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What is the chemical structure of (2S - Trans) -3 - Amino - 2 - Methyl - 4 - Oxoazetidine - 1 - Sulphonic Acid?
(2S-Trans) -3 -Amino-2-methyl-4-oxo-azacyclobutane-1-sulfonic acid, which is an organic compound. Its chemical structure is as follows:
Azacyclobutane is the core structure, which is a quaternary nitrogen-containing heterocycle. The nitrogen atom on the ring has specific electronic properties and reactivity, and plays a key role in many chemical reactions.
At the 3rd position of the ring, it is connected with an amino group (-NH2O). The amino group is basic and can participate in many nucleophilic reactions, such as nucleophilic addition or substitution reactions with acyl and carbonyl compounds, and plays an extraordinary role in the construction of complex compounds. At the
2 position, there is a methyl group (-CH 🥰), which is an alkyl group and is relatively stable. The presence of methyl groups changes the molecular space structure and electron cloud distribution, which affects the physical and chemical properties of compounds, such as solubility, boiling point, etc., and also affects the reaction selectivity. At the
4 position, there is an oxo group (= O), that is, a carbonyl group. The carbon-oxygen double bond of the carbonyl group gives it significant polarity. Carbon is electrophilic and vulnerable to attack by nucleophiles. It is a key reaction check point in organic synthesis, and can undergo many reactions such as reduction and addition. The sulfonic acid group at the
1 position (-SO 🥰 H) is highly acidic and can ionize hydrogen ions in water, making the compound have good water solubility. The strong electron-absorbing properties of sulfonic acid groups also have a profound impact on the distribution and reactivity of molecular electron clouds.
The unique structure of this compound makes it show potential application value in the fields of medicinal chemistry and organic synthetic chemistry. Or it can be used as an intermediate to synthesize drug molecules with specific biological activities. By modifying and modifying its structure, drugs with better performance can be obtained; in organic synthesis, its special structure can participate in the construction of more complex organic molecular skeletons.
What are the main uses of (2S - Trans) -3 - Amino - 2 - Methyl - 4 - Oxoazetidine - 1 - Sulphonic Acid?
(2S-trans) -3-amino-2-methyl-4-oxo-azacyclobutane-1-sulfonic acid has a wide range of uses. In the field of medicine, it is the key intermediate for the preparation of many β-lactam antibiotics. β-lactam antibiotics have strong bactericidal power, wide antibacterial spectrum and low toxicity, and play an important role in anti-infective treatment. ( 2S-trans) -3-amino-2-methyl-4-oxo-azobutane-1-sulfonic acid participates in the synthesis of such antibiotics, which can optimize their structure and improve their antibacterial activity, stability and pharmacokinetic properties.
In the field of organic synthesis, it is also an important building block. Due to its special structure and activity, it can be used to construct a variety of nitrogen-containing heterocyclic compounds, which are used in pesticides, dyes and functional materials. For example, in the creation of pesticides, compounds containing specific nitrogen heterocyclic structures or with unique biological activities can be developed into new and efficient pesticides.
In chemical production, it can be used as a catalyst or auxiliary agent. By virtue of its own acidic and structural characteristics, it can catalyze specific organic reactions, improve the reaction rate and yield; or in the process of material preparation, improve material properties, such as enhancing material stability, solubility, etc.
In summary, (2S - trans) - 3 - amino - 2 - methyl - 4 - oxo-azoheterocyclobutane - 1 - sulfonic acid has important uses in many fields such as medicine, organic synthesis and chemical industry, and has far-reaching impact on the development of related industries.
What is the method of production of (2S - Trans) -3 - Amino - 2 - Methyl - 4 - Oxoazetidine - 1 - Sulphonic Acid?
The production process of (2S-trans) -3-amino-2-methyl-4-oxo-azacyclobutane-1-sulfonic acid is a rather complicated process.
First, you can start from a specific starting material. Usually with a specific structure of nitrogen and sulfur-containing compounds as the starting point, through clever reaction sequences, the complex molecular structure is gradually constructed.
