As a leading ((3S,5R)-5-((1H-1,2,4-Triazol-1-Yl)Methyl)-5-(2,4-Difluorophenyl)-Tetrahydrofuran-3-Yl)Methyl 4-Methylbenzenesulfonate supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical structure of (3S, 5R) -5- ((1H-1,2,4-triazole-1-yl) methyl) -5- (2,4-difluorophenyl) tetrahydrofuran-3-yl) methyl 4-methylbenzenesulfonate?
(3S, 5R) -5- ((1H-1,2,4-triazole-1-yl) methyl) -5- (2,4-difluorophenyl) tetrahydroimidazole-3-yl) methyl + 4-methylbenzenesulfonate, this is an organic compound, its delicate structure needs to follow the rules of organic chemistry and nomenclature analysis.
I follow the ancient style of "Tiangong Kaiwu" and describe it in text. Looking at this compound, it is cleverly connected by many groups. (3S, 5R) shows its three-dimensional configuration, which is related to the arrangement of molecular space, such as everything in heaven and earth. 5- ((1H-1,2,4-triazole-1-yl) methyl), in which the triazole group is like the pillar of the building, and the methyl group is part of its extension beam, which plays a part in the structure. 5- (2,4-difluorophenyl), difluorophenyl is like a delicate masonry, inlaid in a specific position. Tetrahydroimidazole-3-yl) methyl, tetrahydroimidazole ring If the strong cornerstone, methyl adds its changes. And 4-methylbenzenesulfonate, like a crown, imparts different properties to the whole molecule.
In its structure, each atom is connected by a covalent bond, such as a silk string in series with pearls. Atoms such as carbon, hydrogen, nitrogen, oxygen, and fluorine are arranged according to their respective characteristics to form a unique three-dimensional structure. This structure affects the physical and chemical properties of compounds, such as solubility, stability, and reactivity. The endowment of a person determines their words and deeds. The wonders of chemical structures are just like the work of creation. Using elements as a pen, a wonderful picture is drawn, showing the secrets of nature and the brilliance of human wisdom.
What are the main uses of (3S, 5R) -5- ((1H-1,2,4-triazole-1-yl) methyl) -5- (2,4-difluorophenyl) tetrahydrofuran-3-yl) methyl 4-methylbenzenesulfonate?
(3S, 5R) -5- ((1H-1,2,4-triazole-1-yl) methyl) -5- (2,4-difluorophenyl) tetrahydroimidazole-3-yl) methyl 4-methylbenzenesulfonate, this compound has important uses in the field of medicinal chemistry.
First, at the level of drug development, it may serve as a key intermediate. By modifying and modifying its structure, it may be possible to create drugs with novel pharmacological activities. For example, by adjusting the linking group or substituent, the affinity and selectivity of the drug for specific targets can be optimized, and then specific therapeutic drugs for diseases such as fungal infections and tumors can be developed.
Second, in the field of organic synthesis, this compound can be used as a cornerstone for building complex molecular structures. Due to its unique structural characteristics, it can combine with other organic molecules through various chemical reactions, such as nucleophilic substitution, coupling reactions, etc., to build more complex organic compounds, providing new paths and possibilities for the development of organic synthetic chemistry.
Third, in terms of biological activity research, related experiments based on it can help scientists to deeply explore specific biological pathways and molecular interaction mechanisms. By observing the binding mode of this compound with targets in vivo and the biological effects triggered, it can improve the understanding of life processes and provide a solid theoretical basis for subsequent drug design and development.
What is the preparation method of (3S, 5R) -5- ((1H-1,2,4-triazole-1-yl) methyl) -5- (2,4-difluorophenyl) tetrahydrofuran-3-yl) methyl 4-methylbenzenesulfonate?
To prepare (3S, 5R) -5- ((1H-1,2,4-triazole-1-yl) methyl) -5- (2,4-difluorophenyl) tetrahydropyrimidine-3-yl) methyl 4-methylbenzenesulfonate, the method is as follows:
Take an appropriate amount of 2,4-difluorobenzaldehyde, place it in a clean reactor, use anhydrous ethanol as a solvent, add a little basic catalyst, and stir well. Subsequently, the tetrahydropyrimidine derivative containing a specific structure is slowly added dropwise, the reaction temperature is controlled in an appropriate range, and the number of stirrings is continued to make the two fully react to form the intermediate A. This step requires attention to the regulation of temperature to prevent the occurrence of side reactions.
Transfer the intermediate product A to another reaction device, add an appropriate amount of 1- (chloromethyl) -1H-1,2,4-triazole, use N, N-dimethylformamide as the solvent, add an appropriate amount of acid binding agent, heat up to a certain extent, and maintain a constant temperature reaction for a period of time. During this period, the reaction process is closely monitored, and the reaction endpoint is determined by means of thin-layer chromatography, etc., to obtain the intermediate product B.
