What is the chemical structure of (3S-cis) -4-chlorobenzenesulfonic acid [5- (2,4-difluorophenyl) tetrahydro-5- (1H-1,2,4-triazole-1-ylmethyl) -3-furyl] methyl ester?
The chemical structure of (3S-cis) -4-hydroxyphenylacetic acid [5- (2,4-diethylphenyl) tetraamine-5- (1H-1,2,4-triazole-1-ylmethyl) -3-pyridyl] methyl ether is an interesting problem in the field of organic chemistry.
Looking at this compound, its structure is complex and delicate. From the beginning of naming, (3S-cis) indicates its stereochemical configuration, which is a key element of molecular spatial arrangement and has a profound impact on its physical and chemical properties. 4-Hydroxyphenylacetic acid part, with hydroxyl and carboxyl groups attached to the benzene ring. As a common aromatic structure, the benzene ring endows the molecule with certain stability and conjugation characteristics. The presence of hydroxyl groups can participate in the formation of hydrogen bonds and enhance intermolecular forces; carboxyl groups are acidic and can neutralize with bases.
Looking at [5- (2,4-diethylphenyl) tetraamine-5- (1H-1,2,4-triazole-1-ylmethyl) -3-pyridyl] methyl ether fragments. The introduction of 2,4-diethylphenyl and ethyl alters the electron cloud density of the phenyl ring and affects the electrophilic and nucleophilic reactivity of the molecule. The tetraamine structure, the lone pair of electrons of the nitrogen atom makes it have certain basicity and coordination ability. 1H-1,2,4-triazole-1-yl methyl, the triazole ring is a nitrogen-containing heterocycle, which has a unique electronic structure and biological activity, and is widely used in many drugs and materials. Pyridyl is also a nitrogen-containing heterocycle, and the basicity and aromatics of the nitrogen atom add different chemical properties to the molecule. The connection of methyl ethers allows the parts to be connected, and the stability of ether bonds is crucial to the stability of the overall structure.
To sum up, the chemical structure of this compound is complex and orderly, and its parts cooperate with each other, giving it unique physical and chemical properties, which may have potential application value in organic synthesis, drug development and other fields.
What are the main uses of (3S-cis) -4-chlorobenzenesulfonic acid [5- (2,4-difluorophenyl) tetrahydro-5- (1H-1,2,4-triazole-1-ylmethyl) -3-furyl] methyl ester?
(3S-cis) -4-hydroxyphenylacetic acid [5- (2,4-diethylphenyl) tetraamino-5- (1H-1,2,4-triazole-1-ylmethyl) -3-pyridyl] methyl ether, which is widely used and plays an important role in the fields of medicine and chemical industry.
In the field of medicine, it can be used as a key intermediate in drug synthesis. Taking the development of drugs for the treatment of neurological diseases as an example, because of its special chemical structure, it can precisely bind to specific nerve receptors. By chemically modifying and optimizing the structure of the substance, innovative drugs with better curative effect and fewer side effects may be developed. For example, after structural modification, it may improve the permeability of the drug to the blood-brain barrier, making it easier for the drug to reach the brain lesion area, thereby enhancing the therapeutic effect.
In the chemical industry, it plays a key role in the synthesis of polymer materials. It can be used as a functional monomer to participate in polymer polymerization reactions, giving the material unique properties. For example, it can be introduced into the synthesis process of polyester materials, which may improve the thermal stability and mechanical properties of the material. Due to the special groups it contains, it can form a strong interaction with the polyester molecular chain, enhancing the force between the molecular chains, thereby improving the overall performance of the material and meeting the high-performance requirements of materials in high-end fields such as aerospace and automotive manufacturing.
(3S-cis) -4-chlorobenzenesulfonic acid [5- (2,4-difluorophenyl) tetrahydro-5- (1H-1,2,4-triazole-1-ylmethyl) -3-furyl] methyl ester What are the precautions in the production process?
Preparation of (3S-cis) -4-hydroxyproline [5- (2,4-divinylphenyl) tetranitrogen-5- (1H-1,2,4-triazole-1-ylmethyl) - 3-imidazolyl] methyl ether has the following precautions in the production process:
First, the control of raw materials. It is necessary to ensure that (3S-cis) -4-hydroxyproline, 2,4-divinylphenyl related raw materials and 1,2,4-triazole-1-ylmethyl and other raw materials are of high quality and free of impurities. If there are impurities, or the reaction is skewed, the product is impure, such as impurities participating in the reaction, or by-products, disturbing the main reaction process, making it difficult to separate and purify the product.
Second, the consideration of reaction conditions. Temperature needs to be precisely controlled, and the reaction in different stages has different temperature effects. If the temperature is too high, it may cause overreaction, trigger side reactions, or even cause the decomposition of raw materials and products; if the temperature is too low, the reaction rate will be slow, time-consuming and lengthy, and the yield will decrease. The reaction time should also be strictly controlled. If the time is insufficient, the reaction will not be completed, and the amount of product will be small. If it takes too long, it may cause overreaction, which will damage the quality of the product.
Third, the consideration Choose the appropriate solvent to consider its effect on the solubility of the reactants and the reaction process. Good solvents can promote the contact of the reactants and facilitate the reaction; improper solvents, or resist the reaction. Choose the appropriate catalyst to increase the reaction rate and reduce the activation energy of the reaction. However, the amount of catalyst needs to be appropriate, too much or too little, both affect the reaction effect.
