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What are the main uses of 3-Amino-5-Chloro-4-Hydroxybenzenesulphonic Acid?
3-Amino-5-chloro-4-hydroxybenzenesulfonic acid has a wide range of uses. In the dye industry, it is a key intermediate. It can be converted into many colorful dyes through specific chemical reactions, which are used in the dyeing process of fabrics, leather and other materials to make products show colorful colors. Due to its structural characteristics, it can be combined with dyes, and the resulting dyes are bright in color and have good fastness.
In the field of medicine, it also has important uses. Due to its unique chemical structure, it can be used as a starting material or intermediate for the synthesis of certain drugs. With the help of chemical modification and reaction, compounds with specific pharmacological activities can be prepared for the treatment and prevention of diseases.
In the pigment industry, it also plays an important role. After specific processing, it can be made into high-quality pigments, which are used in the production of inks, coatings and other products. Such pigments have high color stability and can give products good visual effect and durability.
Furthermore, in the synthesis of some fine chemical products, 3-amino-5-chloro-4-hydroxybenzenesulfonic acid is often used as an important raw material to help synthesize various fine chemicals with special properties to meet the needs of different industries and life.
What are the physical properties of 3-Amino-5-Chloro-4-Hydroxybenzenesulphonic Acid?
3-Amino-5-chloro-4-hydroxybenzenesulfonic acid, the properties of this substance are particularly important, and it is related to the performance of many applications. Its color state is mostly white to beige crystalline powder, which is fine and uniform, and has a high quality.
In terms of solubility, it is soluble in water, which makes it easy to disperse and participate in the reaction or application of aqueous systems. However, in organic solvents, such as ethanol, ether, etc., its solubility is quite limited, only slightly soluble or insoluble. This property makes it necessary to carefully consider in the operation of organic phases. The melting point of
is also a key physical property. It is about a specific temperature range. This temperature is the critical point for its solid-state to liquid-state transformation, which has a great impact on its thermal processing and molding processes. If it is heated higher than the melting point, its morphology changes or its properties change, so the temperature control during processing needs to be accurate.
In terms of stability, it is still stable under normal conditions and can be moderately preserved in general environments. In case of extreme chemical environments such as strong oxidizing agents and strong acids and alkalis, its structure may change, triggering chemical reactions and causing damage to its performance. And under special conditions such as light, high temperature, and high humidity for a long time, it may gradually deteriorate and reduce its stability. Acidity is its important property. It contains a sulfonic acid group and is acidic to a certain extent. It can be used as an acidic catalyst in some chemical reactions or participate in acid-base neutralization reactions. It is used in chemical synthesis, drug preparation, and other fields.
What are the synthetic methods of 3-Amino-5-Chloro-4-Hydroxybenzenesulphonic Acid?
The synthesis method of 3-amino-5-chloro-4-hydroxybenzenesulfonic acid has been explored by many parties throughout the ages. There are three methods, which are described in detail below.
First, 3-nitro-5-chloro-4-hydroxybenzenesulfonic acid is used as the starting material. This raw material can be obtained by reducing the method. The reduction method often uses iron powder and hydrochloric acid as reducing agents and reacts at an appropriate temperature and time. The reaction mechanism is that iron powder interacts with hydrochloric acid to generate new hydrogen. This hydrogen has strong reductivity and reduces the nitro group to an amino group to obtain 3-amino-5-chloro-4-hydroxybenzenesulfonic acid. This process requires fine temperature control. If the temperature is too high, it may cause side reactions to increase, which will affect the purity and yield of the product.
Second, 5-chloro-4-hydroxybenzenesulfonic acid is used as the starting material. After nitration reaction, nitro is introduced to obtain 3-nitro-5-chloro-4-hydroxybenzenesulfonic acid, and then reduction is carried out. Finally, the target product can be obtained. In the nitrification reaction, suitable nitrifying reagents should be selected, such as mixed acids (a mixture of nitric acid and sulfuric acid). The ratio of mixed acids, reaction temperature and time all have a great impact on the reaction. Improper proportions or temperature discomfort can cause the introduction of nitro groups to deviate from expectations, or generate by-products such as polynitro compounds. The reduction step is similar to the former, and caution is also required.
