3-Ethyl 5-Methyl 2-[(2-Aminoethoxy)Methyl]-4-(2-Chlorophenyl)-6-Methyl-1,4-Dihydropyridine-3,5-Dicarboxylate Benzenesulfonate (1:1)

This is the chemical structure analysis of 3-ethyl-5-methyl-2- [ (2-aminoethoxy) methyl] -4- (2-chlorophenyl) -6-methyl-1,4-dihydropyridine-3,5-dicarboxylate benzenesulfonate (1:1).
Looking at its name, it can be seen that this compound is composed of dihydropyridine derivatives and benzenesulfonate in a 1:1 ratio.
Preface dihydropyridine moiety: 1,4-dihydropyridine is used as the parent nucleus, ethyl is connected at the 3rd position, methyl is connected at the 5th position, methylene is connected at the 2nd position (2-aminoethoxy), 4 is connected at the 4th position (2-chlorophenyl), methyl is also connected at the 6th position, and dicarboxylate is at the 3rd and 5th positions. This structure gives it a specific spatial configuration and electronic effect, which affects its chemical and biological activities.
Looking at the benzenesulfonate part again, it binds to the above-mentioned dihydropyridine derivatives at a 1:1 ratio. In the benzene sulfonic acid radical group, the benzene ring has a conjugated system, and the sulfonic acid group - SO
As a whole, this chemical structure determines its physical and chemical properties, such as solubility, stability, etc., and also affects its absorption, distribution, metabolism and excretion in vivo, which is related to its pharmacological activity and medicinal value.

This substance is called 3-ethyl-5-methyl-2 - [ (2-aminoethoxy) methyl] -4 - (2-chlorophenyl) -6-methyl-1,4-dihydropyridine-3,5-dicarboxylate benzenesulfonate (1:1), which is widely used in the field of medicine. Its main uses are as follows:
First, it is of great significance in the prevention and treatment of cardiovascular diseases. It belongs to 1,4-dihydropyridine compounds, which are mostly calcium channel blockers. Calcium channel blockers can selectively block calcium ions from entering cells through calcium channels on the cell membrane, thereby relaxing vascular smooth muscles, reducing peripheral vascular resistance, and achieving the effect of lowering blood pressure. Therefore, this substance can be used in the treatment of hypertension, help patients stabilize blood pressure, and reduce the risk of various complications caused by hypertension. In addition, its vasodilation effect can increase coronary blood flow, relieve myocardial ischemia, and improve angina symptoms, bringing good news to patients with coronary heart disease.
Second, it has made a name for itself in the field of neuroprotection. Calcium ions play a key role in the physiological and pathological processes of the nervous system. When the nervous system is damaged, a large amount of calcium ions outside the cell are infused, which will trigger a series of pathological reactions, resulting in nerve cell damage. This substance acts as a calcium channel blocker, or can adjust the concentration of intracellular calcium ions, reduce nerve cell damage caused by calcium ion overload, and has potential neuroprotective effects on ischemic brain injury and neurodegenerative diseases, opening up new paths for the treatment of neurological diseases.
Third, it plays an active role in improving microcirculation. Because of its vasodilation function, it can dilate microvessels, increase microcirculation blood flow, and improve blood perfusion in tissues and organs. In the treatment of some microcirculation disorders, such as diabetic microangiopathy and Raynaud's disease, it can improve microcirculation, relieve disease progression, and improve patients' quality of life.

This is a rather complex organic compound, its full name is 3-ethyl + 5-methyl + 2 - [ (2-aminoethoxy) methyl] - 4 - (2-chlorophenyl) - 6-methyl-1,4-dihydropyridine-3,5-dicarboxylate benzenesulfonate (1:1).
Its physical properties have certain characteristics. Looking at its morphology, it is often solid or crystalline. This is due to the intermolecular force of the compound, which causes it to form a regularly arranged lattice structure.
When it comes to solubility, it may have a certain solubility in organic solvents, such as ethanol, acetone, etc. This is due to the interaction between the polarity of the organic solvent and the partial groups of the compound, which can overcome the partial intermolecular forces and disperse the compound. However, the solubility in water may be limited due to the many hydrophobic groups in the molecular structure, which reduces its ability to form hydrogen bonds with water molecules.
As for the melting point, this compound may have a specific melting point range. Due to the regularity of the molecular structure and the magnitude of the intermolecular forces, during the heating process, when a certain temperature is reached, the lattice structure is destroyed and the solid state is transformed into a liquid state. This melting point range is of great significance for its identification and purity judgment.
In addition, its density is also one of the physical properties. Due to the determination of molecular composition and structure, the mass per unit volume is relatively stable, and the density can be used as a characteristic parameter of the compound, which may have reference value in the process of substance identification and separation.

