Products

3-(4-Morpholino)Propane Sulfonic Acid

Lingxian Chemical

Specifications

HS Code

650709

Chemical Formula C7H15NO4S
Molar Mass 209.26 g/mol
Appearance White to off - white crystalline powder
Solubility Soluble in water
Ph Range For Buffer 6.5 - 7.9
Pka Value 7.2 at 25°C
Melting Point 274 - 276°C
Density N/A (usually measured for liquid form, this is solid)
Stability Stable under normal conditions
Hazard Class Non - hazardous for usual handling
Packing & Storage
Packing 500g of 3-(4-Morpholino)Propane Sulfonic Acid in a sealed, chemical - resistant bag.
Storage Store 3-(4-Morpholino)Propane Sulfonic Acid in a cool, dry place away from heat and direct sunlight. Keep it in a tightly sealed container to prevent moisture absorption and contamination. Avoid storing near reactive chemicals. This ensures its stability and integrity for accurate use in various applications like buffer preparation.
Shipping 3-(4-Morpholino)Propane Sulfonic Acid is shipped in well - sealed containers, often in a dry state. Packaging ensures protection from moisture and physical damage during transit to maintain chemical integrity.
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3-(4-Morpholino)Propane Sulfonic Acid
General Information
Historical Development
Those who have tasted the goodness of ancient times and worked hard for the subtlety of things. Today there is a thing named 3 - (4 - Morpholino) Propane Sulfonic Acid, which has its origin. In the beginning, the sages explored at the end of the day, wanting to understand its nature. As the years went on, the workers studied untiringly. Or in the secret room, observe its changes; or in the classics, seek its origin. From ignorance to understanding, from the shallow to the deep. Everyone is united, and they study the nature of the material, analyze its structure, and observe its reaction. Finally, this material is known to the world, and its use is gradually widened. It is useful in medicine and work. The development of things is like a long river rushing, from the beginning of the trickle to the present day, thanks to the diligence of the public, in order to obtain today's grand scene, for future generations, but also for the chemical industry add color.
Product Overview
Today there is a product called 3- (4 - Morpholino) Propane Sulfonic Acid. This is a product studied in chemistry, which is stable and widely used. Its shape is either powder or crystalline, with a white and pure color.
In the field of biochemical experiments, this product is often used as a buffer, which can stabilize the acid and base of the solution and ensure the smooth flow of the reaction. Because of its unique structure and specific groups, it has this ability. It plays a significant role in protein, enzyme and other studies, and can protect the activity of biological molecules, so that the experimental results are accurate.
Looking at this chemical, the preparation needs to follow a delicate method and control the conditions to maintain purity. When storing, it is also necessary to be cautious, avoid moisture and light, and store it in a suitable temperature place, so that it can be stored for a long time without changing its nature, for scientific research purposes, to help explore the way.
Physical & Chemical Properties
There is now a thing called 3- (4 - Morpholino) Propane Sulfonic Acid. Its physical and chemical properties are worth studying. This substance can be viewed in its shape, or in a specific state, or with a certain color and smell. Regarding its solubility, in some solvents, it may be soluble or insoluble, which is related to the characteristics of its molecular structure. Its chemical activity is also the key. Under specific conditions, it may react with other substances to form new substances. The reaction mechanism is determined by the arrangement and bonding of atoms in its molecules. The exploration of such various physical and chemical properties can provide a solid theoretical basis for its application in various fields.
Technical Specifications & Labeling
Today there is a product called 3- (4-Morpholino) Propane Sulfonic Acid. Its process specifications and identification (product parameters) are the key. The process specifications of this product need to be carefully selected raw materials, the proportion of all materials must be accurate, and the preparation process should be orderly and methodical. Every step is related to quality. In terms of identification, the name needs to be clear and correct, and the marked parameters such as purity and properties must be in line with the authenticity. In this way, the product process specifications and identification are essential to become a sophisticated product.
Preparation Method
To make 3 - (4 - Morpholino) Propane Sulfonic Acid, the required raw materials and preparation method are as follows: First, take an appropriate amount of 4 - Morpholinoethanol and 1,3 - propane sultone as raw materials. The preparation process involves placing the two in a reaction vessel in a certain ratio. The reaction steps are as follows. Control the reaction temperature in a suitable range and stir evenly to make the two fully react. The reaction process needs to be carefully controlled, and the reaction phenomenon should be observed to determine the degree of reaction.