Third, use a suitable phenolic compound as the starting material. First protect the phenolic hydroxyl group to prevent it from being affected in the subsequent reaction. Then, introduce chlorine atoms through the halogenation reaction, and then gradually build the target molecular structure through nitrification, reduction and other steps. The method of protecting phenolic hydroxyl groups is often used by etherification or esterification. A suitable halogenating agent can be selected for the halogenation reaction, and the position and quantity of chlorine atoms introduced can be precisely controlled according to the reaction conditions and substrate activity. The subsequent nitrification and reduction steps also need to be carefully adjusted according to the main points of the previous method to obtain pure 3-amino-5-chloro-4-hydroxybenzenesulfonic acid.
The above methods have their own advantages and disadvantages, and need to be carefully selected according to the specific experimental conditions, availability of raw materials and requirements for product quality.
3-Amino-5-Chloro-4-Hydroxybenzenesulphonic precautions when storing Acid
3-Amino-5-chloro-4-hydroxybenzenesulfonic acid, this is a chemical substance. When storing, many things need to be paid attention to.
Bear the brunt, the control of temperature and humidity is crucial. This substance should be stored in a cool and dry place. If the ambient temperature is too high, it may cause chemical reactions to occur and cause its properties to change; if the humidity is too high, it is easy to make it damp, which in turn affects the purity and quality. If it is hot and humid in summer, you need to be extra cautious, or use dehumidification equipment and air conditioners to adjust the temperature and humidity.
Furthermore, light should not be ignored. It should be placed in a dark place to avoid direct sunlight. Under light, some chemical bonds may break, causing decomposition reactions, damaging its chemical structure, causing it to fail or deteriorate. Therefore, the storage container or warehouse should be made of light-shielding material.
This substance may be corrosive and toxic to a certain extent. When storing, it must be isolated from other items, especially flammable, explosive and easily neutralized objects. It should be stored separately in a specific area and clearly marked to prevent accidental touch and misuse. At the same time, the storage place should be well ventilated to prevent the accumulation of harmful gases.
During storage, it should also be checked regularly. Check whether the packaging is damaged and whether the appearance of the substance changes, such as color and shape changes. If there is any abnormality, it needs to be dealt with in a timely manner to prevent the problem from worsening and ensure that it is always in good storage condition to maintain the stability of its chemical properties.
3-Amino-5-Chloro-4-Hydroxybenzenesulphonic Acid market price
3-Amino-5-chloro-4-hydroxybenzenesulfonic acid, the price of inter-market is related to various reasons. In the past, as described in "Tiangong Kaiwu", the price of various products was determined by factors such as origin, supply and demand, and season. The same is true for this acid. The price of its price is judged first by the raw materials. If the raw materials are abundant and easy to purchase and cheap, the cost of making this acid will decrease, and the price will also be lower. On the contrary, the raw materials are rare and expensive, and it is not easy to obtain, and its price will be high.
Second, the complexity and simplicity of the process is also the main reason. If the production method is refined and cooked, saves labor and time, and consumes less energy, the acid produced will be priced or close to the people. However, if the process is complicated, requires multiple processes, takes a long time and consumes a lot of manpower and material resources, the price should be high.
Furthermore, the state of market supply and demand has a huge impact on the price. If there are many users of this acid, the demand outweighs the supply, and the merchants will raise their prices when they see benefits. When the supply exceeds the demand, the merchants may reduce the price in order to sell their goods.
In addition, the distance of the origin is also related. The origin is close to the user, the freight is saved, and the price may be appropriate. If the origin is remote, long-distance transshipment is expensive, and the cost is not expensive, this fee is also spread in the price.
Moreover, the quality of the second order can also make the price different. High-quality acid, suitable for high-end applications, and the price must be higher than ordinary ones.
In summary, the market price of 3-amino-5-chloro-4-hydroxybenzenesulfonic acid is not determined uniformly, but is the result of various factors. To know its exact price, it is necessary to consider the current situation in detail.