(3S,4As,8As)-N-Tert-Butyl-2-[(2R,3R)-2-Hydroxy-3-[(3-Hydroxy-2-Methylbenzoyl)Amino]-4-(Phenylsulfanyl)Butyl]Decahydroisoquinoline-3-Carboxamide Methanesulfonate (1:1)

The chemical structure of this medicine has the following characteristics:
First, the skeleton of its structure is unique. This skeleton is like the beams and pillars of a building, laying the foundation for the overall structure. In terms of common chemical structure categories of medicines, this skeleton does not belong to several categories known to Xunchang, but it seems to come from ancient secrets and has its own unique shape. The arrangement of its carbon chains is tortuous, interlocking and unconventional geometric symmetry, like the layout of ancient strange doors and armor, seemingly disordered but contains mystery. This unique skeleton makes the identification of drug targets in the body unique, just like a special key to open a specific lock.
Second, the distribution of functional groups is very delicate. On the skeleton, functional groups are scattered, like stars in the night sky. However, this embellishment is not random, and the position of each functional group is closely related to the drug activity. There are functional groups with polarity, which are like ditches that can lead water flow, so that drug molecules can pass smoothly in the aqueous environment of the body, enhancing their solubility and transmission efficiency; and there are functional groups with reactivity, which are like warriors on standby at any time. They can undergo specific chemical reactions with target molecules in the body, or covalently bind, or form hydrogen bonds and other forces, so as to firmly lock the target and exert the drug effect.
Third, the stereochemical characteristics are significant. There are many chiral centers in the molecule, just like the human hand has left and right, and the three-dimensional configuration of this drug molecule also has a variety of. Molecules with different three-dimensional configurations behave very differently in living organisms. Like dancers with different postures, the "dance" and "reaction" displayed on the stage of life are different. This three-dimensional chemical feature not only affects the affinity of the drug and the target, but also affects the safety and effectiveness of the drug. If there is a slight mistake, it will be like a mistake, the efficacy of the drug may be greatly reduced, or even cause adverse reactions.
Fourth, the flexibility and rigidity of the overall structure coexist. Some structural areas, such as steel beams, are rigid and firm, maintaining the basic shape and stability of molecules, so that the drug will not be easily deformed and disintegrated in a complex internal environment; while some areas are like flexible silk, which can be bent and twisted appropriately. This flexibility allows drug molecules to adjust their posture according to the subtle shape changes of the target when binding to the target, just like a flexible dancer can fit the movements of different dance partners, which greatly enhances the degree of bonding and specificity, thereby enhancing the efficacy of the drug.

The mechanism of pharmacological action of this drug is related to the effect and operation of the drug in the human body. When a drug enters the body, it is like a surprise soldier entering the battle situation. Its effect must have a specific path and method.
Or act on human cells, such as a precise arrow hitting the bullseye, binding to the receptor on the cell surface. The receptor is like a cell's doorman, controlling the exchange of information inside and outside the cell. When a drug is combined with it, it is like holding a key to unlock the lock, triggering a series of biochemical reactions in the cell, or stimulating the activity of enzymes, or regulating gene expression, so that the cell function changes in the direction guided by the drug.
Or affect the transmission of neurotransmitters. The nervous system is also the command center of the human body. Neurotransmitters are the messengers of information transmission between nerve cells. Drugs may promote their release to make information transmission smoother; or inhibit their re-uptake, so that neurotransmitters stay in the synaptic gap for longer, thereby enhancing or weakening the signal transmission of the nervous system for therapeutic purposes.
Furthermore, or intervene in the human metabolic process. Human metabolism, such as the operation of complex machines, drugs can affect one part of it. For example, inhibiting the activity of an enzyme, the metabolic pathway involved in this enzyme is blocked, the corresponding metabolite production is changed, and disease symptoms are relieved.
It may also regulate the immune system. The immune system, the body's defense army. Drugs may enhance the activity of immune cells to greatly increase their ability to defend against enemies; or inhibit overactive immune responses to avoid autoimmune damage.
Pharmacological mechanisms of drugs are complex, but they all revolve around regulating human physiological and pathological processes, in order to treat diseases and restore health.

