What is the chemical structure of the disodium salt 4- (2,4-dimethylphenylazo) -3-hydroxy-2,7-naphthalene disulfonate?
The structure of 4 - (2,4 - dimethylbenzyl carbonyl) - 3 - methoxy - 2,7 - diethyl naphthalate can be viewed in this way.
First, the naphthalene ring, which is the core framework of the structure. Naphthalene is composed of two fused benzene rings, which are aromatic and provide a stable framework in the compound. For 2,7 - diethyl naphthalate, the 2nd and 7th positions of the naphthalene ring are connected with carboxyl groups and ethanol esterified ester groups, respectively. The esterification of carboxyl group with ethanol gives the compound specific chemical properties and steric resistance.
Looking at the 4 - (2,4 -dimethylbenzyl carbonyl) part again. Benzyl is benzyl, that is, benzene ring-linked methylene-CH ² -. The methyl group is introduced at the 2,4 position to form 2,4-dimethylbenzyl. This benzyl group is connected to the 4 position of the naphthalene ring through carbonyl-CO -. Carbonyl is a strongly polar group, which affects the electron cloud distribution and reactivity of the molecule.
And 3-methoxy, that is, methoxy-OCH, is connected to the third position of the naphthalene ring. Methoxy has a electron supply effect, which can change the electron cloud density of the naphthalene ring, which in turn affects the physical and chemical properties of the compound.
This compound has a complex structure, and the interaction of various groups determines its properties such as solubility, stability, and reactivity. The spatial arrangement and electronic effects of different groups are intertwined, which makes this compound have a unique position and application potential in the field of chemistry.
What are the uses of 4- (2,4-dimethylphenylazo) -3-hydroxy-2,7-naphthalene disulfonate disodium salt?
4- (2,4-Dimethylbenzyl ethyl ether) - 3-methoxy-2,7-naphthalene disulfonic acid disodium salt, this is an organic compound, which has important uses in many fields.
In the field of medicinal chemistry, it can be used as a key intermediate in drug synthesis. Due to its unique chemical structure, it can introduce specific functional groups into drug molecules, which in turn endows drugs with new properties, such as improving drug solubility, stability, and enhancing drug affinity with targets. For example, when developing new antimicrobial drugs, this compound is used to build specific pharmacophore to enhance drug antibacterial activity and selectivity.
In the field of materials science, it can be used to prepare functional materials. For example, by copolymerizing with other polymers, materials can be endowed with special optical and electrical properties. For example, the preparation of polymer materials with fluorescent properties can be used in biological imaging, optical sensors and other fields. By virtue of its structural characteristics, luminescent centers can be constructed in the material to achieve specific light signal responses.
In the field of dye industry, this compound is also of great value. Because it contains chromophore and sulfonic acid groups, it can be used as raw materials for the synthesis of new dyes. Sulfonic acid groups can enhance the water solubility and dyeing fastness of dyes, and are suitable for dyeing a variety of fiber materials, such as natural fibers such as cotton, hemp, silk, and man-made fibers such as polyester and nylon, which can dye bright and long-lasting colors.
With its unique chemical structure, this compound plays a key role in the pharmaceutical, materials, dye and other industries, promoting technological innovation and product upgrading in various fields.
What is the preparation method of disodium salt of 4- (2,4-dimethylphenylazo) -3-hydroxy-2,7-naphthalene disulfonate?
To prepare 4- (2,4-dimethylbenzyl) -3-fluoro-2,7-dicobalt naphthalate, the following method can be used:
Prepare 2,4-dimethylbenzyl halide and 3-fluoro-2,7-naphthalic anhydride as starting materials. In a suitable reaction vessel, add an appropriate amount of organic solvent, such as N, N-dimethylformamide (DMF) or dichloromethane, and make it dissolve uniformly.
The reaction system is cooled to an appropriate low temperature, about 0 ° C to 5 ° C. Slowly add an alkali, such as potassium carbonate or sodium carbonate, to activate 3-fluoro-2,7-naphthalene dianhydride to make it more reactive. The ratio of base to starting material needs to be precisely prepared according to stoichiometry to ensure sufficient reaction.
After the alkali is added, keep stirring at low temperature for a while to bring the system to an equilibrium state. Then, add 2,4-dimethylbenzyl halide dropwise to control the dripping speed to prevent overreaction. Add it, heat it up to room temperature, and continue to stir for the number of reactions. During this period, the reaction process can be monitored by thin-layer chromatography (TLC) to ensure that the starting material is completely consumed.
When the reaction is completed, pour the reaction solution into an appropriate amount of water, extract the product with an organic solvent, and combine the organic phases after multiple extractions. The organic phase was dried with anhydrous sodium sulfate, the desiccant was filtered off, and the organic solvent was removed by vacuum distillation to obtain a crude product.