Its catalytic mechanism, a suitable catalyst can be selected to accelerate the reaction process and improve the product generation efficiency. The amount of catalyst needs to be precisely regulated to avoid affecting the purity of the product. In this way, 3 - (4 - Morpholino) Propane Sulfonic Acid can be obtained through a series of operations. All aspects of the preparation process need to be strictly treated to ensure the quality of the product.
Chemical Reactions & Modifications
The properties of substances are related to reaction and change. Today there is 3- (4 - Morpholino) Propane Sulfonic Acid, which is in the field of chemistry, reaction and denaturation are quite important.
This compound has a unique structure, and the atoms are connected in an orderly manner. In the reaction, the functional groups show their functions. Amino and sulfonic acid groups each have their own characteristics. Under suitable conditions, either acid-base neutralization or nucleophilic substitution is involved.
As for denaturation, it may change due to temperature or solvent. Under high temperature, the molecules are active, the reaction is accelerated, and the structure may change. Different solvents have different solubility, which also affects the reaction path.
Looking at its chemical behavior, it can be used in synthesis, analysis and other fields. Only by observing its reaction and variability can we make good use of it and contribute to the progress of chemical research and engineering.
Synonyms & Product Names
Today there is a substance called 3- (4 - Morpholino) Propane Sulfonic Acid. This substance has a wide range of uses in the field of biochemistry. Its aliases are also numerous, all of which are related to its essence.
This compound is often a key material in various experiments and studies. It can be used to aid in the separation of proteins or for buffering, and its effect is significant. Although its different names have different expressions, they all refer to the same thing.
When we study this substance, we should study its various names in detail to make it clear that it refers to the same thing. In this way, on the road of biochemical exploration, it is possible to travel unimpeded, use its power to break the problem, explore the mystery of the subtle, and contribute to the study of biochemistry, so as to achieve a grand cause.
Safety & Operational Standards
3- (4 -Morpholinyl) propanesulfonic acid is related to safety and operating standards, and cannot be ignored.
If you want to make or use this compound, the first priority is safety. Although its properties are not fully known, when operating, you must strictly follow the procedures. In a well-ventilated place, avoid its air, fog, dust and contact with people's body, skin and eyes. If you are not protected, you must not approach it. Wear appropriate protective clothing, goggles or masks to prevent accidents.
Operating specifications are also the gist. When weighing, the utensils must be accurate and the dosage should be accurate. When dissolving, stir well to quickly melt in the solvent. The temperature and time of the reaction should be controlled to an appropriate degree, according to the established process, step by step, and do not rush.
If there is any accident, touch it or inhale it, quickly move to a fresh place in the air, and remove the stained clothes. If the skin is stained, wash it with a lot of water and soap; if it enters the eye, rinse it with water for a long time and seek medical attention.
After use, dispose of it properly. Do not discard it in the environment at will, and place it in categories according to relevant regulations for professional disposal. In this way, Fang Quan Security, also abide by the normal track of operation, is essential in the research and production of chemistry.
Application Area
3 - (4 - Morpholino) Propane Sulfonic Acid is also a chemical substance. It is used in the field of biochemistry, and it is often used in the field of biochemistry. Biochemical performance, need to be determined in the environment, this can be made of acid, to maintain the properties of the solution, so that the reverse process can be carried out.
In the research and development, it also has its function. It can be used as a material for the production of materials, to help the production of materials, to promote their proper release, and to increase the effectiveness. And its nature is peaceful, less harmful to living organisms.
The production of materials, such as the production of materials, can improve the properties of liquid solution, so that the product is uniform, dense, and the product is improved. In other words, this transformed thing has its uses in many domains, and its benefits are not limited.
Research & Development
Recently, I have been studying 3- (4 - Morpholino) Propane Sulfonic Acid in my research, and the research has deepened. At the beginning, explore its properties, observe its physical characteristics, such as color state, degree of melting and boiling, and know that it is stable. Then study its chemical properties, and know its changes between reactions.
Today's research focuses on expanding its use. Think about the field of biochemistry, or can be used as a buffer agent, stabilize the acid and base of the environment, and ensure the smooth reaction. Also think about the creation of materials, use its properties to adjust the quality of materials, and hope to obtain new energy.
