What is the main use of 3- (3-methyl-5-oxo-2,5-dihydro-1H-pyrazole-1-yl) benzenesulfonic acid?
3- (3-methyl-5-oxo-2,5-dihydro-1H-pyrrole-1-yl) benzoic acid, this compound has important uses in many fields.
In the field of medicinal chemistry, it is often used as a key intermediate in drug synthesis. Due to its specific chemical structure, it can participate in a variety of reactions to build drug molecules with specific biological activities. For example, it can be linked to other active groups through a series of chemical reactions to develop innovative drugs with anti-inflammatory, antibacterial or anti-tumor effects. This is because some parts of its structure can interact with specific targets in the organism to regulate physiological processes and achieve the purpose of treating diseases.
In the field of materials science, the compound also shows potential application value. For example, it can be introduced into the synthesis process of polymer materials to give the material special properties. With its unique electronic structure and spatial configuration, it may be able to enhance the stability, optical properties or electrical properties of the material. For example, if it is applied to organic optoelectronic materials, it may be possible to improve the charge transfer efficiency of the material and improve the performance of the material in devices such as Light Emitting Diodes and solar cells.
In the field of organic synthetic chemistry, it acts as an important synthetic building block. According to its structural characteristics, chemists can modify and derive its structure through various organic reactions, such as nucleophilic substitution reactions, coupling reactions, etc., to synthesize more complex and diverse organic compounds, providing a rich material basis and research direction for the development of organic synthetic chemistry.
What are the physical properties of 3- (3-methyl-5-oxo-2,5-dihydro-1H-pyrazole-1-yl) benzenesulfonic acid
3- (3-methyl-5-oxo-2,5-dihydro-1H-pyrrole-1-yl) benzoic acid is an organic compound with the following physical properties:
- ** Appearance and Properties **: Under normal conditions, it is mostly white to light yellow crystalline powder. If it is a fine powder, it has a fine texture. This morphology is related to its intermolecular forces and crystalline structure. The molecules are arranged in an orderly manner to form stable crystals, and the appearance shows such characteristics.
- ** Melting point and boiling point **: The melting point is in a specific temperature range, generally around [X] ° C. At this temperature, the molecules obtain enough energy to overcome the lattice energy, the lattice structure disintegrates, and the substance changes from solid to liquid. The boiling point is due to the stability of the compound and the intermolecular forces. At higher temperatures around [X] ° C, when the boiling point reaches the boiling point, the particles can overcome the attractive forces between the molecules in the liquid phase and become gaseous.
- ** Solubility **: In common organic solvents such as ethanol and acetone, it has certain solubility. Because these organic solvents and the compound can form intermolecular forces, such as hydrogen bonds, van der Waals forces, etc., to help them disperse and dissolve. However, the solubility in water is poor. Due to the mismatch between molecular polarity and water, it is difficult for water molecules to overcome the intermolecular forces of compounds to disperse uniformly.
- ** Density **: The density is about [X] g/cm ³, which reflects the mass of the substance per unit volume and is related to the molecular weight and the tightness of molecular accumulation. The molecular mass is large and the accumulation is tight, resulting in the corresponding density.
- ** Stability **: Stable at room temperature and pressure. Under specific conditions, such as high temperature, strong acid and alkali environment, due to the activity of certain chemical bonds in the molecule, the structure may change, and chemical reactions may occur, which affects its stability.
Is the chemical properties of 3- (3-methyl-5-oxo-2,5-dihydro-1H-pyrazole-1-yl) benzenesulfonic acid stable?
The chemical properties of 3- (3-methyl-5-oxo-2,5-dihydro-1H-pyrrole-1-yl) benzoic acid are quite stable. In this compound, the benzene ring structure endows it with certain conjugation stability. Although the substituents on the benzene ring have certain activity, under common mild conditions, the benzene ring itself is not prone to violent reactions such as ring opening.
methyl as a power supply group can affect the electron cloud density of the benzene ring, but this effect usually does not easily change the overall structure of the molecule. The heterocyclic structure of the 5-oxo-2,5-dihydro-1H-pyrrole-1-based part also has a certain stability, and the electron conjugation system in the ring makes this part maintain a relatively stable state.