This is a method of chemical synthesis, which involves 3-ethyl + 5-methyl + 2 - [ (2-aminoethoxy) methyl] - 4 - (2-chlorophenyl) - 6-methyl-1,4-dihydropyridine-3,5-dicarboxylate benzenesulfonate (1:1). The first step in its synthesis is to use suitable starting materials, such as pyridine derivatives with specific substituents, or related nitrogenous, oxygenated, and halogenated benzene compounds as groups.
The starting materials are carefully screened and pretreated, and then put into the reaction system. In the initial stage of the reaction, or by condensation reaction, the aminoethoxy-containing part is connected to a specific position on the pyridine ring. In this step, suitable catalysts and reaction conditions need to be selected, such as under mild heating and alkaline environment, to promote the nucleophilic substitution reaction to occur smoothly, so as to construct the [ (2-aminoethoxy) methyl] structure in the pyridine ring.
Then, for the introduction of other substituents on the pyridine ring, such as ethyl and methyl, it can be achieved by alkylation reaction. Select a suitable alkylation reagent, and react with the pyridine derivative at the appropriate reaction temperature and solvent system to precisely locate the substitution check point to ensure the correctness of the product structure.
As for the connection of the 4- (2-chlorophenyl) part, or through the aromatic nucleophilic substitution reaction, under specific conditions, 2-chlorobenzene can be combined with the designated position on the pyridine ring to improve the substituent structure around the pyridine ring.
After the main structure of the pyridine derivative is constructed, the next step will focus on the formation of the dicarboxylate structure. Or an esterification reaction can be used to react the corresponding carboxylic acid with an alcohol under acid catalysis to form a 3,5-dicarboxylate structure. This process requires controlling the reaction temperature and time to ensure the efficient and accurate formation of ester bonds.
Finally, in order to obtain the benzenesulfonate (1:1) of the target product, the synthesized 3,5-dicarboxylate pyridine derivative is mixed with benzenesulfonate in a specific ratio and reacted in a suitable solvent to form a 1:1 salt structure. After fine post-processing steps such as separation and purification, a pure 3-ethyl + 5-methyl + 2- [ (2-aminoethoxy) methyl] - 4 - (2-chlorophenyl) - 6-methyl-1,4-dihydropyridine-3,5-dicarboxylate benzenesulfonate (1:1) product can be obtained.

There is a thing called 3-ethyl + 5-methyl + 2 - [ (2-aminoethoxy) methyl] - 4 - (2-chlorophenyl) - 6-methyl-1,4-dihydropyridine-3,5-dicarboxylate benzenesulfonate (1:1). This thing is in the market, and the judgment of the future is related to many things.
Looking at the field it belongs to, if it involves medicine, the prospect is closely related to the efficacy and safety. In today's world, the weight of people's health is increasing day by day, and the demand for medicine is vast. If this substance has a miraculous effect on the disease, and is safe and secure, and is approved for listing, it will be like a boat flowing downstream, and the market's demand will flourish. Pharmaceutical companies will also compete to chase, based on it, to develop new drugs and promote new products. The scale of the market may be like bamboo shoots, rising steadily.
If it is used in the chemical industry, its performance specificity determines its broad and narrow prospects. The chemical industry seeks innovation and diversity. If this substance can add benefits to the chemical process, or improve product quality, or reduce costs and increase efficiency, chemical factories will be regarded as treasures. The acceptance of the city will also be gradually expanded, from less use to wide use, and the future will suddenly brighten.
However, there are also worries. The road to research and development is full of thorns. The difficulty of synthesis and the high cost can become a roadblock. If the cost remains high, even if the performance is outstanding, the promotion in the city is like sailing against the current. And the bundle of regulations is increasingly stringent. If you can't comply with the rules, even if it is as good as a thousand, it will be difficult to enter the city.
Therefore, 3-ethyl + 5-methyl + 2 - [ (2-aminoethoxy) methyl] - 4 - (2-chlorophenyl) - 6-methyl-1,4-dihydropyridine-3,5-dicarboxylate benzenesulfonate (1:1) The market prospects, opportunities and challenges coexist, such as seeing flowers in the fog, need careful insight and careful weighing to see one or two.