3-Cyano-6-(2-Hydroxy-2-Methylpropoxy)Pyrazolo[1,5-A]Pyridin-4-Yl Trifluoromethanesulfonate

This is the chemical structure analysis of 3-cyano-6- (2-hydroxy-2-methylpropoxy) pyrazolo [1,5-a] pyridine-4-yl trifluoromethanesulfonate. Looking at its name, it can be seen that this compound is composed of several parts spliced together.
First, "3-cyano", that is, in the No. 3 position of the mother nucleus of pyrazolo [1,5-a] pyridine, is connected with a cyano (-CN) group. This cyano group is active in nature and is often a key check point in many reactions. It can participate in nucleophilic substitution, addition and other reactions, and endow specific chemical activities to compounds.
"6- (2-hydroxy-2-methylpropoxy) ", which means that it is connected to 2-hydroxy-2-methylpropoxy at the 6th position of the parent nucleus. This part contains hydroxy (-OH), which is hydrophilic and can participate in the formation of hydrogen bonds, which affects the physical and chemical properties of compounds. The existence of 2-methyl changes the molecular space structure and also plays a role in its solubility and reactivity.
"Pyrazolo [1,5-a] pyridine" is the parent nuclear structure, which is formed by fusing the pyrazole ring with the pyridine ring. This fused ring structure endows the compound with a unique electron cloud distribution and spatial configuration, laying the foundation for its chemical properties.
"4-yltrifluoromethanesulfonate" refers to the connection of trifluoromethanesulfonate (-OTf, -OSO -2 CF) groups at the No. 4 position of the parent nucleus. Trifluoromethanesulfonate is an excellent leaving group. In organic synthesis, this check point is often prone to nucleophilic substitution reactions, which is conducive to the construction of new chemical bonds and the synthesis of more complex compounds.
In summary, the structure of 3-cyano-6- (2-hydroxy-2-methylpropoxy) pyrazolo [1,5-a] pyridine-4-yl trifluoromethanesulfonate is synergistic with each other, endowing the compound with unique chemical properties and reactivity, which is of great research and application value in the field of organic synthetic chemistry.

3-Cyano-6- (2-hydroxy-2-methylpropoxy) pyrazolo [1,5-a] pyridine-4-yl trifluoromethanesulfonate, which has a wide range of uses. In the field of medicinal chemistry, it is often a key intermediate, helping to create new drugs. Due to the special cyano, hydroxyl-containing alkoxy and pyrazolopyridine structures in the molecule, it has unique chemical activities and pharmacological properties. It can be synthesized by organic synthesis, through various reaction pathways, and spliced with other compounds to construct a complex molecular structure with specific biological activities, which can be used to develop drugs for the treatment of various diseases.
In the field of materials science, it also has potential application value. Because of its trifluoromethanesulfonate group, this group imparts specific electrical, optical or thermal properties to the compound. For example, in the field of organic optoelectronic materials, it may be introduced into the material structure through rational molecular design and modification to optimize the charge transport performance, light absorption and emission characteristics of the material, so that it can be applied to optoelectronic devices such as organic Light Emitting Diodes (OLEDs) and solar cells to improve device performance and efficiency.
Furthermore, in organic synthesis chemistry, it can participate in various organic reactions as a reaction substrate or catalyst. Due to the existence of different functional groups in the molecule, it can trigger reactions such as nucleophilic substitution, electrophilic addition, and cyclization, providing an effective way for the synthesis of complex and novel organic compounds, and assisting organic synthesis chemists to expand the synthesis methodology and create more unique organic molecules.

The preparation of 3-cyano-6- (2-hydroxy-2-methylpropoxy) pyrazolo [1,5-a] pyridine-4-trifluoromethanesulfonate is an important task in organic synthesis. The first thing to do is to prepare starting materials, such as pyrazolopyridine compounds with specific substituents, which may be prepared from common basic materials such as pyridine and pyrazole through a multi-step reaction.
To introduce cyano groups, common cyanide reagents, such as potassium cyanide, sodium cyanide, etc., react with raw materials in the presence of suitable solvents and catalysts. The reaction conditions need to be carefully controlled, such as temperature, pH, etc., to ensure that the cyanyl group is accurately connected to the target check point.
As for the introduction of 2-hydroxy-2-methylpropoxy, 2-hydroxy-2-methylpropanol can be selected as the reagent, and an appropriate base is used as the catalyst to cause the alcohol hydroxyl group to undergo nucleophilic substitution with a suitable leaving group in the raw material, such as a halogen atom or a sulfonate group. This step also needs to pay attention to the reaction conditions to avoid side reactions.
After the key functional groups are connected, the last step is the introduction of trifluoromethanesulfonate groups. Trifluoromethanesulfonyl chloride and other reagents are commonly used to react with the aforementioned products in an alkaline environment to achieve the final product 3-cyano-6- (2-hydroxy-2-methylpropoxy) pyrazolo [1,5-a] pyridine-4-yl trifluoromethanesulfonate synthesis. After each step of the reaction, it needs to be separated and purified, such as column chromatography, recrystallization, etc., to ensure the purity of the product for subsequent reactions or applications.

3-Cyano-6- (2-hydroxy-2-methylpropoxy) pyrazolo [1,5-a] pyridine-4-yl trifluoromethanesulfonate, this is an organic compound. Its physical properties are related to many aspects, and let me elaborate.
First of all, the appearance of this compound is usually in solid form. As for the color, it is mostly white to off-white powder with fine texture. Looking at its morphology, the powder is conducive to its uniform dispersion in the reaction system, full contact with other reactants, and then promote the reaction.
Besides solubility, this compound exhibits a certain solubility in organic solvents. Common alcoholic solvents such as methanol and ethanol can dissolve this substance because they contain hydroxyl groups and can form hydrogen bonds with some groups in the compound. In halogenated hydrocarbon solvents such as dichloromethane and chloroform, although the force is not as strong as the hydrogen bond, it can also be dissolved to a certain extent by virtue of the van der Waals force between molecules. However, its solubility in water is poor, because most of the hydrophobic groups in the molecular structure interact weakly with water molecules.
Melting point is also an important physical property. Experiments have determined that its melting point is in a specific temperature range, which is the result of the combined action of intermolecular forces and crystal structures. The determination of the melting point can not only be used to identify the purity of the compound, but also is of great benefit to the study of its stability under different temperature conditions.
In addition, the density of this compound is moderate, and the density reflects the mass per unit volume of the substance, which is of great significance for the precise control of the amount of material in its practical application.
The above physical properties are of great significance in chemical production, drug research and development and other fields. Chemical production can choose the appropriate reaction solvent and separation method according to the solubility; in drug development, its appearance, melting point and other properties affect the molding and stability of drug formulations. From this perspective, it is crucial to clarify the physical properties of this compound.

What you are asking about is the market price range of 3-cyano-6- (2-hydroxy-2-methylpropoxy) pyrazolo [1,5-a] pyridine-4-yltrifluoromethanesulfonate. However, this product is not a common and universal product that I know of. The market price varies due to many factors, such as quality, supply and demand, manufacturing costs, place of transaction, and time of sale.
If you want to know the price, you can go to the place where the chemical raw materials are traded, consult the merchants, or visit the online platform where the professional chemical products are traded, and observe the listed price, or visit the brokerage and trader of chemical products to ask about the market. However, I cannot describe the price range, because there is a lack of many necessary information. Only by visiting the relevant places and visiting multiple parties can we obtain a more accurate price range.