What are the chemical properties of 3- (Cyclohexylamino) -Propane Sulfonic Acid?
3- (cyclohexylamino) propanesulfonic acid is a useful chemical substance. Its properties are white crystalline powder, which has good solubility in water and is slightly soluble in organic solvents.
In terms of its chemical properties, this substance has a certain degree of acidity. Sulfonic acid groups (-SOH) are the main source of its acidity. In aqueous solutions, sulfonic acid groups can be partially ionized, releasing hydrogen ions (H 🥰), making the solution acidic. This acidic property makes it an acidic catalyst in many chemical reactions, catalyzing the progress of specific organic reactions.
In terms of stability, under normal conditions, 3- (cyclohexylamino) propanesulfonic acid is quite stable and can be stored for a long time without easy deterioration. However, when it encounters strong oxidizing agents, strong acids or strong bases, its structure may be affected and chemical reactions cause structural changes.
In addition, in its molecular structure, cyclohexyl provides a certain hydrophobicity, while sulfonic acid groups and amino groups impart hydrophilicity. This special structure makes the substance surface active, and in some systems, it may reduce surface tension, showing effects such as emulsification and dispersion. In the field of biochemistry, because it has good buffering properties, can adjust the pH value of the solution, and maintain the stability of the pH of the system, it is often used as a buffer for biochemical experiments to create a suitable environment for the activity and stability of biomolecules.
3- (Cyclohexylamino) -Propane Sulfonic Acid is used in what fields?
3 - (cyclohexylamino) propanesulfonic acid, often known by its English abbreviation CAPS. This substance has extraordinary uses in many fields such as biochemistry, molecular biology, and medicine.
In the field of biochemical research, because of its unique acid-base buffering properties, it can effectively maintain the pH stability of the solution in a specific pH range, just like a strong barrier to resist the interference of external factors on the pH of the solution. Many enzymatic reactions are extremely sensitive to the pH of the environment. If there is a slight deviation, the activity of the enzyme will be affected, and CAPS can create a suitable pH environment to ensure the smooth and orderly progress of the enzymatic reaction, just like paving a smooth way for the enzymatic reaction.
In molecular biology experiments, key operations such as the separation and purification of nucleic acids and proteins are inseparable from it. For example, in protein electrophoresis experiments, it acts as an important component of the buffer system to ensure the stability of the electric field environment during the electrophoresis process, so that proteins can be accurately separated according to their own charge and molecular weight differences, just like a fine screen, distinguishing proteins one by one according to their characteristics.
In the field of medicine, it also plays an important role. In the drug development process, it can be used to simulate the human physiological environment, help study the dissolution, absorption, metabolism and other processes of drugs in the body, and light up the light for the creation of new drugs. In some pharmaceutical preparations, it can adjust the pH of the preparation, enhance the stability and solubility of the drug, as if to put on a solid "armor" for the drug to ensure that the drug effect is fully exerted.
In addition, in clinical diagnostic reagents, with its excellent buffering capacity, it provides a stable environment for detection reactions, improves detection accuracy and reliability, and acts as a reliable guard to protect the authenticity and accuracy of detection results.
3 - (cyclohexylamino) propanesulfonic acid Although it is a small chemical substance, it plays a key role in many important fields and is of great significance to scientific research and human health.
What are the synthesis methods of 3- (Cyclohexylamino) -Propane Sulfonic Acid?
The common methods for preparing 3 - (cyclohexylamino) propanesulfonic acid are as follows.
First, 3-chloropropanesulfonic acid and cyclohexylamine are used as raw materials. In an appropriate reaction vessel, 3-chloropropanesulfonic acid is placed, and then cyclohexylamine is slowly added. This reaction needs to pay attention to the reaction temperature, which is often controlled in a moderate range. If the temperature is too high, it may cause side reactions to breed and affect the purity of the product. The two are nucleophilic substitution reaction, the chlorine atom is replaced by the amino group of cyclohexylamine, and then 3 - (cyclohexylamino) propanesulfonic acid is obtained. After the reaction is completed, it needs to be separated and purified, such as recrystallization, to remove the unre
Second, 3-bromopropanesulfonic acid can react with cyclohexylamine. This reaction mechanism is similar to the former, both of which are nucleophilic substitution. The bromine atom of 3-bromopropanesulfonic acid has high activity and is easy to react with the amino group of cyclohexylamine. During the reaction process, the choice of solvent is very critical, and the appropriate solvent can promote the reaction and improve the reaction rate and yield. After the reaction, extraction, distillation and other means are also required to achieve the purpose of purification.