In the initial stage, or by a specific chemical transformation, the functional groups in the starting material are modified and activated. For example, using a specific reagent, the amino group of the nitrogen-containing part is properly protected to prevent it from participating in the side reaction without reason in the subsequent reaction and causing the product to be impure.
After that, the key cyclization reaction is carried out. This step requires precise regulation of the reaction conditions, such as temperature, reaction time, and catalyst dosage. If the temperature is too high, or the cyclization is excessive, unnecessary by-products are generated; if the temperature is too low, the reaction rate will be slow, which will affect the production efficiency. Careful selection of catalysts can effectively promote the smooth progress of the cyclization reaction, so that the molecule can smoothly form the core structure of azacyclobutane.
To complete the cyclization, the functional groups on the ring need to be further modified. For 2-methyl moiety, methyl groups may need to be introduced, and this process also requires careful selection of methylation reagents and reaction conditions to ensure that methyl groups are introduced into the target location accurately.
As for the construction of 4-oxo and 1-sulfonic acid groups, the same needs to be based on the delicate principles of organic synthesis. The 4-oxo moiety may be achieved by oxidation reaction, and a suitable oxidizing agent is selected to control the degree of oxidation to avoid excessive oxidation. The introduction of 1-sulfonic acid groups may require the use of sulfonic reagents to successfully connect the sulfonic acid groups to the specific positions of azobutane under suitable reaction conditions.
During the entire production process, multiple separation and purification operations are required. The impurities in the reaction mixture were removed by column chromatography, recrystallization and other classical methods to obtain high purity (2S-trans) -3-amino-2-methyl-4-oxo-azoobutane-1-sulfonic acid products. Each step of the reaction and operation needs to be carefully controlled to achieve the production goal of high efficiency and high purity.
What is the price range of (2S - Trans) -3 - Amino - 2 - Methyl - 4 - Oxoazetidine - 1 - Sulphonic Acid in the market?
I do not know the price range of (2S-trans) -3-amino-2-methyl-4-oxo-azacyclobutane-1-sulfonic acid in the market. The price of this compound may not fluctuate due to various factors such as use, purity, market supply and demand. For details, you can consult chemical raw material suppliers, chemical reagent distributors, or check on relevant chemical product trading platforms to get the exact price range in the near future. And the price of chemical products often changes from time to time, and the real-time price must be subject to the current market.
What are the safety and toxicity of (2S - Trans) -3 - Amino - 2 - Methyl - 4 - Oxoazetidine - 1 - Sulphonic Acid?
(2S-trans) -3-Amino-2-methyl-4-oxo-azacyclobutane-1-sulfonic acid is a critical issue related to safety and toxicity.
In terms of safety, it is necessary to carefully observe its performance in various environments and use scenarios. If it is used in industrial production, it will affect the operators in the production environment. Whether it will evaporate or leak during operation, and then threaten human health, needs to be further explored. If it is involved in its storage, its chemical stability should be considered, and whether it will undergo qualitative changes due to changes in environmental factors such as temperature and humidity, causing potential hazards.
In terms of toxicity, the first thing to do is to clarify its role in different biological systems. For mammals, it is necessary to study whether they will have toxic effects on the body through oral, percutaneous or inhalation routes, such as whether they will interfere with normal physiological functions, cause organ damage, or affect the nervous system, immune system, etc. For aquatic organisms, if they accidentally enter the aquatic environment, whether they will cause toxicity to aquatic organisms such as fish and algae, and disrupt the balance of aquatic ecology cannot be ignored.
In addition, from the perspective of chemical reactions, whether the substance will react violently with other common chemicals to produce more toxic substances is also a key consideration. Only through comprehensive and systematic research and analysis can we know the safety and toxicity of (2S-trans) -3-amino-2-methyl-4-oxo-azobutane-1-sulfonic acid with certainty, providing a solid basis for its rational use and proper disposal.