However, the road to research is full of thorns. The method of preparation still needs to be carefully studied, and the technique of efficiency and purity needs to be pursued. At the time of application, it also encounters obstacles, and it is necessary to explore the conditions in detail so that the effect can be fully developed. I will make unremitting efforts to achieve remarkable results in the research and development of this object, adding new colors to Xuelin.
Toxicity Research
Toxicity of 3 - (4 - Morpholino) Propane Sulfonic Acid. Observe its chemical structure, containing specific groups, or have potential effects on biological systems. Take various organisms as subjects to observe their reaction after exposure. At the beginning of the experiment with microorganisms, observe its growth and metabolism changes. Then take the plant test to see its germination and development. Later, use animal research to explore its physiological function and behavior differences. After many experiments, record data in detail and analyze its toxic effects. Or acute toxicity, resulting in poor rapid appearance of the subject; or chronic toxicity, long-term exposure to symptoms. It is necessary to clarify the nature of its toxicity, for its use and prevention, to provide solid evidence.
Future Prospects
I have a thing now, called "3- (4-Morpholino) Propane Sulfonic Acid". Looking at this thing, although it is in the present, its future prospects are limitless. This material is unique, and it is expected to shine in many fields. It can be used for delicate biochemical experiments to pave the way for exploring the mysteries of life; or it can emerge in the development of materials and endow materials with novelty. Its potential is like a treasure hidden in the clouds. It is waiting for my generation of scientific researchers to study tirelessly, clear the clouds, see the future glory, open a new chapter, lead scientific research to a new realm, and leave endless benefits for future generations.
Frequently Asked Questions
What are the main uses of 3- (4-Morpholino) Propane Sulfonic Acid?
3- (4-morpholinyl) propanesulfonic acid, often referred to as MOPS in English, has a wide range of uses in the field of biochemical and molecular biology experiments.
First, it plays a significant role in the construction of buffer systems. Many biochemical reactions in organisms are extremely sensitive to pH value, and small changes may affect the reaction process and protein activity. MOPS has good buffering ability, which can maintain the stability of solution pH in a specific pH range. For example, in RNA-related experiments, RNA is easily degraded by environmental pH, and MOPS buffer stabilizes pH at 7.0-8.0, providing a stable environment for RNA to ensure its structural and functional integrity.
Second, it is indispensable for protein research. Protein isolation, purification and activity analysis all need to be suitable for pH environment. MOPS buffer creates a stable environment to prevent protein denaturation and aggregation. In electrophoresis experiments, the MOPS buffer system ensures that proteins are effectively separated according to charge and size, which helps to analyze protein purity and molecular weight.
Third, the field of cell culture also plays an important role. Cell growth requires strict environmental requirements, and pH is a key factor. MOPS buffer regulates the pH of cell culture medium, providing a stable living environment for cells, promoting cell growth and proliferation, and maintaining normal physiological functions of cells.
Fourth, it plays a key role in enzymatic reactions. The activity of enzymes depends on specific pH conditions, and MOPS buffer provides a suitable pH to maintain high enzyme activity. In some enzymatic reactions that require specific pH initiation and maintenance, MOPS ensures the smooth progress of the reaction, providing a guarantee for the study of enzyme kinetics and metabolic pathways.
In which fields is 3- (4-Morpholino) Propane Sulfonic Acid widely used?
3 - (4 - morpholinyl) propanesulfonic acid, often referred to as MOPS, is widely used in many fields such as biochemistry and molecular biology.
In biological buffer systems, MOPS plays a key role. Because it has a moderate pKa value of about 7.2, it can effectively maintain the stability of the pH of the system near the physiological pH. In cell culture, cell growth is extremely sensitive to pH. MOPS can create a suitable pH environment to ensure normal cell growth and metabolism. For example, in animal cell culture, small changes in pH may affect cell activity and function. MOPS buffer can ensure pH stability within a suitable range.
In molecular biology experiments, such as nucleic acid electrophoresis, protein analysis, etc., MOPS is also quite commonly used. During nucleic acid electrophoresis, the appropriate pH environment has a significant impact on the migration and separation of nucleic acids. The MOPS buffer system can provide a stable pH, allowing nucleic acids to achieve good separation according to their own size and charge characteristics, which is convenient for subsequent analysis and detection.
In the field of enzymatic reaction research, the activities of many enzymes are greatly affected by pH, and MOPS buffer can regulate the pH of the reaction system, so that the enzymes are in the best active state. For example, some key enzymes involved in the metabolic pathway have the highest activity at a specific pH, and MOPS can create and maintain this pH, which can help study the mechanism and kinetic properties of enzymatic reactions.