Furthermore, acrylate and cyclohexylamine are used as the starting materials, and the addition reaction is first carried out to generate a nitrogen-containing intermediate. Then the intermediate is hydrolyzed and sulfonated to obtain 3- (cyclohexylamino) propanesulfonic acid. This route is a bit complicated, but common raw materials can be used, and the reaction conditions of each step are relatively mild. Each step of the reaction requires precise control of the reaction conditions, such as reaction time, temperature, reactant ratio, etc., in order to make the reaction proceed in the expected direction and improve the quality and yield of the product. Each method has its own advantages and disadvantages. In actual preparation, it is necessary to choose carefully according to the availability of raw materials, cost, product purity requirements and many other factors.
What are the reactions of 3- (Cyclohexylamino) -Propane Sulfonic Acid with other compounds?
3- (cyclohexylamino) -propanesulfonic acid, often referred to as CAPS, is a zwitterionic buffer frequently used in biochemical research. It has specific acid-base properties and can play a buffering effect in a specific pH range to ensure the stability of the pH value of the solution.
When it comes to the reaction of this compound with other compounds, the first to bear the brunt is the acid-base neutralization reaction. CAPS has weakly acidic and weakly basic groups, which can neutralize with strong acids or bases. If it encounters a strong acid such as hydrochloric acid, its basic cyclohexylamino part will combine with hydrogen ions to form corresponding salts; if it reacts with a strong base such as sodium hydroxide, the sulfonic acid group will interact with hydroxide ions to form salts, and water will be formed in the process. These reactions are often used to adjust the pH value of the solution and maintain the acid-base balance of the system.
Secondly, nucleophilic substitution reactions are also common. In view of the presence of sulfonic acid groups, the carbon atoms in the CAPS molecule can act as electrophilic centers to attract nucleophiles. For example, if there are nucleophiles containing amino or hydroxyl groups, it is possible to replace the groups on the carbon atoms attached to the sulfonic acid groups to form new compounds. This reaction is of great significance in the field of organic synthesis, which can be used to form new chemical bonds and synthesize organic molecules with special structures and functions.
Furthermore, the condensation reaction should not be underestimated. When CAPS coexists with compounds containing carboxyl or aldehyde groups, under suitable conditions, condensation reactions can occur. Take carboxyl-containing compounds as an example, the two will remove a molecule of water and form amide or ester bonds. This process often requires the help of catalysts to speed up the reaction rate. This reaction is widely used in the synthesis of peptides and polyesters, which helps to construct complex macromolecular structures.
In addition, coordination reactions are also worthy of attention. The nitrogen and oxygen atoms in CAPS molecules can provide lone pairs of electrons to form coordination bonds with metal ions to form complexes. The formation of these complexes may change the chemical and physical properties of metal ions, and may have potential applications in catalysis, materials science and other fields. For example, some metal-CAPS complexes may serve as catalysts to improve the efficiency and selectivity of specific chemical reactions.
3- (Cyclohexylamino) -What is the market price of Propane Sulfonic Acid?
3 - (cyclohexylamino) propanesulfonic acid, what is the price of this product in the market? I have checked all the books, and its price varies for many reasons.
First, it is about purity. If the purity is extremely high, it is almost flawless, and it is suitable for high-end experiments, fine chemicals and other fields, the price will be very high. For example, high-purity samples used in top scientific research projects can cost tens of gold per gram, or even hundreds of gold, because of their strict control of impurities, cumbersome purification processes, and a lot of manpower and material resources.
Second, the amount also has an impact. If the purchase volume is large, such as required for industrial production, the merchant may make a profit due to economies of scale, and the price per unit may be slightly reduced. On the contrary, only a small amount is used for experimental exploration, and the unit price may be higher.
Third, the supply and demand of the city is also the key. If there is a peak demand season and the supply is limited, the price will rise. On the contrary, if the supply exceeds the demand, the merchant may reduce the price in order to promote sales.
Furthermore, the price varies depending on the manufacturer. Well-known large factories have high prices due to their brand reputation and excellent production technology; while small factories produce, although the price is low, the quality may be difficult to match that of large factories.
In summary, if you want to know the exact price, you should consult the supplier in detail, compare its quotation, and take into account the quality and quantity needs, in order to know its price.