Fourth, the operation process is rigorous. The order of adding raw materials is particular, and the improper order or the reaction start is not good. Stirring should be uniform, so that the reactants are fully mixed and the reaction is uniform. The reaction equipment must be clean and free from the introduction of impurities. When separating and purifying the product, choose the appropriate method, such as recrystallization, column chromatography, etc., to achieve the purpose of high
What are the market prospects for (3S-cis) -4-chlorobenzenesulfonic acid [5- (2,4-difluorophenyl) tetrahydro-5- (1H-1,2,4-triazole-1-ylmethyl) -3-furyl] methyl ester?
(3S-cis) - 4 -hydroxyphenylacetic acid [5 - (2,4 -divinylphenyl) tetrazol - 5 - (1H - 1,2,4 -triazole - 1 -ylmethyl) - 3 -pyridyl] methyl ether What is the market prospect?
Guanfuji (3S-cis) -4-hydroxyphenylacetic acid [5- (2,4-divinylphenyl) tetrazol-5- (1H-1,2,4-triazole-1-ylmethyl) -3-pyridyl] methyl ether is a unique compound in the field of organic chemistry. Its structure is exquisite and composed of many parts.
In the field of medicine, its structure contains specific functional groups or has affinity for specific receptors, which in turn shows unique biological activities. For example, the hydroxyphenylacetic acid part of it may participate in the biochemical reactions of the human body and affect the enzymes or signaling pathways related to certain diseases. And structures such as triazolyl and pyridyl may also work synergistically to provide new opportunities for drug research and development. Today, the pharmaceutical industry has an increasing demand for new, efficient and low-toxicity drugs. If this compound can be further studied to confirm its pharmacological activity and safety, it will surely find a place in the pharmaceutical market, or become a key drug for the treatment of specific diseases, with promising prospects.
In the field of materials science, the unique structure of this compound may endow it with special physicochemical properties. For example, in photoelectric materials, its conjugate structure may affect the electron transport performance. If it is properly regulated, it may be applied to organic Light Emitting Diodes (OLEDs), solar cells and other fields. At present, materials science is constantly seeking new materials with excellent performance. If this compound can meet the relevant performance requirements, it will surely emerge in the material market and promote technological innovation in related fields.
However, its market prospects are not smooth sailing. On the one hand, the synthesis process of compounds may be complex, and cost control becomes the key. If efficient and low-cost synthesis cannot be achieved, large-scale production and marketing activities will be hindered. On the other hand, safety and environmental friendliness need to be strictly evaluated. In today's era of environmental protection and health, it is difficult to gain market recognition if it cannot meet relevant standards. But overall, with in-depth research and rational development, the market prospect of this compound is still promising.
What are the synthetic methods of (3S-cis) -4-chlorobenzenesulfonic acid [5- (2,4-difluorophenyl) tetrahydro-5- (1H-1,2,4-triazole-1-ylmethyl) -3-furyl] methyl ester?
To prepare (3S-cis) -4-bromobenzenesulfonic acid [5- (2,4-diethylphenyl) tetranitrogen-5- (1H-1,2,4-triazole-1-ylmethyl) -3-pyridyl] methyl sulfonamide, there are several methods. This synthesis method requires many steps and skills.
The choice of raw materials, 2,4-diethylbenzene, 1,2,4-triazole-1-ylmethyl related reagents, etc. are all important starting materials. At the beginning of the reaction, benzene compounds containing suitable substituents can be interacted with bromine reagents to introduce bromine atoms to obtain bromine-containing intermediates. This step requires controlling the reaction conditions, such as temperature, solvent, etc., so that bromine is substituted at the desired position to obtain an analogue of (3S-cis) -4-bromobenzene.
Then, react with a sulfonating reagent to obtain (3S-cis) -4-bromobenzene sulfonic acid. In this process, pay attention to the position and selectivity of the sulfonic acid group introduction, so that the sulfonic acid group is accurately connected to the target check point.
For the construction of the 5- (2,4-diethylphenyl) tetranitrogen moiety, the tetranitrogen structure can be introduced by a substrate containing diethylphenyl through a multi-step reaction. For example, by suitable nitrogen-containing reagents, under suitable conditions, the tetranitrogen ring system is gradually formed, and the 2,4-diethylphenyl group is properly connected to it.
And 5- (1H - 1,2,4 - triazole - 1 - ylmethyl) - 3 - pyridyl moiety, the compound containing the pyridyl group can be prepared first, and then the 1,2,4 - triazole - 1 - ylmethyl is introduced into the appropriate position of the pyridine ring. This step can be achieved by means of reactions such as nucleophilic substitution, pay attention to the reactivity and selectivity, and make the substituent access accurate check point.
Finally, the above parts are connected with appropriate reactions, such as condensation reactions, to form the target product (3S-cis) -4-bromobenzenesulfonic acid [5- (2,4-diethylphenyl) tetranitrogen-5- (1H-1,2,4-triazole-1-ylmethyl) -3-pyridyl] methylsulfonamide. Each step requires precise control of conditions, including temperature, pH, reaction time, etc., and proper separation and purification of intermediate products to ensure the purity and yield of the final product.