check points, it exhibits specific biological activities, such as binding to specific receptors to exert pharmacological effects.
({[ (2S, 5R, 6R) -6- {[ (2R) -2-amino-2-phenylacetyl] amino} -3,3-dimethyl-7-oxo-4-thio-1-azabicyclo [3.2.0] heptyl-2-yl] carbonyl} oxy) methyl (2S, 5R) -3,3-dimethyl-7-oxo-4-thio-1-azabicyclo [3.2.0] heptane-2-carboxylate 4,4-methylbenzenesulfonate (1:1) What is the production method?
To prepare ({[ (2S, 5R, 6R) -6- {[ (2R) -2-hydroxy-2-phenylacetyl] hydroxy} -3,3-dimethyl-7-oxo-4-thio-1-azabicyclo [3.2.0] heptyl-2-yl] amino} hydroxy) methyl (2S, 5R) -3,3-dimethyl-7-oxo-4-thio-1-azabicyclo [3.2.0] heptane-2-carboxylic acid 4, 4-dioxide 4-methylbenzenesulfonate (1:1) product, the method is as follows:
method in the past, or take the corresponding starting material first, and modify the functional group by multi-step reaction. For example, under suitable reaction conditions, or in an organic solvent, with a catalyst, nucleophilic substitution, oxidation and other reactions are carried out. The atoms or groups at specific positions are sequentially converted to form key intermediates.
Then the intermediate is used to carry out condensation reactions with compounds containing phenylacetyl groups and hydroxyl groups at appropriate temperatures and pH environments to construct the core structure of the target product. During this period, the reaction conditions may need to be fine-tuned to ensure that the configuration of each chiral center is correct.
After that, for the oxidation of the product structure, a suitable oxidizing agent is selected to oxidize the sulfur atom to the corresponding two oxides. And in another position, a methylbenzene sulfonylation reagent is used, and a methylbenzene sulfonate group is introduced to obtain the desired product.
When operating, it is necessary to observe the progress of each step of the reaction, and adjust the conditions in a timely manner according to the reaction phenomenon and monitoring data, such as temperature, time, and the proportion of reactants. And pay attention to the purity and configuration of the product. After each step, or separate and purify the method to remove impurities and ensure the quality of the product. In this way, the target product can be obtained and the required stoichiometric ratio can be achieved.
({[ (2S, 5R, 6R) -6- {[ (2R) -2-amino-2-phenylacetyl] amino} -3,3-dimethyl-7-oxo-4-thio-1-azabicyclo [3.2.0] heptyl-2-yl] carbonyl} oxy) methyl (2S, 5R) -3,3-dimethyl-7-oxo-4-thio-1-azabicyclo [3.2.0] heptane-2-carboxylate 4,4-methylbenzenesulfonate (1:1) What are the precautions during use?
({[ (2S, 5R, 6R) -6- {[ (2R) -2 -hydroxy-2-phenylacetyl] hydroxy} -3,3-dimethyl-7-oxo-4-thiobicyclo [3.2.0] heptyl-2-yl] amino} hydroxy) methyl + (2S, 5R) -3,3-dimethyl-7-oxo-4-thiobicyclo [3.2.0] heptanoic acid + 4,4-dioxide + 4 -Methylbenzenesulfonate + (1:1) There are many precautions to be paid attention to during use.
This is a mixed use of complex organic compounds, one of which needs to be carefully controlled. (1:1) The ratio is set, with a slight deviation, or the reaction is unbalanced, and the product is impure. If it is cooked fresh and the proportion of seasonings is inappropriate, the taste is not authentic.
Second, the chemical properties of each ingredient also need to be well-versed. ( 2S, 5R, 6R ) - ({[( 2S, 5R, 6R) -6- {[ (2R) -2 -hydroxy-2-phenylacetyl] hydroxy} -3,3-dimethyl-7-oxo-4-thio-1-azabicyclo [3.2.0] heptyl-2-yl] amino} hydroxy) methyl, etc., with specific activity and stability, in case of specific environments or substances, or adverse reactions. Such as flammable materials, in case of open flame will burn.
Third, the reaction environment is also crucial. Temperature, humidity, pH, etc., can affect the reaction process and product quality. If seeds germinate, they need to be suitable for temperature and humidity.
Fourth, the operation process must be standardized. From weighing, mixing to reaction monitoring, all need to be rigorous. A little carelessness, or cause experimental failure, or even cause safety accidents. If the boat is in the water, it will be covered if it is not careful.
Furthermore, the treatment after use should not be underestimated. Residual substances or products, or dangerous, need to be properly disposed of in accordance with regulations to avoid pollution of the environment or endangering safety. If the waste is discarded, it needs to be classified and compliant, and it should not be done at will.