In general environment, if there is no specific strong oxidizing agent, strong reducing agent or special reaction conditions, this compound can maintain its own structural integrity and chemical stability for a long time. Even in the common weak acid and weak base environment, the core part of the molecular structure is likely to remain intact, and only some substituents or marginal parts may have weak reactions, but it will not change the stability of the overall chemical properties.
What is the synthesis method of 3- (3-methyl-5-oxo-2,5-dihydro-1H-pyrazole-1-yl) benzenesulfonic acid
To prepare 3- (3-methyl-5-oxo-2,5-dihydro-1H-pyrazole-1-yl) benzoic acid, the following ancient method can be used.
First take appropriate starting materials, such as compounds containing methyl, oxo and pyrazole structures, and they should have activity checking points that can be modified and converted into target structures. Dissolve in suitable organic solvents, such as dichloromethane, N, N-dimethylformamide, etc., depending on the characteristics of the raw materials and reactions.
In the reaction system, slowly add specific reagents, such as alkali reagents, or nucleophilic and electrophilic reagents, to start the reaction. Bases, such as potassium carbonate, sodium hydroxide, etc., can adjust the pH of the reaction system and promote the reaction to proceed according to the expected path.
When reacting, pay attention to the control of temperature. Or low temperature to facilitate the selectivity of specific reaction steps, or temperature to increase the reaction rate. Temperature control devices such as water bath, oil bath or low temperature coolant can be used to stabilize the temperature of the reaction system within the required range.
During the reaction process, use thin layer chromatography (TLC) or other suitable analytical methods to check the progress of the reaction. When the raw materials are exhausted and the product is generated to the expected ratio, the reaction will be stopped.
Then, the post-treatment step is carried out. Extract with water and organic solvent to separate the product from the impurities. Compound column chromatography, select the appropriate silica gel column and eluent, such as petroleum ether and ethyl acetate in a specific ratio of eluent, further purify the product, remove its impurities, and obtain pure 3- (3-methyl-5-oxo-2,5-dihydro-1H-pyrazole-1-yl) benzoic acid.
This whole process needs to abide by the rules of chemical experiments, pay attention to safety, and prevent the harm of dangerous chemicals, so that the target product can be successfully prepared.
What is the price range of 3- (3-methyl-5-oxo-2,5-dihydro-1H-pyrazole-1-yl) benzenesulfonic acid in the market?
3- (3-methyl-5-oxo-2,5-dihydro-1H-pyrrole-1-yl) benzoic acid, this product is in the market price range, it is difficult to determine with certainty. However, to know its general outline, we must look at many reasons.
First, the source flow of materials. If the various raw materials required for its preparation are easy to obtain and affordable, and the supply is stable, the price of this product may be stable and slightly lower. However, if the raw materials are rare, difficult to purchase, or their sources are subject to changes in weather, geographical location, and personnel, the price must be high.
Second, the technique of preparation. If the preparation method is simple, consumes less energy, and has a considerable yield, the cost can be reduced, and the price will follow. If the preparation process is complicated, requiring rare utensils, special conditions, or multiple purification and refining, resulting in low yield, the cost will increase greatly and the price will be high.
Third, the supply and demand of the city. If there are few applicants in the market, and the supply exceeds the demand, the merchant will sell the goods, or reduce the price in order to sell. On the contrary, if the product is urgently needed by the industry and is in short supply, the price will rise.
Fourth, the bundle of regulations. Pharmaceutical, chemical and other industries are strictly regulated. If this product must follow onerous regulations in production, circulation and use, resulting in increased costs, its price will also be affected.
To sum up the above reasons, the price of 3- (3-methyl-5-oxo-2,5-dihydro-1H-pyrrole-1-yl) benzoic acid in the market may vary from time to time and from place to place, ranging from a few yuan per gram to several hundred yuan per gram, but this is only an idea. The actual price shall be subject to the real-time market.
