((3S,5R)-5-((1H-1,2,4-Triazol-1-Yl)Methyl)-5-(2,4-Difluorophenyl)Tetrahydrofuran-3-Yl)Methyl 4-Chlorobenzenesulfonate

This is the chemical name of ((3S, 5R) -5 - ((1H-1,2,4-triazole-1-yl) methyl) -5 - (2,4-difluorophenyl) tetrahydrofuran-3-yl) methyl 4-chlorobenzenesulfonate. To clarify its chemical structure, let me explain in detail.
First, the core structure of this compound is a tetrahydrofuran ring. At the 3rd and 5th positions of the tetrahydrofuran ring, there are specific groups connected, respectively. On the 5th position, (2,4-difluorophenyl) is connected on one side, and on the other side is ((1H-1,2,4-triazole-1-yl) methyl) group. Among them, 1,2,4-triazole is a five-membered heterocycle containing three nitrogen atoms, which is connected to the tetrahydrofuran ring at the 5th position with a 1-position nitrogen atom.
And at the 3rd position of the tetrahydrofuran ring, a substituted methyl group is connected, which in turn is connected to the 4-chlorobenzenesulfonate group. The 4-chlorobenzenesulfonate part is based on the benzene ring. The 4-position chlorine atom on the benzene ring is substituted. The sulfonic acid group is connected to the oxygen atom and then connected to the methyl group at the 3-position of the tetrahydrofuran ring.
This structure, the interaction of each group, endows this compound with unique chemical and physical properties. Or in the fields of organic synthesis, pharmaceutical chemistry, etc., it plays a specific role, because of its structural complexity and particularity, or it can exhibit unique reactivity and biological activity.

((3S, 5R) -5 - ((1H-1,2,4-triazole-1-yl) methyl) -5 - (2,4-difluorophenyl) tetrahydrofuran-3-yl) methyl 4-chlorobenzenesulfonate is widely used. In the field of medicine, it may be the key raw material for the creation of new antifungal drugs. The structure of Gain 1,2,4-triazole and difluorophenyl give it unique biological activities, which can effectively interfere with the metabolism and reproduction process of fungal cells, just like a magic weapon, directly attacking the key points of fungi, so as to achieve the purpose of fighting fungal infections.
In the field of pesticides, it is also promising. By virtue of its own structural characteristics, it may inhibit or kill specific pests and bacteria. In the ecological environment of farmland, it acts as a loyal guard to protect crops from pests and diseases, ensure the robust growth and harvest of crops, and maintain the ecological balance of farmland.
In addition, in the field of organic synthetic chemistry, this compound may act as an important intermediate. Chemists can derive a series of organic compounds with different functions and properties by ingeniously modifying and transforming their structures, which is like building a colorful organic compound building, contributing to the development of organic synthetic chemistry and expanding new research directions and application fields.

To prepare ((3S, 5R) -5- ((1H-1,2,4-triazole-1-yl) methyl) -5- (2,4-difluorophenyl) tetrahydrofuran-3-yl) methyl 4-chlorobenzenesulfonate, the method is as follows:
First take an appropriate amount of (3S, 5R) -5- ((1H-1,2,4-triazole-1-yl) methyl) -5- (2,4-difluorophenyl) tetrahydrofuran-3-ol and place it in a clean reaction vessel. In addition, 4-chlorobenzenesulfonyl chloride is prepared and slowly added dropwise to the container where the above alcohol compounds are located. At the same time, the temperature of the reaction system needs to be controlled within an appropriate range, generally maintained at a low temperature, such as 0-5 ° C. This is because the reaction is more active, low temperature is conducive to the smooth progress of the reaction and reduces the occurrence of side reactions.
After the dropwise addition is completed, an appropriate amount of alkali, such as triethylamine, is added to it. The function of the alkali is to neutralize the hydrogen chloride produced during the reaction and promote the positive progress of the reaction. Then, the reaction mixture is gently stirred at an appropriate temperature, such as room temperature to 40 ° C, for several hours. The specific duration depends on the monitoring of the reaction process. The reaction can be tracked by means of thin layer chromatography (TLC). When the raw material point is basically eliminated, the reaction is basically completed.
After the reaction is completed, an appropriate amount of water is added to the reaction solution to quench the unreacted reagents, and then an organic solvent, such as dichloromethane, is extracted. After multiple extractions, the organic phase is combined. The organic phase is washed with water and saturated salt water to remove residual impurities and water-soluble substances. Subsequently, the organic phase is dried with anhydrous sodium sulfate, the desiccant is filtered off, and the organic solvent is removed by reduced pressure distillation to obtain a crude product.
The crude product is further purified by column chromatography, a suitable eluent, such as a mixed solvent of petroleum ether and ethyl acetate, is selected, and the ratio of the two is adjusted according to the polarity of the product. Carefully separated, high-purity ((3S, 5R) -5- ((1H-1,2,4-triazole-1-yl) methyl) -5- (2,4-difluorophenyl) tetrahydrofuran-3-yl) methyl 4-chlorobenzenesulfonate can be obtained.

I don't know what the market price of ((3S, 5R) -5- ((1H-1,2,4-triazole-1-yl) methyl) -5- (2,4-difluorophenyl) tetrahydrofuran-3-yl) methyl 4-chlorobenzenesulfonate is. This compound is unusual and common, or it belongs to fine chemicals, pharmaceutical intermediates and the like.
View of "Tiangong Kaiwu", which records many agricultural and industrial skills and products, etc., and the price of such compounds is rare. Chemical synthesis was not as developed as it is today in Gaigu, and no such fine compounds have been circulated in the market.
If you want to know the market price of this product, you should consult the chemical raw material trading platform and chemical suppliers at this time. Or due to different purity and batch, the price difference is quite large. Those with high purity and large batch will have different prices. However, I have no real-time business information, so it is difficult to determine the price.

((3S, 5R) -5- ((1H-1,2,4-triazole-1-yl) methyl) -5- (2,4-difluorophenyl) tetrahydrofuran-3-yl) methyl 4-chlorobenzenesulfonate is a matter of great importance in terms of its safety and stability.
Test its safety. If it is placed in a complex environment, it is necessary to be careful to check whether it is harmful to people, objects and surrounding ecology. For the human body, will it damage the viscera, disturb qi and blood operation through oral, percutaneous or inhalation? Will it cause skin allergies, poison meridians, or even affect the mind? Is there any erosion and damage to the surrounding ecology, soil, flowers, trees, insects, fish, birds and beasts, etc., disturbing the order of nature?
In terms of its stability, under the conditions of different days (temperature, humidity changes) and geographical conditions (environmental characteristics of different regions), its own structure is stable and difficult to decompose and mutate. If the temperature rises or drops sharply, will it cause its chemical bonds to break and new pests will be born; if the humidity is high, will it absorb moisture and mildew, changing the original nature. And in the process of long-term storage, whether it can maintain its inherent state and not change its quality depends on whether it can last for a long time and play its intended role.
Only by exploring in detail and understanding its performance in various situations can we ensure that it is safe and stable in application, without causing disasters, and make the best use of it.