The intermediate product B is treated. After conventional operations such as extraction, washing, and drying, it is mixed with 4-methylbenzenesulfonyl chloride, and the reaction is carried out with dichloromethane as a solvent and catalyzed by an organic base. During the reaction process, the reaction conditions, including temperature, pH, etc., are strictly controlled. After the reaction is completed, the target product is separated and purified by column chromatography, the fractions of the target product are carefully collected, and then recrystallized. Finally, pure (3S, 5R) -5- ((1H-1,2,4-triazole-1-yl) methyl) -5- (2,4-difluorophenyl) tetrahydropyrimidine-3-yl) methyl 4-methylbenzenesulfonate is obtained. The whole preparation process requires attention to the precise control of the reaction conditions, and the operation of each step is meticulous to obtain the ideal yield and purity.
What are the Quality Standards for (3S, 5R) -5- ((1H-1,2,4-triazole-1-yl) methyl) -5- (2,4-difluorophenyl) tetrahydrofuran-3-yl) methyl 4-methylbenzenesulfonate?
(3S, 5R) -5- ((1H-1,2,4-triazole-1-yl) methyl) -5- (2,4-difluorophenyl) tetrahydropyrrole-3-yl) methyl 4-methylbenzenesulfonate is an organic compound. The Quality Standard is critical for many properties and applications of this compound.
The purity standard of this compound is of paramount importance. High purity can ensure stable properties and reliable results in various reactions and applications. The impurity content must be strictly controlled, otherwise its chemical reaction activity and product quality may be affected. For example, too many impurities may occur in drug synthesis or cause side reactions, interfering with the expected pharmacological effect.
Melting point range is also an important Quality Standard. The compound should have a specific melting point range. If the melting point deviates from the normal range, it may suggest that there is a problem with its purity, or the crystal structure changes, which will affect its physical and chemical properties.
The standard for its chemical stability is indispensable. Under specific storage conditions, the chemical structure and properties should be stable, and no reactions such as degradation and oxidation will occur. Otherwise, the quality will decline during storage and cannot meet the requirements for use.
In addition, the solubility standard of this compound is also worthy of attention. In specific solvents, it should have the expected solubility, which is related to its dispersion, reaction and application in solution. For example, in the preparation of preparations, good solubility is of great significance for the release and absorption of active ingredients of drugs.
The Quality Standards for this compound cover purity, melting point, chemical stability, solubility, etc. All aspects are interrelated and affect each other to ensure its reliable application in scientific research, industrial production and medicine.
What are the market prospects for (3S, 5R) -5- ((1H-1,2,4-triazole-1-yl) methyl) -5- (2,4-difluorophenyl) tetrahydrofuran-3-yl) methyl 4-methylbenzenesulfonate?
(3S, 5R) -5- ((1H-1,2,4-triazole-1-yl) methyl) -5- (2,4-difluorophenyl) tetrahydropyrrole-3-yl) methyl 4-methylbenzenesulfonate, a fine chemical substance. In the current market, its prospects are complex, and advantages and disadvantages coexist.
Looking at its advantages, with the continuous expansion of the field of pharmaceutical research and development, the demand for fine chemicals with specific structures is increasing. The unique chemical structure of this compound may make it a key intermediate in the process of new drug development. For example, in the development of antifungal drugs, 1,2,4-triazole structural units often exhibit significant biological activity, which may help to develop more efficient antifungal agents, thus opening up a broad market space for this compound.
Furthermore, with the development of materials science, fluorinated compounds are favored in the preparation of high-performance materials due to their unique physical and chemical properties, such as high stability and low surface energy. The 2,4-difluorophenyl contained in this compound may make it useful in the field of special materials, such as the preparation of high-performance polymers, surfactants, etc., thus further expanding the market demand.
However, its market also has challenges. The synthesis of fine chemicals usually involves complex processes and harsh reaction conditions, and the production cost is high. This compound has a complex structure, and there are many synthesis steps. It requires extremely high requirements for reaction equipment and technicians, which increases production costs and weakens market competitiveness.
At the same time, the global supervision of chemicals is becoming increasingly strict. The compound needs to meet various environmental protection and safety regulations during production and use. If it cannot comply with changes in regulations in time, or face difficulties such as production restrictions and market restrictions.
In summary, (3S, 5R) -5- ((1H-1,2,4-triazole-1-yl) methyl) -5- (2,4-difluorophenyl) tetrahydropyrrole-3-yl) methyl 4-methylbenzenesulfonate has addressable market opportunities, but also needs to deal with many challenges such as costs and regulations in order to gain a firm foothold in the market and achieve good development.