In addition, in the early stage of drug development in vitro experiments, MOPS is used to simulate the physiological environment, evaluate drug stability, solubility, and interactions with biomacromolecules, providing key data support for drug development.
What are the Physical and Chemical Properties of 3- (4-Morpholino) Propane Sulfonic Acid
3 - (4 - morpholinyl) propanesulfonic acid, its physical and chemical properties are as follows:
This substance is mostly white crystalline powder in appearance, stable in properties, easy to store and use. In terms of solubility, it is easily soluble in water to form a clear and transparent solution. Because its molecular structure contains sulfonic acid groups, it is acidic, and can ionize hydrogen ions in aqueous solution, making the solution acidic.
The melting point of this substance is quite fixed, and through accurate measurement, it is a specific numerical range. This property is of great significance for its purity identification. And it has good thermal stability. It will not decompose rapidly or undergo chemical changes due to heating within a certain temperature range, ensuring that it can function normally in many experimental or production scenarios that require heating.
In addition, it plays a significant role in the field of organic synthesis. It is often used as a buffer to regulate the pH of the reaction system, maintain the stability of the reaction environment, ensure the smooth progress of the reaction in the expected direction, and improve the reaction efficiency and product purity. In biochemical research, because it has little impact on bioactive substances and can effectively simulate the acid-base environment in organisms, it is widely used in buffer system configuration, laying a good environmental foundation for biomacromolecular research, cell culture and other experiments.
What is the Synthesis Method of 3- (4-Morpholino) Propane Sulfonic Acid
3 - (4 - Morpholino) Propane Sulfonic Acid is 3- (4 - morpholino) propanesulfonic acid, often abbreviated as MOPS, which is a biological buffer. The synthesis method is as follows:
The starting materials are morpholine and 1,3 - propane sulfonate lactone. Both are easy to obtain and relatively stable in nature. Dissolve an appropriate amount of morpholine in an organic solvent, such as anhydrous acetonitrile, stir well to create a mild reaction environment. The boiling point of acetonitrile is moderate and the solubility is good, which can make the morpholine evenly disperse.
Slowly add 1,3 - propane sulfonate lactone to the acetonitrile solution of morpholine under stirring. The dripping speed needs to be strictly controlled to prevent the reaction from being too violent. 1,3-propanesulfonolactone has high activity and can undergo nucleophilic substitution reaction with morpholine.
After the dropwise addition is completed, the temperature of the reaction system is maintained in a certain range, usually at 40-60 ° C, and the stirring is continued for several hours. Moderate heating can accelerate the reaction and ensure that the reaction is sufficient. During the reaction, the reaction process can be closely monitored. The raw material consumption and product formation can be observed by means of thin layer chromatography (TLC).
When the reaction is over, reduce the temperature of the reaction system to room temperature. Subsequently, the acetonitrile solvent is removed by reduced pressure distillation to obtain a crude product.
The crude product is purified by column chromatography or recrystallization. Column chromatography can separate impurities according to the polarity difference of the compound; recrystallization selects a suitable solvent, such as ethanol-water mixed solvent, and uses the solubility difference to purify the product, and finally obtains high-purity 3- (4-morpholinyl) propanesulfonic acid.
What is the market price of 3- (4-Morpholino) Propane Sulfonic Acid?
The price of 3- (4 -morpholinyl) propanesulfonic acid in today's market is difficult to determine. Due to different businesses, different quality products, and different purchase quantities, its price fluctuates.
Looking at the market conditions of the past, if you buy it from ordinary chemical shops and retail it in small quantities, the price per gram may be between a few yuan and tens of yuan. The cover can affect its price due to its preparation process, raw material cost, and degree of purification.
If the quantity is large and you ask directly from the manufacturer, the price may be slightly reduced. When wholesale, if the batch reaches more than kilograms, the price per kilogram may be in the range of hundreds of yuan. However, this is not a definite number. Due to market supply and demand, seasonal changes, the price is also variable.
In different places, the price varies due to the difference in transportation costs and taxes. In prosperous cities, prices may be high; in remote places, or due to logistics inconvenience, prices may vary.
In addition, those with excellent quality and high purity must be more expensive than those with ordinary quality. In order to know its exact market value, it is necessary to consult various suppliers in detail, compare the quotations of various parties, and consider comprehensively before obtaining a rough estimate.