When this drug is used clinically, all kinds of precautions need to be paid attention to in detail.
First, those who use this drug must first check their physique. People have different endowments, or there are people who are allergic to the ingredients of this drug. Therefore, before using the drug, it is necessary to ask the history of past allergies in detail. If there are signs of allergies, it must not be used, so as not to cause allergic changes. If it is light, the skin is itchy and rash, the body is hot and uncomfortable, and if it is severe, it may cause asthma, tyranny, fainting and critical.
Second, the dosage of the drug is very important. It must be as instructed by the doctor, and it must not be increased or decreased without authorization. If the drug is not powerful enough, the disease cannot be cured; if it is more, it is afraid of the damage In children, the elderly and the infirm, qi, blood, yin and yang are already deficient, so the medication should be especially cautious, the dose should be light, and the reaction after the medication should be closely observed.
Third, pay attention to drug interactions. If the patient is using other drugs, inform the doctor. Cover the use of different drugs at the same time, or mutual help, or mutual resistance. If used in combination with certain drugs, or affect the efficacy of the drug, or increase its toxic and side effects. Doctors need to carefully review the compatibility of various drugs to avoid their harm and seek their benefits.
Fourth, during the medication period, the diet should also be paid attention to. Spicy, greasy, cold things, or hinder the spleen and stomach transport, or interact with drugs. Therefore, when taking medicine, it is advisable to eat light and easy-to-digest products to help the drug operate and protect the qi of the spleen and stomach.
Fifth, close observation of symptoms after taking medicine is required. If the symptoms are relieved after taking the medicine, it is a sign that the symptoms are consistent with the medicine; if the disease does not improve, or even worsens, or new discomfort occurs, stop taking the medicine immediately and inform the doctor so as to adjust the treatment method. Do not delay, so as not to delay the disease.

The adverse reactions of a certain drug are undesired harmful reactions during the course of medication. The adverse reactions of different drugs are different, and they are described in ancient Chinese.
There are drugs that can cause disharmony between the spleen and stomach. If a person takes the drug, they feel full of stomach and abdomen, seem to be blocked by things, have no taste, do not want to eat, and may see nausea and vomiting, even vomiting acid, or thin stool, all of which are symptoms of disturbance of the spleen and stomach. Because the drug has a superior taste, it damages the ability of the spleen and stomach to transport and transform, and the spleen and stomach elevate and reduce the loss of division.
There are also drugs that can affect the operation of qi and blood. Or make people's complexion dull, lip nail color pale, this is the sign of lack of qi and blood, after taking the medicine, the body is weak, tired, often wheezing, walking a little anxious, the heart palpitations are stunned, all of which are weak in qi and blood, and cannot nourish the internal organs and meridians. Or make qi and blood stagnant, local skin appears blue and purple petechiae, pain does not move, and the pain is even worse. This is because the drug causes poor qi and blood, and blood stasis is endogenous.
Furthermore, the drug may cause skin changes. Such as rash itching, rash out of different shapes, or miliary, or cloud slices, itching is unbearable, making people restless, scratching the rash and breaking water, easy to cause infection. This is mostly due to the human body's allergy to drugs, evil poison infiltrates the skin, qi and blood compete with evil qi, and occur on the body surface.
And there are drugs involving the liver and kidney. Those who injure the liver can cause swelling and pain in the ribs, bitter and dry mouth and throat, and yellow eyes and eyes. This is a sign of liver loss and dredging and bile overflow. In those who injure the kidney, it is common to have soreness at the waist and knee, dizziness and tinnitus, frequent urination at night, and even slippery nocturnal discharge in men and irregular menstruation in women. This is all due to drug damage to the essence of the liver and kidney, and dysfunction of the viscera.
All kinds of adverse reactions, doctors should carefully review the use of drugs, and patients should also be cautious when

Looking at this medicine today, its market prospects are related to many parties, and let me tell you in detail.
From the perspective of the world, people's livelihood is gradually improving, and people are paying more and more attention to health. If this medicine has significant effect and can solve the suffering of people's diseases, it must have a broad need. And now the medical way is prosperous, and the treatment of all kinds of diseases is seeking refinement. If this medicine can find a unique way and have a miraculous effect on a certain disease, it may emerge in the medical world, attract the attention of doctors, and then expand the market and be used by all people.
On the realm of commerce again, merchants pursue profits, but they also need the quality and effectiveness of medicine. If this drug is sold through the market trial, the reputation will gradually rise, and the praise will grow, it will surely lead to competition among the merchants, or there will be capital injection from all parties to help it spread to the world. And today's smooth traffic and convenient logistics can make this drug sold everywhere, regardless of geographical restrictions, so that everyone in the world can hear its name and use its medicine.
However, it is also necessary to consider the difficulties. In the medical profession, new drugs emerge one after another, and the competition is fierce. If this drug does not have outstanding ability, or it is difficult to match the edge of other drugs. And the people are used to using drugs, and they are used to believing in time-honored and well-known products. If they want to make new drugs win the hearts of the public, they must wait for time and achievements. Furthermore, the regulations of drug administration are becoming increasingly stringent, and this medicine must abide by the regulations in order to be able to travel unimpeded in the market.
In general, if the market prospect of this medicine is timely, geographical, and human, and if it adheres to the idea of helping the world, is based on efficacy, is based on quality, and seeks stability in both medical and business channels, it is expected to shine in the market and seek well-being for the world. Although there may be thorns in the road ahead, opportunities are also accompanied. It is necessary to be cautious and act in order to achieve long-term prosperity.