The crude product can be purified by column chromatography, using silica gel as the stationary phase, selecting a suitable eluent, such as a mixed solvent of petroleum ether and ethyl acetate, layer elution, collecting the eluent containing the pure product, and evaporating the solvent to obtain the pure product of 4- (2,4-dimethylbenzyl) -3-fluoro-2,7-dicobalt naphthalate. During the whole preparation process, attention should be paid to the precise control of reaction conditions, the proper allocation of material proportions, and the standard operation of each step to obtain satisfactory yield and purity.
What are the physical properties of disodium salt of 4- (2,4-dimethylphenylazo) -3-hydroxy-2,7-naphthalene disulfonate?
4- (2,4-dimethylbenzyl ethyl ether) - 3-fluoryl-2,7-dibutyl naphthalate, this physical property is quite complex, let me tell you one by one.
First of all, its appearance is often colorless to light yellow oily liquid, at room temperature, the appearance is translucent, like a clear spring, without significant color and precipitation. Its smell is also relatively weak, only a slight fragrance, not pungent, not disturbing.
As for the melting point, due to the interaction of various groups in its structure, its melting point is in a relatively low range, between -20 ° C and -10 ° C. This property allows it to maintain a liquid state at low temperatures, with good fluidity. The boiling point is around 300 ° C to 320 ° C due to intermolecular forces. At this temperature, the substance will transform from liquid to gaseous.
In terms of solubility, the substance exhibits lipophilicity. It can be miscible with many organic solvents, such as toluene, xylene and other hydrocarbon solvents in any ratio. It also has a certain solubility in polar organic solvents such as ethanol and acetone. However, it is almost insoluble in water. This is because the hydrophobic group dominates in the molecular structure.
The density is slightly larger than that of water, about 1.1-1.2 g/cm ³. When placed in water, it will slowly sink. Its stability is acceptable. Under conventional temperature, light and humidity conditions, it can be stored for a long time without significant chemical changes. When exposed to strong oxidants, strong acids and bases, the structure may be damaged and chemical reactions occur. The physical properties of this substance make it useful in the chemical industry, materials, and other fields. It can be used as a raw material for the production of certain special materials, and can also be used as an organic solvent to participate in specific reactions.
What are the chemical properties of disodium salt of 4- (2,4-dimethylphenylazo) -3-hydroxy-2,7-naphthalene disulfonate?
The disodium salt of 4- (2,4-dimethylbenzyl isonitrile) -3-fluoro-2,7-naphthalene disulfonate is an organic compound with unique chemical properties, which is of great significance for in-depth understanding of it in organic synthesis, materials science, and drug research and development. The following is an analysis from many aspects.
From the perspective of stability, the structure of this compound contains groups such as naphthalene ring, sulfonic acid group, fluorine atom, and dimethylbenzyl isonitrile. Naphthalene ring has a conjugated system, which imparts certain stability to the molecule; sulfonic acid group has strong polarity and water solubility, which can form salts and increase the stability of the compound in polar solvents; fluorine atom has strong electronegativity, which can Under normal conditions, the compound is stable in a dry and normal temperature environment. However, in the case of strong acids, strong bases or high temperatures, chemical reactions may occur and cause structural changes. For example, in a strong base environment, sulfonate sodium salts may undergo ion exchange reactions with bases; at high temperatures, some chemical bonds in the molecule may be broken due to increased energy.
In terms of solubility, sulfonate sodium salts make compounds have good water solubility, because sulfonate groups can form hydrogen bonds with water molecules, which prompts compounds to disperse in water. Non-polar groups such as naphthalene rings and dimethylbenzyl groups limit their solubility in non-polar organic solvents such as n-hexane and benzene. In medium polar organic solvents such as ethanol and acetone, the solubility may be limited due to the polar and non-polar parts of the molecule, depending on the specific polarity of the solvent and the interaction between molecules.
In terms of reactivity, fluorine atoms can participate in nucleophilic substitution reactions, because it can change the electron cloud density of the benzene ring and attract the attack of nucleophilic reagents; dimethyl benzyl isonitrile has high reactivity, and the electron cloud density of the isonitrile carbon atom is low, making it vulnerable to nucleophilic reagents and insertion reactions. Although the sulfonic acid group is relatively stable, under certain conditions, such as interacting with strong dehydrating agents or undergoing a sulfonation reverse reaction, the sulfonic acid group is removed.
In addition, the naphthalene ring in this compound can undergo electrophilic substitution reaction. Due to the high electron cloud density of the naphthalene ring, it is easy to be attacked by electrophilic reagents, and the reactivity is higher than that of the benzene ring, and the reaction check point is mostly at the α position.
In summary, the stability, solubility and reactivity of 4- (2,4-dimethylbenzyl isonitrile) -3-fluoro-2,7-naphthalene disulfonic acid disodium salt are affected by various groups in its structure, and it presents various chemical properties under different environments and reaction conditions.
